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Written By Veda Maddala , M Pharmacy
Reviewed By Sureshvarma D , MPharma
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About Acrofast PR 100mg/325mg/20mg Tablet

Acrofast PR 100mg/325mg/20mg Tablet belongs to a class of drugs called analgesics (pain relievers) used to reduce pain and swelling in conditions such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (pain and stiffness in the backbone). Arthritis is a condition that causes swelling of one or more joints resulting in pain and stiffness of joints that worsen over time. The symptoms of arthritis include joint pain, stiffness, redness, tenderness, swelling in and around joints, and reduced movement of joints.

Acrofast PR 100mg/325mg/20mg Tablet is a combination of three drugs, namely: Aceclofenac (nonsteroidal anti-inflammatory drug), Paracetamol (analgesic and antipyretic), and Rabeprazole (proton pump inhibitor).  Aceclofenac and Paracetamol work by inhibiting the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis. Rabeprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe.

Take Acrofast PR 100mg/325mg/20mg Tablet as prescribed by your doctor. You are advised to take Acrofast PR 100mg/325mg/20mg Tablet for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience indigestion, stomach pain, constipation, dizziness, nausea, and diarrhea. Most of these side effects of Acrofast PR 100mg/325mg/20mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Acrofast PR 100mg/325mg/20mg Tablet or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Acrofast PR 100mg/325mg/20mg Tablet as it may cause adverse effects in the baby if taken during the last 3 months of pregnancy. Acrofast PR 100mg/325mg/20mg Tablet may be excreted in breast milk. Therefore, avoid breastfeeding and consult a doctor. Acrofast PR 100mg/325mg/20mg Tablet is not recommended for children below 18 years of age as the safety and effectiveness were not established. Avoid consumption of alcohol with Acrofast PR 100mg/325mg/20mg Tablet as it may increase the risk of stomach bleeding. Drive only if you are alert as Acrofast PR 100mg/325mg/20mg Tablet may cause dizziness, tiredness, drowsiness, or vision problems.

Uses of Acrofast PR 100mg/325mg/20mg Tablet

Osteoarthritis, Rheumatoid arthritis and Ankylosing spondylitis

Directions for Use

Take Acrofast PR 100mg/325mg/20mg Tablet with food to avoid stomach upset or as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Acrofast PR 100mg/325mg/20mg Tablet contains Aceclofenac, Paracetamol and Rabeprazole.  Aceclofenac and Paracetamol inhibit the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, it helps in relieving pain and swelling associated with different types of arthritis such as osteoarthritis, rheumatoid arthritis and ankylosing spondylitis (pain and stiffness in the backbone). Rabeprazole blocks the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Acrofast PR 100mg/325mg/20mg Tablet or any other medicines, please tell your doctor. If you are pregnant or planning for pregnancy, please inform your doctor before taking Acrofast PR 100mg/325mg/20mg Tablet as it may cause adverse effects in the baby if taken during the last 3 months of pregnancy. Acrofast PR 100mg/325mg/20mg Tablet may be excreted in breast milk. Therefore, avoid breastfeeding and consult a doctor. Acrofast PR 100mg/325mg/20mg Tablet is not recommended for children below 18 years of age as the safety and effectiveness were not established. Avoid consumption of alcohol with Acrofast PR 100mg/325mg/20mg Tablet as it may increase the risk of stomach bleeding. Drive only if you are alert as Acrofast PR 100mg/325mg/20mg Tablet may cause dizziness, tiredness, drowsiness or vision problems.

Diet & Lifestyle Advise

  • Physical activity helps in strengthening muscles and relieves joint stiffness. Gentle activities like 20-30minutes of walking or swimming would be helpful.
  • Performing yoga may also help in improving joint flexibility and pain management.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Get adequate sleep as resting the muscles can help in reducing inflammation and swelling.
  • Follow heat or cold therapy, apply a cold or hot compress on the joints for 15-20minutes regularly.
  • Acupuncture, massage and physical therapy may also be helpful.
  • Eat foods rich in antioxidants such as berries, spinach, kidney beans, dark chocolate, etc.
  • Foods containing flavonoids such as soy, berries, broccoli, grapes and green tea help in reducing inflammation.
  • Avoid smoking and alcohol consumption.

Habit Forming

No

Therapeutic Class

ANALGESICS

Author Details

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FAQs

Acrofast PR 100mg/325mg/20mg Tablet contains Aceclofenac, Paracetamol and Rabeprazole. Aceclofenac and Paracetamol work by inhibiting the production of certain chemical substances such as prostaglandins that cause pain and swelling. Thereby, helps in relieving pain and swelling associated with different types of arthritis. Rabeprazole works by blocking the action of proton pumps that are involved in producing stomach acid. Thereby, it reduces the amount of acid produced by the stomach and prevents excess acid from flowing back into the food pipe.

Acrofast PR 100mg/325mg/20mg Tablet may increase the risk of heart problems such as heart attack, especially when used in high doses or for prolonged duration and in patients who are smokers, have high blood pressure, diabetes or high cholesterol. It is advised to inform your doctor if you have any of these conditions or have a history of heart problems or stroke before taking Acrofast PR 100mg/325mg/20mg Tablet. However, it is recommended to take Acrofast PR 100mg/325mg/20mg Tablet in the dose and for a duration as prescribed by your doctor.

You are not recommended to take Acrofast PR 100mg/325mg/20mg Tablet with warfarin as it may increase the risk of bleeding more easily. However, if you notice blood in urine or stools, dizziness, unusual bleeding or bruising, vomiting, weakness or headache, please consult a doctor immediately. If you are supposed to use these medicines together, you are advised to contact your doctor so that the dose may be adjusted appropriately to use safely.

Acrofast PR 100mg/325mg/20mg Tablet may impair fertility in females and make it more difficult to conceive. Therefore, if you are pregnant, planning for pregnancy or have difficulties conceiving, please consult your doctor before taking Acrofast PR 100mg/325mg/20mg Tablet.

Acrofast PR 100mg/325mg/20mg Tablet is not recommended for asthma patients as it may worsen the condition. Therefore, please inform your doctor if you have asthma or a history of asthma due to the use of aspirin or any other non-steroidal drugs.

Acrofast PR 100mg/325mg/20mg Tablet does not cure arthritis. Acrofast PR 100mg/325mg/20mg Tablet is only used to relieve symptoms of arthritis such as joint pain, swelling and stiffness.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • NAPROXEN
  • CELECOXIB
  • ETORICOXIB
  • ASPIRIN
  • KETOCONAZOLE
  • ITRACONAZOLE
  • PROPRANOLOL
  • ENALAPRIL
  • LISINOPRIL
  • LOSARTAN
  • CANDESARTAN
  • METHYLDOPA
  • CLONIDINE
  • FUROSEMIDE
  • AMILORIDE
  • HEPARIN
  • WARFARIN
  • CLOPIDOGREL
  • GLIBENCLAMIDE
  • GLICLAZIDE
  • TOLBUTAMIDE
  • MOXIFLOXACIN
  • CIPROFLOXACIN
  • OFLOXACIN
  • LEVOFLOXACIN
  • CHLORAMPHENICOL
  • ZIDOVUDINE
  • FLUVOXAMINE
  • PAROXETINE
  • CITALOPRAM
  • ESCITALOPRAM
  • SERTRALINE
  • FLUOXETINE
  • LITHIUM
  • METHOTREXATE
  • MIFEPRISTONE
  • DOMPERIDONE
  • METOCLOPRAMIDE
  • HYDROCORTISONE
  • PREDNISOLONE
  • CICLOSPORIN
  • TACROLIMUS

Special Advise

If you are elderly, a smoker, had a stroke previously, or have high blood pressure, diabetes or high cholesterol, please inform your doctor as these conditions may increase the risk of heart problems.

Disease/Condition Glossary

Osteoarthritis: It is a degenerative joint disease in which the two ends of the joints come together due to the breakdown of a protective covering of cartilage. Due to the absence of this protective covering, the joints rub against each other, leading to pain and stiffness. Symptoms of osteoarthritis include pain, stiffness, inflammation, and tenderness. The main reason for osteoarthritis is age, the older you are, the more likely you could get osteoarthritis, thus known as degenerative disease, meaning that the joints wear out as a person ages. Other reasons include past injuries such as torn cartilage, dislocated joints, and ligament injuries.

Rheumatoid arthritis: It is an auto-immune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms include pain, swelling, stiffness, deformities, and loss of joint function.

Ankylosing spondylitis: It causes pain and stiffness in the spine. The pain usually starts in the lower back and can spread to the neck, damaged joints, or other parts of the body. Symptoms of ankylosing spondylitis include decreased flexibility which usually leads to a hunched-forward posture, pain, and back and joints.

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