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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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About Accetiz P 100 mg/500 mg/2 mg Tablet

Accetiz P 100 mg/500 mg/2 mg Tablet belongs to the class of medications called 'non-steroidal anti-inflammatory drugs (NSAID)' used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone, joint pain, headache, and period pain. Pain is a symptom triggered by the nervous system, causing uncomfortable sensations in the body. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable.
 
Accetiz P 100 mg/500 mg/2 mg Tablet contains Tizanidine (muscle relaxant), Aceclofenac (pain killer), and Paracetamol (mild analgesic and fever reducer). Tizanidine works on the brain's centres, thereby helping to relieve muscle stiffness and improve muscle movements. Aceclofenac and Paracetamol work by blocking chemical messengers that cause pain and inflammation at the injured or damaged site. Together, Accetiz P 100 mg/500 mg/2 mg Tablet helps in relieving pain due to muscle spasms.
 
You are advised to take Accetiz P 100 mg/500 mg/2 mg Tablet for as long as your doctor has prescribed it for you depending on your medical condition. In some cases, you may experience certain common side-effects such as nausea, vomiting, stomach pain, loss of appetite, heartburn, and diarrhoea. Most of these side-effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Consult your doctor if you are pregnant or breastfeeding. Accetiz P 100 mg/500 mg/2 mg Tablet may cause drowsiness and dizziness, so drive with caution. Accetiz P 100 mg/500 mg/2 mg Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol as it may cause increased drowsiness, dizziness and increased risk of stomach bleeding. Keep your doctor informed about your health condition and medicines to rule out any side-effects/interactions.

Uses of Accetiz P 100 mg/500 mg/2 mg Tablet

Musculoskeletal pain

Directions for Use

Swallow Accetiz P 100 mg/500 mg/2 mg Tablet as a whole with a glass of water; do not chew, or break it.

Medicinal Benefits

Accetiz P 100 mg/500 mg/2 mg Tablet is a combination of three drugs, namely: Tizanidine, Aceclofenac, and Paracetamol. Accetiz P 100 mg/500 mg/2 mg Tablet is used to relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle pain, tooth pain, bone and joint pain, headache, and period pain. Tizanidine is a muscle relaxant which works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol are analgesics which work by blocking the effect of a chemical messenger known as cyclo-oxygenase (COX) enzymes that make other chemical prostaglandins. Prostaglandins are produced at injury sites and cause pain and swelling. By blocking the COX enzymes' effect, lesser prostaglandins are produced, which reduces mild to moderate pain and inflammation at the injured or damaged site. Together, Accetiz P 100 mg/500 mg/2 mg Tablet helps in relieving pain and fever due to muscle spasms.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Accetiz P 100 mg/500 mg/2 mg Tablet

  • Nausea
  • Vomiting
  • Stomach pain
  • Diarrhoea
  • Loss of appetite
  • Heartburn

Drug Warnings

Do not take Accetiz P 100 mg/500 mg/2 mg Tablet if you are allergic to any of its contents; if you have/had severe heart problems, stomach ulcer or perforation, and bleeding problems such as bleeding from the stomach, intestine or brain, bypass surgery, heart attack, blood circulation problems, or inflammation of intestines. Inform your doctor if you have or had high blood pressure, heart problems, high cholesterol, diabetes, asthma, inflammatory bowel disease, liver and kidney problems. Consult your doctor if you are pregnant or breastfeeding. Accetiz P 100 mg/500 mg/2 mg Tablet may cause drowsiness and dizziness, so drive only if you are alert. Accetiz P 100 mg/500 mg/2 mg Tablet is not recommended for children as safety and effectiveness have not been established. Avoid consuming alcohol along with Accetiz P 100 mg/500 mg/2 mg Tablet as it could lead to increased drowsiness and can increase the risk of stomach bleeding. Stop taking Accetiz P 100 mg/500 mg/2 mg Tablet and consult your doctor immediately if you have stomach pain or any signs of bleeding in the intestine or stomach, such as blood in stools. Do not take any other NSAIDs for pain relief along with Accetiz P 100 mg/500 mg/2 mg Tablet unless prescribed. 

Drug-Drug Interactions

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TizanidineFluvoxamine
Critical
TizanidineDronedarone
Critical

Drug-Drug Interactions

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TizanidineFluvoxamine
Critical
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Taking Fluvoxamine with Accetiz P 100 mg/500 mg/2 mg Tablet it can increases the risk of side effects.

How to manage the interaction:
Although Fluvoxamine with Accetiz P 100 mg/500 mg/2 mg Tablet is not recommended, but can be taken together if prescribed by a doctor. However, if you experience drowsiness, dizziness, low blood pressure, slurred speech, confusion, or severe weakness, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
TizanidineDronedarone
Critical
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Coadministration of Accetiz P 100 mg/500 mg/2 mg Tablet with Dronedarone can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Accetiz P 100 mg/500 mg/2 mg Tablet with Dronedarone is generally avoided as it can result in an interaction, it can be taken when prescribed by a doctor. If you experience sudden dizziness, shortness of breath, palpitations, or chest pain, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
TizanidineCiprofloxacin
Critical
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Coadministration of Ciprofloxacin and Accetiz P 100 mg/500 mg/2 mg Tablet together can increase the risk of side effects.

How to manage the interaction:
Using Ciprofloxacin and Accetiz P 100 mg/500 mg/2 mg Tablet together is avoided, as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience drowsiness, weakness, sweating, or palpitations contact the doctor immediately. Do not discontinue any medications without consulting the doctor.
TizanidineSaquinavir
Critical
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Combining Accetiz P 100 mg/500 mg/2 mg Tablet with Saquinavir can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Accetiz P 100 mg/500 mg/2 mg Tablet with Saquinavir is not recommended, as it can result in an interaction, but it can be taken if your doctor has advised it. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhoea or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.
TizanidineZiprasidone
Critical
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Co-administration of Accetiz P 100 mg/500 mg/2 mg Tablet with Ziprasidone can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Accetiz P 100 mg/500 mg/2 mg Tablet with Ziprasidone is not recommended, as it can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor immediately if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting. Do not discontinue any medications without consulting a doctor.
TizanidineCisapride
Critical
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Coadministration of Accetiz P 100 mg/500 mg/2 mg Tablet with Cisapride can increase the risk of irregular heart rhythm.

How to manage the interaction:
Taking Accetiz P 100 mg/500 mg/2 mg Tablet with Cisapride is avoided as it can result in an interaction, it can be taken if your doctor has advised it. Contact your doctor immediately if you experience sudden dizziness, shortness of breath, palpitations, or vomiting. Do not discontinue any medications without consulting your doctor.
AceclofenacAtenolol
Severe
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Co-administration of Atenolol with Accetiz P 100 mg/500 mg/2 mg Tablet could increase the risk of low blood pressure.

How to manage the interaction:
Although there is a possible interaction between Atenolol and Accetiz P 100 mg/500 mg/2 mg Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience excessive sweating, shortness of breath, palpitations, or chest discomfort. Do not discontinue any medications without consulting a doctor.
ParacetamolLeflunomide
Severe
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Co-administration of Accetiz P 100 mg/500 mg/2 mg Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Accetiz P 100 mg/500 mg/2 mg Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolTeriflunomide
Severe
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Co-administration of Teriflunomide with Accetiz P 100 mg/500 mg/2 mg Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Accetiz P 100 mg/500 mg/2 mg Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Accetiz P 100 mg/500 mg/2 mg Tablet:
Co-administration of Accetiz P 100 mg/500 mg/2 mg Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Accetiz P 100 mg/500 mg/2 mg Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Exercising regularly helps in muscle stretching so that they are less likely to spasm, tear and sprain. Mild exercises such as jogging and walking are helpful for muscle stretching.
  • Massages can also be helpful.
  • Avoid freezing and hot temperatures.
  • Avoid wearing tight-fitting clothes, instead, wear loose garments.
  • Rest well, get plenty of sleep.
  • To avoid developing pressure sores, change your position at least every two hours.
  • Hot or cold therapy can help treat muscle spasms. Apply an ice-pack or hot-pack on the muscle for 15-20minutes.
  • Stay hydrated, drink plenty of water.

Habit Forming

No

Therapeutic Class

ANALGESICS

Accetiz P 100 mg/500 mg/2 mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Accetiz P 100 mg/500 mg/2 mg Tablet contains Tizanidine, Aceclofenac, and Paracetamol. Tizanidine is a muscle relaxant which works on the centres of the spinal cord and brain. This helps relieve muscle stiffness and improves muscle movements. Aceclofenac and Paracetamol are analgesics which work by blocking chemical messengers that cause pain and inflammation at the injured or damaged site.

Accetiz P 100 mg/500 mg/2 mg Tablet is used to reduce and relieve pain and inflammation associated with osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis. Arthritis is the tenderness and swelling in the joints.

Diarrhoea might be a side-effect of Accetiz P 100 mg/500 mg/2 mg Tablet. Drink enough fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Accetiz P 100 mg/500 mg/2 mg Tablet should not be taken for longer durations unless prescribed by the doctor. If Accetiz P 100 mg/500 mg/2 mg Tablet has been prescribed for longer durations, regular monitoring of kidney function, liver function, and blood count is advised, particularly in elderly patients.

Dry mouth could be a side-effect of Accetiz P 100 mg/500 mg/2 mg Tablet. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol, drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevents drying of the mouth.

Taking Accetiz P 100 mg/500 mg/2 mg Tablet can elevate symptoms of gastric ulcer and bleeding. So, talk to your doctor before taking Accetiz P 100 mg/500 mg/2 mg Tablet if you have stomach ulcers, gastrointestinal bleeding or other bleeding problems like haemophilia.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • IBUPROFEN
  • CELECOXIB
  • NAPROXEN
  • ETORICOXIB
  • HYDROCODONE
  • CITALOPRAM
  • ESCITALOPRAM
  • DULOXETINE
  • FLUOXETINE
  • FLUVOXAMINE
  • PAROXETINE
  • SERTRALINE
  • LITHIUM
  • DIGOXIN
  • ENALAPRIL
  • LISINOPRIL
  • LOSARTAN
  • CANDESARTAN
  • HYDRALAZINE
  • PROPRANOLOL
  • CIPROFLOXACIN
  • OFLOXACIN
  • LEVOFLOXACIN
  • MOXIFLOXACIN
  • FUROSEMIDE
  • AMILORIDE
  • WARFARIN
  • HEPARIN
  • CLOPIDOGREL
  • METHOTREXATE
  • MIFEPRESTONE
  • HYDROCORTISONE
  • PREDNISOLONE
  • CYCLOSPORINE
  • TACROLIMUS
  • ZIDOVUDINE
  • GLIBENCLAMIDE
  • GLICLAZIDE
  • TOLBUTAMIDE
  • ZOLPIDEM
  • PREGABALIN
  • DIPHENHYDRAMINE
  • CETIRIZINE

Special Advise

  • Stop taking Accetiz P 100 mg/500 mg/2 mg Tablet if you experience stomach discomfort or heartburn, vomiting blood or passing black stools, skin troubles such as rash or itching, wheezing or shortness of breath, or yellowing of your skin or the whites of your eyes. 

Disease/Condition Glossary

Musculoskeletal pain: Musculoskeletal pain affects the bones, muscles, ligaments, tendons, and nerves. It can be acute or chronic, can be localised or widespread. The pain can be mild or severe enough to interfere with your daily routine. Musculoskeletal pain could occur due to arthritis, osteoporosis, fractures, dislocations, problems with the bone structure or injury to the bones, joints, tendons, muscles, and ligaments. Symptoms of musculoskeletal pain include stiffness, swelling, redness, weakness, muscle spasms or twitching, trouble moving the affected area, soreness, cracking or popping sound at the joints.

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