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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Hari Kumar , MBBS
Non returnable*
COD available

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Manufacturer/Marketer

Micro Labs Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Acetamide 250 mg Tablet 10's

Acetamide 250 mg Tablet 10's belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Glaucoma is an eye condition that causes damage to the optic nerve due to abnormally increased pressure in the eye. Epilepsy is a disorder of the nervous system due to disturbed nerve cell activity in the brain. Fluid retention is a condition in which fluids are accumulated in the body tissues.
 
Acetamide 250 mg Tablet 10's contains ‘acetazolamide’, which inhibits carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowers intraocular pressure. Acetamide 250 mg Tablet 10's inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system such as epilepsy. Acetamide 250 mg Tablet 10's reduces the activity of carbonic anhydrase, thereby helps lower fluid retention.
 
You are advised to take Acetamide 250 mg Tablet 10's for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects, such as nausea, vomiting, diarrhoea, headache, and increased urination. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Avoid taking Acetamide 250 mg Tablet 10's if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. Acetamide 250 mg Tablet 10's is not recommended for children as safety and effectiveness have not been established. Acetamide 250 mg Tablet 10's might cause dizziness and drowsiness; so, drive only if you are alert. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Acetamide 250 mg Tablet 10's

Glaucoma, Fluid retention/oedema, Epilepsy/seizures, Mountain sickness.

Directions for Use

Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Acetamide 250 mg Tablet 10's belongs to a group of medicines called carbonic anhydrase inhibitors used to treat glaucoma, oedema (fluid retention), epilepsy, and to treat and prevent altitude/mountain sickness. Acetamide 250 mg Tablet 10's works by inhibiting the carbonic anhydrase enzyme. This inhibitory action decreases the secretion of aqueous humour, thereby lowering intraocular pressure. Acetamide 250 mg Tablet 10's inhibits the carbonic anhydrase enzyme; this helps retard abnormal, excessive discharge from central nervous system neurons, thereby helps treat certain dysfunctions of the central nervous system, such as epilepsy. Acetamide 250 mg Tablet 10's reduces the activity of carbonic anhydrase, thereby helping lower fluid retention. Acetamide 250 mg Tablet 10's may also be used to treat muscle weakness/periodic paralysis and to lower the increased pressure in the areas surrounding the spinal cord and brain.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Acetamide 250 mg Tablet 10's

  • Headache
  • Nausea
  • Vomiting
  • Diarrhoea
  • Increased urination
  • Loss of appetite
  • Dizziness

Drug Warnings

Do not take Acetamide 250 mg Tablet 10's if you are allergic to any of its contents; if you have severe kidney/liver problems, chronic non-congestive angle-closure glaucoma, Addison’s disease, if you have low sodium and/or potassium levels or high chlorine levels. Inform your doctor if you have lung problems, kidney stones, electrolyte imbalance, adrenal gland problems, diabetes, or heart problems. Avoid taking Acetamide 250 mg Tablet 10's if you are pregnant, think you are pregnant or planning for pregnancy. Consult your doctor if you are breastfeeding. Acetamide 250 mg Tablet 10's is not recommended for children as safety and effectiveness have not been established. Acetamide 250 mg Tablet 10's might cause dizziness and drowsiness; so, drive only if you are alert. Acetamide 250 mg Tablet 10's might make your skin sensitive to sunlight; therefore, wear protective clothing and sunscreen whilst going out.

Drug-Drug Interactions

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AcetazolamideCisapride
Critical
AcetazolamideDroperidol
Severe

Drug-Drug Interactions

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AcetazolamideCisapride
Critical
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Cisapride with Acetamide 250 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Acetamide 250 mg Tablet with Cisapride lead to an interaction, please consult a doctor before taking it. Consult a doctor immediately if you experience any symptoms such as dizziness, lightheadedness, fainting, or fast or pounding heartbeats. Do not discontinue the medications without consulting a doctor.
AcetazolamideDroperidol
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Droperidol can enhance the effects of Acetamide 250 mg Tablet can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although there is a possible interaction between Acetamide 250 mg Tablet and Droperidol, you can take these medicines together if prescribed by a doctor. If you have any of these symptoms, it's important to contact a doctor right away: dizziness or lightheadedness, fainting, difficulty breathing, heart palpitations, weakness, feeling sleepy or confused, muscle pain, or feeling nauseous or vomiting. Do not stop using any medications without talking to a doctor.
AcetazolamideMethenamine
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Acetamide 250 mg Tablet may reduce the effectiveness of Methenamine.

How to manage the interaction:
Although there is a possible interaction between Acetamide 250 mg Tablet and Methenamine, you can take these medicines together if prescribed by a doctor. However, frequent urine pH testing may be recommended. Do not discontinue the medication without consulting a doctor.
AcetazolamideDronedarone
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Acetamide 250 mg Tablet with Dronedarone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction between Acetamide 250 mg Tablet and Dronedarone, you can take these medicines together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, or fast or pounding heartbeats during treatment with Dronedarone, contact a doctor immediately. Also, inform your doctor if you experience signs of electrolyte disturbance such as weakness, tiredness, drowsiness, confusion, muscle pain, cramps, nausea, or vomiting. Do not discontinue the medication without consulting a doctor.
AcetazolamideTopiramate
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Acetamide 250 mg Tablet with Topiramate may increase the risk of metabolic acidosis (elevated levels of acid in the blood) and kidney stone formation.

How to manage the interaction:
Although there is a possible interaction between Acetamide 250 mg Tablet and Topiramate, you can take these medicines together if prescribed by a doctor. If you experience symptoms of metabolic acidosis such as tiredness, loss of appetite, irregular heartbeat, trouble thinking clearly, and rapid breathing, contact a doctor immediately. Also, if you experience signs or symptoms of kidney stones, such as sudden back pain, abdominal pain, and blood in the urine, or if you have decreased sweating or a fever, contact your doctor immediately. Do not stop using any medications without consulting a doctor.
AcetazolamideZiprasidone
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Acetamide 250 mg Tablet with Ziprasidone may increase the risk of irregular heart rhythm.

How to manage the interaction:
Although there is an interaction between Acetamide 250 mg Tablet and Ziprasidone, they can be taken together if prescribed by a doctor. If you develop sudden dizziness, lightheadedness, fainting, contact a doctor immediately. Do not discontinue any medication without talking to a doctor.
AcetazolamideZonisamide
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Acetamide 250 mg Tablet with Zonisamide may increase the risk or severity of metabolic acidosis (elevated levels of acid in the blood) and kidney stones.

How to manage the interaction:
Although there is a possible interaction between Acetamide 250 mg Tablet and Zonisamide, you can take these medicines together if prescribed by your doctor. If you experience symptoms such as fever, sudden back pain, abdominal pain, blood in the urine, tiredness, loss of appetite, irregular heartbeat, decreased sweating, trouble thinking clearly, and rapid breathing, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AcetazolamideSodium salicylate
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Salicylic acid with Acetamide 250 mg Tablet can increase the risk of adverse effects.

How to manage the interaction:
Taking Acetamide 250 mg Tablet with Sodium salicylate together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms, like ringing in your ears, headache, feeling sick, throwing up, feeling dizzy, confused, seeing things that aren't there, breathing fast, having a fever, or having a seizure, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
AcetazolamideArsenic trioxide
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Taking Acetamide 250 mg Tablet with Arsenic trioxide may increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Acetamide 250 mg Tablet with Arsenic trioxide can possibly result in an interaction, but it can be taken if doctor has advised it. If you have any of these symptoms, it's important to contact a doctor right away: feeling dizzy or lightheaded, fainting, having a fast or pounding heartbeat, feeling weak or drowsy, being confused, experiencing muscle pain, or feeling nauseous or vomiting. Do not discontinue any medications without consulting a doctor.
AcetazolamideSalsalate
Severe
How does the drug interact with Acetamide 250 mg Tablet:
Co-administration of Acetamide 250 mg Tablet together with Salsalate can cause ringing in your ears, headache, nausea, vomiting, dizziness, confusion, hallucinations, rapid breathing, fever, seizure (convulsions).

How to manage the interaction:
There may be a possibility of interaction between Acetamide 250 mg Tablet and Salsalate, but it can be taken if prescribed by a doctor. If you have any of these symptoms, like ringing in your ears, headache, feeling sick, throwing up, feeling dizzy, feeling confused, breathing fast, having a fever, or having a seizure, make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

GLAUCOMA:

  • Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.
  • Limit coffee intake as it may increase pressure in the eye. Replace coffee with green tea.
  • Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

EPILEPSY:

  • Exercising regularly helps in maintaining weight and improving overall health. 
  • Rest well, and get plenty of sleep.
  • Avoid smoking and alcohol consumption.
  • Meditation and yoga can help lower stress, decrease pain sensitivity and improves coping skills.
  • Have a seizure response plan to help those around you know what to do.
  • Prepare your living area; small changes may help reduce the risk of physical injury during a seizure.
  • Understand what triggers seizures and try reducing or avoiding them.
  • Please pay attention to overall health, as it can help reduce seizure activity.
  • Install an alarm or emergency device to get assistance during a seizure attack.

FLUID RETENTION:

  • Limit salt intake.
  • Consume foods rich in magnesium, such as nuts, dark chocolate, whole grains, and leafy vegetables.
  • Include foods rich in vitamin B6, such as potatoes, bananas, meat, and walnuts.
  • Potassium reduces water retention, therefore, include potassium-rich foods such as avocados, tomatoes, and bananas.
  • Avoid refined carbohydrates.
  • Walking can help reduce fluid retention.

Habit Forming

No

Therapeutic Class

ANTIGLAUCOMA AGENTS

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Author Details

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Drug-Diseases Interactions

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ACETAZOLAMIDE-250MGOther aplastic anaemias
Severe
ACETAZOLAMIDE-250MGOther disorders of adrenal gland
Severe

Drug-Diseases Interactions

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ACETAZOLAMIDE-250MGOther aplastic anaemias
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of carbonic anhydrase inhibitors may rarely cause bone marrow suppression and blood dyscrasias at recommended dosages.

How to manage the interaction:
Acetamide 250 mg Tablet should be used with caution in patients with aplastic anemia ( body stops producing enough new blood cells), thrombocytopenia (low number of platelets in the blood) or thrombocytopenia purpura (low levels of platelets that prevent bleeding), leukopenia (low white blood cells in blood), agranulocytosis (extremely low levels of white blood cells), and hemolytic anemia (red blood cells are destroyed faster than they can be replaced). A baseline CBC and platelet count is recommended, as well as monitoring at regular intervals during therapy.
ACETAZOLAMIDE-250MGOther disorders of adrenal gland
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of carbonic anhydrase inhibitors is contraindicated in patients with adrenal insufficiency.

How to manage the interaction:
It should be used with extreme caution in patients with adrenal insufficency (adrenal glands don't make enough hormone, cortisol) and monitoring of electrolyte levels is recommended.
ACETAZOLAMIDE-250MGGlaucoma
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of carbonic anhydrase inhibitors is contraindicated in patients with closed-angle glaucoma.

How to manage the interaction:
It should be used with extreme caution in glaucoma patients.
ACETAZOLAMIDE-250MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of carbonic anhydrase inhibitors is contraindicated in patients with hypokalemia .

How to manage the interaction:
If you have symptoms such as constipation, extreme tiredness, muscle damage, tingling or numbness, contact your doctor immediately.
ACETAZOLAMIDE-250MGOther disorders of fluid, electrolyte and acid-base balance
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of carbonic anhydrase inhibitors is contraindicated in patients with hyponatremia .

How to manage the interaction:
If you have symptoms such as headache, confusion, nausea, vomiting, muscle weakness or cramps, extreme tiredness or restlessness, contact your doctor immediately.
ACETAZOLAMIDE-250MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of some carbonic anhydrase inhibitors is contraindicated in patients with severe kidney disease.

How to manage the interaction:
If you have symptoms such as pain, difficulty or discomfort while urinating, bad-smelling urine, cloudy or foamy urine, low back pain on one side, loss of appetite , flank pain between ribs and hips and fever not caused by an infection and that does not go away, contact your doctor immediately.
ACETAZOLAMIDE-250MGAlcoholic liver disease
Severe
How does the disease interact with Acetamide 250 mg Tablet:
The use of carbonic anhydrase inhibitors is contraindicated in patients with marked liver disease or cirrhosis.

How to manage the interaction:
It should be used with extreme caution in patients with mild to moderate liver disease, as clearance of the drug may be decreased. A dose reduction might be needed, and monitoring of the liver function is recommended.
ACETAZOLAMIDE-250MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Acetamide 250 mg Tablet:
carbonic anhydrase inhibitors should be administered cautiously in patients with respiratory acidosis

How to manage the interaction:
It should be used with caution in patients with respiratory acidosis and in conditions such as emphysema (lung disease that causes shortness of breath), pulmonary obstruction, etc. Respiratory status should be monitored during therapy.
ACETAZOLAMIDE-250MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Acetamide 250 mg Tablet:
Carbonic anhydrase inhibitor anticonvulsants should be administered cautiously in patients with reduced renal dysfunction.

How to manage the interaction:
It should be used with caution in patients with reduced kidney function and a dose adjustment may be required based on the level of impairment.
ACETAZOLAMIDE-250MGType 1 diabetes mellitus
Moderate
How does the disease interact with Acetamide 250 mg Tablet:
carbonic anhydrase inhibitors should be administered cautiously in patients with diabetes mellitus.

How to manage the interaction:
It should be used with caution in diabetic patients, and regular monitoring of blood glucose levels is recommended during therapy.
ACETAZOLAMIDE-250MGGout
Moderate
How does the disease interact with Acetamide 250 mg Tablet:
carbonic anhydrase inhibitors should be administered cautiously in patients with gout.

How to manage the interaction:
It should be used with caution in patients with gout and monitoring of uric acid levels is recommended.
ACETAZOLAMIDE-250MGDisorders resulting from impaired renal tubular function
Moderate
How does the disease interact with Acetamide 250 mg Tablet:
carbonic anhydrase inhibitors should be administered cautiously in patients with metabolic or hyperchloremic acidosis

How to manage the interaction:
Acetamide 250 mg Tablet should be used with caution in patients with metabolic or hyperchloremic acidosis or with conditions that lead to acidosis (renal disease, severe respiratory disorders, diarrhea).

Drug-Drug Interactions Checker List

  • DIGOXIN
  • WARFARIN
  • METFORMIN
  • GLICLAZIDE
  • PHENYTOIN
  • PRIMIDONE
  • CARBAMAZEPINE
  • TOPIRAMATE
  • PREDNISOLONE
  • DORZOLAMIDE
  • BRINZOLAMIDE
  • QUINIDINE
  • LITHIUM
  • CICLOSPORIN
  • SODIUM BICARBONATE

Special Advise

  • If you are due to have any surgery, inform the doctor/surgeon that you are taking Acetamide 250 mg Tablet 10's.
  • Your doctor may advise frequent blood tests whilst taking Acetamide 250 mg Tablet 10's.
  • Regular monitoring of serum electrolyte levels is advised.
  • Talk to your doctor immediately if you have thoughts of harming or killing yourself.

Disease/Condition Glossary

Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness. Usually, there are no symptoms for glaucoma initially, except the slow loss of vision gradually. However, some symptoms include visible rainbow-coloured circles around bright lights or blurred vision. Rarely, glaucoma can develop suddenly with intense pain in the eye, visual disturbance or nausea.

Epilepsy/Seizures: Seizures, also known as fits or convulsions, are a single occurrence of abnormal electrical activity in the brain, whereas epilepsy is a chronic neurological disorder characterized by recurrent seizures. Symptoms include mood changes, anxiousness, nausea, dizziness, weakness, headache, muscle jerking, spasms, loss of balance, teeth clenching, rapid blinking or eye movements, biting the tongue, confusion, and loss of consciousness. 

Fluid retention/oedema: It is a condition in which fluids are accumulated in the body tissues. Symptoms include bloating, weight fluctuations, puffiness of the face, abdomen, and hips, and swollen legs, ankles, and feet.

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