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Reviewed By Sunny S , MBBS
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Composition :

AZITHROMYCIN-500MG

Manufacturer/Marketer :

Human Care Remedies Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Activa-500 Tablet

Activa-500 Tablet belongs to a group of medicines known as macrolide antibiotics. It is used to treat various respiratory system bacterial infections (like pneumonia, bronchitis, tonsillitis, pharyngitis and sinusitis), skin infections (like acne and rosacea), ear infections, and sexually transmitted infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly.

Activa-500 Tablet slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival. Activa-500 Tablet does not treat a viral infection like flu or a common cold.

Activa-500 Tablet should only be taken if advised by your doctor. It can be taken with or without food but should be consumed at a fixed time for the best results. Activa-500 Tablet should not be consumed more than the recommended dose, to avoid unpleasant side effects. And also, the course should be completed even if you feel better as it is an antibiotic. Some common side effects of Activa-500 Tablet are diarrhoea, nausea, vomiting, and indigestion. An allergic reaction such as rashes, itching, swelling, and shortness of breath can occur in rare cases. Please consult your doctor if an allergic reaction becomes severe.

Tell your doctor if you have liver problems, muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). You should consult a doctor if you have had diarrhoea for more than four days. However, do not take any anti-diarrheal medicine until your doctor tells you. It is unknown whether Activa-500 Tablet harms the baby or passes into breast milk in pregnancy and breastfeeding state. Contacting a doctor before using Activa-500 Tablet during pregnancy and while breastfeeding is better. Avoid too much exposure to sunlight as Activa-500 Tablet can make your skin sensitive to sunburn. In this case, it is advisable to wear protective clothing or apply sunscreen (SPF 30 or higher) when you are outdoors.

Uses of Activa-500 Tablet

Bacterial infections

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Dispersible Tablet: Check the label for directions before use. Disperse the tablet in the prescribed amount of water and swallow the contents. Do not crush, chew or swallow as a whole.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Activa-500 Tablet in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

Activa-500 Tablet slows the growth or sometimes kills the harmful bacteria by preventing the production of proteins required by the bacteria for its survival. It prevents and treats bacterial infections like throat and sinus infections, chest infections (like bronchitis and pneumonia), ear infections, mouth and dental infections, eye infections, skin and tissue infections (like acne), and stomach and intestinal infections. It is better tolerated and has more effective tissue penetration than other similar antibiotics like erythromycin. Doctors prescribe Activa-500 Tablet for people who are intolerant to penicillin antibiotics. Besides this, it also helps prevent infection following burns, surgery or dental procedure, sexually transmitted infections, bone infections or scarlet fever (bacterial illness with strep throat).

Storage

Store in a cool and dry place away from sunlight
Side effects of Activa-500 Tablet
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
  • Consume more fruits, vegetables, and cruciferous foods like cabbage, kale, and broccoli.
  • Reduced alcohol intake can enhance liver enzyme function.
  • Oxidative stress can be managed by eating foods rich in antioxidants, such as vitamins C and E.
  • Liver function tests regularly can help manage increased levels of AST.
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.
  • Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
  • Consume vitamin C-rich foods as they aid iron absorption.
  • Limit tea, cocoa, and coffee as these can slow iron absorption.
  • Exercise regularly; however, do not overdo it.
  • Rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.

Drug Warnings

Tell your doctor if you have liver problems (jaundice), muscle problems (myasthenia gravis), heart rhythm disorder (arrhythmia), or electrolyte imbalance (low potassium or magnesium level). In rare cases, the use of Activa-500 Tablet can cause diarrhoea, so if you have watery or bloody diarrhoea, stop taking Activa-500 Tablet and call your doctor. However, do not take any anti-diarrheal medicine until your doctor tells you. It is unknown whether Activa-500 Tablet harms the baby during pregnancy. Consult your doctor if you are pregnant, planning for pregnancy or breastfeeding before using Activa-500 Tablet . Do not take Activa-500 Tablet if allergic to azithromycin or other macrolide antibiotics. Inform the doctor if you are using cholesterol-lowering drugs (statins like simvastatin, lovastatin etc.), anti-gout or anti-arthritis drugs (colchicine) and medicine for treating overactive bladder (tolterodine). Activa-500 Tablet is not recommended for the patients with pneumonia who are judged to be inappropriate for oral therapy due to moderate to severe illness or risk factors.

Drug-Drug Interactions

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ParacetamolTeriflunomide
Severe
ParacetamolLomitapide
Severe

Drug-Drug Interactions

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ParacetamolTeriflunomide
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Teriflunomide with Activa-500 Tablet may increase the risk or severity of Liver problems.

How to manage the interaction:
Taking Activa-500 Tablet with Teriflunomide together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
ParacetamolLomitapide
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Lomitapide and Activa-500 Tablet may increase the risk of severity of liver injury.

How to manage the interaction:
Although there is a possible interaction between Activa-500 Tablet and Lomitapide, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolOxazepam
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Activa-500 Tablet may decrease the excretion rate of Oxazepam which could result in a higher serum level.

How to manage the interaction:
Although there is a possible interaction between Oxazepam and Activa-500 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without a doctor's advice.
ParacetamolLeflunomide
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Activa-500 Tablet and Leflunomide may increase the risk of liver problems.

How to manage the interaction:
Although there is a possible interaction between Activa-500 Tablet and Leflunomide, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ParacetamolKetamine
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of ketamine and Activa-500 Tablet may decrease the effectiveness of Ketamine which could result in a higher blood level.

How to manage the interaction:
Although taking Ketamine and Activa-500 Tablet together can evidently cause an interaction, it can be taken if a doctor has suggested it. If you're feeling very sleepy or having trouble breathing, it's important to contact your doctor right away. Do not stop using any medications without a doctor's advice.
ParacetamolValdecoxib
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Activa-500 Tablet and Valdecoxib may increase the risk or severity of adverse effects.

How to manage the interaction:
Although there is a possible interaction between Activa-500 Tablet and Valdecoxib, you can take these medicines together if prescribed by a doctor. However, if the side effects worsen, please consult a doctor.
ParacetamolKetoconazole
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Activa-500 Tablet and Ketoconazole may increase the risk of liver injury.

How to manage the interaction:
Although there is a possible interaction between Activa-500 Tablet and Ketoconazole, you can take these medicines together if prescribed by a doctor. However, if you have joint pain or swelling, fever, chills, unusual bleeding or bruising, skin rash, itching, over-tiredness, nausea, vomiting, loss of appetite, stomach pain, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, contact a doctor immediately as these may be signs and symptoms of liver damage. Do not discontinue the medication without consulting a doctor.
ParacetamolMipomersen
Severe
How does the drug interact with Activa-500 Tablet:
Co-administration of Mipomersen with Activa-500 Tablet may increase the risk or severity of liver injury.

How to manage the interaction:
There may be a possibility of interaction between Activa-500 Tablet and Mipomersen, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to take probiotics after taking the full course of Activa-500 Tablet to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • Include more fibre-enriched food in your diet, as it can be easily digested by gut bacteria which helps stimulate their growth. Thus fibre foods may help restore healthy gut bacteria after taking a course of antibiotics. Whole grains like whole-grain bread, and brown rice, should be included in your diet.
  • Avoid taking too much calcium enriched foods and drinks as it might affect the working of Activa-500 Tablet .
  • Avoid intake of alcoholic beverages with Activa-500 Tablet as it can make you dehydrated and affect your sleep. This can make it harder for your body to aid the Activa-500 Tablet in fighting off infections.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Activa-500 Tablet Substitute

Substitutes safety advice
  • Aquris Azithcin 500 Tablet 3's

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    24.00per tablet
  • Azithral-500 Tablet 5's

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    23.68per tablet
  • Azee-500 Tablet 5's

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    23.68per tablet
  • Azax-500 Tablet 3's

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    23.70per tablet
  • Azicip 500 Tablet 3's

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    23.70per tablet

Drug-Diseases Interactions

verifiedApollotooltip
AZITHROMYCIN-500MGMental and behavioural disorders due to use of alcohol
Severe
AZITHROMYCIN-500MGHepatic failure, not elsewhere classified
Severe

Drug-Diseases Interactions

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AZITHROMYCIN-500MGMental and behavioural disorders due to use of alcohol
Severe
How does the disease interact with Activa-500 Tablet:
Chronic alcoholics may have a higher risk of hepatotoxicity when using Activa-500 Tablet. Patients using Activa-500 Tablet may cause severe liver damage, including acute liver failure that required a liver transplant and resulted in death.

How to manage the interaction:
Activa-500 Tablet should be used with caution in patients who consume three or more alcoholic drinks a day. Avoid alcohol consumption while taking Activa-500 Tablet. If you have nausea, vomiting, fever, rash, anorexia (eating disorder), over-tiredness, upper right stomach pain, dark urine, and jaundice, contact your doctor as these may be signs and symptoms of liver injury.
AZITHROMYCIN-500MGHepatic failure, not elsewhere classified
Severe
How does the disease interact with Activa-500 Tablet:
The liver predominantly converts Activa-500 Tablet to inactive forms. Patients with hepatic impairment may be more prone to toxicity because their minor metabolic pathways are more active.

How to manage the interaction:
Activa-500 Tablet should be used with caution in patients with kidney insufficiency. Also, it is recommended to avoid drinking alcohol while taking Activa-500 Tablet.

FAQs

Do not take antacids that contain aluminium or magnesium hydroxide within 2 hours before or after you take Activa-500 Tablet . These antacids can interact with Activa-500 Tablet and make them less effective when taken at the same time.

Never stop the treatment with Activa-500 Tablet on your own as the infection may come back again (relapse) if the prescribed treatment is not completely taken. Before stopping Activa-500 Tablet once discuss this with your doctor.

If you forget to take Activa-500 Tablet , take your dose as soon as possible. If it is almost time for the next dose, just skip that dose and take the next one when it is due. If in doubt, please contact your doctor. Do not take a double dose to make up for a forgotten dose

Activa-500 Tablet contains lactose monohydrate so if you have intolerance towards sugars, consult your doctor before starting Activa-500 Tablet .

Activa-500 Tablet can cause diarrhoea, which may be a sign of a new infection. If you have diarrhoea that is watery or bloody, call your doctor. Do not use anti-diarrhoea medicine unless your doctor tells you to.

You should avoid taking Activa-500 Tablet if you have colitis (intestine inflammation), heart rhythm disorder, liver disease (like jaundice), and muscle problem (like myasthenia gravis). Contact your doctor if you have these conditions before taking Activa-500 Tablet .

No, it is a Schedule H drug that can be taken only if your doctor has prescribed it. Taking it on your own or self-medication can cause unwanted side-effects and lead to antibiotic resistance thereby lowering its efficiency.

Yes in some cases, people using Activa-500 Tablet may get a fungal skin infection known as thrush. It happens because Activa-500 Tablet also kills harmless bacteria that protects against thrush.

Clinical evidence suggests that Activa-500 Tablet does not affect the working of any oral birth control pills and contraceptives devices.

Drug-Drug Interactions Checker List

  • DOMPERIDONE
  • PIMOZIDE
  • AMISULPRIDE
  • ERGOTAMINE
  • DIHYDROERGOTAMINE
  • SIMVASTATIN
  • TOLTERODINE
  • COLCHICINE

Disease/Condition Glossary

Bacterial infection: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. When you get infected with bacteria, you can experience generalized symptoms like fevers, chills, and fatigue. Bacteria are of various forms comprising commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. Few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine can make you more prone to bacterial infection.

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