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Reviewed By Sunny S , MBBS

About Advastat F Tablet

Advastat F Tablet belongs to the class of lipid-lowering agent used to lowers an increased level of total cholesterol (TC) and triglyceride (TG) level. This prevents the risk of having any cardiovascular events like heart attack, stroke, and heart-related chest pain (angina) in the future. The blockage of the heart occurs due to the increased level of bad cholesterol (low-density lipoprotein -LDL and triglycerides - TG) which build-up of fat, cholesterol, and other waxy substances layers forming a plaque in the lining of the arteries wall (coronary arteries). This increases the chance of having a blood clot and heart attack in an individual.

Advastat F Tablet contains Rosuvastatin (statin) and Fenofibrate (fibric acid derivative). Rosuvastatin lowers the levels of raised lipids known as cholesterol and triglycerides in the blood and increasing the ‘good’ cholesterol (HDL) by blocking our body’s production of ‘bad’ cholesterol. It also improves your body’s ability to remove it from your blood. On the other hand, Fenofibrate works by lowering the level of triglyceride in the blood. 

You can take Advastat F Tablet with food or without food. It should be swallowed whole with a glass of water. Do not chew, bite, or break it. Your doctor will advise you how often you take your tablets based on your medical condition. In some cases, you may experience nausea, headache, abdominal pain, muscle pain, weakness, daytime drowsiness. Most of these side effects of Advastat F Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.    

It is important to have your cholesterol and triglyceride levels (lipid profile) checked regularly. This medicine is only one part of a treatment program which should also include a healthy low-fat diet, regular exercise, smoking cessation, moderation of alcohol intake, and weight reduction. You can eat normally while taking this medicine, but try to avoid foods that are high in fat. And also, please inform your doctor before starting Advastat F Tablet if you have kidney problems, are pregnant or breastfeeding, are diabetic (as you need to monitor your sugar level regularly).

rxMedicinePrescription drug

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

Uses of Advastat F Tablet

Hypertriglyceridemia, Hypercholesterolemia, and Mixed dyslipidaemia.

Medicinal Benefits

Advastat F Tablet is beneficial for the patients with Hypertriglyceridemia (high level of triglycerides), Hypercholesterolemia (high level of cholesterol), and Mixed Dyslipidaemia (elevated level of triglycerides – TG, low-density lipoprotein – LDL, and low level of high-density lipoprotein – HDL). Rosuvastatin first increases the LDL (bad cholesterol) on the liver cells for uptake and breakdown. Then, it stops the synthesis of very-low-density lipoprotein (VLDL) made by the liver to reduce the total number of bad cholesterols (LDL and VLDL). Fenofibrate works by increasing the enzyme (a natural substance) that breaks down fats or lipids present in the blood. Besides this, Fenofibrate also reduces the raised uric acid levels by increasing the excretion of uric acid through urination. It is also prescribed to diabetes patients with an increased level of lipid and cholesterol to minimize cardiovascular risks like heart attack, stroke, and heart-related chest pain (angina).

Side Effects of Advastat F Tablet

  • Nausea
  • Headache
  • Abdominal pain
  • Muscle pain (myalgia)
  • General weakness
  • Daytime drowsiness

Directions for Use

Swallow Advastat F Tablet as a whole with water; do not crush, break or chew it. It is better to take it at a fixed time.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Prolonged intake of statins is reported to cause severe musculoskeletal problems like myopathy and rhabdomyolysis. The most common adverse reactions associated with the use of Advastat F Tablet are muscle pain, muscle weakness, stomach upset, nausea, headache, and asthenia (general unexplained weakness). Elderly patients are at greater risk of having muscle problems so it should be given with caution and only after consulting the doctor. Rosuvastatin present in Advastat F Tablet is a pregnancy category X medicine (high risk to both pregnant mother and fetus). Hence, it should not be used by pregnant or lactating mothers. Advastat F Tablet also passes into the breast milk but its safety and efficiency are unclear, so its intake should be avoided by the nursing mother. The use of a Advastat F Tablet should be avoided in all kidney patients and to be taken with caution in all liver disease patients. The use of alcohol with Advastat F Tablet increases liver damage, so its use should be avoided. Advastat F Tablet contains fenofibrate which is contraindicated in gallstone patients, as there is an increased level of cholesterol in the bile leading to cholelithiasis.

Therapeutic Class

ANTILIPEMICS

Drug-Drug Interactions

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RosuvastatinLeflunomide
Severe
RosuvastatinSimeprevir
Severe

Drug-Drug Interactions

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RosuvastatinLeflunomide
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of leflunomide and Advastat F Tablet can increase the risk of developing liver problems.

How to manage the interaction:
Co-administration of Leflunomide and Advastat F Tablet can lead to an interaction, they can be taken together if prescribed by a doctor. However, if you experience fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, less desire to eat, fatigue, nausea, vomiting, abdominal pain, or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
RosuvastatinSimeprevir
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of Simeprevir and Advastat F Tablet can increase the blood levels of Advastat F Tablet and can increase the risk of side effects like liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Simeprevir and Advastat F Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinColchicine
Severe
How does the drug interact with Advastat F Tablet:
Coadministration of colchicine and Advastat F Tablet may increase the risk of conditions that affect your muscles and kidneys.

How to manage the interaction:
Taking Colchicine with Advastat F Tablet may possibly result in an interaction, but they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience abdominal discomfort, nausea, vomiting, diarrhea, back pain, weakness, or tingling or numbness in your hands and feet. Do not discontinue any medication without consulting your doctor.
RosuvastatinAmprenavir
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of Advastat F Tablet and amprenavir can increase the blood levels of Advastat F Tablet and can increase the risk of liver damage and rhabdomyolysis( breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Advastat F Tablet and Amprenavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinFenofibrate
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of Advastat F Tablet and Fenofibrate can increase the blood levels of Advastat F Tablet and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Advastat F Tablet and Fenofibrate can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinCiclosporin
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of ciclosporin with Advastat F Tablet can increase blood levels of Advastat F Tablet. This can increase the risk of developing side effects.

How to manage the interaction:
Co-administration of cyclosporine and Advastat F Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, light colour stools, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinDarunavir
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of Advastat F Tablet and Darunavir can increase the blood levels of Advastat F Tablet and can increase the risk of liver damage and rhabdomyolysis(breakdown of skeletal muscle tissue).

How to manage the interaction:
Co-administration of Advastat F Tablet and Darunavir can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, dark-colored urine, fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinClopidogrel
Severe
How does the drug interact with Advastat F Tablet:
Taking Advastat F Tablet with clopidogrel can increase the blood levels of Advastat F Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although taking clopidogrel together with Advastat F Tablet may result in an interaction, it can be taken if prescribed by your doctor. However, consult your doctor immediately if you experience chills, joint pain or swelling, skin rash, itching, nausea, vomiting, dark-colored urine, and/or yellowing of the skin or eyes. Do not discontinue any medication without consulting your doctor.
RosuvastatinGemfibrozil
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of Gemfibrozil and Advastat F Tablet may increase the risk or severity of side effects like muscle injury.

How to manage the interaction:
Co-administration of Gemfibrozil and Advastat F Tablet can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like muscle pain, tenderness, weakness, or dark-colored urine, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
RosuvastatinLenalidomide
Severe
How does the drug interact with Advastat F Tablet:
Co-administration of Advastat F Tablet with lenalidomide may increase the risk of a rare condition called rhabdomyolysis (breakdown of skeletal muscle tissue).

How to manage the interaction:
Although there is an interaction between lenalidomide and Advastat F Tablet, it can be taken if prescribed by a doctor. However, if you experience muscle pain, tenderness, or weakness, consult the doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CYCLOSPORINE
  • NIACIN
  • GEMFIBROZIL
  • LOPINAVIR
  • RITONAVIR
  • TIPRANAVIR
  • COUMADIN
  • WARFARIN
  • COLCHICINE

Diet & Lifestyle Advise

  • A low-fat diet is advised to lower levels of fat in the blood.
  • As a precautionary measure, you are recommended not to consume alcohol, or junk food items from outside, stick to freshly prepared home-cooked meals and take proper rest, for a speedy recovery.
  • And also try to replace most of your saturated fats with unsaturated fats can reduce total cholesterol and LDL cholesterol in a short span of time.
  • Foods like avocados, olive oil, fatty fish and nuts contain lots of heart-healthy unsaturated fats, so it’s beneficial to eat them regularly.
  • Regular exercise can make your heart strong and decrease your risk of a heart attack.

Habit Forming

No

Special Advise

  • You should have your lipid profile test including total cholesterol (TC), triglycerides (TG), LDL, HDL, VLDL and HDL done every 6 months to ensure whether Advastat F Tablet is working or not.
  • Your doctor may suggest certain tests to observe the enzyme levels during medication.

Disease/Condition Glossary

High cholesterol: Hyperlipidemia occurs when there are too many lipids (or fats), like cholesterol and triglycerides (TG). Hypercholesterolemia is a type of Hyperlipidemia in which there is excessive low-density lipoprotein - LDL (bad cholesterol) and low level of high-density lipoprotein - HDL (good cholesterol) in your blood. This condition increases the deposition of fats on the lining of heart arteries which increases the risk of heart blockage and other blood clot problems.  

Advastat F Tablet Substitute

Substitutes safety advice
  • Roseday-F 10 Tablet 10's

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    24.21per tablet
  • Rosuvas F 10 Tablet 15's

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    26.82per tablet
  • Rozavel F Tablet 10's

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    24.48per tablet
  • Novastat TG 10 Tablet 15's

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    31.56per tablet
  • Rozucor F 10 Tablet 15's

    by Others

    22.92per tablet
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