5 Flucel 250 Injection 5 ml

Written By Urvashi Bharti , MBBS

Reviewed By Hari Kumar , MBBS

MRP ₹10.5

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Whats That

About 5 Flucel 250 Injection 5 ml

5 Flucel 250 Injection 5 ml belongs to a group of anti-cancer medicines called 'antimetabolites' used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. Cancer is a disease in which cells divide uncontrollably. Cancer can be localized (benign) or spread to the whole body (metastasized).

5 Flucel 250 Injection 5 ml contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

In some cases, 5 Flucel 250 Injection 5 ml may cause nausea, vomiting, weakness, loss of appetite, increased risk of infection, hair loss, diarrhoea, decreased blood cells, and mouth ulcers. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Inform your doctor if you have a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency, heart problems, bone marrow depression, kidney disease, liver disease, or if you are on treatment with chemotherapy or radiation. Avoid taking 5 Flucel 250 Injection 5 ml if you are pregnant or breastfeeding. Both women and men on treatment with 5 Flucel 250 Injection 5 ml should use birth control to avoid pregnancy.

Uses of 5 Flucel 250 Injection 5 ml

Breast, colon, rectum, pancreatic and stomach/gastric cancer

Directions for Use

It will be administered by a healthcare professional. Do not self-administer.

Medicinal Benefits

5 Flucel 250 Injection 5 ml belongs to a group of anti-cancer medicines called 'antimetabolites' used to treat breast, colon, rectum, pancreatic and stomach/gastric cancer. 5 Flucel 250 Injection 5 ml contains 'Fluorouracil' that works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This prevents the cancer cells from multiplying and growing and eventually kills them.

Storage

Keep 5 Flucel 250 Injection 5 ml out of the sight and reach of children.

Side effects of 5 Flucel 250 Injection 5 ml

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Loose And Watery Stools

Here are the precise steps to cope with diarrhoea caused by medication usage:

Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Inflammation Of Mucous Membranes

If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
Practice good hygiene, such as washing your hands regularly, to prevent infection.
Drink plenty of water to keep your mucous membranes hydrated and promote healing.
Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
Follow a soft food diet to reduce discomfort and promote healing.

Decreased Production Of Blood Cells

Eat well-cooked food to minimize infection risk.
Practice good hand hygiene to prevent infections.
Avoid crowds and people with illnesses to reduce exposure.
Wear a mask when necessary to lower infection risk.
Rest adequately to support your body's healing process.
Stay hydrated by drinking plenty of water.
Regularly monitor blood cell counts for changes.
Seek immediate medical help if symptoms like fever, chills, or fatigue occur.
Consult your doctor right away if concerning symptoms arise.
Follow your doctor's guidance on managing myelosuppression and infection prevention.

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Sun Allergy

Drug Warnings

Inform your doctor if you have any infection, a metabolic disorder called DPD (dihydropyrimidine dehydrogenase) deficiency, heart problems, bone marrow depression, kidney disease, liver disease, or if you are on treatment with chemotherapy or radiation. Consult your doctor if you are pregnant because 5 Flucel 250 Injection 5 ml can cause harmful effects on the unborn baby. Women and men using 5 Flucel 250 Injection 5 ml should use birth control to avoid pregnancy. The use of 5 Flucel 250 Injection 5 ml by either parent may result in congenital disabilities. 5 Flucel 250 Injection 5 ml should be used with caution in elderly patients. If you have had leukaemia (blood cancer) and are in remission, do not take live vaccines for three months after your last chemotherapy.

Drug-Drug Interactions

FluorouracilTofacitinib

Severe

FluorouracilWarfarin

Severe

Drug-Drug Interactions

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FluorouracilTofacitinib

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Using tofacitinib together with 5 Flucel 250 Injection 5 ml may increase the risk of serious infections.

How to manage the interaction:
Although there is a interaction between tofacitinib and 5 Flucel 250 Injection 5 ml but can be taken if advised by a doctor. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.

FluorouracilWarfarin

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Taking Warfarin together with 5 Flucel 250 Injection 5 ml may increase the risk of bleeding.

How to manage the interaction:
Although taking Warfarin and 5 Flucel 250 Injection 5 ml together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor immediately if you experience symptoms such as unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Do not stop using any medications without consulting a doctor.

FluorouracilFolic acid

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Coadministration of Folic acid and 5 Flucel 250 Injection 5 ml may increase the effects of 5 Flucel 250 Injection 5 ml and increase the risk of serious side effects such as bleeding problems, anaemia (lack of blood), infections, and nerve damage.

How to manage the interaction:
Although there is a possible interaction between Folic acid and 5 Flucel 250 Injection 5 ml, you can take these medicines together if prescribed by your doctor. However, if you experience diarrhoea, paleness of skin, severe nausea and vomiting, over-tiredness, dizziness, fainting, blood in the stools, unusual bleeding or bruising, fever, chills, body pains, flu-like symptoms, skin reactions, mouth ulcers or sores, and/or numbness, burning or tingling in your hands and feet, contact your doctor.

FluorouracilClozapine

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Co-administration of 5 Flucel 250 Injection 5 ml with Clozapine can increase the risk of neutropenia (low levels of neutrophils in blood).

How to manage the interaction:
There may be a possibility of interaction between 5 Flucel 250 Injection 5 ml and Clozapine, but it can be taken if prescribed by a doctor. If you experience any symptoms such as infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain or burning during urination, it is important to contact a doctor right away. Do not stop using any medications without a doctor's advice.

FluorouracilInfliximab

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Using Infliximab together with 5 Flucel 250 Injection 5 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab together with 5 Flucel 250 Injection 5 ml together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

FluorouracilCladribine

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Combining Cladribine with 5 Flucel 250 Injection 5 ml can increase the risk of side effects.

How to manage the interaction:
Taking Cladribine with 5 Flucel 250 Injection 5 ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.

FluorouracilMitomycin

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Taking 5 Flucel 250 Injection 5 ml with mitomycin has been associated with a condition known as hemolytic uremic syndrome (HUS) and using it with 5 Flucel 250 Injection 5 ml may increase that risk.

How to manage the interaction:
Although taking Mitomycin and 5 Flucel 250 Injection 5 ml together can cause an interaction, it can be taken if your doctor has suggested it. Do not discontinue any medications without first consulting a doctor.

FluorouracilThalidomide

Severe

How does the drug interact with 5 Flucel 250 Injection 5 ml:
Taking thalidomide together with 5 Flucel 250 Injection 5 ml may increase the risk of blood clots and that may lead to serious complications.

How to manage the interaction:
Although taking thalidomide and 5 Flucel 250 Injection 5 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy diet and exercise regularly to maintain proper weight.
Avoid smoking and alcohol consumption.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
Avoid fast food, fried food, processed meats, refined carbs and added sugars.
Get optimal sleep, and rest well.

Side Effects of 5 Flucel 250 Injection 5 ml

Nausea
Vomiting
Weakness
Loss of appetite
Increased risk of infection
Hair loss
Diarrhoea
Decreased blood cells
Mouth ulcer

Habit Forming

No

Therapeutic Class

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Author Details

Written By

Urvashi Bharti

MBBS

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:35 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does 5 Flucel 250 Injection 5 ml work?

5 Flucel 250 Injection 5 ml works by interfering with the growth of genetic material (DNA and RNA) of the cancer cells. This slows the growth of cancer cells and eventually kills them.

Does 5 Flucel 250 Injection 5 ml cause hair loss?

Yes, 5 Flucel 250 Injection 5 ml affects the hair by making it thin, which further causes hair loss. However, it is not very common. Hair reduction possibly happens due to the estrogen-lowering effect of 5 Flucel 250 Injection 5 ml. These effects are not long-lasting and may return after some time. If it matters to you, then consult your doctor for further advice.

Does 5 Flucel 250 Injection 5 ml affect laboratory test results?

Yes, 5 Flucel 250 Injection 5 ml may change the results of blood tests and other laboratory tests. Inform the person doing the tests that you are taking 5 Flucel 250 Injection 5 ml.

Does 5 Flucel 250 Injection 5 ml affects fertility?

$nanme might affect fertility (ability to have children) in both men and women. You may not be able to become pregnant or father a child after treatment with 5 Flucel 250 Injection 5 ml. However, it is essential to talk to your doctor before starting treatment with 5 Flucel 250 Injection 5 ml if you think you may want to have a baby in the future.

Drug-Drug Interactions Checker List

METHOTREXATE
CISPLATIN
CYTARABINE
MITOMYCIN
TAMOXIFEN
METRONIDAZOLE
ALLOPURINOL
CIMETIDINE
WARFARIN
INTERFERON ALFA
PHENYTOIN
RUBELLA (LIVE ATTENUATED)
MUMPS (LIVE ATTENUATED)
MEASLES (LIVE ATTENUATED)
BACILLUS CALMETTE-GUERIN(BCG) VACCINE
SHINGLES VACCINE
CALCIUM LEUCOVORIN
BRIVUDINE
SORIVUDINE

Special Advise

Your doctor may suggest routine blood tests to monitor your liver function, electrolyte levels, and blood cell count.
Consult a doctor immediately if you notice any signs of infection, fever, diarrhoea, chills, etc.
Women of childbearing potential and men with partners of childbearing potential must use an effective method of contraception while on treatment with 5 Flucel 250 Injection 5 ml and for at least three months afterwards. Please consult your doctor for any concerns regarding this.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells stimulated by a female sex hormone called oestrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and the fatty tissue or the fibrous connective tissue within the breast. The tumour cells invade other healthy breast cells and travel to lymph nodes, a primary pathway for the cancer cells to move to other body parts. Symptoms of breast cancer include a lump in the breast or tissue thickening, which feels different than the normal surrounding tissues, breast pain, redness, swelling, and nipple discharge other than breast milk.

Stomach Cancer (gastric cancer): It is a type of cancer that develops from the stomach lining. Risk factors may include smoking, a highly processed or salty diet, and severe bacterial infection of H. pylori. Symptoms of stomach cancer include feeling bloated after eating, feeling full after eating small amounts of food, nausea, heartburn or indigestion.