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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Composition :

CISPLATIN-50MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Adcist-50 Injection

Adcist-50 Injection belongs to the group of medicines called cytostatics used alone or in combination with other cytostatic medicines to treat tumours of the ovary, testis, bladder, neck and head epithelial tumours, lung cancer, and cervical cancer in combination with radiotherapy. Cancer is a disease in which abnormal cells divide uncontrollably and damage body tissues.
 
Adcist-50 Injection contains Cisplatin, which works by preventing the growth of cancer cells and eventually destroying them. Thereby, it helps treat cancer.
 
In some cases, Adcist-50 Injection may cause side effects such as nausea, vomiting, tiredness, hair loss, pain or redness at the site of injection. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Adcist-50 Injection if you are pregnant or breastfeeding. Both women and men should seek advice on fertility preservation before treatment and use effective contraception during treatment. Adcist-50 Injection is not recommended for children as safety and effectiveness have not been established. Inform the doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Adcist-50 Injection

Tumours of the ovary, testis, bladder, neck and head epithelial tumour, lung cancer, and cervical cancer.

Directions for Use

Adcist-50 Injection will be administered under the supervision of a qualified doctor experienced in the use of cancer chemotherapeutic agents.

Medicinal Benefits

Adcist-50 Injection contains Cisplatin, which belongs to the group of medicines called platinum-containing compounds used to treat testicular and ovarian cancer that has not improved or has worsened after treatment with radiation therapy or other medicines. It is also used alone or in combination with other medicines for bladder cancer, which has not been treated with radiotherapy or surgery alone. This medicine is also indicated in the treatment of head and neck cancer, lung cancer, and cervical cancer in combination with radiotherapy. Adcist-50 Injection prevents the growth of cancer cells and eventually destroys them. Thereby, it helps treat cancer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Adcist-50 Injection if you are allergic to any of its components, if you are pregnant or breastfeeding, if you have severe kidney disease, hearing difficulties, myelosuppression (bone marrow does not make enough platelets or blood cells), are dehydrated, or if you have taken or plan to receive yellow fever vaccination. Inform the doctor if you have low blood count, peripheral neuropathy or have had radiation therapy to your head. Consult the doctor immediately if you become pregnant during treatment with Adcist-50 Injection. Seek immediate medical attention if you experience symptoms of an allergic reaction (itchy rash, swelling of the hands, feet, face, ankles, throat, lips or mouth, flushing, and feeling faint), heart attack (severe chest pain radiating to the arm or jaw with sweating, nausea, and breathlessness), stroke, brain dysfunction (slurred speech, sometimes blindness, confusion, memory loss and paralysis), kidney problems (unusual tiredness or weakness, decreased urination, or swelling of the face, arms, hands, feet, ankles, or lower legs), or hearing problems (ringing in the ears, dizziness, or hearing loss).

Drug-Drug Interactions

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CisplatinAmiodarone
Severe
CisplatinCidofovir
Severe

Drug-Drug Interactions

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CisplatinAmiodarone
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Coadministration of Adcist-50 Injection 50 ml with amiodarone may increase the risk of abnormal cardiac rhythms and raises Amiodarone blood levels.

How to manage the interaction:
Although taking Adcist-50 Injection 50 ml with amiodarone may cause an interaction, it is safe to do so if your doctor has prescribed it. If you have a cardiac problem or electrolyte imbalances, you may be more vulnerable. If you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, consult a doctor . Do not stop taking any medications without visiting a doctor.
CisplatinCidofovir
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Taking cidofovir and Adcist-50 Injection 50 ml can increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between Adcist-50 Injection 50 ml and cidofovir, you can take these medicines together if prescribed by your doctor. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm contact your doctor immediately. Before beginning cidofovir medication, you might need to wait at least seven days if you have been receiving Adcist-50 Injection 50 ml. Do not discontinue any medications without consulting a doctor
CisplatinClozapine
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Combining Adcist-50 Injection 50 ml with Clozapine can increase the risk of neutropenia (Infection).

How to manage the interaction:
Although there is a possible interaction between Adcist-50 Injection 50 ml and Clozapine, you can take these medicines together if prescribed by your doctor. If you experience symptoms such as infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, or pain during urination, contact your doctor immediately." Do not discontinue any medications without first consulting your doctor.
CisplatinLeflunomide
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Using leflunomide together with Adcist-50 Injection 50 ml may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Leflunomide with Adcist-50 Injection 50 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice symptoms like fever, chills, sore throat, or muscle aches, contact your doctor immediately. Other symptoms to look out for include diarrhoea, shortness of breath, weight loss, and pain or burning while urinating." Do not discontinue any medications without consulting your doctor.
CisplatinTenofovir alafenamide
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
The combined use of Adcist-50 Injection 50 ml and Tenofovir alafenamide can increase the risk of kidney problems.

How to manage the interaction:
Taking Adcist-50 Injection 50 ml and Tenofovir alafenamide together can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
CisplatinInfliximab
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Combining Infliximab with Adcist-50 Injection 50 ml can increase the risk or severity of developing serious infections.

How to manage the interaction:
Co-administration of Infliximab with Adcist-50 Injection 50 ml can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, a sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.
CisplatinDeferasirox
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Deferasirox may cause kidney problems and combining it with Adcist-50 Injection 50 ml may increase that risk.

How to manage the interaction:
Although taking Adcist-50 Injection 50 ml and Deferasirox together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, fluid retention, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, or irregular heart rhythm, seek immediate medical attention. Drink plenty of water if you experience diarrhoea or vomiting while taking these medications, as dehydration can potentially affect the kidneys. Do not discontinue any medications without a doctor's advice.
CisplatinThalidomide
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Taking thalidomide together with Adcist-50 Injection 50 ml may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Adcist-50 Injection 50 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
CisplatinEtanercept
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
When Etanercept is used with Adcist-50 Injection 50 ml, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Etanercept and Adcist-50 Injection 50 ml, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
CisplatinTacrolimus
Severe
How does the drug interact with Adcist-50 Injection 50 ml:
Taking tacrolimus with Adcist-50 Injection 50 ml can increase the risk of kidney problems.

How to manage the interaction:
Although taking tacrolimus and Adcist-50 Injection 50 ml together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Adcist-50 Injection Substitute

Substitutes safety advice
  • UNIPLATIN 50MG INJECTION

    by Others

    317.70per tablet
  • Cismax 50 mg Injection 50 ml

    by Others

    7.11per tablet
  • Cistero-50 Injection 50 ml

    by Others

    7.13per tablet
  • Cislee-50 Injection 50 ml

    by Others

    6.35per tablet
  • Cisnak 50 Injection

    by Others

    306.00per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Adcist-50 Injection works by slowing or stopping the growth of cancer cells.

Adcist-50 Injection may potentially cause permanent sterility in men. Both women and men are recommended to seek advice on fertility preservation (the process of saving/protecting sperm, eggs or reproductive tissue) prior to treatment.

Consult the doctor before having any immunisations whilst on treatment with Adcist-50 Injection.

Adcist-50 Injection may cause serious kidney problems, more often in older people. Consult the doctor immediately if you experience unusual tiredness or weakness, decreased urination, or swelling of the face, arms, hands, feet, ankles, or lower legs.

Adcist-50 Injection is not recommended for patients with hearing problems. Adcist-50 Injection may cause serious hearing problems. In some cases, hearing loss might be permanent. Call your doctor immediately if you experience ringing in the ears, dizziness, or hearing loss.

Drug-Drug Interactions Checker List

  • PHENYTOIN
  • AMPHOTERICIN B
  • IFOSFAMIDE
  • BLEOMYCIN
  • METHOTREXATE
  • PACLITAXEL

Special Advise

  • Regular liver/kidney function tests and blood tests are advised as Adcist-50 Injection may cause problems with blood, kidneys, and liver.
  • Women must use reliable contraception during treatment and for seven months after receiving the last dose.
  • Men with female partners of childbearing potential are advised to use effective contraception during treatment and for four months after the last dose.

Disease/Condition Glossary

Testicular cancer: It is the cancer in the male organs that make testicles/sperm and male hormones. A feeling of heaviness in the scrotum and a lump in either testicle are the symptoms of testicular cancer.

Ovarian cancer: Ovarian cancer is a cancer that begins in the female reproductive organs where the ovaries/eggs are formed. It often has no symptoms in the early stages. Later stages are associated with symptoms such as weight loss and loss of appetite. 

Bladder cancer: It is a cancer that begins in the bladder. It typically affects older adults. The most common symptom is blood in the urine.

Head and neck cancer: It is a group of cancers of the mouth, nose, sinuses, or throat. A significant risk factor is smoking. Symptoms include a sore/lump that does not heal, trouble swallowing, persistent sore throat, and voice change.

Lung cancer: It is a disease that begins in the lungs and mostly occurs in people who smoke. Symptoms of lung cancer are cough, wheezing, chest pain, and weight loss.

Cervical cancer: It is the malignant tumour of the cervix (lowermost part of the uterus). Symptoms include bleeding between periods and after sexual intercourse, foul-smelling white discharge, low back pain, or lower abdominal pain.

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