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About ABCIXIREL 10MG INJECTION
ABCIXIREL 10MG INJECTION belongs to the group of medicines called 'antiplatelet agents' used to prevent the formation of blood clots, thereby reducing the chance of Myocardial infarction. ABCIXIREL 10MG INJECTION is used as an adjunct during percutaneous coronary intervention (PCI) procedure in patients with unstable angina not responding to conventional medical therapy when PCI procedure is planned within 24 hours.
ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST).
ABCIXIREL 10MG INJECTION may cause certain side effects such as bleeding, nausea, headache, abdominal pain, hypotension, vomiting, dizziness, back pain, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare professional will administer ABCIXIREL 10MG INJECTION. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.
ABCIXIREL 10MG INJECTION should be avoided if you are allergic to it. It is contraindicated in patients who have active internal bleeding, thrombocytopenia, severe uncontrolled hypertension, had recent major surgery or trauma, a history of cerebrovascular accident within the last two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, used dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION, have/had a recent severe injury or surgery due to risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.
Uses of ABCIXIREL 10MG INJECTION
Directions for Use
Medicinal Benefits
ABCIXIREL 10MG INJECTION contains Abciximab, which belongs to the monoclonal anti-glycoprotein IIb/IIIa receptor antibodies class. It works by blocking the glycoprotein IIb/IIIa receptor's activity, thereby preventing platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation. ABCIXIREL 10MG INJECTION results in reducing the risk of cardiovascular events like myocardial infarction (heart attack), repeat coronary revascularization, and stent thrombosis (ST). This medicine is always administered along with aspirin and heparin.
Storage
Drug Warnings
Do not receive ABCIXIREL 10MG INJECTION if you are allergic to it. This medicine is contraindicated in patients having active internal bleeding, thrombocytopenia, recent major surgery or trauma, severe uncontrolled hypertension, history of cerebrovascular accident within two years, or recent gastrointestinal or genitourinary bleeding, intracranial neoplasm, aneurysm, use of dextran before PCI procedure, and history of vasculitis as it can cause serious adverse effects. ABCIXIREL 10MG INJECTION is administered along with aspirin and heparin. Hence, close monitoring of patients is needed for any bleeding conditions. Talk to your doctor before receiving ABCIXIREL 10MG INJECTION if you have/had a recent severe injury or surgery due to the risk of severe bleeding problems. If you are pregnant or breastfeeding, inform your doctor before receiving this medicine. ABCIXIREL 10MG INJECTION is not recommended for children below 12 years of age as efficacy and safety have not been established.
Drug-Drug Interactions
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Side Effects of ABCIXIREL 10MG INJECTION
Habit Forming
Therapeutic Class
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Drug-Diseases Interactions
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ABCIXIREL 10MG INJECTION contains Abciximab, which works by blocking the activity of glycoprotein IIb/IIIa receptor and thereby prevents platelet aggregation. This causes inhibition of fibrinogen binding, reducing the chance of blood clot formation.
ABCIXIREL 10MG INJECTION is usually administered along with heparin and aspirin, so it might increase the risk of bleeding. Inform the doctor immediately if you notice excess bleeding.
ABCIXIREL 10MG INJECTION may cause anaemia (low haemoglobin and low red blood cell count). So, it would be best to include iron-rich food in your diet to prevent anaemia.
Drug-Drug Interactions Checker List
Special Advise
Disease/Condition Glossary
Blood clot: Platelets are small cell particles that circulate in the blood. When the blood vessel is damaged or cut, the platelets clump together and lead to the formation of a clot. Thus, it prevents bleeding. The formation of clots in arteries can cut off the blood supply, leading to heart attack, stroke or death. Clot formation in the arteries that supply blood to the heart may cause reduced blood flow, leading to unstable angina (chest pain).
Myocardial infarction: Myocardial infarction, also known as a heart attack or stroke, could occur due to the lack of blood and oxygen supply in the heart. Symptoms include chest pain, upper body pain, sweating, weakness, trouble breathing, lightheadedness and nausea.
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Alcohol
Unsafe
Alcohol intake might increase the risk of stomach or intestine bleeding. Hence, avoid alcohol consumption. Consult your doctor for more information.
Pregnancy
Caution
It is also unknown whether ABCIXIREL 10MG INJECTION can cause fetal damage or alter reproductive capacity when given to a pregnant woman. Your doctor may prescribe this medicine only if clearly needed.
Breast Feeding
Caution
Limited data are available on the effect of ABCIXIREL 10MG INJECTION on breastfeeding. Hence, if you are a nursing mother, inform your doctor before receiving ABCIXIREL 10MG INJECTION. Your doctor may prescribe this medicine if the benefits outweigh the risks.
Driving
Not applicable
ABCIXIREL 10MG INJECTION is used in PCI procedures in a hospital setting. Driving is not recommended.
Liver
Caution
If you have liver problems, inform your doctor beforehand.
Kidney
Unsafe
If you have kidney impairment, inform your doctor beforehand.
Children
Unsafe
ABCIXIREL 10MG INJECTION is not recommended for use in children below 12 years of age, as efficacy and safety have not been established.