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  3. Amphogen Emulsion 10 ml

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Amphogen Emulsion 10 ml, Pack of 1 EMULSION
Amphogen Emulsion 10 ml, Pack of 1 EMULSION
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rxMedicinePrescription drug

Composition :

AMPHOTERICIN B-5MG

Manufacturer/Marketer :

Galengen Lifesciences Pvt Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Amphogen Emulsion

Amphogen Emulsion belongs to a class of medication called 'antifungal' used to treat severe fungal infections like leishmaniasis. A fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. 

Amphogen Emulsion contains Amphotericin B, which kills fungi by destroying the fungal outer cell membrane. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents.

Amphogen Emulsion is given by a doctor or nurse. In some cases, you may experience fever, chills, irregular heartbeat, high or low blood pressure, breathing problems, nausea, vomiting, headache, shaking, muscle cramps or pain. Most of these side effects of Amphogen Emulsion do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Amphogen Emulsion or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Amphogen Emulsion. Amphogen Emulsion is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphogen Emulsion as it may affect your ability to drive. If you experience severe adverse effects such as chest pain or difficulty in breathing, or encephalopathy (a brain disease which may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help.

Uses of Amphogen Emulsion

Severe fungal infections

Directions for Use

Amphogen Emulsion will be administered by a healthcare professional; do not self-administer.

Medicinal Benefits

Amphogen Emulsion contains Amphotericin B, an antifungal used to treat severe fungal infections. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Amphogen Emulsion damages fungal cell membranes and kills fungi. Amphogen Emulsion is used to treat infections such as blood infection with candida, cryptococcus, fusarium, zygomycetes, aspergillus, coccidiodes or blastomycetes, or cryptococcal meningitis (inflammation of the brain).

Storage

Keep Amphogen Emulsion out of the sight and reach of children.
Side effects of Amphogen Emulsion 10 ml
  • Talk to your doctor about oral potassium supplements.
  • Eat potassium rich foods such as bananas, avocados, oranges, dark leafy greens, beans and peas, fish, spinach, milk and tomatoes.
  • Rest well; get enough sleep.
  • Wear comfortable layers of clothes and get to a warm place.
  • Drink warm fluids like coffee, tea or hot chocolate.
  • Warm up using a blanket or heating pad.
Here are the seven steps to manage medication-triggered Dyspnea (Difficulty Breathing or Shortness of Breath):
  • Tell your doctor immediately if you experience shortness of breath after taking medication.
  • Your doctor may adjust the medication regimen or dosage or give alternative medical procedures to minimize the symptoms of shortness of breath.
  • Monitor your oxygen levels and breathing rate regularly to track changes and potential side effects.
  • For controlling stress and anxiety, try relaxation techniques like deep breathing exercises, meditation, or yoga.
  • Make lifestyle changes, such as quitting smoking, exercising regularly, and maintaining a healthy weight.
  • Seek emergency medical attention if you experience severe shortness of breath, chest pain, or difficulty speaking.
  • Follow up regularly with your doctor to monitor progress, adjust treatment plans, and address any concerns or questions.
  • Prefer liquid food like juices and soups when you are not likely to eat.
  • Avoid spicy, fatty and fried foods as they cause stomach upset.
  • Eat small and frequent meals, avoiding large meals at a time.
  • Add healthy foods in your diet like fruits and vegetables.
  • Take starchy food like cereals, bread and potatoes etc.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.

Drug Warnings

If you are allergic to Amphotericin B or any other medicines, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Amphogen Emulsion. Amphogen Emulsion is not recommended for children below one month as the safety and effectiveness were not established. Avoid driving after taking Amphogen Emulsion as it may affect your ability to drive. If you experience severe adverse effects such as chest pain, difficulty breathing, or encephalopathy (a brain disease that may cause you to behave strangely, be confused or feel drowsy), seek immediate medical help. If you have diabetes, electrolyte imbalance (low magnesium or potassium levels in the blood), kidney, liver or heart problems, inform your doctor before taking Amphogen Emulsion.

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
Amphotericin bMetrizamide
Severe

Drug-Drug Interactions

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Amphotericin bStreptozocin
Critical
How does the drug interact with Amphogen Emulsion 10 ml:
Taking Amphogen Emulsion 10 ml and streptozocin together can enhance kidney injury and can cause damage to the ear.

How to manage the interaction:
Taking Streptozocin with Amphogen Emulsion 10 ml is not recommended as it can result in an interaction, it can be taken if a doctor has advised it.
Amphotericin bMetrizamide
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Coadministration of Amphogen Emulsion 10 ml and Metrizamide may increase the risk of kidney damage.

How to manage the interaction:
Co-administration of Amphogen Emulsion 10 ml with Metrizamide can result in an interaction, but it can be taken if a doctor has advised it. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, let the doctor know. Do not stop using any medications without talking to a doctor.
Amphotericin bArsenic trioxide
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Using arsenic trioxide together with Amphogen Emulsion 10 ml cholesteryl sulfate can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Co-administration of Amphogen Emulsion 10 ml with Arsenic trioxide can result in an interaction, but it can be taken if a doctor has advised it. If you experience irregular heartbeat, feeling suddenly dizzy or lightheaded, fainting, a fast or strong heartbeat, feeling weak or tired, feeling sleepy or confused, muscle pain, or feeling sick to your stomach. Do not stop using any medications without talking to a doctor.
Amphotericin bPimozide
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Pimozide used with Amphogen Emulsion 10 ml may raise the chance of a significantly abnormal heart rhythm, although it is a rare side effect.

How to manage the interaction:
Although taking Amphogen Emulsion 10 ml and Pimozide together can cause an interaction, it can be taken if a doctor has suggested it. However, if you experience sudden dizziness, lightheadedness, fainting, breathing difficulty, or rapid heartbeat, weakness, tiredness, drowsiness, confusion, muscle pain, cramps, dizziness, nausea, or vomiting, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
Amphotericin bAmiodarone
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Coadministration of amiodarone together with Amphogen Emulsion 10 ml may raise the risk of an abnormal heart rhythm.

How to manage the interaction:
Even though Amiodarone and Amphogen Emulsion 10 ml interact, they can be used if prescribed by a doctor. If you have heart issues or electrolyte imbalances, you may be at greater risk. If you experience unexpected dizziness, lightheadedness, fainting, shortness of breath, weakness, tiredness, drowsiness, confusion, muscle pain, dizziness, nausea, or vomiting, or heart palpitations, get medical attention. Do not discontinue any medications without consulting a doctor.
Amphotericin bIodixanol
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Coadministration of Amphogen Emulsion 10 ml and Iodixanol can cause higher levels of Iodixanol in the blood by reducing its excretion rate.

How to manage the interaction:
There may be a possibility of interaction between Amphogen Emulsion 10 ml and Iodixanol, but it can be taken if prescribed by a doctor. It's important to keep an eye on how much you pee. If you notice any changes, like peeing more or less than usual, it's a good idea to let the doctor know right away. These changes could be a sign of different health issues, like problems with your kidneys, diabetes, or dehydration. Other symptoms to watch out for include feeling sick, throwing up, not wanting to eat, gaining or losing weight suddenly, or having trouble breathing. Do not stop using any medications without talking to a doctor.
Amphotericin bIoversol
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Coadministration of Amphogen Emulsion 10 ml and Ioversol may increase the risk of kidney damage.

How to manage the interaction:
There may be a possibility of interaction between Amphogen Emulsion 10 ml and Ioversol, but it can be taken if prescribed by a doctor. If you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. Do not stop using any medications without talking to a doctor.
Amphotericin bDroperidol
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Using droperidol together with Amphogen Emulsion 10 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although taking Amphogen Emulsion 10 ml and Droperidol together can cause an interaction, it can be taken if a doctor has suggested it. If you notice any of these symptoms - an irregular heart rhythm, a heart condition, a condition called congenital long qt syndrome, problems with your heart's conduction, severe or long-lasting diarrhea, vomiting, complications, sudden dizziness, feeling lightheaded, fainting, difficulty breathing, heart palpitations, feeling weak, feeling sleepy, feeling confused, muscle pain, feeling nauseous or vomiting - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Amphotericin bIomeprol
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Coadministration of Amphogen Emulsion 10 ml and Iomeprol may increase the risk of kidney problems.

How to manage the interaction:
Co-administration of Amphogen Emulsion 10 ml with Iomeprol can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you experience any changes, like peeing more or less than usual, nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not stop using any medications without talking to a doctor.
Amphotericin bIopamidol
Severe
How does the drug interact with Amphogen Emulsion 10 ml:
Coadministration of Amphogen Emulsion 10 ml and Iopamidol may increase the risk of kidney problem.

How to manage the interaction:
Taking Amphogen Emulsion 10 ml with Iopamidol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on how much you pee. If you notice any changes like nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm let the doctor know right away. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Wash your hands regularly and keep your hands clean to prevent the spread of germs.
  • Avoid dusty activities and digging in the soil.
  • Wear shoes, a long-sleeved t-shirt and long pants while doing outdoor activities such as yard work, gardening or visiting wooded areas to protect from fungus commonly present in the environment.
  • Maintain a diet that is low in sugar, refined carbohydrates, mould-containing foods and yeast.

Side Effects of Amphogen Emulsion

  • Fever
  • Chills
  • Irregular heartbeat
  • High or low blood pressure
  • Breathing problems
  • Nausea
  • Vomiting
  • Headache
  • Shaking
  • Muscle cramps or pain

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:35 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Amphogen Emulsion contains Amphotericin B, an antifungal that works by damaging fungal cell membranes, thereby killing fungi.

You are not recommended to take Amphogen Emulsion with furosemide as co-administration of these medicines may increase the risk of hypokalaemia (low potassium levels in the blood), and in severe cases, it may lead to paralysis, muscle weakness, irregular heart rhythm, difficulty in breathing or swallowing. However, please consult your doctor before taking Amphogen Emulsion with other medicines.

Amphogen Emulsion may cause blue lips and skin, probably during infusion or in the initial 2 days of treatment. However, your doctor or nurse may arrange certain simple treatments to control such adverse effects.

Yes, a test dose of Amphogen Emulsion may be given in smaller amounts before starting the treatment to check if you are sensitive to any of the ingredients.

You are recommended to use Amphogen Emulsion for as long as your doctor has prescribed it. However, the usual treatment is for a minimum of 14 days. Please consult a doctor if you experience any difficulty while taking Amphogen Emulsion.

Amphogen Emulsion is not used to treat viral infections. Amphogen Emulsion is an antifungal that kills fungi and is used to treat severe fungal infections.

Drug-Drug Interactions Checker List

  • ZIDOVUDINE
  • CICLOSPORIN
  • FLUCYTOSINE
  • FUROSEMIDE
  • METHOTREXATE

Special Advise

  • Regular blood tests are recommended while taking Amphogen Emulsion to monitor blood, liver or kidney functioning and potassium levels.

Disease/Condition Glossary

Fungal infection is a disease in which fungi attack the tissue and cause infection. Fungi are commonly present in nature but do not cause infections normally. However, if the person has a weak immune system, certain types of fungi may infect them. Cryptococcal meningitis is a fungal infection of tissues covering the spinal cord (meninges) and brain. The symptoms include headache, hallucinations, fever, stiff neck, sensitivity to light, nausea and vomiting. Fungal infections in the lungs may be more serious and life-threatening and often cause symptoms similar to tuberculosis or bacterial pneumonia.

Have a query?

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Alcohol

Caution

The interaction of Amphogen Emulsion with alcohol is unknown. Please consult your doctor if you have any concerns regarding this.

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Pregnancy

Consult your doctor

Amphogen Emulsion is a Category B pregnancy drug and is given to a pregnant woman if the doctor thinks the benefits outweigh the risks. Please consult your doctor if you are pregnant or planning pregnancy.

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Breast Feeding

Consult your doctor

It is unknown whether Amphogen Emulsion is excreted in human milk. If you are breastfeeding, inform your doctor before receiving this injection.

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Driving

Caution

Avoid driving after taking Amphogen Emulsion as it may affect your ability to drive or operate machinery.

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Liver

Consult your doctor

Inform your doctor if you have a history of liver diseases/conditions before receiving Amphogen Emulsion.

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Kidney

Consult your doctor

Inform your doctor if you have a history of kidney diseases/conditions before receiving Amphogen Emulsion.

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Children

Caution

Amphogen Emulsion is not recommended for children below one month as the safety and effectiveness were not established.

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