Nemclis Injection is a combination of two drugs, namely: Cilastatin (dehydropeptidase inhibitor) and Imipenem (antibacterial). Nemclis Injection is used to treat severe bacterial infections of the lungs, heart, bladder, skin, kidneys, bones, joints, blood, stomach, and female reproductive organs. Nemclis Injection may also be used in the management of patients with low white blood cell count who have a fever, which is suspected to be due to bacterial infection. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Nemclis Injection helps to treat bacterial infections. Imipenem is a broad-spectrum antibiotic that is effective against a wide range of aerobic and anaerobic bacteria.

FAQs

How does Nemclis Injection work?

Nemclis Injection is a combination of two drugs, namely: Cilastatin and Imipenem. Cilastatin inhibits the dehydropeptidase enzyme, which causes the breakdown of Imipenem, thereby helps imipenem to stay active for a longer duration. Imipenem prevents the formation of the bacterial protective covering, which is necessary for the survival of the bacteria. Together, Nemclis Injection helps to treat bacterial infections.

Does Nemclis Injection cause diarrhoea?

Diarrhoea might be a side-effect of Nemclis Injection. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, consult your doctor. Do not take anti-diarrheal medicine on your own.

Can I take Probenecid with Nemclis Injection?

Concomitant administration of Probenecid (used to treat gout and hyperuricemia) along with Nemclis Injection is not recommended as it might result in an increase of plasma levels and half-life of Imipenem.

Is it safe to take Ganciclovir along with Nemclis Injection?

Ganciclovir (anti-viral) should not be co-administered along with Nemclis Injection unless benefits outweigh the risks as generalised seizures have been reported when taken together.

Does Nemclis Injection cause discolouration of urine?

Nemclis Injection may cause changes in urine colour and amount of urine. Do not worry and consult your doctor if you have any concerns regarding this.

Does Nemclis Injection cause thrush?

Nemclis Injection may rarely cause thrush or candidiasis, which is a fungal infection occurring due to the overgrowth of yeast-like fungus in the mouth or throat. Regularly rinse your mouth with water to prevent the growth of fungus.