Alzumab 25mg Injection

Alzumab 25mg Injection belongs to the class of 'immunomodulators', primarily used to treat psoriasis. Psoriasis is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. Alzumab 25mg Injection may also be used to treat autoimmune conditions like rheumatoid arthritis and multiple sclerosis. Alzumab 25mg Injection is currently being used and trialled to treat cytokine storm (excessive immune response) in COVID-19 (Corona Virus Disease-19) patients. 

Alzumab 25mg Injection consists of 'Itolizumab' that is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody (that serve as a substitute antibody). It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Alzumab 25mg Injection is also being used in COVID-19 infection to reduce the severity of inflammation and damage in the lungs. It is thought to decrease the cytokine storm, an excessive immune response in the lungs of a COVID-19 infected person.

Your doctor will decide the dose and duration based on the medical condition. Common side effects of Alzumab 25mg Injection include pain and swelling at the injection site, upper respiratory tract infection, fever, itching, dizziness, and diarrhoea. These side effects are not familiar to everyone and vary individually. However, if the side effects are persistent, please reach out to your doctor.

Before starting Alzumab 25mg Injection, inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, weak immune system (HIV), tuberculosis, hepatitis B, and active infections. Let your doctor know if you are pregnant or breastfeeding before starting Alzumab 25mg Injection. Alzumab 25mg Injection may cause dizziness, so drive only if you are alert and focused. Alzumab 25mg Injection should not be given to children and adolescents under 18 years of age as safety has not been established. Avoid consuming alcohol along with Alzumab 25mg Injection as it could lead to increased dizziness. 

Alzumab 25mg Injection treats inflammation in patients with psoriasis and rheumatoid arthritis. It contains 'Itolizumab,' which is a humanized recombinant IgG1 (Immunoglobulin G1) monoclonal antibody. It works by reducing the synthesis of cytokine, a substance released by the body that initiates an inflammatory response. Lately, Alzumab 25mg Injection is also being used in COVID-19 infection to reduce breathing complications, the severity of inflammation, and damage in the lungs. It is being used to decrease the cytokine storm, an excessive immune response that occurs in the lungs of a COVID-19-infected person. 

Inform your doctor if you have any liver, heart or kidney diseases, bone marrow suppression, low blood cell count, weak immune system (HIV), neutropenia (low levels of neutrophils), lymphopenia (low levels of lymphocytes), tuberculosis, hepatitis B, C, and active infections before starting Alzumab 25mg Injection. Avoid close contact with people who have infections like chickenpox, measles, tuberculosis, and flu that can be easily spread. Thoroughly wash your hands to prevent the spread of infection. Do not take live vaccines while being treated with Alzumab 25mg Injection to prevent any serious consequences. Alzumab 25mg Injection may cause dizziness, so drive only if you are alert and focused. Avoid consuming alcohol along with Alzumab 25mg Injection as it could lead to increased dizziness. Alzumab 25mg Injection is not recommended in children and adolescents younger than 18 years of age as safety and efficacy is not established. Store Alzumab 25mg Injection at temperatures of 2°C to 8°C. Do not freeze the vial.

• Maintain proper weight by following a healthy and well-balanced diet.
• Avoid smoking and alcohol consumption.
• Try to avoid stress by practising meditation or yoga.
• Try including selenium-rich food sources like Brazil nuts, yellowfin tuna, rice, beans, whole-wheat bread, dairy products, ham, chicken, turkey, beef, eggs, pork, baked beans, mushrooms, oatmeal, and spinach.
• Include zinc-rich sources like meat, shellfish, legumes, hemp seeds, nuts, eggs, dairy products, whole grains, potatoes, kale, and dark chocolate in your diet.
• Cut down on sugar, salt and processed foods.
• Drink plenty of water.

• Pain and swelling at the injection site
• Upper respiratory tract infection
• Fever
• Itching
• Dizziness
• Diarrhoea 

• It is advised to closely monitor the patient for infections like active tuberculosis during and after the treatment though the patient gets a negative tuberculin test.
• It is essential to inform your doctor if you have any active viral, bacterial, and fungal infections before starting Alzumab 25mg Injection.

Psoriasis: It is a skin disorder in which skin cells multiply and form bumpy (uneven) red patches covered with white scales. These red patches can commonly appear on the scalp, elbows, knees, and lower back. Psoriasis is a noncontagious (not spread by contact), chronic immune condition with no cure. It can be mild, moderate, and severe based on the patches coverage on the skin.

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. 

COVID-19: It is a disease caused by SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2). It mainly affects the respiratory system and is spread through droplets generated when an infected person coughs, sneezes, or exhales. Common symptoms include fever, dry cough, tiredness, body aches, sore throat, loss of taste and smell, and conjunctivitis. With the severity of the disease, symptoms like dropping oxygen saturation levels, shortness of breath, chest pain, high fever, and severe weakness are also noticed. The coronavirus can further lead to complications like pneumonia, respiratory failure, heart problems, liver problems, septic shock, and death.