ALRUBICIN 100MG INJECTION

Written By Lakshmithulasi Yarragunta , Pharm-D (PB)

Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

MRP ₹2540

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₹381.0 Cashback (15%)

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Whats That

About ALRUBICIN 100MG INJECTION

ALRUBICIN 100MG INJECTION is an anti-cancer medicine that is used in conjunction with other drugs to treat breast cancer in people who have had tumor removal surgery. ALRUBICIN 100MG INJECTION is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer (abnormal growth in the cells of the breast).

ALRUBICIN 100MG INJECTION contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

ALRUBICIN 100MG INJECTION may cause certain side effects such as nausea, headache, abdominal pain, loss of appetite, vomiting, dizziness, mouth sores, tiredness, back pain, diarrhoea, and pain at the site of injection. Most of these side effects do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor. A trained healthcare doctor will administer ALRUBICIN 100MG INJECTION. So, do not self-administer. Your doctor will decide the dose of the medicine based on your health condition.

ALRUBICIN 100MG INJECTION should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines, and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (eg, Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. ALRUBICIN 100MG INJECTION is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. ALRUBICIN 100MG INJECTION is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF.

Uses of ALRUBICIN 100MG INJECTION

Breast Cancer

Directions for Use

A trained healthcare professional will administer ALRUBICIN 100MG INJECTION. Hence, do not self-administer.

Medicinal Benefits

ALRUBICIN 100MG INJECTION contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis. It is used as adjuvant chemotherapy in women with axillary lymph nodes with involvement resection of breast cancer.

Storage

Keep ALRUBICIN 100MG INJECTION out of the sight and reach of children.

Side effects of Alrubicin 100mg Injection

Hair Loss

Eat protein-rich foods like fish, poultry, eggs, and legumes.
Include foods with minerals and vitamins essential for hair health.
Join a support group to connect with others experiencing hair loss.
Openly discuss your feelings about hair loss.
Consider covering up with wigs, hats, or scarves.
Be patient and avoid seeking miracle cures.

Nausea

Overcome Medication-Induced Nausea: A 9-Step Plan

Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
Divide your daily food intake into smaller, more frequent meals to reduce nausea.
Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
Use ginger (tea, ale, or candies) to help relieve nausea.
Get adequate rest and also avoid strenuous activities that can worsen nausea.
Talk to your doctor about taking anti-nausea medication if your nausea is severe.
Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Vomiting

To prevent, manage, and treat Constipation caused by medication usage, follow these steps:

Preventing Vomiting (Before it Happens)
Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
Having a small meal before taking your medication can help reduce nausea and vomiting.
Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
Managing Vomiting (If it Happens)
Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
What to Do if Vomiting Persists
Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Low White Blood Cell Count

Boost your immunity by including immune rich foods in your diet and always remember to stay hydrated.
Get sufficient sleep and manage stress which helps in improving white blood cell count.
Consult your doctor for an effective treatment to improve the blood cell count and get regular body check up to monitor changes in the count.
Try to prevent the factors that cause a decrease in the white blood cells that may lead to impaired immunity.

Abnormal Cessation Of Menstrual Periods

Eat a healthy balanced diet.
Reduce stress with relaxation techniques such as yoga or meditation.
Keep track of your menstrual cycle any irregularities.
Have regular check ups to exclude other health problems.
Exercise but do not exercise to the extent of overheating.
Hydrate well, eat well (particularly iron and vitamins).

Anemia

Include iron-rich foods like dark leafy vegetables, lean red meat, legumes and fish in your diet.
Consume vitamin C-rich foods as they aid iron absorption.
Limit tea, cocoa, and coffee as these can slow iron absorption.
Exercise regularly; however, do not overdo it.

Inflammation Of Mucous Membranes

If you experience symptoms such as mouth ulcers, redness, difficulty in swallowing or talking, abdominal pain, and painful bowel movements as a drug side effect, consult your doctor as they may adjust the dose if necessary or prescribe alternative medication.
Practice good hygiene, such as washing your hands regularly, to prevent infection.
Drink plenty of water to keep your mucous membranes hydrated and promote healing.
Avoid spicy or acidic foods, which can irritate the mucous membranes and exacerbate inflammation.
Increase your intake of omega-3 fatty acids, found in fatty fish, nuts, and seeds, to reduce inflammation.
Follow a soft food diet to reduce discomfort and promote healing.

Drug Warnings

ALRUBICIN 100MG INJECTION should be avoided if you are allergic to it. It is contraindicated in patients having a recent history of myocardial infarction (MI) or heart attack, patients with baseline neutrophil count < 1500 cells/mm3, severe arrhythmias, previous treatment with anthracyclines and severe hepatic dysfunction. Hence avoid using this medicine under such conditions. Inform your doctor if you have any cardiovascular conditions, liver/kidney disease, or taking any medicines such as cardiotoxic drugs (e.g., Thalidomide, doxorubicin, Abiraterone, tamoxifen, letrozole), and cimetidine, as it can cause serious adverse effects. ALRUBICIN 100MG INJECTION is known to cause embryo-fetal toxicity. Hence it is contraindicated in pregnant or breastfeeding women. ALRUBICIN 100MG INJECTION is not recommended for children as it is known to cause anthracycline-induced acute manifestations of cardiotoxicity and chronic CHF. Do not stop receiving ALRUBICIN 100MG INJECTION without a doctor’s advice, as it can cause serious health conditions. ALRUBICIN 100MG INJECTION is known to cause severe life-threatening haematological reactions, tissue necrosis, cardiomyopathy, secondary acute myelogenous leukaemia, and severe myelosuppression in some patients. Hence careful monitoring of the patient is needed while receiving the medicine.

Drug-Drug Interactions

EpirubicinZiprasidone

Critical

EpirubicinDisopyramide

Severe

Drug-Drug Interactions

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EpirubicinZiprasidone

Critical

How does the drug interact with Alrubicin 100mg Injection:
Using ziprasidone together with Alrubicin 100mg Injection can increase the risk of an irregular heart rhythm

How to manage the interaction:
Taking Ziprasidone with Alrubicin 100mg Injection is not recommended, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

EpirubicinDisopyramide

Severe

How does the drug interact with Alrubicin 100mg Injection:
The combined use of Efavirenz and Disopyramide can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Efavirenz and Disopyramide can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.

EpirubicinEtanercept

Severe

How does the drug interact with Alrubicin 100mg Injection:
When Etanercept is used with Alrubicin 100mg Injection, the likelihood or severity of infection may increase.

How to manage the interaction:
Co-administration of Etanercept with Alrubicin 100mg Injection can result in an interaction, but it can be taken if a doctor has advised it. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.

EpirubicinInfliximab

Severe

How does the drug interact with Alrubicin 100mg Injection:
Combining Infliximab with Alrubicin 100mg Injection can increase the risk or severity of developing serious infections.

How to manage the interaction:
Taking Infliximab with Alrubicin 100mg Injection together can result in an interaction, but it can be taken if your doctor has advised it. If you have any of these symptoms like fever, chills, diarrhea, sore throat, muscle pain, difficulty breathing, weight loss, and pain or burning when you pee, contact a doctor right away. Do not stop using any medications without a doctor's advice.

EpirubicinMifepristone

Severe

How does the drug interact with Alrubicin 100mg Injection:
Co-administration of Alrubicin 100mg Injection with mifepristone can increase the risk of irregular heart rhythms. Prolonged treatment with Mifepristone may result in low potassium levels.

How to manage the interaction:
Taking Alrubicin 100mg Injection with mifepristone together is avoided as it can result in an interaction, it can be taken if a doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, rapid heartbeat, weakness, tiredness, drowsiness, confusion, painful muscle cramping, nausea, or vomiting, constipation, abdominal cramping, chest pain, and/or swelling in the legs or feet, get medical attention. Do not discontinue any medications without consulting a doctor.

EpirubicinMoxifloxacin

Severe

How does the drug interact with Alrubicin 100mg Injection:
Using Moxifloxacin together with Alrubicin 100mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Moxifloxacin with Alrubicin 100mg Injection together can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heart rhythm, vomiting, dizziness, difficulty breathing, or irregular heartbeat call a doctor right away. Do not discontinue any medications without consulting a doctor.

EpirubicinNilotinib

Severe

How does the drug interact with Alrubicin 100mg Injection:
Coadministration of Alrubicin 100mg Injection and nilotinib can increase the risk of an irregular heart rhythm. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Alrubicin 100mg Injection and nilotinib together can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without consulting your doctor.

EpirubicinChloroquine

Severe

How does the drug interact with Alrubicin 100mg Injection:
Using chloroquine together with Alrubicin 100mg Injection can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a interaction between Chloroquine and Alrubicin 100mg Injection, but it can be taken together if prescribed by a doctor. However, consult your doctor if you experience sudden dizziness, lightheadedness, fainting, shortness of breath. Do not discontinue any medications without consulting a doctor.

EpirubicinGatifloxacin

Severe

How does the drug interact with Alrubicin 100mg Injection:
Taking Alrubicin 100mg Injection with Gatifloxacin can increase the risk or severity of irregular heart rhythms. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Taking Alrubicin 100mg Injection with Gatifloxacin together can result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.

EpirubicinHydroxychloroquine

Severe

How does the drug interact with Alrubicin 100mg Injection:
The combined use of Alrubicin 100mg Injection and Hydroxychloroquine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Alrubicin 100mg Injection and Hydroxychloroquine can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Try to eat more healthy fats, fruits, vegetables and whole-grain foods to give you more energy.
Stay hydrated by drinking plenty of water, as dehydration is often seen in cancers.
Taking a stroll in the garden or spending 30 minutes of your time doing some light physical activity can be very useful. However, do not over-exert yourself if you feel too tired.
Avoid smoking and alcohol consumption.
Doing meditation and yoga for some time is very effective in helping cancer patients maintain a healthy attitude and body.

Side Effects of ALRUBICIN 100MG INJECTION

Nausea
Abdominal pain
Vomiting
Dizziness
Back pain
Pain at the site of injection
Red discoloration of urine
Loss of appetite
Mouth sores
Tiredness
Weight gain
Pale skin

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

ALRUBICIN 100MG INJECTION Substitute

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Author Details

Written By

Lakshmithulasi Yarragunta

Pharm-D (PB)

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does ALRUBICIN 100MG INJECTION work?

ALRUBICIN 100MG INJECTION contains Epirubicin, which belongs to the class of anthracycline topoisomerase inhibitors. It inhibits the topoisomerase II enzyme by intercalating the DNA base pairs. This causes double helix DNA to be uncoiled, thereby destroying the DNA and RNA synthesis.

Can ALRUBICIN 100MG INJECTION affect my ability to get pregnant?

ALRUBICIN 100MG INJECTION can disrupt a woman's natural menstrual cycle (period) and inhibit sperm production in men. However, you should not presume that you cannot become pregnant or that you cannot make someone else pregnant. It may also harm your foetus. Use reliable methods of birth control while on treatment with ALRUBICIN 100MG INJECTION.

Drug-Drug Interactions Checker List

THALIDOMIDE
DOXORUBICIN
ABIRATERONE
TAMOXIFEN
LETROZOLE
PACLITAXEL
DOCETAXEL
CIMETIDINE
CILNIDIPINE
NIFEDIPINE

Special Advise

Avoid having intercourse while on treatment with ALRUBICIN 100MG INJECTION.
Regular monitoring of complete blood count (CBC) and liver function (LFT) is important while receiving ALRUBICIN 100MG INJECTION.

Disease/Condition Glossary

Breast Cancer: Breast cancer is a type of cancer with abnormal growth in the cells of the breast. There are different kinds of breast cancer, such as cancer occurring in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), and in the fatty tissue or the fibrous connective tissue within the breast. Symptoms of breast cancer include a lump in the breast, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, a lump or swelling under the arm, unexplained change in shape, size or appearance of the breast, peeling, flaking or scaling of the skin.