Aepio-40 Tablet 10's

₹99

(Inclusive of all Taxes)

₹14.8 Cashback (15%)

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Reviewed By Sunny S , MBBS

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Whats That

About Aepio-40 Tablet

Aepio-40 Tablet belongs to the class of drugs known as Proton pump inhibitor which reduces the amount of acid your stomach makes. It treats gastroesophageal reflux disease (GERD), stomach ulcers and Zollinger Ellison syndrome (overproduction of acid due to pancreatic tumour).

Aepio-40 Tablet helps in reducing the stomach acid by blocking the actions of an enzyme (H+/K+ ATPase or gastric proton pump). This proton pump lies in the cells of the stomach wall responsible for the release of gastric acid secretion damaging tissues in the food pipe, stomach, and duodenum. Aepio-40 Tablet prevents the release of stomach acid and relieves symptoms of food pipe lining inflammation (esophagitis), and gastroesophageal reflux disease (GERD), or heartburn.

Take Aepio-40 Tablet 1-2hours prior food. You are advised to take Aepio-40 Tablet for as long as your doctor has prescribed it for you depending on your medical condition. An adult taking Aepio-40 Tablet might have common side effects like headache, diarrhoea, nausea, abdominal pain, vomiting, flatulence, dizziness, and arthralgia (joint pain). In the case of children taking Aepio-40 Tablet might report upper respiratory tract infections (URI), headache, fever, diarrhoea, vomiting, rash, and abdominal pain. These side effects are temporary and may get resolve after some time however if this side persists contact the doctor.

Aepio-40 Tablet is safe for pregnant and breastfeeding mothers but should be taken only after consulting a doctor. Tell your doctor if you have stomach or intestinal cancer, liver problem, allergic to Aepio-40 Tablet , or will have an endoscopy in the future. Prolonged intake of Aepio-40 Tablet may cause deficiency of Vitamin B12 and low level of calcium, magnesium, and Vitamin D leading to osteoporosis.

Uses of Aepio-40 Tablet

Hyperacidity, Heartburn, Stomach ulcer, Zollinger-Ellison syndrome

Directions for Use

Tablet/capsule: Swallow it as a whole with water; do not crush, break or chew it.Suspension/Syrup: Shake the bottle well before use. Check the label for directions and take Aepio-40 Tablet in doses as prescribed by your doctor with the help of a measuring cup.Powder/granules: Check the label for directions before use. Mix the powder/granules in water, mix well and drink immediately.

Medicinal Benefits

Aepio-40 Tablet is effective at healing erosive esophagitis (inflammation of food pipe), relieving symptoms of gastroesophageal reflux disease (heartburn), and Zollinger-Ellison syndrome. Aepio-40 Tablet works by irreversibly blocking the proton pump gate (which secretes stomach acid). It can be prescribed to all age groups including special populations like the elderly, pregnant, lactating mothers, kidney, and liver disease patients. Usually, no dosage adjustment is required for these groups.

Storage

Keep out of the sight and reach of children.

Drug Warnings

You should avoid taking Aepio-40 Tablet if you are allergic to Aepio-40 Tablet or proton pump inhibitors, have gastric cancer, liver disease, low magnesium level (osteoporosis), low vitamin B12, pregnant or planning for pregnancy, and breastfeeding mothers. Aepio-40 Tablet may interact with a blood thinner (warfarin), antifungal (ketoconazole), anti-HIV drug (atazanavir, nelfinavir), iron supplements, ampicillin antibiotic, anti-cancer drug (methotrexate). Let your doctor know if you are taking these medicines. Prolonged intake of Aepio-40 Tablet may cause lupus erythematosus (an inflammatory condition in which the immune system attacks its own tissues), Vitamin B12, and magnesium deficiency. Intake of Aepio-40 Tablet may mask the symptom of gastric cancer, so if you have any severe stomach pain or gastric bleeding (blood in mucous or stool) immediately consult the doctor.

Drug-Drug Interactions

EsomeprazoleRilpivirine

Critical

EsomeprazoleClopidogrel

Severe

Drug-Drug Interactions

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EsomeprazoleRilpivirine

Critical

How does the drug interact with Aepio-40 Tablet:
Aepio-40 Tablet may reduce rilpivirine absorption and blood levels, making the medicine less effective against HIV.

How to manage the interaction:
Although taking Aepio-40 Tablet with Rilpivirine can possibly result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if your symptoms do not improve. Do not discontinue using any medications without consulting a doctor.

EsomeprazoleClopidogrel

Severe

How does the drug interact with Aepio-40 Tablet:
Coadministration of Clopidogrel with Aepio-40 Tablet may reduce the effectiveness of clopidogrel.

How to manage the interaction:
Taking clopidogrel and Aepio-40 Tablet together possibly has an interaction, but you can take these medications together if your doctor has advised it. Do not stop using any medications without talking to your doctor.

EsomeprazoleNelfinavir

Severe

How does the drug interact with Aepio-40 Tablet:
Taking nelfinavir with Aepio-40 Tablet may decrease the effects of nelfinavir.

How to manage the interaction:
Although taking Aepio-40 Tablet and Nelfinavir can possibly result in an interaction, they can be taken together if prescribed by your doctor. Do not stop taking any medications without consulting your doctor.

EsomeprazoleCitalopram

Severe

How does the drug interact with Aepio-40 Tablet:
Combining Aepio-40 Tablet with Citalopram can increase the risk of irregular heart rhythm. .

How to manage the interaction:
Co-administration of Aepio-40 Tablet with Citalopram can possibly result in an interaction, but it can be taken if your doctor has advised it. If you're having any symptoms like irregular heart rhythm, dizziness, fainting, or shortness of breath, it's important to contact your doctor immediately. Do not stop using any medications without a doctor's advice.

EsomeprazoleErlotinib

Severe

How does the drug interact with Aepio-40 Tablet:
Coadministration of erlotinib and Aepio-40 Tablet can reduce effects of erlotinib.

How to manage the interaction:
Taking Erlotinib and Aepio-40 Tablet together is generally avoided as it can possibly result in an interaction. It can be taken if your doctor has advised it. Do not stop using any medications without first talking to your doctor.

EsomeprazoleDasatinib

Severe

How does the drug interact with Aepio-40 Tablet:
Using Dasatinib together with Aepio-40 Tablet may decrease the levels of Dasatinib.

How to manage the interaction:
Although taking Aepio-40 Tablet together with Dasatinib can result in an interaction, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.

EsomeprazoleTacrolimus

Severe

How does the drug interact with Aepio-40 Tablet:
Taking tacrolimus with Aepio-40 Tablet may significantly increase the blood levels of tacrolimus, which can lead to an increased risk of side effects.

How to manage the interaction:
Although taking Aepio-40 Tablet with Tacrolimus can result in an interaction, they can be taken together if prescribed by your doctor. However, contact a doctor immediately if you experience irregular heartbeat, blurring of vision, fever, chills, or muscle spasms. Do not discontinue any medications without consulting a doctor.

EsomeprazoleGefitinib

Severe

How does the drug interact with Aepio-40 Tablet:
Taking gefitinib with Aepio-40 Tablet may reduce the effectiveness of gefitinib.

How to manage the interaction:
Although taking Aepio-40 Tablet and Gefitinib together can possibly result in an interaction, they can be taken together if prescribed by your doctor. It is recommended to take Gefitionib 12 hours before or after taking Aepio-40 Tablet. Do not stop taking any medications without consulting a doctor.

EsomeprazoleMethotrexate

Severe

How does the drug interact with Aepio-40 Tablet:
Co-administration of methotrexate and Aepio-40 Tablet can increase the blood levels and side effects of methotrexate.

How to manage the interaction:
Although taking Aepio-40 Tablet with Methotrexate can result in an interaction, they can be taken together if prescribed by a doctor. However, contact your doctor if you experience headache, dizziness, nausea and vomiting. Do not discontinue any medications without consulting a doctor.

EsomeprazoleDacomitinib

Severe

How does the drug interact with Aepio-40 Tablet:
Aepio-40 Tablet can make Dacomitinib less effective by reducing its absorption and lowering its concentration in the blood.

How to manage the interaction:
Co-administration of Aepio-40 Tablet with Dacomitinib can result in an interaction, but it can be taken if your doctor has advised it. Do not stop using any medications without talking to your doctor.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Avoid intake of acid or heartburn triggering foods or drinks like onions, peppermint, chocolate, caffeinated beverages, citrus fruits or juices, tomatoes and high-fat and spicy foods.
Before going to sleep try to raise your bedhead so that your head and chest are higher than your feet. Do not use piles of pillows, instead, one raised block is fine. This will not allow the stomach acid to backflow through your food pipe.
Avoid taking alcohol and smoking cigarette. Alcohol can raise the level of production of stomach acid leading to heartburn and acid reflux. On the other hand, nicotine smoking damages the valve (sphincter) which prevents backflow of the stomach acid back into the food pipe.
Include high fibre containing foods, berries, cherries, leafy green veggies (kale, spinach) and black peppers in your meal. These foods are full of antioxidant, calcium and vitamin B 12 that can help cope with the long term effects of the medicine. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess stomach acid production. Cranberry juice can be beneficial in the peptic ulcer and H Pyroli infection.
Avoid regular sitting continuously, as it can increase stomach acid production. Try to take a break of 5 minutes in 1 hour by brisk walking or stretching.

Side Effects of Aepio-40 Tablet

In adults

Headache
Diarrhoea
Nausea
Abdominal pain
Vomiting
Flatulence
Dizziness
Arthralgia (joint pain)

In Children

Upper respiratory tract infections (URI)
Headache
Fever
Diarrhoea
Vomiting
Rash
Abdominal pain

Habit Forming

No

Therapeutic Class

ANTACIDS

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Aepio-40 Tablet work?

Aepio-40 Tablet is a proton pump inhibitor (PPI), which is a type of medication. Proton pumps are enzymes found in the stomach lining that aid in the production of acid needed for digestion. Esomeprazole impairs the function of proton pumps. This decreases the quantity of acid produced by the stomach.

What are the long term effects of Aepio-40 Tablet ?

Prolonged intake of Aepio-40 Tablet may lead to atrophic gastritis (inflammation of stomach cells), Vitamin B12 deficiency and weakening of bones or osteoporosis (loss of calcium, magnesium and vitamin D). Your doctor may prescribe calcium, vitamin D or haemoglobin enhancing medications to cope with long term side effects.

Does Aepio-40 Tablet treats gastric bleeding?

No. Aepio-40 Tablet prevents excess production of stomach acid causing acid reflux and heartburn. If blood is coming in your stool or mucous immediately contact the doctor.

Does Aepio-40 Tablet interfere or affect laboratory test reports?

Yes. Aepio-40 Tablet can alter certain medical tests like neuroendocrine tumours (secretin stimulation test), and urine screening tests for tetrahydrocannabinol (THC). So before undergoing such diagnostics test contact your doctor.

What if I take too much Aepio-40 Tablet ?

It is very unlikely that taking one or two extra doses by accident will cause any problems. However, you should check with your doctor if you have taken too much and have are feeling sweaty, have a fast heartbeat, are feeling sleepy.

Will Aepio-40 Tablet affect my fertility?

There's no firm evidence to suggest that taking Aepio-40 Tablet will reduce fertility in either men or women. However, speak to your doctor if you're trying to get pregnant and do as advised.

Is there any food or drink I need to avoid while taking Aepio-40 Tablet ?

You can eat and drink normally while taking Aepio-40 Tablet . However, you should avoid foods that seem to make your indigestion worse, such as rich, spicy and fatty foods. You should also cut down on caffeinated drinks, such as tea, coffee and cola, as well as alcohol.

Are gas and acidity same thing?

No. Gas and acidity are two different common discomforts. Acidity is caused when improper functioning of the valve (sphincter) is located at the junction of the stomach and food pipe. As a result stomach acid backflows and enters the upper part of the food pipe causing heartburn. On the other hand, gas is the result of the digestion of the food and drinks eliminating gases like carbon dioxide, hydrogen, nitrogen, methane, etc. from the body.

Drug-Drug Interactions Checker List

CLOPIDOGREL
WARFARIN
KETOCONAZOLE
VORICONAZOLE
ITRACONAZOLE
POSACONAZOLE
ATAZANAVIR
NELFINAVIR
RILPIVIRINE
AMPICILLIN
RIFAMPICIN
DIGOXIN
METHOTREXATE

Special Advise

Prolonged intake of Aepio-40 Tablet may be associated with increased risk of Clostridium difficile associated diarrhea, magnesium and Vitamin B-12 deficiency (increased risk of bone fracture), atrophic gastritis (inflammed lining of stomach), and acute interstitial nephritis (inflammed cells of kidney).

Disease/Condition Glossary

Normally a thick layer of mucous protects the stomach against its own acid secretion. But, in long run, it gets eroded by excessive stomach acid production leading to complications like GERD, peptic ulcer, and Zollinger Ellison syndrome. Gastroesophageal reflux disease (GERD) is a gastrointestinal disorder that occurs when stomach acid frequently flows back into the food pipe (esophagus). This backflow (acid reflux) irritates the food pipe that causes heartburn. On the other hand, peptic ulcer is a painful condition followed by the development of sores or ulcers in the stomach lining or duodenum (first part of the small intestine) (the duodenum). Zollinger Ellison syndrome is a rare condition in which a gastrin-secreting tumor of the pancreas causes excessive acid production leading to peptic ulcers.