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  3. ABD-400 Tablet 10's

ABD-400 Tablet 10's, Pack of 10 TabletS
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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ALBENDAZOLE-400MG

Manufacturer/Marketer :

Intas Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About ABD-400 Tablet

 ABD-400 Tablet belongs to a group of antiparasitic drugs called 'anthelmintic' used to treat parasites worm infections like neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). Additionally, ABD-400 Tablet is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. 

ABD-400 Tablet contains ‘Albendazole’, which works by inhibiting tubulin polymerisation. This causes metabolic disruption and energy depletion in the parasite, which leads to its immobilisation. Thereby, ABD-400 Tablet kills the susceptible helminth and treats the infection. 

Take ABD-400 Tablet as prescribed. You are advised to take ABD-400 Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. You may experience certain common side effects, such as stomach pain, nausea, vomiting, headache, and dizziness in some cases. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

ABD-400 Tablet might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or colds. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking ABD-400 Tablet . Do not take ABD-400 Tablet if you are pregnant or planning for pregnancy as it may cause foetal harm. Do not breastfeed during and for a minimum of 5 days after treatment with ABD-400 Tablet . ABD-400 Tablet may cause dizziness, so be cautious while driving. ABD-400 Tablet can be given to children if prescribed by the doctor. Keep your doctor informed about your health condition and medicines to rule out any side effects.

Uses of ABD-400 Tablet

Parasitic worm infections

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not chew or crush the tablet/capsule.Syrup/Suspension/Drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use.Chewable tablet: Chew the tablet completely and swallow. Do not swallow it as a whole.

Medicinal Benefits

ABD-400 Tablet belongs to a group of medicines called anthelmintic used to treat worm infections such as neurocysticercosis (infection caused by pork tapeworm) and cystic hydatid disease (infection caused by dog tapeworm). ABD-400 Tablet is also used to treat infections caused by roundworms, hookworms, threadworms, whipworms, pinworms, flukes, and other parasites. ABD-400 Tablet is a broad-spectrum anthelmintic drug which is highly effective against a wide range of intestinal helminths, including cestodes, nematodes, and trematodes. It is also effective against tissue helminth infections like cutaneous larva migrans (parasitic skin infections). ABD-400 Tablet exhibits ovicidal, larvicidal and vermicidal activity. ABD-400 Tablet inhibits tubulin polymerisation, which causes metabolic disruption and energy depletion in the parasite. This leads to the immobilisation of the parasite. Thereby, ABD-400 Tablet kills the susceptible helminth and treats the infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of ABD-400 Tablet
  • High levels of liver enzymes need immediate medical attention.
  • Watch your diet and consume low-fat foods, like green leafy vegetables, fish, whole grains, nuts, etc.
  • Regularly do strengthening exercises to control your cholesterol levels.
  • Avoid drinking alcohol as it can affect your liver.
  • Focus on losing weight as it can help control cholesterol and maintain liver enzymes.
  • Practice yoga and meditation to improve liver functioning and overall health.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Your doctor can provide you with some medications to reduce the production of cerebrospinal fluid and subsequently lower intracranial pressure.
  • Tell your doctor immediately when you feel more severe symptoms like changes in vision, confusion, or even seizure.
  • Take fruits, vegetables, lean proteins, and whole grains to maintain a balanced diet.
  • Reduce your intake of sodium for better fluid retention and lower blood pressure.
  • Keep yourself fit with a healthy weight to decrease intracranial pressure.
  • Yoga, meditation, and deep breathing will help reduce your stress levels.
  • Regularly visiting the doctor helps monitor progress, health of eyes, and intracranial pressure.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Use suitable comb to detangle hair gently, especially when wet.
  • Avoid harsh chemicals like strong dyes and relaxers.
  • Limit heat styling tools like curling irons and flat irons.
  • Massaging your scalp regularly helps to stimulate blood circulation.
  • Avoid tight hairstyles like ponytails, braids, or buns that can pull on the hair.
  • Change hairstyles frequently to avoid putting constant tension on the same hair follicles.
  • Ensure adequate intake of iron, zinc, vitamin B12, and biotin, which are crucial for healthy hair growth.
  • Take balanced diet with plenty of fruits, vegetables, and whole grains.
  • Manage stress levels by practicing yoga and meditation.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
  • Get sufficient sleep and manage stress which helps in improving white blood cell count.
  • Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
  • Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Drug Warnings

Do not take ABD-400 Tablet if you are allergic to any of its contents. ABD-400 Tablet may cause bone marrow suppression, aplastic anaemia, and agranulocytosis. Inform your doctor if you have/had liver disease; if you have any surgery, including dental surgery. Consult your doctor immediately if you experience seizures, vomiting, headache, extreme tiredness, or behaviour changes while taking ABD-400 Tablet . Regular blood cell count and liver function monitoring is advised during treatment with ABD-400 Tablet . ABD-400 Tablet might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or cold. Consult your doctor if you notice unusual bleeding or bruising, as you may bleed or bruise easily while taking ABD-400 Tablet . Do not take ABD-400 Tablet if you are pregnant or planning for pregnancy as it may cause foetal harm. Do not breastfeed during and for minimum of 5 days after treatment with ABD-400 Tablet . ABD-400 Tablet may cause dizziness, so be cautious while driving. ABD-400 Tablet can be given to children if prescribed by the doctor.

Drug-Drug Interactions

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AlbendazoleClozapine
Severe
AlbendazoleCladribine
Severe

Drug-Drug Interactions

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AlbendazoleClozapine
Severe
How does the drug interact with ABD-400 Tablet:
Co-administration of ABD-400 Tablet with Clozapine may increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between ABD-400 Tablet and Clozapine, you can take these medicines together if advised by your doctor. However, if you develop symptoms such as chills, diarrhea, fever, sore throat, shortness of breath, muscle pains, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination, contact a doctor immediately. Do not discontinue the medication without consulting a doctor.
AlbendazoleCladribine
Severe
How does the drug interact with ABD-400 Tablet:
Taking ABD-400 Tablet with Cladribine can increase the risk of side effects.

How to manage the interaction:
Although taking Cladribine and ABD-400 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you have any of these symptoms, contact a doctor right away. These symptoms include fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, and pain or burning when you urinate. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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ALBENDAZOLE-400MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ALBENDAZOLE-400MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit and Grapefruit juice can increase the absorption of ABD-400 Tablet. Avoid consuming Grapefruit and Grapefruit juice while being treated with ABD-400 Tablet.

Diet & Lifestyle Advise

  • Regularly wash your hands with soap and water, especially after using the toilet and while eating.
  • Avoid eating raw fish and meat.
  • Thoroughly cook meat before eating.
  • Wash all fruits and vegetables properly before consuming.
  • Wash or reheat food that has been around for a long time.
  • Avoid contact with soil that may be contaminated with faeces.
  • Avoid foods that have been kept open in the markets as they can be contaminated.
  • Drink boiled and purified water.

Habit Forming

No

Therapeutic Class

ANTIHELMINTICS

ABD-400 Tablet Substitute

Substitutes safety advice

  • Aquris Albenzole Tablet 1's

    by Others

    ₹9.00per tablet

  • Zentel Tablet 1's

    by Others

    ₹8.10per tablet

  • Albendazole 400 mg Tablet 1's

    by Others

    ₹6.80per tablet

  • Albzoale 400 Chewable Tablet 1's

    by Others

    ₹7.20per tablet

  • Noworm Tablet 1's

    by Others

    ₹8.10per tablet

Product Substitutes

Author Details

Doctor imageDoctor badge

Written By

Santoshini Reddy G

M Pharmacy

Doctor image

Reviewed By

Sunny S

MBBS

Last Updated

Aug 20, 2024 | 12:52 PM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
ALBENDAZOLE-400MGOther diseases of biliary tract
Moderate
ALBENDAZOLE-400MGOther disorders of brain
Moderate

Drug-Diseases Interactions

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ALBENDAZOLE-400MGOther diseases of biliary tract
Moderate
How does the disease interact with ABD-400 Tablet:
ABD-400 Tablet should be administered cautiously in patients with compromised hepatic function.

How to manage the interaction:
ABD-400 Tablet should be used with caution in patients with compromised liver function. Clinical monitoring of liver function is recommended before starting ABD-400 Tablet and at least every two weeks during therapy.
ALBENDAZOLE-400MGOther disorders of brain
Moderate
How does the disease interact with ABD-400 Tablet:
ABD-400 Tablet for neurocysticercosis should be administered cautiously in patients with or predisposition to seizures.

How to manage the interaction:
ABD-400 Tablet should be used with caution in patients with or prone to fits.
ALBENDAZOLE-400MGAcute renal failure
Moderate
How does the disease interact with ABD-400 Tablet:
The pharmacokinetics of ABD-400 Tablet in patients with impaired renal function have not been studied. Caution is advised if used in these patients.

How to manage the interaction:
ABD-400 Tablet should be used with caution in patients with impaired kidney function.

FAQs

ABD-400 Tablet causes metabolic disruption and energy depletion in the parasite, which leads to its immobilisation. Thereby, ABD-400 Tablet kills the susceptible helminth and treats the infection.

For neurocysticercosis, ABD-400 Tablet is usually prescribed for 8-30 days. For cystic hydatid disease, ABD-400 Tablet is usually prescribed for 28 days, followed by a 14 day break, and repeated for a total of 3 cycles.

Do not discontinue ABD-400 Tablet without consulting your doctor. To treat your condition effectually continue taking ABD-400 Tablet for as long as prescribed. Do not be reluctant to speak with your doctor if you feel any difficulty while taking ABD-400 Tablet .

You are recommended to avoid planning for pregnancy while taking ABD-400 Tablet as it may cause foetal harm. A pregnancy test should be done before starting the treatment with ABD-400 Tablet , and women must use effective birth-control while taking ABD-400 Tablet and for at least 1month after cessation of treatment.

Regular monitoring of blood count at the beginning of each cycle therapy and for every 2weeks while taking ABD-400 Tablet is advised for all patients. Treatment with ABD-400 Tablet should be discontinued if a significant decrease in blood cell count is observed.

Treatment with ABD-400 Tablet has been associated with mild to moderate elevations of liver enzymes. These elevations generally return to normal upon discontinuation of ABD-400 Tablet . Liver function tests should be performed before each treatment cycle and for every 2weeks during the treatment. Treatment with ABD-400 Tablet should be discontinued if the liver enzymes exceed twice the upper limit of normal.

ABD-400 Tablet might increase the chances of getting an infection. Maintain proper hygiene and try to stay away from people with infections, flu or cold.

You may bleed or bruise easily while taking ABD-400 Tablet . Be cautious while using sharp objects and try to avoid injuries. Consult your doctor if you notice unusual bleeding or bruising.

Drug-Drug Interactions Checker List

  • DEXAMETHASONE
  • CIMETIDINE
  • THEOPHYLLINE
  • PRAZIQUANTEL

Special Advise

  • Regular monitoring of blood cell count and liver function is advised during treatment with ABD-400 Tablet .
  • ABD-400 Tablet might increase the chances of getting an infection; maintain proper hygiene, and try to stay away from people with infections, flu or cold.
  • Consult your doctor if you notice unusual bleeding or bruising as you may bleed or bruise easily while taking ABD-400 Tablet .
  • ABD-400 Tablet will not treat a viral infection such as the flu or a common cold.

Disease/Condition Glossary

Parasitic worm infections: Parasitic worms are also called intestinal worms or helminths. They live in and feed on the hosts leading to weakness and diseases. Common types of intestinal worms are roundworms and flatworms, such as tapeworms and flukes. Worm infections could occur due to consumption of contaminated water, food or soil, contact with contaminated faeces, poor sanitisation and poor hygiene. Symptoms of worm infections include abdominal pain, diarrhoea, nausea, vomiting, gas, bloating, fatigue, unexplained weight loss, and dysentery (bloody stools).

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