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Prescription drugWhats That
324 people bought in last 7 days
Composition
GLIMEPIRIDE-2MG
Manufacturer/Marketer
Sanofi India Ltd
Consume Type
ORAL
Return Policy
Not Returnable
Expires on or after
Apr-24
for this medicine
Drug-Drug Interactions
GlimepirideSibutramine
Severe
GlimepirideThioridazine
Severe
Drug-Drug Interactions
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GlimepirideSibutramine
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Taking Amaryl 2 mg Tablet with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Amaryl 2 mg Tablet with Sibutramine may lose the weight and may leads to hypoglycemia sometimes.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with sibutramine if prescribed by the doctor. The doctor may advise frequent monitoring of a blood sugar and adjustment of your diabetic regimen both during and after treatment with sibutramine. Let the doctor know if you experience symptoms of low blood glucose such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideThioridazine
Severe
How does the drug interact with Amaryl 2 mg Tablet:
When Amaryl 2 mg Tablet is taken with Thioridazine may interfere with blood glucose control and reduce the effectiveness of Amaryl 2 mg Tablet.
How to manage the interaction:
Taking Amaryl 2 mg Tablet with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
When Amaryl 2 mg Tablet is taken with Thioridazine may interfere with blood glucose control and reduce the effectiveness of Amaryl 2 mg Tablet.
How to manage the interaction:
Taking Amaryl 2 mg Tablet with Thioridazine together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these signs - really high or low blood sugar levels - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
GlimepirideNorfloxacin
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Co-administration of Norfloxacin with Amaryl 2 mg Tablet may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
Co-administration of Norfloxacin with Amaryl 2 mg Tablet may sometimes affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with norfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms such as nervousness, confusion, headache, dizziness, drowsiness, tremors, nausea, hunger, weakness, perspiration, palpitation, rapid heartbeat, increased urination, increased thirst, and increased hunger. Maintaining blood glucose levels is advised. Do not discontinue any medications without consulting a doctor.
GlimepirideVilazodone
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Taking Amaryl 2 mg Tablet with Vilazodone may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Vilazodone if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Taking Amaryl 2 mg Tablet with Vilazodone may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Vilazodone if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideVoriconazole
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Co-administration of Amaryl 2 mg Tablet with Voriconazole may increase the blood levels and effects of Amaryl 2 mg Tablet.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with voriconazole if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
Co-administration of Amaryl 2 mg Tablet with Voriconazole may increase the blood levels and effects of Amaryl 2 mg Tablet.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with voriconazole if prescribed by the doctor. Consult the prescriber if you experience headache, dizziness, and rapid heartbeat. Do not discontinue the medications without consulting a doctor.
GlimepirideIndometacin
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Taking indomethacin with Amaryl 2 mg Tablet may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with indomethacin if prescribed by the doctor. Consult the doctor if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat.
Taking indomethacin with Amaryl 2 mg Tablet may increase the risk of low blood sugar.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with indomethacin if prescribed by the doctor. Consult the doctor if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat.
GlimepirideKetoprofen
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Taking Ketoprofen with Amaryl 2 mg Tablet may increase the risk of hypoglycemia (low blood sugar).
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Ketoprofen if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not taking the medications without consulting a doctor.
Taking Ketoprofen with Amaryl 2 mg Tablet may increase the risk of hypoglycemia (low blood sugar).
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Ketoprofen if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. Do not taking the medications without consulting a doctor.
GlimepirideSparfloxacin
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Co-administration of Sparfloxacin with Amaryl 2 mg Tablet can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Sparfloxacin with Amaryl 2 mg Tablet can affect blood glucose levels. Both high blood glucose and, less frequently, low blood glucose have been reported.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Sparfloxacin if prescribed by the doctor. Consult the prescriber if you experience symptoms of low blood sugar such as headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat (or) symptoms of high blood sugar like increased thirst, increased hunger, and increased urination. Monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideLeflunomide
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Co-administration of Leflunomide may increase the blood levels and effects of Amaryl 2 mg Tablet.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
Co-administration of Leflunomide may increase the blood levels and effects of Amaryl 2 mg Tablet.
How to manage the interaction:
Although there is a possible interaction, Amaryl 2 mg Tablet can be taken with Leflunomide if prescribed by the doctor. Consult the doctor if your condition changes or you experience increased side effects. Regular monitoring of blood glucose levels is advised. Do not discontinue the medications without consulting a doctor.
GlimepirideGrepafloxacin
Severe
How does the drug interact with Amaryl 2 mg Tablet:
Co-administration of Amaryl 2 mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Although there is a possible interaction between Amaryl 2 mg Tablet and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Co-administration of Amaryl 2 mg Tablet with Grepafloxacin can sometimes affect blood glucose levels. Both hyperglycemia (high blood glucose) and, less frequently, hypoglycemia (low blood glucose) have been reported.
How to manage the interaction:
Although there is a possible interaction between Amaryl 2 mg Tablet and Grepafloxacin, you can take these medicines together if prescribed by a doctor. If you experience any of these symptoms - low blood sugar, headache, dizziness, sleepiness, confusion, shaking, feeling hungry, weak, heart racing, high blood sugar, low blood sugar, serious infections, bleeding, feeling anxious, feeling sick or very thirsty - make sure to call a doctor right away. Do not stop using any medications without talking to a doctor.
Drug-Food Interactions
No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.
Drug-Food Interactions
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Drug-Diseases Interactions
GLIMEPIRIDE-2MGHypertensive heart and renal disease
Severe
GLIMEPIRIDE-2MGUnspecified kidney failure
Severe
Drug-Diseases Interactions
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GLIMEPIRIDE-2MGHypertensive heart and renal disease
Severe
How does the disease interact with Amaryl 2 mg Tablet:
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
When compared to diet alone or diet plus insulin, the use of oral hypoglycemic medications may be associated with an increased risk of cardiovascular mortality. This alert is based on the University Group Diabetes Programme (UGDP) project, a long-term prospective clinical investigation aimed to assess the efficacy of glucose-lowering medications in preventing or delaying vascular problems in non-insulin-dependent diabetes patients. Patients treated for 5 to 8 years with diet with a fixed dose of either tolbutamide (a sulfonylurea) or phenformin (a biguanide) had a cardiovascular death risk nearly 2.5 times that of patients treated with diet alone, resulting in the cessation of both therapies in the research. Regardless of how these findings are interpreted, doctors and patients should be aware of the possibility.
How to manage the interaction:
The use of oral hypoglycemic agents may be associated with an increased risk of heart problems. Let the doctor know if you have heart problems.
GLIMEPIRIDE-2MGUnspecified kidney failure
Severe
How does the disease interact with Amaryl 2 mg Tablet:
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
Sulfonylureas are metabolised in the liver and eliminated in the urine and faeces as metabolites (some of which have pharmacologic activity). Patients with poor liver and/or renal function who are treated with sulfonylureas may be exposed to increased serum drug concentrations, increasing the risk of severe hypoglycemia episodes. In the context of hepatic impairment, gluconeogenic ability may be reduced, adding to the risk. Sulfonylurea therapy should be used with caution in people who have liver or kidney illness. It is possible that lower dosages and longer intervals between dosage adjustments will be required. If hypoglycemia occurs during treatment, it may be prolonged in these patients due to slower medication metabolism and/or excretion.
How to manage the interaction:
In patients with kidney problems, severe hypoglycemic episodes may occur. Therapy should be administered cautiously in patients with renal disease.
GLIMEPIRIDE-2MGOther disorders of adrenal gland
Moderate
How does the disease interact with Amaryl 2 mg Tablet:
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
Hypoglycemia is a common side effect of insulin and/or oral hypoglycemic medications. Patients who are debilitated or malnourished, those with defective counterregulatory mechanisms (e.g., autonomic neuropathy and adrenal or pituitary insufficiency), and those receiving beta-adrenergic blocking agents should exercise caution when using these drugs.
How to manage the interaction:
Care should be taken in patients who may be particularly susceptible to the development of hypoglycemic episodes during treatment.
GLIMEPIRIDE-2MGAnaemia due to enzyme disorders
Moderate
How does the disease interact with Amaryl 2 mg Tablet:
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
In patients with glucose 6-phosphate dehydrogenase (G6PD) impairment, sulfonylureas can cause hemolytic anaemia. In individuals with G6PD deficiency, these medicines should be administered with caution, and a non-sulfonylurea option should be considered. Postmarketing reports of hemolytic anaemia in patients receiving these medications who did not have known G6PD deficiency have been received.
How to manage the interaction:
Therapy should be used with caution in patients with glucose 6-phosphate dehydrogenase (G6PD) deficiency. The use of a non-sulfonylurea alternative should be considered.
GLIMEPIRIDE-2MGOther disorders of fluid, electrolyte and acid-base balance
Moderate
How does the disease interact with Amaryl 2 mg Tablet:
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
Treatment with sulfonylureas may cause hyponatremia in individuals who are taking other drugs or have medical disorders that cause hyponatremia, or it may stimulate the secretion of antidiuretic hormone. Certain sulfonylureas have been linked to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion, and these medications may enhance the peripheral (antidiuretic) action of ADH and/or increase ADH release. Caution should be exercised when treating individuals who have hyponatremia or are at increased risk of developing hyponatremia, such as the elderly, those using diuretics, or those who are volume-depleted.
How to manage the interaction:
Caution should be used when treating patients with low sodium or at greater risk of developing low sodium such as elderly patients, patients taking diuretics or those who are volume-depleted.
