Denosteorel 60 mg Injection 1 ml belongs to a group of medicines called RANK ligand inhibitors used to treat osteoporosis in postmenopausal women and men who have an increased risk of fracture. Denosteorel 60 mg Injection 1 ml is also used to treat bone loss due to reduced hormone levels caused by surgery or due to treatment with medicines in patients with prostate cancer. It is also used to treat bone loss occurring due to long-term treatment with glucocorticoids in patients who are at an increased risk of fractures. Denosteorel 60 mg Injection 1 ml may also be used to reduce the risk of fractures in people with multiple myeloma, giant cell tumours of the bone and to treat high calcium levels caused due to cancer. Denosteorel 60 mg Injection 1 ml binds to a protein on RANK ligand on osteoclast (cells that cause bone breakdown) and inhibits their formation, functioning and survival. Thereby decreases bone breakdown, increases bone density, and strengthens the bone. Denosteorel 60 mg Injection 1 ml treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slows the tumour growth. Denosteorel 60 mg Injection 1 ml helps treat high calcium levels by decreasing bone breakdown as the breakdown of the bones releases calcium. Denosteorel 60 mg Injection 1 ml makes the bones stronger and less likely to break.

FAQs

How does Denosteorel 60 mg Injection 1 ml work?

Denosteorel 60 mg Injection 1 ml binds to a protein on RANK ligand on osteoclast (cells that cause bone breakdown) and inhibits their formation, functioning and survival. Thereby decreases bone breakdown, increases bone density, and strengthens the bone. Denosteorel 60 mg Injection 1 ml makes the bones stronger and less likely to break.

Does Denosteorel 60 mg Injection 1 ml cause osteonecrosis?

Osteonecrosis of the jaw (bone damage in the jaw) might be a side-effect of Denosteorel 60 mg Injection 1 ml. The risk increases in people taking Denosteorel 60 mg Injection 1 ml for longer durations. It might also occur upon discontinuation of the treatment. Maintain good dental hygiene and receive regular dental check-ups whilst on treatment with Denosteorel 60 mg Injection 1 ml. Inform your doctor if you have dental problems, gum disease, planned tooth extractions, cancer, if you smoke, or are taking bisphosphonates or corticosteroids.

Is Denosteorel 60 mg Injection 1 ml used to treat high calcium levels?

Breakdown of bones releases calcium and causes hypercalcemia (high calcium levels in the blood). Denosteorel 60 mg Injection 1 ml helps treat high calcium levels by decreasing bone breakdown.

Does Denosteorel 60 mg Injection 1 ml cause unusual thigh bone fractures?

Unusual thigh bone fractures might occur whilst on treatment with Denosteorel 60 mg Injection 1 ml. Consult your doctor if you experience new or unusual pain in the thigh, hip, or groin.

Is Denosteorel 60 mg Injection 1 ml used to treat giant cell tumours of the bone?

Denosteorel 60 mg Injection 1 ml treats giant cell tumour of bone (GCTB) by blocking certain receptors in the tumour cells, thereby slows the tumour growth. Giant cell tumour of the bone is a non-cancerous tumour that typically grows at the ends of long bones.

Does Denosteorel 60 mg Injection 1 ml cause skin infections?

Denosteorel 60 mg Injection 1 ml might cause skin infections. Consult your doctor immediately if you notice symptoms such as swollen skin, redness, cellulitis (hot and tender skin), commonly in the lower leg with feverish symptoms.