Alphagan Z Opthalmic Solution 5 ml

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Written By Santoshini Reddy G , M Pharmacy

Reviewed By Hari Kumar , MBBS

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Whats That

About Alphagan Z Opthalmic Solution 5 ml

Alphagan Z Opthalmic Solution 5 ml is indicated to lower the intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Glaucoma is an eye disease that causes damage to the optic nerve and results in reduced vision. Ocular hypertension is increased pressure in the eye due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow).

Alphagan Z Opthalmic Solution 5 ml contains Brimonidine tartrate (alpha-2 adrenergic receptor agonists) and Stabilized oxychloro complex (preservative). Brimonidine tartrate decreases the production of aqueous humour, thereby helps lower the increased pressure in the eye. Stabilized oxychloro complex acts as a preservative.

You are advised to use Alphagan Z Opthalmic Solution 5 ml for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, you may experience certain common side effects such as blurred vision, eye redness, discomfort, drowsiness and dry mouth. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Consult a doctor if you are pregnant or breastfeeding. Alphagan Z Opthalmic Solution 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Alphagan Z Opthalmic Solution 5 ml might cause drowsiness; so, drive only if you are alert. Avoid touching the tip of the dropper as it may contaminate the contents. Keep your doctor informed about your health condition and the medicines you are taking to prevent any side effects/interactions.

Uses of Alphagan Z Opthalmic Solution 5 ml

Open-angle glaucoma or ocular hypertension

Directions for Use

Lie down and tilt your head backwards. Pull your lower eyelid gently with your index finger to form a pocket. Instil the number of drops advised by the doctor into the pocket of the lower eyelid. Close your eyes for 1-2 minutes.

Medicinal Benefits

Alphagan Z Opthalmic Solution 5 ml contains Brimonidine tartrate and Stabilized oxychloro complex. Alphagan Z Opthalmic Solution 5 ml is indicated for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Brimonidine tartrate belongs to a group of medicines called alpha-2 adrenergic receptor agonists. It helps decrease the production of aqueous humour, thereby helps lower the increased pressure in the eye. Stabilized oxychloro complex acts as a preservative.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Alphagan Z Opthalmic Solution 5 ml if you are allergic to any of its components, if you are taking monoamine oxidase inhibitors or tricyclic antidepressants. Inform your doctor if you have liver problems, narrow-angle glaucoma, dry eyes, cornea problems, coronary heart disease, depression, poor or disturbed blood circulation. Consult a doctor if you are pregnant or breastfeeding. Alphagan Z Opthalmic Solution 5 ml is not recommended for children below 18 years as safety and effectiveness have not been established. Alphagan Z Opthalmic Solution 5 ml might cause drowsiness, abnormal/blurred vision; so, drive only if you are alert.

Drug-Drug Interactions

BrimonidineBrivaracetam

Moderate

Drug-Drug Interactions

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BrimonidineBrivaracetam

Moderate

How does the drug interact with Alphagan Z Opthalmic Solution 5 ml:
Alphagan Z Opthalmic Solution 5 ml may be absorbed into the bloodstream and occasionally produce central nervous system side effects such as dizziness, drowsiness, and difficulty concentrating. Concomitant use of brivaracetam with Alphagan Z Opthalmic Solution 5 ml may increase the risk of these side effects.

How to manage the interaction:
Although there is an interaction brivaracetam can be taken with Alphagan Z Opthalmic Solution 5 ml if prescribed by the doctor. Consult the prescriber if you notice dizziness, drowsiness, and difficulty concentrating.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Wash your hands regularly. Avoid touching the eyes with dirty hands.
Include fresh fruits and vegetables in your diet.
Avoid smoking and alcohol consumption.
Avoid intake of baked foods such as cakes, cookies, doughnuts or fried items such as French fries and stick margarine as these foods may worsen glaucoma and damage the optic nerve.
Cut down your coffee intake as it may increase pressure in the eye. Replace coffee with green tea.
Avoid exercises such as any position where the head is lower than the body, like an inverted yoga pose, as it may increase pressure in the eye. Doing selective exercises is advised for glaucoma patients.

Habit Forming

No

Therapeutic Class

OPHTHALMOLOGIC AGENTS

Author Details

Written By

Santoshini Reddy G

M Pharmacy

Reviewed By

Hari Kumar

MBBS

Last Updated

Jul 8, 2025 | 9:40 AM IST

We provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Alphagan Z Opthalmic Solution 5 ml work?

Alphagan Z Opthalmic Solution 5 ml decreases the production of aqueous humour, thereby helps lower the increased pressure in the eye.

Can I stop using Alphagan Z Opthalmic Solution 5 ml on my own?

Do not stop using Alphagan Z Opthalmic Solution 5 ml without consulting your doctor. Continue using Alphagan Z Opthalmic Solution 5 ml for as long as your doctor has prescribed it to you to treat your condition effectually. Consult the doctor if you experience any difficulty while using Alphagan Z Opthalmic Solution 5 ml.

Does Alphagan Z Opthalmic Solution 5 ml cause blurred vision?

Alphagan Z Opthalmic Solution 5 ml might cause blurred or abnormal vision. So, avoid driving or operating machinery until your vision is clear to prevent any mishappening.

Can I wear contact lens while using Alphagan Z Opthalmic Solution 5 ml?

Do not wear contact lens while using Alphagan Z Opthalmic Solution 5 ml. Remove contact lenses before using Alphagan Z Opthalmic Solution 5 ml and put them back 15minutes after using Alphagan Z Opthalmic Solution 5 ml.

Does Alphagan Z Opthalmic Solution 5 ml cause dry mouth?

Dry mouth could be a side-effect of Alphagan Z Opthalmic Solution 5 ml. Limiting caffeine intake, avoiding smoking and mouthwashes containing alcohol; drinking water regularly, and chewing sugar-free gum/candy might stimulate saliva and prevent drying of the mouth.

Can I use other eye medications with Alphagan Z Opthalmic Solution 5 ml?

Alphagan Z Opthalmic Solution 5 ml can be used with other eye medications if prescribed by the doctor. However, maintain a gap of 5-10minutes between Alphagan Z Opthalmic Solution 5 ml and other eye medications.

Disease/Condition Glossary

Glaucoma: It is an eye condition that causes damage to the optic nerve (essential for good vision) due to abnormally increased pressure in the eye. If it is not treated in time, it may cause blindness.

Ocular hypertension: It is a condition caused due to poor drainage of aqueous humour (fluid in the eye that maintains normal pressure by its continuous flow). This leads to a build-up of excess fluid in the eye resulting in increased pressure inside the eye without any damage to the optic nerve. If ocular hypertension is not controlled, it may lead to glaucoma.

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Alphagan Z Opthalmic Solution 5 ml

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Drug-Drug Interactions

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FAQs

How does Alphagan Z Opthalmic Solution 5 ml work?

Can I stop using Alphagan Z Opthalmic Solution 5 ml on my own?

Does Alphagan Z Opthalmic Solution 5 ml cause blurred vision?

Can I wear contact lens while using Alphagan Z Opthalmic Solution 5 ml?

Does Alphagan Z Opthalmic Solution 5 ml cause dry mouth?

Can I use other eye medications with Alphagan Z Opthalmic Solution 5 ml?