ABCIXIREL 10MG INJECTION 5ML

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹8910

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₹1336.5 Cashback (15%)

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Whats That

About ABCIXIREL 10MG INJECTION

ABCIXIREL 10MG INJECTION belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. ABCIXIREL 10MG INJECTION is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.

ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).

ABCIXIREL 10MG INJECTION may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer ABCIXIREL 10MG INJECTION. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

ABCIXIREL 10MG INJECTION should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.

Uses of ABCIXIREL 10MG INJECTION

Myocardial infarction (heart attack)

Directions for Use

A trained healthcare professional will administer ABCIXIREL 10MG INJECTION. Hence, do not self-administer.

Medicinal Benefits

ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.

Storage

Keep ABCIXIREL 10MG INJECTION out of the sight and reach of children.

Side effects of Abcixirel 10mg Injection 5ml

Bleeding

Low Blood Pressure

Managing Low Blood Pressure Triggered by Medication: Expert Advice:

If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
Take regular breaks to sit or lie down if you need to stand for long periods.
When lying down, elevate your head with extra pillows to help improve blood flow.
Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Back Pain

Managing back pain as a side effect of medication requires a combination of self-care techniques, lifestyle modifications, and medical interventions. Here are the steps:

Talk to your doctor about your back pain and potential medication substitutes or dose changes.
Try yoga or Pilates and other mild stretching exercises to increase flexibility and strengthen your back muscles.
To lessen the tension on your back, sit and stand upright and maintain proper posture.
To alleviate discomfort and minimize inflammation, apply heat or cold packs to the afflicted area.
Under your doctor's supervision, think about taking over-the-counter painkillers like acetaminophen or ibuprofen.
Make ergonomic adjustments to your workspace and daily activities to reduce strain on your back.
To handle tension that could make back pain worse, try stress-reduction methods like deep breathing or meditation.
Use pillows and a supportive mattress to keep your spine in the right posture as you sleep.
Back discomfort can worsen by bending, twisting, and heavy lifting.
Speak with a physical therapist to create a customized training regimen to increase back strength and flexibility.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Chest Pain

Chest pain may last for a while and needs immediate medical attention as it is a significant health issue to be attended to.
Take rest and refrain from doing physical activity for a while, and restart after a few days.
Try applying an ice pack to the strained area for at least 20 minutes thrice a day. Ice pack thus helps reduce inflammation.
Sit upright and maintain proper posture if there is persistent chest pain. • Use extra pillows to elevate your position and prop your chest up while sleeping.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

Do not receive ABCIXIREL 10MG INJECTION if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.

Drug-Drug Interactions

AbciximabRivaroxaban

Severe

AbciximabApixaban

Severe

Drug-Drug Interactions

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AbciximabRivaroxaban

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Co-administration of Abcixirel 10mg Injection 5ml and Rivaroxaban can increase the risk of unusual bleeding.

How to manage the interaction:
Co-administration of Abcixirel 10mg Injection 5ml and Rivaroxaban can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like unusual bleeding or bruising, dizziness, lightheadedness, red or black, dark stools, coughing or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

AbciximabApixaban

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Coadministration of Abcixirel 10mg Injection 5ml and Apixaban co-administration may raise the risk of bleeding.

How to manage the interaction:
Even though combining Abcixirel 10mg Injection 5ml and Apixaban may cause an interaction, it is still possible to take it if your doctor advises you to. Consult a doctor if you experience symptoms like blood in your urine or stool (or a black stool), severe bruising, prolonged nosebleeds, feeling dizzy or lightheaded, weakness or severe headache, vomiting blood or coughing up blood, heavy menstrual bleeding (in women), difficulty breathing, or chest pain. Without consulting a doctor, never stop taking any medications.

AbciximabPrasugrel

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Co-administration of Abcixirel 10mg Injection 5ml with Prasugrel can increase the risk of bleeding.

How to manage the interaction:
Taking Prasugrel with Abcixirel 10mg Injection 5ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of the following symptoms: unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult the doctor. Do not stop using any medications without talking to a doctor.

AbciximabFondaparinux

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Taking Abcixirel 10mg Injection 5ml with fondaparinux can increase the risk of bleeding.

How to manage the interaction:
Although there is an interaction between Abcixirel 10mg Injection 5ml and Fondaparinux, it can be taken if prescribed by a doctor. However, if you experience bleeding, bruising, feeling dizzy or lightheaded, dark or black stools, severe headache, weakness, bleeding, or vomiting contact a doctor immediately. Do not stop using any medications without a doctor's advice.

AbciximabDalteparin

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
The combined use of Abcixirel 10mg Injection 5ml with Dalteparin can increase the risk of bleeding.

How to manage the interaction:
Taking Abcixirel 10mg Injection 5ml with Dalteparin together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, contact a doctor immediately if you experience any symptoms such as bleeding, severe bleeding, bruising, dark or black stools, severe headache, weakness, bleeding, or vomiting. Do not discontinue any medications without consulting a doctor.

AbciximabDasatinib

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Using Dasatinib together with Abcixirel 10mg Injection 5ml may increase the risk of bleeding.

How to manage the interaction:
Taking Abcixirel 10mg Injection 5ml with Dasatinib together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs, it's important to contact a doctor right away - bruising, feeling dizzy or lightheaded, dark stools, intense headaches. Do not stop using any medications without talking to a doctor.

AbciximabDeferasirox

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Using deferasirox together with Abcixirel 10mg Injection 5ml may increase the risk of gastrointestinal ulcers.

How to manage the interaction:
Co-administration of Abcixirel 10mg Injection 5ml with Deferasirox can possibly result in an interaction, but it can be taken if your doctor has advised it. This risk is higher in older people with certain blood disorders or low platelet counts.If you have symptoms like stomach pain, bloating, dizziness, or black stools, it's important to consult a doctor. Do not stop using any medications without a doctor's advice.

AbciximabEnoxaparin

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Combining Abcixirel 10mg Injection 5ml with Enoxaparin can increase the risk of bleeding.

How to manage the interaction:
Although taking Abcixirel 10mg Injection 5ml and Enoxaparin together can cause an interaction, it can be taken if your doctor has suggested it. If you notice any of these symptoms like feeling dizzy or lightheaded, dark or tar-like stools, a severe headache, feeling weak, bruising, bleeding, or vomiting, it's important to contact your doctor right away. Do not stop using any medications without first talking to a doctor.

AbciximabDabigatran etexilate

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Taking Dabigatran etexilate with Abcixirel 10mg Injection 5ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Taking Dabigatran etexilate with Abcixirel 10mg Injection 5ml together can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, consult the doctor. Do not stop using any medications without a doctor's advice.

AbciximabWarfarin

Severe

How does the drug interact with Abcixirel 10mg Injection 5ml:
Coadministration of Warfarin with Abcixirel 10mg Injection 5ml can increase the effect of Warfarin.

How to manage the interaction:
Although there is a possible interaction between Warfarin and Abcixirel 10mg Injection 5ml, you can take these medicines together if prescribed by a doctor. However, if you experience unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, contact a doctor. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a diet rich in whole grains, vegetables, fruits, skinless poultry, fish, eggs, and low-fat dairy products.
Avoid smoking and alcohol consumption.
Maintain a healthy weight with proper diet and exercise.
Managing stress with meditation, yoga, and massage.
Avoid eating fried food, fast food, boxed food, canned food, and processed frozen meals.

Side Effects of ABCIXIREL 10MG INJECTION

Bleeding
Nausea
Headache
Abdominal pain
Hypotension
Vomiting
Dizziness
Back pain
Pain at the site of injection

Habit Forming

No

Therapeutic Class

ANTICOAGULANT/ANTITHROMBOTIC

Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does ABCIXIREL 10MG INJECTION work?

ABCIXIREL 10MG INJECTION contains Abciximab, which works by blocking the activity of glycoprotein IIb/IIIa receptor and thereby prevents platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.

Does ABCIXIREL 10MG INJECTION increase the risk of bleeding?

ABCIXIREL 10MG INJECTION is usually administered along with heparin and aspirin, so it might increase the risk of bleeding. Inform the doctor immediately if you notice excess bleeding.

Does ABCIXIREL 10MG INJECTION cause anaemia?

ABCIXIREL 10MG INJECTION may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.

Drug-Drug Interactions Checker List

ASPIRIN
IBUPROFEN
CELECOXIB
CLOPIDOGREL
ENOXAPARIN
CAPTOPRIL
ENALAPRIL
NIFEDIPINE
CILNIDIPINE
ATENOLOL
SOTALOL
WARFARIN
HEPARIN

Special Advise

Before administration of ABCIXIREL 10MG INJECTION, a blood test for platelet count, prothrombin time, ACT and APTT should be done to check for any hemostatic abnormalities.
As ABCIXIREL 10MG INJECTION will be administered along with heparin and aspirin, it is always important to check the patient for any bleeding conditions.

Disease/Condition Glossary

Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).

Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.