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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Sunny S , MBBS
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About Ampiclox Capsule

Ampiclox Capsule belongs to the group of medicines called 'antibiotics' used to treat a wide range of bacterial infections. It is a 'broad-spectrum antibiotic' which treats bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections. Bacterial infections are caused due to the multiplication of harmful bacteria inside or on the body. 

Ampiclox Capsule contains two antibiotics, namely: Ampicillin and Cloxacillin. Ampiclox Capsule works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.
 
The dose and duration of Ampiclox Capsule may vary depending upon your condition and the severity of the infection. In some cases, Ampiclox Capsule may cause common side-effects such as diarrhoea, rashes, nausea, and vomiting. Most of these side-effects do not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if you experience these side-effects persistently.
 
Inform your doctor if you have any allergy (against any antibiotic), kidney or liver problems. Do not take Ampiclox Capsule on your own as self-medication may lead to antibiotic resistance in which antibiotics fail to act against specific bacterial infections. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption to prevent unpleasant side-effects. Inform your doctor about your health condition and medications to rule out any unpleasant side-effects/interactions.

Uses of Ampiclox Capsule

Bacterial infections

Directions for Use

Take Ampiclox Capsule 30-60minutes before meals as food may cause reduced absorption. Tablet/capsule: Swallow the tablet/capsule as a whole with water; do not crush or chew it.Oral liquid/syrup/suspension/drops: Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Dry syrup: Check the label for directions before use. Add boiled and cooled water up to the mark on the bottle and shake vigorously. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper; shake the pack well before each use. Reconstituted suspension/syrup should be used within five days of preparation.

Medicinal Benefits

Ampiclox Capsule belongs to the group of antibiotic medicines called penicillins. Ampiclox Capsule is composed of two antibiotics, namely: ampicillin and cloxacillin. It is used to treat bacterial infections of the ear, nose, throat, bones, lungs, and post-operative wound infections. It is a broad-spectrum antibiotic which is effective against both gram-positive and gram-negative bacteria. Ampiclox Capsule works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Ampiclox Capsule

  • Diarrhoea
  • Rash
  • Nausea
  • Vomiting

Drug Warnings

Before starting Ampiclox Capsule , please inform your doctor if you have any allergy to any penicillin antibiotics, kidney/liver problems, infectious mononucleosis (viral infection with sore throat and fever), or leukaemia (blood cancer). Consult your doctor immediately if you experience skin rash or prolonged, significant diarrhoea with abdominal pain. Talk to your doctor before taking Ampiclox Capsule if you had diarrhoea after taking antibiotics or inflammation of the bowel. Consult your doctor if you are pregnant or breastfeeding. Avoid alcohol consumption while taking Ampiclox Capsule to prevent unpleasant side-effects.

Drug-Drug Interactions

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AmoxicillinCholera, live attenuated
Severe
AmoxicillinMethotrexate
Severe

Drug-Drug Interactions

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AmoxicillinCholera, live attenuated
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of Ampiclox Capsule and Cholera, live attenuated may reduce the activity of the vaccine.

How to manage the interaction:
If you are currently being treated with Ampiclox Capsule or have been treated within the last 14 days, talk to your doctor before receiving cholera vaccine, live. Do not discontinue the medication without consulting a doctor.
AmoxicillinMethotrexate
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of methotrexate with Ampiclox Capsule can increase the levels and side effects of methotrexate.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Ampiclox Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as tiredness, dizziness, fainting, unusual bleeding or bruising, chills, fever, sore throat, body pains. Consult a doctor immediately. Do not stop using medications without a doctor's advice.
AmoxicillinDoxycycline
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of Ampiclox Capsule with doxycycline may reduce the therapeutic effect of Ampiclox Capsule.

How to manage the interaction:
Although there is a possible interaction between Ampiclox Capsule and Doxycycline, you can take these medicines together if prescribed by your doctor. Do not stop using any medications without consulting a doctor.
AmoxicillinBCG vaccine
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of BCG vaccine with Ampiclox Capsule may reduce the effect of BCG vaccine.

How to manage the interaction:
If you are about to receive BCG vaccine, inform the doctor that you are taking Ampiclox Capsule. Do not discontinue the medication without consulting a doctor.
AmoxicillinZalcitabine
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of Ampiclox Capsule and Zalcitabine can be decreased when combined with Ampiclox Capsule.

How to manage the interaction:
There may be a possibility of interaction between Zalcitabine and Ampiclox Capsule, but it can be taken if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
DicloxacillinMethotrexate
Severe
How does the drug interact with Ampiclox Capsule:
Co-administration of methotrexate with Ampiclox Capsule can increase the levels and effects of methotrexate. This can increase the risk or severity of serious infections.

How to manage the interaction:
Although there is a possible interaction between methotrexate and Ampiclox Capsule, you can take these medicines together if prescribed by your doctor. However, if you experience any symptoms such as nausea, vomiting, mouth ulcers, paleness, fatigue, dizziness, fainting, unusual bleeding or bruising, fever, chills, sore throat, body aches. Consult a doctor immediately. Do not stop using medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Therefore, you are advised to take foods rich in probiotics such as yoghurt/curd, kefir, sauerkraut, tempeh, kimchi, miso, kombucha, buttermilk, natto and cheese.
  • Eat fibre-rich food like whole grains, beans, lentils, berries, broccoli, peas and bananas.
  • Avoid foods rich in calcium, grapefruit and grapefruit juice as they might hinder the absorption of antibiotics.
  • Avoid consumption of alcohol and usage of tobacco.

Habit Forming

No

Therapeutic Class

ANTIBIOTICS

Ampiclox Capsule Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Ampiclox Capsule works by preventing the formation of bacterial cell covering, which is necessary for their survival. Thereby kills the bacteria and helps in treating and preventing bacterial infections.

Diarrhoea might be a side-effect of Ampiclox Capsule . Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience prolonged diarrhoea with abdominal pain, stop taking Ampiclox Capsule and consult your doctor. Do not take anti-diarrhoeal medicine on your own.

Even if you feel better, it is recommended to complete the course of Ampiclox Capsule as prescribed by the doctor as it is an antibiotic, and stopping it in between may lead to antibiotic resistance.

Pseudomembranous colitis (swelling or inflammation of the large intestine) has been reported with the use of antibiotics. If you experience prolonged or significant diarrhoea with abdominal cramps, stop taking Ampiclox Capsule and consult your doctor immediately.

Ampiclox Capsule may affect certain laboratory test results. Inform the person doing the tests that you are taking Ampiclox Capsule .

Ampiclox Capsule may affect the gut flora leading to decreased oestrogen reabsorption and lowered efficacy of combined oral contraceptives. Use other methods of contraception while on treatment with Ampiclox Capsule . Consult your doctor if you have any concerns.

Drug-Drug Interactions Checker List

  • ASPIRIN
  • ALLOPURINOL

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect the body. It can target any body part and multiply very quickly. Symptoms of bacterial infection include chills, fever, headache, nausea, vomiting, diarrhoea, abdominal pain, and loss of appetite. Anyone can become infected with a bacterial infection. But, people with a weak immune system or taking immunosuppressive medicines are more prone to bacterial infection.

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