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rxMedicinePrescription drug

Composition :

BUPRENORPHINE-0.2MG

Manufacturer/Marketer :

Rusan Pharma Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Addnok 0.2 mg Tablet

Addnok 0.2 mg Tablet belongs to a class of drugs called 'opioid agonists' primarily used to treat opioid addiction (narcotics) like morphine, heroin, etc. It is also used to treat, prevent and treat moderate to severe pain. Drug addiction, also called substance use disorder, is a disease that affects a person's brain and behaviour and leads to an inability to control the use of a legal or illegal drug or medication.

Addnok 0.2 mg Tablet contains 'Buprenorphine', an opioid partial agonist-antagonists that prevent withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It has been approved for the treatment of narcotic-use disorders. A combination of buprenorphine and naloxone is prescribed for use in the treatment of opioid dependence. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain.

Addnok 0.2 mg Tablet should be used as prescribed by your doctor. The dose will be decided based on your medical condition. This medicine may cause certain side effects, in drowsiness, dry mouth, vomiting, blurred vision, constipation, dizziness or tiredness. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Addnok 0.2 mg Tablet should be avoided if you are allergic to it. Do not take Addnok 0.2 mg Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Addnok 0.2 mg Tablet is not recommended for children below 18 years of age. Addnok 0.2 mg Tablet is a habit-forming drug, and hence there is a risk of dependence on Addnok 0.2 mg Tablet . Therefore, before stopping Addnok 0.2 mg Tablet , contact a doctor as it may cause withdrawal symptoms like anxiety, increased heart rate, tremors or general unwell feeling. Addnok 0.2 mg Tablet may decrease fertility in men and women. Inform your doctor if you have respiratory disorders, heart diseases, high blood pressure, and liver or kidney disease before starting treatment with Addnok 0.2 mg Tablet . Avoid consuming alcohol along with Addnok 0.2 mg Tablet as it could lead to increased dizziness.

Uses of Addnok 0.2 mg Tablet

Opioid (drug) addiction, Pain

Directions for Use

Sublingual tablet: Place the tablet under your tongue and allow it to dissolve with your mouth closed. Do not chew the tablet or swallow it whole.

Medicinal Benefits

The Addnok 0.2 mg Tablet contains Buprenorphine as a substitution (replacement) treatment in patients addicted to opioid drugs (heroin and morphine, etc.). It prevents or reduces the unpleasant withdrawal symptoms experienced when addicts stop using opioid drugs. It also provides pain relief by acting on specific receptors in the brain and helps in relieving pain. Compared to other opioid analgesics like methadone, Addnok 0.2 mg Tablet has the advantage of having less sedation (sleepiness), decreased respiratory depression, decreased risk of diversion, fewer withdrawal symptoms and lower risk of toxicity at higher doses. 

Storage

Keep Addnok 0.2 mg Tablet out of the sight and reach of children.
Side effects of Addnok 0.2 mg Tablet
  • Drink water or other clear fluids.
  • To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
  • Include bland foods like rice, toast, crackers, and rice in your diet.
  • Avoid lying down immediately after eating as it may cause indigestion or heartburn.
  • Avoid acidic and spicy food as it may cause indigestion.

Drug Warnings

Please do not stop taking Addnok 0.2 mg Tablet suddenly, as it may cause withdrawal symptoms. Avoid frequent or high doses as it may lead to addiction. If you are known to be allergic to Addnok 0.2 mg Tablet or any other medicines, please tell your doctor.  Do not take Addnok 0.2 mg Tablet if you are pregnant or breastfeeding, as it may cause adverse effects on the baby. Addnok 0.2 mg Tablet is not recommended for children below 18 years of age.  Avoid consuming alcohol with Addnok 0.2 mg Tablet as it may increase the risk of side effects. Do not use this medicine if you have used an MAO inhibitor (antidepressants) in the past 14 days, as a dangerous drug interaction could occur. Addnok 0.2 mg Tablet should be taken with extreme caution in patients who have a history of alcoholism or drug abuse. Inform your doctor if you have severe breathing problems, asthma, delirium tremens (confusion and shaking after stopping drinking alcohol), hallucinations (seeing and hearing things that are not there), kidney or liver problems, head injury or brain disease, low blood pressure, urinary disorders (especially linked to enlarged prostate), thyroid problems, adrenocortical disorder (Addison’s disease), depression or other conditions that are treated with antidepressants. 

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical

Drug-Drug Interactions

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BuprenorphineAlvimopan
Critical
How does the drug interact with Addnok 0.2 mg Tablet:
Using alvimopan together with Addnok 0.2 mg Tablet can cause side effects (abdominal pain, nausea, vomiting, and diarrhea).

How to manage the interaction:
Taking Alvimopan with Addnok 0.2 mg Tablet is not recommended, consult a doctor before taking it. Do not stop using any medications without talking to a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Taking Ziprasidone with Addnok 0.2 mg Tablet can increase the risk of serious side effects.

How to manage the interaction:
Taking Ziprasidone with Addnok 0.2 mg Tablet is not recommended, but it can be taken together if prescribed by a doctor. However, consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Coadministration of Addnok 0.2 mg Tablet with primidone can increase the risk or severity of side effects such as breathing problems.

How to manage the interaction:
Although there is an interaction between Addnok 0.2 mg Tablet and primidone, it can be taken if your doctor has advised it. However, if you experience abdominal cramping, loss of appetite, nausea, vomiting, diarrhea, weight loss, excessive sweating, goose bumps, fever, chills, watery eyes, runny nose, sneezing, or yawning, consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BuprenorphinePethidine
Severe
How does the drug interact with Addnok 0.2 mg Tablet:
Using Addnok 0.2 mg Tablet together with Pethidine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Pethidine and Addnok 0.2 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Using Addnok 0.2 mg Tablet together with Clomipramine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking clomipramine and Addnok 0.2 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, contact a doctor immediately if you experience any symptoms such as confusion, hallucinations, seizures, changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
Using Pregabalin together with Addnok 0.2 mg Tablet causes central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Addnok 0.2 mg Tablet and Pregabalin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in- judgment, reaction speed and motor coordination, consult the doctor immediately. Avoid driving or operating dangerous machinery. Do not exceed the doses, frequency, or duration of usage advised by the doctor. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
When Addnok 0.2 mg Tablet is used with gatifloxacin, it may lead to significant adverse effects (respiratory difficulties or unconsciousness).

How to manage the interaction:
Concomitant administration of Addnok 0.2 mg Tablet alongside gatifloxacin can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor. You should avoid driving or operating hazardous machinery while taking these medications.
How does the drug interact with Addnok 0.2 mg Tablet:
Using Lurasidone together with Addnok 0.2 mg Tablet can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Despite the fact that Addnok 0.2 mg Tablet and Lurasidone interact, it can be taken if prescribed by a doctor. Consult a doctor if you develop dizziness, drowsiness, difficulty concentrating, or problems in judgment, reaction speed, or movement control. Do not discontinue any medications without consulting a doctor.
How does the drug interact with Addnok 0.2 mg Tablet:
When Addnok 0.2 mg Tablet is used with Vigabatrin, it may increase the risk of side effects such as respiratory difficulties.

How to manage the interaction:
Co-administration of Addnok 0.2 mg Tablet alongside Vigabatrin can result in an interaction, it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. You should avoid driving or operating hazardous machinery. Do not discontinue any medications without consulting a doctor.
Severe
How does the drug interact with Addnok 0.2 mg Tablet:
Using Addnok 0.2 mg Tablet together with Nabilone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Nabilone and Addnok 0.2 mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. It's important to keep an eye on your health and be aware of any changes. Doctor can recommend other options that won't cause any problems. If you notice any symptoms like feeling very tired or having trouble breathing, make sure to contact a doctor right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Do regular exercise such as swimming or walking.
  • Drink plenty of water while taking Addnok 0.2 mg Tablet to avoid dry mouth.
  • Maintain a fibre-rich diet and eat plenty of fresh fruits and vegetables to avoid constipation while taking Addnok 0.2 mg Tablet .
  • Avoid consumption of alcohol and quit smoking.

Side Effects of Addnok 0.2 mg Tablet

  • Weakness
  • Anxiety
  • Nervousness
  • Dizziness
  • Drowsiness
  • Headache
  • Orthostatic hypotension (a sudden dip of blood pressure on standing)
  • Constipation
  • Diarrhea
  • Nausea
  • Vomiting
  • Sweating

Habit Forming

Yes

Therapeutic Class

OPIOID ANTAGONISTS

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Addnok 0.2 mg Tablet consists of Buprenorphine is an opioid partial agonist. It prevents withdrawal symptoms in patients who stop taking opioid drugs by producing similar effects to these drugs. It also provides pain relief by acting on specific receptors in the brain that change how your body feels and responds to pain.

Yes, Addnok 0.2 mg Tablet may cause withdrawal symptoms such as sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful. Therefore, if you experience difficulty while taking Addnok 0.2 mg Tablet , do not stop taking it suddenly and consult your doctor so that the dose may be reduced gradually to avoid withdrawal symptoms.

Chronic use of opioids may cause reduced fertility (ability to have children) in females and males of reproductive potential. It is not known whether these effects on fertility are reversible. However, it is essential to talk to your doctor before starting treatment with Addnok 0.2 mg Tablet if you think you may want to have a baby in the future.

No, you are not recommended to take Addnok 0.2 mg Tablet with antidepressants (medicines used to treat depression), and antipsychotics (medicines used to treat bipolar disorder and psychosis) as co-administration of these medicines with Addnok 0.2 mg Tablet may cause life-threatening respiratory depression and death have occurred. However, please consult a doctor before taking Addnok 0.2 mg Tablet with other medicines.

Yes, Addnok 0.2 mg Tablet may cause addiction, especially if taken for a prolonged time. Therefore, Addnok 0.2 mg Tablet should be given only for a short duration under strict medical supervision, particularly to patients susceptible to drug abuse. Take Addnok 0.2 mg Tablet only as advised by a doctor, as overuse or misuse of Addnok 0.2 mg Tablet can lead to overdose or death.

Some prescription-based opioid pain medications include codeine, fentanyl, hydromorphone, meperidine morphine, oxymorphone, oxycodone, hydrocodone and propoxyphene.

Drug-Drug Interactions Checker List

  • DIAZEPAM
  • CODEINE
  • MORPHINE
  • METHADONE
  • FLUOXETINE
  • ESCITALOPRAM
  • CITALOPRAM

Special Advise

  • Do not take Addnok 0.2 mg Tablet for a prolonged time, as it may lead to mental or physical dependence on Addnok 0.2 mg Tablet .
  • To avoid getting addicted to this drug, take it in prescribed quantities and as directed by your doctor. Do not self-medicate.
  • Addnok 0.2 mg Tablet causes drowsiness. Avoid doing activities that require your complete focus and attention, like driving when on this drug.
  • An abrupt stoppage of Addnok 0.2 mg Tablet can lead to significant withdrawal symptoms. Always discuss with your doctor about decreasing the dosage before completely stopping its usage.
  • Avoid consuming alcohol while on this medication, as it can lead to dangerous side effects.

Disease/Condition Glossary

Drug addiction: It is also called substance use disorder. It is a psychological condition that affects a person's brain and behaviour and leads to an inability to control legal or illegal drug or medication use. Opioid analgesics, such as morphine or diamorphine (heroin), are often subject to abuse, leading to dependence (addiction). If you are addicted to these drugs, you need a regular dose to feel ‘normal’. Otherwise, you will develop withdrawal symptoms within a day or so of the last dose. Withdrawal symptoms include sweating, feeling hot and cold, runny eyes and nose, feeling or being sick, diarrhoea, stomach cramps, poor sleep, and just feeling awful.

Pain: Pain is an unpleasant emotion brought on by an illness or injury. Acute (short-term) or chronic pain both exist (long-term). It may be widespread (body-wide aches) or localised (pain in a specific body area). Since different people have varying pain tolerance levels, pain is highly subjective. Even though pain is uncomfortable and inconvenient, it can provide clues as to what is wrong with the body. Cramps, headaches, bone fractures, stomach pain, arthritis (swelling of one or more joints), muscle strain or overuse, cuts, the flu, fibromyalgia, and irritable bowel syndrome are a few conditions that can cause pain (muscle pain with stiffness and tenderness).

Have a query?

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Alcohol

Unsafe

Avoid consumption of alcohol while using Addnok 0.2 mg Tablet as it may lead to a worsening of side effects of this medicine.

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Pregnancy

Unsafe

Addnok 0.2 mg Tablet is not recommended for use during pregnancy as it may cause life-threatening withdrawal symptoms in the newborn. Hence, if you are pregnant or planning pregnancy, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may prescribe this medicine if the benefits outweigh the risks.

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Breast Feeding

Unsafe

It may be unsafe to use during breastfeeding as it passes into breastmilk and may cause sleepiness and decreased heart rate in your infant. It is not recommended for use in breastfeeding. Hence, if you are breastfeeding, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may suggest you stop feeding while on treatment with this medicine.

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Driving

Unsafe

Addnok 0.2 mg Tablet may cause dizziness, blurred vision or drowsiness in some people. It is an offence to drive if Addnok 0.2 mg Tablet affects you. Therefore, avoid driving if you feel drowsy, dizzy or experience any vision problems after taking Addnok 0.2 mg Tablet .

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Liver

Caution

If you have a pre-existing or a history of liver disease, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Kidney

Caution

If you have a pre-existing or a history of kidney disease, inform your doctor before taking Addnok 0.2 mg Tablet . Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.

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Children

Unsafe

Addnok 0.2 mg Tablet is not recommended for children below 18 years of age as safety and effectiveness have not been established.

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