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  3. Adhestop 25000IU Injection 5 ml

Written By Veda Maddala , M Pharmacy
Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy
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Composition :

HEPARIN-5000IU/ML

Manufacturer/Marketer :

VARENYAM HEALTHCARE PVT LTD

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Adhestop 25000IU Injection 5 ml

Adhestop 25000IU Injection 5 ml belongs to a class of drugs called anticoagulants or blood thinners. Adhestop 25000IU Injection 5 ml is primarily used to prevent and treat deep vein thrombosis (blood clots in leg veins), pulmonary embolism (blood clots in the lung), stroke, Transient ischaemic attack (TIA), and heart attacks.  Deep vein thrombosis is a medical condition in which blood clots form in deep veins usually in the legs. Pulmonary embolism is a condition in which a blood clot blocks the arteries in the lungs. A stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death. Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours. Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death.

Blood clots are formed to stop bleeding that occurs due to tissue injury. Though blood clots are useful to stop bleeding, they may be harmful when abnormally formed within blood vessels as they block blood vessels and inhibit blood flow to essential organs such as the brain, heart, or lungs. Adhestop 25000IU Injection 5 ml works by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot) preventing blood clot formation.

Adhestop 25000IU Injection 5 ml will be administered by a healthcare professional; do not self-administer. Some people may experience hemorrhage, thrombocytopenia (low platelets), hypersensitivity reactions, and elevations of liver enzyme (aminotransferase) levels. Most of these side effects of Adhestop 25000IU Injection 5 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Adhestop 25000IU Injection 5 ml or any other medicines, please tell your doctor. It is not known whether Adhestop 25000IU Injection 5 ml harms the baby or passes into breast milk in pregnancy and breastfeeding state. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Adhestop 25000IU Injection 5 ml. Adhestop 25000IU Injection 5 ml is not recommended for children below 2 months of age. If you have diabetes, kidney or liver problems, bleeding problems, or are aged above 60 years, inform your doctor before taking Adhestop 25000IU Injection 5 ml.

Uses of Adhestop 25000IU Injection 5 ml

Prevention of blood clots.

Directions for Use

Adhestop 25000IU Injection 5 ml will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Adhestop 25000IU Injection 5 ml is primarily used to prevent and treat blood clots by inhibiting the production of fibrin (a protein that binds platelets together and forms a clot). Adhestop 25000IU Injection 5 ml also reduces the risk of blood clots during surgeries (like heart surgery). Adhestop 25000IU Injection 5 ml is used as an anticoagulant in blood transfusion and in a dialysis procedure.

Storage

Store in a cool and dry place away from sunlight
Side effects of Adhestop 25000IU Injection 5 ml
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.

Drug Warnings

Use Adhestop 25000IU Injection 5 ml cautiously in conditions with increased risk of bleeding. Use of name contraindicated in patients with HIT - Heparin-induced thrombosis (the abnormal formation of blood clots inside a blood vessel) and HITT (heparin-induced thrombocytopenia and thrombosis) might occur. Monitoring of blood coagulation tests like platelet count and haematocrit should be done in all patients receiving Adhestop 25000IU Injection 5 ml. Patients should inform the doctor that they are receiving Adhestop 25000IU Injection 5 ml before any surgery is scheduled.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Adhestop 25000IU Injection 5 ml:
Taking Tenecteplase with Adhestop 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Adhestop 25000IU Injection 5 ml with Tenecteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you notice unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Taking Mifepristone with Adhestop 25000IU Injection 5 ml can increase the risk of negative side effects.

How to manage the interaction:
Taking Adhestop 25000IU Injection 5 ml with Mifepristone is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
HeparinBazedoxifene
Critical
How does the drug interact with Adhestop 25000IU Injection 5 ml:
When Adhestop 25000IU Injection 5 ml is taken with bazedoxifene the effects of Adhestop 25000IU Injection 5 ml are reduced by bazedoxifene.

How to manage the interaction:
Taking Bazedoxifene with Adhestop 25000IU Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Taking Ticlopidine with Adhestop 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Ticlopidine with Adhestop 25000IU Injection 5 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Taking Alteplase with Adhestop 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
Taking Adhestop 25000IU Injection 5 ml with Alteplase is not recommended as it can result in an interaction, it can be taken if a doctor has advised it. However, if you have unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
HeparinOritavancin
Critical
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Using Adhestop 25000IU Injection 5 ml with Oritavancin can make Adhestop 25000IU Injection 5 ml less effective as a therapy.

How to manage the interaction:
Adhestop 25000IU Injection 5 ml is not recommended within 120 hours (5 days) of taking oritavancin. Oritavancin can interfere with certain of the major coagulation tests used to assess Adhestop 25000IU Injection 5 ml's effectiveness and safety, it can be taken only if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Taking Dasatinib with Adhestop 25000IU Injection 5 ml can increase the risk and severity of bleeding.

How to manage the interaction:
Although there is a possible interaction between Adhestop 25000IU Injection 5 ml and Dasatinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor, if you experience bruising, dizziness, red or black, tarry stools, severe headache, and weakness. Do not stop using any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Coadministration of Ketorolac with Adhestop 25000IU Injection 5 ml can increase the risk of bleeding.

How to manage the interaction:
There may be a possibility of interaction between Ketorolac and Adhestop 25000IU Injection 5 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, call a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Co-administration of Cangrelor with Adhestop 25000IU Injection 5 ml can increase the risk of bleeding leading to serious blood loss.

How to manage the interaction:
Although there is a possible interaction between Adhestop 25000IU Injection 5 ml and Cangrelor, you can take these medicines together if prescribed by a doctor. However, if you have any unusual bleeding or bruising, dizziness, lightheadedness, red or black, tarry stools, coughing up or vomiting fresh or dried blood that looks like coffee grounds, severe headache, and weakness, you should seek immediate medical attention. Do not stop using any medications without a doctor's advice.
How does the drug interact with Adhestop 25000IU Injection 5 ml:
Taking Adhestop 25000IU Injection 5 ml with Streptokinase can increase the risk of bleeding.

How to manage the interaction:
Although taking Adhestop 25000IU Injection 5 ml and Streptokinase together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience any unusual bleeding or bruising, vomiting, blood in your urine or stools, headache, dizziness, or weakness, consult a doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Habit Forming

No

Therapeutic Class

ANTICOAGULANTS / ANTITHROMBOTICS. ANTICONVULSANTS

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

No, you are not recommended to take ibuprofen with Adhestop 25000IU Injection 5 ml as co-administration of these two medicines may increase the risk of bleeding more easily. However, please consult a doctor before taking other medicines with Adhestop 25000IU Injection 5 ml.

Yes, Adhestop 25000IU Injection 5 ml may increase potassium levels in the blood (hyperkalaemia), especially when given for a long period. Therefore, it is advised to inform your doctor if you are taking any medicines that increase potassium levels in the blood.

Yes, Adhestop 25000IU Injection 5 ml may cause bleeding. If you notice purple spots on the skin or unusual bruising, blood in urine, black tarry stools, unusual bleeding from gums or nose, please inform your doctor immediately as these are signs of bleeding more easily.

Yes, Adhestop 25000IU Injection 5 ml may cause allergic reactions such as fever, chills, difficulty in breathing, wheezing, blue shade to the lips, swelling of lips, and eyes. It is not necessary for everyone taking Adhestop 25000IU Injection 5 ml to experience an allergic reaction. However, if you notice any of these signs, please inform your doctor immediately.

Drug-Drug Interactions Checker List

  • SALICYLIC ACID
  • IBUPROFEN
  • INDOMETHACIN
  • PHENYLBUTAZONE
  • CELECOXIB
  • HYDROXYCHLOROQUINE
  • ABCIXIMAB
  • DIPYRIDAMOLE
  • DIGITALIS
  • TETRACYCLINE
  • NITROGLYCERIN

Special Advise

Regular blood tests are advised while taking Adhestop 25000IU Injection 5 ml to monitor prothrombin, platelets and coagulation time on regular basis.

Disease/Condition Glossary

Deep vein thrombosis (blood clots in legs) is a medical condition in which blood clots form in deep veins usually in the legs. The symptoms include leg pain or swelling.

Pulmonary embolism (blood clots in the lung) is a condition that occurs as the blood clots break and travel to the lungs from deep veins in the legs or other parts of the body. The symptoms of pulmonary embolism include chest pain, cough, and shortness of breath. 

Stroke is a condition where a blood clot restricts the flow of blood to your brain, causing brain cells to die and possibly resulting in permanent brain damage or death.

Transient ischaemic attack (TIA) is a condition also called 'mini-strokes', these have similar symptoms to a stroke, but the effects usually last less than 24 hours.

Heart attack is a condition where a blood clot blocks a blood vessel supplying your heart, starving it of oxygen and causing chest pain and sometimes death. Quick medication is advised to reduce the risk of serious conditions due to blood clots.

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