Appitral 80 Tablet 10's

₹428

(Inclusive of all Taxes)

₹64.2 Cashback (15%)

Written By ,

Reviewed By Bayyarapu Mahesh Kumar , M Pharmacy

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Non returnable*

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Prescription drug

Whats That

About Appitral 80 Tablet

Appitral 80 Tablet belongs to a class of medications called ‘Progestogens’ used as a symptomatic treatment in patients with breast cancer and endometrial cancer. Breast cancer develops in cells of the breast cells characterized by a lump in the breast, a change in the shape of the nipple or breast, and bloody discharge from the nipples. Endometrial cancer is the cancer of the womb's lining (uterus), characterized by pelvic pain, bleeding between periods, and pain during sex.

Appitral 80 Tablet contains ‘Megestrol’, which belongs to the class of ‘Progestogens’. It works similarly to the female hormone ‘progesterone’. It interferes with the production or action of hormones involved in cancer growth. This effect helps to slow down the progression of cancer and reduce the symptoms associated with cancer.

Appitral 80 Tablet is available in the form of a tablet and oral suspension. You should take this medicine exactly as prescribed by your doctor. The common side-effects of Appitral 80 Tablet are an increase in appetite, weight gain, shortness of breath, hot flushes (reddening of the face and neck), high blood pressure, increased blood sugar levels, rounded face, constipation, and swelling of a vein due to a blood clot. If any of these side effects persist or get worse, inform your doctor immediately.

Do not take Appitral 80 Tablet if allergic to Megestrol or any contents. Before taking Appitral 80 Tablet , inform your doctor if you have severe liver problems, a history of thrombophlebitis (blood clots), stroke, adrenal gland disorder, and diabetes. Appitral 80 Tablet should be used with caution in elderly patients. Appitral 80 Tablet is not recommended for children, pregnant women, and breastfeeding mothers. Do not consume alcohol, as it may increase the risk of side effects. Appitral 80 Tablet may not affect your ability to drive.

Uses of Appitral 80 Tablet

Breast cancer, Endometrial cancer

Directions for Use

Tablets: Swallow the tablet as a whole with a glass of water. Do not crush, chew, or break it. It can be taken with or without food. Oral suspension: Shake the bottle well before each use. Take the prescribed dose of liquid medicine with a marked measuring spoon, oral syringe, or medicine cup, followed by water. Do not use a household spoon to measure the medicine.

Medicinal Benefits

Appitral 80 Tablet contains ‘Megestrol’, which is used in the treatment of breast cancer and endometrial cancer. It acts by interfering with the production of hormones that cause the development of cancer. It helps to reduce the symptoms of cancer effectively. It can also be used to treat loss of appetite in patients with HIV/AIDS.

Storage

Keep Appitral 80 Tablet out of the sight and reach of children.

Drug Warnings

Appitral 80 Tablet increases the risk of blood clots, so it should be used cautiously in patients with a history of thrombophlebitis. Also, if you notice impaired coordination, difficulty speaking, pain in the groin, pain in the arm or leg (especially in the calf of the leg), shortness of breath, general weakness, headache, and dizziness, inform your doctor immediately as it may be a sign of blood clot. Appitral 80 Tablet is not recommended for use in pregnancy. Use a reliable contraceptive method to prevent pregnancy while using this medicine. You may also need to take a pregnancy test before using this medicine. Appitral 80 Tablet contains lactose, so inform your doctor if you have an intolerance to any sugars.

Drug-Drug Interactions

MegestrolThalidomide

Severe

MegestrolDofetilide

Severe

Drug-Drug Interactions

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MegestrolThalidomide

Severe

How does the drug interact with Appitral 80 Tablet:
Taking Thalidomide together with Appitral 80 Tablet may increase the risk of blood clots.

How to manage the interaction:
Although taking thalidomide and Appitral 80 Tablet together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.

MegestrolDofetilide

Severe

How does the drug interact with Appitral 80 Tablet:
Co-administration of Appitral 80 Tablet and Dofetilide can increase the chance of a serious abnormal heart rhythm. If you suffer from any cardiac conditions or electrolyte disturbances, you may be at higher risk.

How to manage the interaction:
Co-administration of Appitral 80 Tablet with Dofetilide can possibly result in an interaction, but it can be taken if a doctor has advised it. If you're having any of these symptoms like dizziness, fainting, lightheadedness, lack of breath, chest discomfort, or palpitations, consult a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

Eat a healthy diet. Avoid fast food, fried food, processed meats, refined carbs, and added sugar.
Drink plenty of fluids and eat fibre-rich food to prevent constipation.
Manage your weight. Shed excess weight by exercising regularly if you are obese or overweight.
Wear loose, layered clothing during the nighttime, especially in warm weather. This prevents hot flushes.
Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, herbs, and spices.
Get optimal sleep; rest well.
Avoid smoking and alcohol consumption.

Side Effects of Appitral 80 Tablet

Increase in appetite
Weight gain
Shortness of breath
Hot flushes (reddening of the face and neck)
High blood pressure
Increased blood sugar levels
Rounded face
Constipation
Swelling of a vein due to a blood clot

Habit Forming

No

Therapeutic Class

PROGESTINS

Appitral 80 Tablet Substitute

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Drug-Diseases Interactions

No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

How does Appitral 80 Tablet work?

Appitral 80 Tablet contains ‘Megestrol’, which works similarly to the female hormone ‘progesterone’. It interferes with the production or action of hormones involved in cancer growth. This effect helps to slow down the progression of cancer and reduce the symptoms associated with cancer.

Does Appitral 80 Tablet cause weight gain?

Appitral 80 Tablet may increase appetite and cause weight gain. You may gain weight, especially in the waist and the upper back. This effect usually decreases after discontinuing the treatment. However, opt for a healthy diet, exercise regularly, and maintain a normal weight while using this medicine.

Does Appitral 80 Tablet affect fertility?

Appitral 80 Tablet may not affect fertility but may disrupt the menstrual cycle (periods). Though this medicine affects periods, you should take reliable contraceptive measures while using Appitral 80 Tablet to prevent pregnancy as it may cause harmful effects to the unborn baby.

Is Appitral 80 Tablet safe for diabetics?

Appitral 80 Tablet may increase blood glucose levels, so inform your doctor that you have diabetes before taking this medicine. If prescribed, you should monitor blood glucose levels regularly during the treatment.

Is Appitral 80 Tablet a contraceptive?

Appitral 80 Tablet is not a contraceptive and doesn't help to prevent pregnancy. It would be best to discuss the possible benefits and risks associated with this medicine with your doctor before using it.

Drug-Drug Interactions Checker List

DOFETILIDE
WARFARIN

Special Advise

If you are undergoing surgery, inform your doctor that you are taking Appitral 80 Tablet as it may interfere with the healing process.
Please do not stop taking Appitral 80 Tablet without discussing it with your doctor.
Your doctor may advise you to monitor blood pressure regularly and take blood tests to evaluate liver and kidney function while using Appitral 80 Tablet .

Disease/Condition Glossary

Breast cancer: It is a type of cancer that develops in breast cells. Breast cancer may form in lobules (glands that produce milk), ducts of the breast (the pathway that brings milk from glands to the nipple), fatty tissue, or the fibrous connective tissue within the breast. Symptoms include a lump in the breast or tissue thickening which feels different than the normal surrounding tissues, breast pain, redness, swelling, nipple discharge other than breast milk, bloody discharge, unexplained change in shape, size, or appearance of the breast, peeling, flaking or scaling of the skin, and a lump or swelling under the arm. The risk factors of breast cancer are increasing age, family history of breast cancer, and obesity.

Endometrial cancer: It is a type of cancer in which the endometrium (lining of the womb or uterus) is affected. It is usually seen in women above the age of 55 years. Symptoms include bleeding between periods, pelvic pain, and pain during sexual intercourse. Endometrial cancer risk factors are increasing age, obesity, never been pregnant, family history of cancer, and diabetes. This condition is not life-threatening when it is diagnosed and treated in the early stages.