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Reviewed By Sureshvarma D , MPharma
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Composition

EVEROLIMUS

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About AFINITOR 10 MG TABLET 10'S

AFINITOR 10 MG TABLET 10'S belongs to the group of medicine called ‘anti-cancer’. It is primarily used to treat breast cancer, pancreatic cancer, lung cancer and kidney cancer. Breast cancer is a type of cancer that develops in breast cells stimulated by the female sex hormone known as estrogen. Pancreatic cancer is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices that help break down food and the hormones which help in controlling blood sugar levels. Lung cancer is the uncontrolled growth of abnormal cells in one or both lungs. 

AFINITOR 10 MG TABLET 10'S contains 'Everolimus' which belongs to the group of medicines known as 'kinase inhibitors'. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells.

Take AFINITOR 10 MG TABLET 10'S as prescribed by your doctor. You are advised to take AFINITOR 10 MG TABLET 10'S for as long as your doctor has prescribed it for you depending on your medical conditions. You may experience weakness, infection, sinus inflammation, cough, diarrhea, fever, fatigue, otitis media (infection of the ear), stomatitis (Inflammation of the mouth) and upper respiratory tract infection. Most of these side effects of AFINITOR 10 MG TABLET 10'S do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

To treat your condition effectually, continue taking AFINITOR 10 MG TABLET 10'S for as long as your doctor has prescribed. If you are known to be allergic to AFINITOR 10 MG TABLET 10'S or any other medicines, please tell your doctor. Do not take AFINITOR 10 MG TABLET 10'S if you are pregnant or planning for pregnancy as AFINITOR 10 MG TABLET 10'S may harm the unborn baby. AFINITOR 10 MG TABLET 10'S should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. AFINITOR 10 MG TABLET 10'S causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Uses of AFINITOR 10 MG TABLET 10'S

Breast cancer, pancreatic cancer, lung cancer and kidney cancer.

Directions for Use

Take AFINITOR 10 MG TABLET 10'S with or without food as advised by the doctor. Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

AFINITOR 10 MG TABLET 10'S is indicated to the patients dealing with breast cancer, pancreatic cancer, lung cancer, kidney cancer and stomach/ intestinal cancer. Cancer of this type tends to spread quickly in other parts of the body. AFINITOR 10 MG TABLET 10'S travels through the bloodstream and effectively destroys cancerous cells and other parts of the body. It works by decreases the activity of the immune system of the body and prevents rejection of the transplanted organ. It works by stopping the action of an abnormal protein that causes the multiplication of cancerous cells. In this way, it stops the spread of cancerous cells. Besides this, it is also effective in people with genetic disorders to treat some types of tumors in the brain or kidney.

Storage

Store in a cool and dry place away from sunlight

Side Effects of AFINITOR 10 MG TABLET 10'S

  • Tiredness
  • Breathlessness
  • Dizziness
  • Headache
  • Loss of appetite
  • Infection
  • Mouth ulcers 
  • Sinus inflammation
  • Cough
  • Diarrhea
  • Fever
  • High level of sugar in the blood (hyperglycemia)
  • Signs of low level of red blood cells (anemia) 
  • Otitis media (infection of the ear)
  • Stomatitis (Inflammation of the mouth)
  • Upper respiratory tract infection.
  • Swelling of arms, hands, feet, and ankles

Drug Warnings

If you are known to be allergic to AFINITOR 10 MG TABLET 10'S or any other medicines, please tell your doctor. AFINITOR 10 MG TABLET 10'S should not be taken in the conditions like liver disease, diabetes and high level of cholesterol. Do not take AFINITOR 10 MG TABLET 10'S if you have recent surgery, infection and hepatitis B. AFINITOR 10 MG TABLET 10'S may weaken your immune system, inform your doctor before taking AFINITOR 10 MG TABLET 10'S. AFINITOR 10 MG TABLET 10'S may also impair your kidney function. Therefore, monitor your kidney function regularly while taking AFINITOR 10 MG TABLET 10'S. AFINITOR 10 MG TABLET 10'S may cause cough, fever and shortness of breathing, thereby inform your doctor while taking your AFINITOR 10 MG TABLET 10'S. AFINITOR 10 MG TABLET 10'S may cause skin cancer, if you observe night sweating, weight loss, or change in color and size of the mole inform your doctor. Do not take AFINITOR 10 MG TABLET 10'S if you are pregnant or planning for pregnancy as AFINITOR 10 MG TABLET 10'S may harm the unborn baby. AFINITOR 10 MG TABLET 10'S should not be taken by breastfeeding mothers as it may cause harm to the newborn baby. AFINITOR 10 MG TABLET 10'S causes tiredness, thus, it is advisable not to drive unless you are alert. Elderly people are more sensitive to medicine so they may adjust the dosage according to their condition.

Drug-Drug Interactions

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EverolimusErythromycin
Severe
EverolimusTeriflunomide
Severe

Drug-Drug Interactions

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EverolimusErythromycin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Erythromycin may considerably raise Afinitor 10 Mg Tablet levels in the blood. This can increase the risk or severity of side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although taking erythromycin and Afinitor 10 Mg Tablet together can result in an interaction, they can be taken together if prescribed by a doctor. However, if you experience any unusual symptoms contact a doctor immediately. Do not stop using any medications without talking to a doctor.
EverolimusTeriflunomide
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
When Afinitor 10 Mg Tablet is used with teriflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although there is a possible interaction between Afinitor 10 Mg Tablet and Teriflunomide, you can take these medicines together if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusNelfinavir
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Taking Afinitor 10 Mg Tablet with nelfinavir can considerably raise blood levels of Afinitor 10 Mg Tablet, increasing the risk of serious side effects (pneumonitis - lung inflammation, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although taking Afinitor 10 Mg Tablet and Nelfinavir together can cause an interaction, it can be taken if a doctor has suggested it. Do not discontinue any medications without a doctor's advice.
EverolimusLeflunomide
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
When Afinitor 10 Mg Tablet is used with leflunomide, the likelihood or severity of infection may increase.

How to manage the interaction:
Although taking Leflunomide and Afinitor 10 Mg Tablet together can cause an interaction, it can be taken if a doctor has suggested it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
EverolimusMethotrexate
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Coadministration of Afinitor 10 Mg Tablet with Methotrexate can increase the risk or severity of kidney disorders.

How to manage the interaction:
Taking Afinitor 10 Mg Tablet with Methotrexate together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not stop using any medications without talking to a doctor.
EverolimusMetrizamide
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Injections of metrizamide and related contrast agents can occasionally cause kidney damage, and mixing them with other medication that might adversely harm the kidney, such as Afinitor 10 Mg Tablet, may enhance the risk.

How to manage the interaction:
Although taking Afinitor 10 Mg Tablet and Metrizamide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor immediately. Drink lots of fluid after the procedure to stay hydrated and to flush the contrast agent out of your kidneys. Do not stop using any medications without talking to a doctor.
EverolimusAprepitant
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Coadministration of Afinitor 10 Mg Tablet with Aprepitant blood levels may considerably increase the blood level of the aprepitant, which increases the severity of serious side effects (pneumonitis - inflammation of the lungs, infection, mouth ulcers, anemia, or bleeding).

How to manage the interaction:
Although co-administration of Aprepitant and Afinitor 10 Mg Tablet can lead to an interaction, it can be taken if prescribed by a doctor. Consult a doctor if you suffer any symptoms, including bleeding, anemia, oral ulcers, infection, lung problems (shortness of breath, persistent cough, tiredness). Without consulting a doctor, never stop taking medicines.
EverolimusAnakinra
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
When Afinitor 10 Mg Tablet is coupled with Anakinra, the breakdown of it can be enhanced.

How to manage the interaction:
Although there is a possible interaction between Anakinra and Afinitor 10 Mg Tablet, you can take these medicines together if prescribed by a doctor. Do not discontinue any medications without a doctor's advice.
EverolimusEtodolac
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Afinitor 10 Mg Tablet can cause kidney problems, and taking it with etodolac, can enhance the risk.

How to manage the interaction:
There may be a possibility of interaction between Etodolac and Afinitor 10 Mg Tablet, but it can be taken if prescribed by a doctor. However, consult a doctor if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm. Do not discontinue any medications without a doctor's advice.
EverolimusFosphenytoin
Severe
How does the drug interact with Afinitor 10 Mg Tablet:
Taking Afinitor 10 Mg Tablet and Fosphenytoin may reduce the blood levels of Afinitor 10 Mg Tablet, which may make it less effective in treating the condition.

How to manage the interaction:
Although there is a possible interaction between Afinitor 10 Mg Tablet and Fosphenytoin, you can take these medicines together if prescribed by a doctor. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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EVEROLIMUSGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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EVEROLIMUSGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice

How to manage the interaction:
Taking Afinitor 10 Mg Tablet with grapefruit juice can raise blood levels and enhance the effects of Afinitor 10 Mg Tablet. Since the co-administration of Afinitor 10 Mg Tablet along with grapefruit juice can lead to an interaction, You should not consume grapefruit juice or eat grapefruits while taking Afinitor 10 Mg Tablet.

Diet & Lifestyle Advise

  • Avoid smoking and alcohol consumption.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yogurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs and spices in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep, rest well.
  • Performing yoga and other relaxation techniques may also improve physical and mental health and may reduce your stress levels.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

AFINITOR 10 MG TABLET 10'S Substitute

Substitutes safety advice
  • Volantis 5Mg Tablet 10'S

    by AYUR

    1025.00per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • KETOCONAZOLE
  • ITRACONAZOLE
  • VORICONAZOLE
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • ERYTHROMYCIN
  • RITONAVIR
  • EFAVIRENZ
  • RAMIPRIL
  • VERAPAMIL
  • DILTIAZEM
  • DRONEDARONE
  • IMATINIB
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL
  • FLUCONAZOLE

Special Advise

  • AFINITOR 10 MG TABLET 10'S should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking AFINITOR 10 MG TABLET 10'S.
  • Do not have immunizations/vaccinations without a doctor's advice.
  • Avoid contact with people who have recently received live vaccines.

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells that are stimulated by a female sex hormone called estrogen. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), in the fatty tissue or the fibrous connective tissue within the breast. The tumor cells invade other healthy breast cells and can travel to lymph nodes which are a primary pathway for the cancer cells to move to other parts of the body. 

Lung cancer: It happens when cells in the lung begin to grow in an uncontrolled manner. The most common form of lung cancer is non-small cell lung cancer (NSCLC). It happens when cells that form the lining of the lung start growing uncontrollably. Persons who smoke are at high risk of lung cancer. A common symptom of lung cancer is a cough that does not go easily followed by shortness of breath. Cancerous cells of the lung spread off and travel through the bloodstream to distant regions of the body and grow.

Pancreatic cancer: It is described as a cancerous growth in the pancreas which normally begins in the cells that generate the juices. Juices are produced by the pancreas ( a gland present behind your stomach) help in the breakdown of food and hormones which help in controlling blood sugar levels.

Kidney cancer: Kidneys are the organs on either side of your backbone directly above your waist. The tubes present inside clean and filter your blood, taking out waste foods and making urine. Kidney cancer produces in the lining of tiny tubes inside your kidneys.

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