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  1. Home
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  3. Adfill Injection 0.6 ml

Adfill Injection 0.6 ml, Pack of 1 INJECTION
Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
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Whats That

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Composition :

PEGFILGRASTIM-6MG

Manufacturer/Marketer :

Adley Formulations

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Adfill Injection

Adfill Injection belongs to the class of medicine called 'hematopoietic agent' used to treat neutropenia, a deficiency of specific white blood cells caused by cancer, bone marrow transplant, chemotherapy, or other diseases. Adfill Injection helps reduce the chance of infection in cancer patients and those receiving chemotherapy medicines. Neutropenia is a condition in which the quantity of neutrophils (white blood cells) in the blood is reduced.

Adfill Injection contains 'Pegfilgrastim,' a growth factor that stimulates the formation of white blood cells and helps reduce the chances of infection in cancer patients receiving chemotherapy.

Adfill Injection will be administered by a healthcare professional. Sometimes, you may experience injection site responses such as pain, redness, or swelling. You may also experience nausea, headaches, bone pain and pain in the extremity. Most of these side effects do not necessitate medical treatment and will gradually fade over time. However, if you suffer these side effects regularly, you should consult your doctor.

Do not use Adfill Injection without the doctor's advice if you have a skin reaction or irritation to any medicine. Consult your doctor before using the Adfill Injection if you are pregnant or breastfeeding. Let your doctor know if you suffer from renal dysfunction, blood cancer, or leucocytosis (high white blood cell count). Regular blood tests are recommended to check the number of white blood cells in the body. Keep your doctor informed about your medical condition and all the medicines you take to rule out any side effects.

Uses of Adfill Injection

Neutropenia

Directions for Use

Adfill Injection will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Adfill Injection contains 'Pegfilgrastim,' which is a growth factor. It belongs to the cytokine family of proteins and is extremely similar to a natural protein (granulocyte-colony stimulating factor) produced by the body. Adfill Injection acts by encouraging the bone marrow to generate more white blood cells, aiding infection resistance. Adfill Injection is used to boost white blood cell count following cancer treatment or chemotherapy, bone marrow transplantation, severe persistent neutropenia, neutropenia in HIV patients, and before stem cell donation.

Storage

Store in a cool and dry place away from sunlight
Side effects of Adfill Injection 0.6 ml
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
  • Regular exercise, like swimming, walking, and yoga, can help reduce bone pain by strengthening muscles and releasing natural pain relievers.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and massage, can help ease bone pain and improve movement.
  • Mind-body techniques, like relaxation, meditation, and hypnosis, can reduce pain and help control muscle tension that comes with bone pain.
  • Acupuncture may help reduce bone pain by triggering the release of natural painkillers and easing nerve discomfort.
  • Avoid sitting for long periods; take short walks or stretch regularly.
  • Herbs like turmeric and ginger might help with bone pain.
  • Eat a diet rich in calcium, vitamin D, and protein for strong bones and muscles.
  • Quit smoking and limit alcohol.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
  • Regular exercise, like swimming, walking, and yoga, can help reduce bone pain by strengthening muscles and releasing natural pain relievers.
  • Physical therapy, including stretching, strengthening exercises, TENS (a type of therapy using electrical pulses), and massage, can help ease bone pain and improve movement.
  • Mind-body techniques, like relaxation, meditation, and hypnosis, can reduce pain and help control muscle tension that comes with bone pain.
  • Acupuncture may help reduce bone pain by triggering the release of natural painkillers and easing nerve discomfort.
  • Avoid sitting for long periods; take short walks or stretch regularly.
  • Herbs like turmeric and ginger might help with bone pain.
  • Eat a diet rich in calcium, vitamin D, and protein for strong bones and muscles.
  • Quit smoking and limit alcohol.
  • Incorporate foods high in antioxidants, such as tomatoes, leafy greens, and berries, to prevent inflammation.
  • Encourage stress-relieving activities like yoga, deep breathing, and meditation.
  • Support the immune system and help the body rid itself of toxins.
  • Regularly check white blood cell counts to monitor the effectiveness of therapy and make any necessary modifications.
  • Regularly monitor uric acid levels to keep them in a healthy range.
  • Your doctor may prescribe medications to lower uric acid levels.
  • Limit your alcohol consumption as it can raise uric acid levels.
  • Weight management helps to reduce uric acid production.
  • Limit purine-rich foods like organ meats, seafood, red meat, poultry, and certain fish

Drug Warnings

Do not use Adfill Injection without the doctor's advice if you had a skin reaction or irritation to any medicine. Consult your doctor before using Adfill Injection if you are pregnant or breastfeeding. Let your doctor know if you are suffering from renal dysfunction, blood cancer, leucocytosis (high white blood cell count). Keep your doctor informed about your medical condition and all the medicines you are taking to rule out any side effects. Regular blood tests will be taken to monitor the number of white blood cells in the body. Adfill Injection is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficacy might get lost.

Drug-Drug Interactions

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No Drug - Drug interactions found in our data. We may lack specific data on this medicine and are actively working to update our database. Consult your doctor for personalized advice

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Consume a well-balanced and healthy food to aid in your recovery.
  • Avoid eating processed food or frozen food. 
  • Consume antioxidant-rich foods such as berries, spinach, kidney beans, dark chocolate, and so on.
  • Flavonoid-rich foods aid in the reduction of inflammation. Soy, berries, broccoli, grapes, and green tea are examples.
  • Limit or quit the consumption of alcohol.
  • Quit smoking.

Habit Forming

No

Therapeutic Class

HEMATOPOIETIC

Adfill Injection Substitute

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Author Details

Bayyarapu Mahesh KumarDoctor badge

Written By

Bayyarapu Mahesh Kumar

M Pharmacy

Santoshini Reddy GDoctor badge

Reviewed By

Santoshini Reddy G

M Pharmacy

Last Updated

Jul 8, 2025 | 9:44 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

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PEGFILGRASTIM-6MGUnspecified nephritic syndrome
Severe
PEGFILGRASTIM-6MGMyeloid leukaemia
Severe

Drug-Diseases Interactions

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PEGFILGRASTIM-6MGUnspecified nephritic syndrome
Severe
How does the disease interact with Adfill Injection 0.6 ml:
Glomerulonephritis can be caused by Adfill Injection 0.6 ml. Swelling of the face or ankles, blood or urine with a black colour, or a reduction in urine output are all symptoms.

How to manage the interaction:
If you have swelling of the face or ankles, dark-coloured urine, or blood in the urine, or a decrease in urine production while using Adfill Injection 0.6 ml, inform your doctor immediately as these may be signs and symptoms of glomerulonephritis (inflammation of tiny filters in the kidneys).
PEGFILGRASTIM-6MGMyeloid leukaemia
Severe
How does the disease interact with Adfill Injection 0.6 ml:
Colony stimulating agents predominantly promote neutrophil development, they may also potentially promote tumour growth, especially in myeloid malignancies. Patients with myeloid tumours should receive this medication therapy with caution.

How to manage the interaction:
Adfill Injection 0.6 ml should be used with caution in patients with myeloid tumors.
PEGFILGRASTIM-6MGOther disorders of white blood cells
Severe
How does the disease interact with Adfill Injection 0.6 ml:
Growth factors for neutrophil progenitor cells include Adfill Injection 0.6 ml. They should not be administered to anyone who have leukocytosis. Treatment should be stopped or the dosage lowered if excessive white blood cell counts develop while receiving CSF therapy.

How to manage the interaction:
Adfill Injection 0.6 ml is not recommended for leukocytosis (high white blood cell count) patients.

FAQs

Drug-Drug Interactions Checker List

  • CLADRIBINE
  • FILGRASTIM

Special Advise

  • Monitoring of (CBC) complete blood count during therapy is recommended.
  • While using Adfill Injection , do not get any immunizations or vaccinations unless your doctor has approved them.

Disease/Condition Glossary

Neutropenia: Neutropenia is characterized as a lower than the normal number of neutrophils (a type of white blood cell). White blood cells protect the body from infections. Without enough neutrophils, the body cannot fight bacteria, increasing the risk of many illnesses. Neutropenia can be caused by various conditions, including cancers like leukaemia, cancer treatment like radiotherapy, and infections like HIV or hepatitis.

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