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  3. Apexitra SB 65 Capsule 10's

Apexitra SB 65 Capsule 10's, Pack of 10 CapsuleS
Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Whats That

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Composition :

ITRACONAZOLE-65MG

Manufacturer/Marketer :

Apex Laboratories Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Apexitra Sb 65 Cap

Apexitra Sb 65 Cap belongs to a class of drugs called antifungals used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. Fungal infection is a disease in which a fungus attacks the tissue and causes infection. Fungal infections may be contagious (spread from one person to another).

Apexitra Sb 65 Cap contains Itraconazole, an antifungal that works by inhibiting the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes that are essential for their survival as they prevent the entry of unwanted substances into the cells and stop the leakage of cell contents. Thus, causes the main components of fungal cells to leak out and kill fungi and clear the fungal infection.

Take Apexitra Sb 65 Cap as prescribed. Your doctor will advise you on how often you take Apexitra Sb 65 Cap based on your medical condition. Some people may experience nausea, headache, diarrhoea, tiredness, cough, cold, throat pain, back pain and stomach pain. Most of these side effects of Apexitra Sb 65 Cap do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are known to be allergic to Apexitra Sb 65 Cap or any other medicines, please tell your doctor. Apexitra Sb 65 Cap is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy or a nursing mother, it is advised to consult a doctor before using Apexitra Sb 65 Cap . Do not take Apexitra Sb 65 Cap if you have or had heart failure as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart or lung problems, inform your doctor before taking Apexitra Sb 65 Cap . Avoid taking fentanyl (a strong opioid narcotic medicine) with Apexitra Sb 65 Cap as it may cause severe breathing problems and can even lead to death. If you experience numbness or tingling in your hands or feet, stop taking Apexitra Sb 65 Cap and consult your doctor immediately as they might be symptoms of nerve damage.

Uses of Apexitra Sb 65 Cap

Fungal infections

Directions for Use

Tablet: Take it with food to avoid stomach upset or as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it. If you are taking any stomach acid suppressor or have achlorhydria (stomach does not produce hydrochloric acid), take Apexitra Sb 65 Cap with cola. Oral suspension: Shake the bottle well before use and take it on an empty stomach at least 1 or 2 hours before meals as prescribed by your doctor with a measuring cup or spoon provided.

Medicinal Benefits

Apexitra Sb 65 Cap is an antifungal used to treat fungal infections of the mouth, throat, toenails, fingernails or lungs. The fungal cell membranes are essential for their survival as they prevent the entry of unwanted substances into the cells and stops the leakage of cell contents. Apexitra Sb 65 Cap inhibits the production of ergosterol (a main component of cell membranes of fungi). Thereby, weakens and damages the fungal cell membranes causing the main components of fungal cells to leak out. Thus, kills fungi and clears the fungal infection.

Storage

Store in a cool and dry place away from sunlight
Side effects of Apexitra SB 65 Capsule
Here are the steps to Dry Mouth (xerostomia) caused by medication:
  • Inform your doctor about dry mouth symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Drink plenty of water throughout the day to help keep your mouth moist and alleviate dry mouth symptoms.
  • Chew sugar-free gum or candies to increase saliva production and keep your mouth moisturized.
  • Use saliva substitutes, such as mouthwashes or sprays, only if your doctor advises them to help moisturize your mouth and alleviate dry mouth symptoms.
  • Avoid consuming smoking, alcohol, spicy or acidic foods, and other irritants that may aggravate dry mouth symptoms.
  • Schedule regular dental check-ups to keep track of your oral health and handle any dry mouth issues as they arise.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Eat potassium-rich foods like avocados, bananas, spinach, and potatoes.
  • Stay hydrated by drinking plenty of water.
  • Exercise regularly and maintain healthy weight.
  • Manage stress.
  • Prioritize 7-9 hours of sleep each night to help your body and mind recharge.
  • Avoid smoking and limit intake of caffeine.
  • Practice stress-reducing activities like meditation, yoga, or deep breathing to help calm your mind and body.
  • Avoid stimulants and illegal drugs.
  • Call your doctor if it worsens.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.

Drug Warnings

If you are known to be allergic to Apexitra Sb 65 Cap or any other medicines, please tell your doctor. Apexitra Sb 65 Cap is a pregnancy category C drug and may cause harm to the unborn baby. However, if you are pregnant, planning for pregnancy, or are a nursing mother, it is advised to consult a doctor before using Apexitra Sb 65 Cap . Avoid taking fentanyl (a strong opioid pain killer narcotic medicine) with Apexitra Sb 65 Cap , as it may cause severe breathing problems and can even lead to death. Do not take Apexitra Sb 65 Cap if you had heart failure as it may cause severe life-threatening adverse effects. If you experience a yellow colour change of your eyes or skin, dark coloured urine, stomach pain, pale stools, loss of appetite, unusual tiredness, vomiting or nausea, stop taking Apexitra Sb 65 Cap and consult a doctor immediately as they might be symptoms of liver failure. If you have kidney, liver, heart, or lung problems, inform your doctor before taking Apexitra Sb 65 Cap .

Drug-Drug Interactions

verifiedApollotooltip
ItraconazoleIsavuconazole
Critical
ItraconazoleTriazolam
Critical

Drug-Drug Interactions

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ItraconazoleIsavuconazole
Critical
How does the drug interact with Apexitra SB 65 Capsule:
The blood levels and effects of Isavuconazole may be significantly enhanced by taking Apexitra SB 65 Capsule along with it.

How to manage the interaction:
Co-administration of Isavuconazole and Apexitra SB 65 Capsule can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ItraconazoleTriazolam
Critical
How does the drug interact with Apexitra SB 65 Capsule:
Co-administration of Triazolam and Apexitra SB 65 Capsule may significantly increase the levels of Triazolam.

How to manage the interaction:
Although combining Triazolam and Apexitra SB 65 Capsule may possibly lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleFelodipine
Critical
How does the drug interact with Apexitra SB 65 Capsule:
The blood levels and effects of felodipine may be considerably increased by taking Apexitra SB 65 Capsule together with felodipine.

How to manage the interaction:
Although there is a possible interaction between felodipine and Apexitra SB 65 Capsule, they can be taken if prescribed by a doctor. Consult a physician if you have an irregular heartbeat, Edema (accumulation of fluid in hands or legs), or abnormally low blood pressure. Without first consulting a doctor, never stop taking medicines.
ItraconazoleRanolazine
Critical
How does the drug interact with Apexitra SB 65 Capsule:
The blood levels and effects of Ranolazine may be greatly increased when it is used with Apexitra SB 65 Capsule.

How to manage the interaction:
Although Ranolazine and Apexitra SB 65 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop any negative symptoms, including fainting, lightheadedness, dizziness, or rapid heartbeat. Without consulting a doctor, never stop taking any medication.
ItraconazoleTicagrelor
Critical
How does the drug interact with Apexitra SB 65 Capsule:
The blood levels and effects of ticagrelor may be greatly increased when combined with Apexitra SB 65 Capsule.

How to manage the interaction:
Apexitra SB 65 Capsule and ticagrelor may interact, however if prescribed by a physician, they can be used together. While receiving therapy, you should consult a doctor if you develop any unusual bleeding or bruising, swelling, vomiting, blood in your urine or stools, headache, dizziness, or weakness. Without consulting a doctor, never stop taking any medication.
ItraconazoleMethylergometrine
Critical
How does the drug interact with Apexitra SB 65 Capsule:
Co-administration of Methylergometrine and Apexitra SB 65 Capsule may increase the blood levels of Methylergometrine.

How to manage the interaction:
Methylergometrine and Apexitra SB 65 Capsule may interact, but if prescribed by a doctor, they can be used together. Do not discontinue any medications without first consulting your doctor.
ItraconazoleColchicine
Critical
How does the drug interact with Apexitra SB 65 Capsule:
Coadministration of colchicine with Apexitra SB 65 Capsule may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Colchicine with Apexitra SB 65 Capsule can be taken if prescribed by a doctor, despite the possibility of an interaction. However, contact a doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop using any medications without first talking to your doctor.
ItraconazoleAlprazolam
Critical
How does the drug interact with Apexitra SB 65 Capsule:
Alprazolam's blood levels may be significantly raised when combined with Apexitra SB 65 Capsule.

How to manage the interaction:
Although combining Alprazolam and Apexitra SB 65 Capsule may lead to an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you get extremely drowsy and your breathing becomes slow. Without consulting a doctor, never stop taking any medication.
ItraconazoleNisoldipine
Critical
How does the drug interact with Apexitra SB 65 Capsule:
The blood levels and effects of nisoldipine may be greatly increased when used with Apexitra SB 65 Capsule.

How to manage the interaction:
Nisoldipine and Apexitra SB 65 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a physician if you have symptoms that include an irregular heartbeat, accumulation of fluid in legs or hands, or abnormally low blood pressure. Without consulting a doctor, never stop taking any medication.
ItraconazoleErgotamine
Critical
How does the drug interact with Apexitra SB 65 Capsule:
The blood levels and effects of ergotamine may be greatly increased when combined with Apexitra SB 65 Capsule.

How to manage the interaction:
Ergotamine and Apexitra SB 65 Capsule may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you experience a severe headache, shortness of breath, blurred vision, confusion, nausea, vomiting, numbness or tingling, muscle pain or weakness, blue or purple discoloration of the fingers or toes, pale or cold skin, or chest pain or tightness. Without first consulting your doctor, never stop taking medicines.

Drug-Food Interactions

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ITRACONAZOLE-65MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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ITRACONAZOLE-65MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming Grapefruit, Grapefruit juice with Apexitra SB 65 Capsule may impair the absorption of Apexitra SB 65 Capsule, resulting in decreased antifungal effects. Avoid consuming Grapefruit and grapefruit juice with Apexitra SB 65 Capsule.

Diet & Lifestyle Advise

  • Regularly change your socks and wash your feet. Avoid shoes that make your feet sweaty and hot.
  • In wet places such as changing rooms and gym showers, don’t walk on barefoot to prevent fungal infections.
  • Do not scratch the affected area of skin as it can spread the infection to other body parts.
  • Avoid sharing towels, combs, bedsheets, shoes or socks with others.
  • Wash your bed sheets and towels regularly.

Habit Forming

No

Therapeutic Class

ANTIFUNGALS

Apexitra Sb 65 Cap Substitute

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Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Sunny S

Reviewed By

Sunny S

MBBS

Last Updated

Jul 8, 2025 | 9:29 AM IST

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

You are not recommended to take Apexitra Sb 65 Cap with simvastatin as co-administration of these two medicines may cause muscle weakness, unexplained muscle pain or tenderness, dark coloured urine, fever or flu symptoms. However, please consult a doctor before using Apexitra Sb 65 Cap with other medicines.

No, Apexitra Sb 65 Cap is not recommended for use during pregnancy as it may cause harm to the fetus. Also, it is advised to use effective contraceptive measures while taking Apexitra Sb 65 Cap and after 2 months of stopping treatment with Apexitra Sb 65 Cap . However, please inform your doctor if you are pregnant, planning for pregnancy or breastfeeding before taking Apexitra Sb 65 Cap .

Apexitra Sb 65 Cap may cause temporary or permanent hearing loss in some people. It is not necessary for everyone taking Apexitra Sb 65 Cap to experience this adverse effect. However, if you notice any changes in hearing, stop taking Apexitra Sb 65 Cap and consult a doctor immediately.

You are advised to take antacids (drugs used to reduce acid in the stomach) such as omeprazole, pantoprazole and esomeprazole at least 1 hour before or 2 hours after taking Apexitra Sb 65 Cap as co-administration of these medicines at the same time may reduce the effectiveness of Apexitra Sb 65 Cap because antacids decrease the absorption and blood levels of Apexitra Sb 65 Cap . However, please consult a doctor before taking other medicines with Apexitra Sb 65 Cap .

Yes, fungal infection is a contagious skin condition which spreads from one person to another through direct skin to skin contact or by contact with contaminated soil or surfaces and infected animals. Therefore, it is recommended to avoid close direct contact until the infection is clear and avoid sharing things with the infected person as it can also spread the infection.

You are not recommended to stop taking Apexitra Sb 65 Cap without consulting your doctor as it may cause recurring infection. Therefore, take Apexitra Sb 65 Cap for as long as your doctor has prescribed it, and if you experience any difficulty while taking Apexitra Sb 65 Cap , please consult your doctor.

Drug-Drug Interactions Checker List

  • ESOMEPRAZOLE
  • OMEPRAZOLE
  • PANTOPRAZOLE
  • FLUTICASONE
  • BUDESONIDE
  • HYDROCODONE
  • WARFARIN
  • SIMVASTATIN
  • TERFENADINE
  • ALPRAZOLAM

Special Advise

  • Regular blood tests are recommended before and while taking Apexitra Sb 65 Cap to monitor liver functioning especially if you have any liver problems.

Disease/Condition Glossary

Fungal infection: It is a skin disease in which a fungus attacks the tissue and cause infection. It may be contagious (spread from one person to another). The symptoms of a fungal infection include blisters, itching, redness, scaling and swelling of the skin. Yeast infection is caused by a type of fungus called candida and commonly occurs in moist and warm areas of the body. It is not contagious. It may cause infections in the mouth (oral thrush), vagina, nails, groin or armpits.

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