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  1. Home
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  3. Apree 125 mg/80 mg Combipack Capsule 3's

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About Apree 125 mg/80 mg Combipack Capsule 3's

Apree 125 mg/80 mg Combipack Capsule 3's belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apree 125 mg/80 mg Combipack Capsule 3's contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking the neurokinin-1 receptor (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Take Apree 125 mg/80 mg Combipack Capsule 3's as prescribed. You are recommended to take Apree 125 mg/80 mg Combipack Capsule 3's for as long as your doctor has advised it. In some cases, Apree 125 mg/80 mg Combipack Capsule 3's may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen. 

Please tell your doctor if you are allergic to Apree 125 mg/80 mg Combipack Capsule 3's or any other medicines. Apree 125 mg/80 mg Combipack Capsule 3's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apree 125 mg/80 mg Combipack Capsule 3's. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

Uses of Apree 125 mg/80 mg Combipack Capsule 3's

Chemotherapy-induced nausea and vomiting

Medicinal Benefits

Apree 125 mg/80 mg Combipack Capsule 3's contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years. 

Directions for Use

Take Apree 125 mg/80 mg Combipack Capsule 3's with or without food as advised by your doctor. Always take Apree 125 mg/80 mg Combipack Capsule 3's together with other medicines. Swallow it as a whole with some liquid; do not crush, break or chew it.

Storage

Keep Apree 125 mg/80 mg Combipack Capsule 3's out of the sight and reach of children.

Side Effects of Apree 125 mg/80 mg Combipack Capsule 3's

  • Headache
  • Constipation
  • Loss of appetite
  • Tiredness
  • Indigestion
  • Hiccups

Drug Warnings

Please tell your doctor if you are allergic to Apree 125 mg/80 mg Combipack Capsule 3's or any other medicines. Apree 125 mg/80 mg Combipack Capsule 3's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apree 125 mg/80 mg Combipack Capsule 3's. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

Drug Interactions

Drug-Drug Interactions: Avoid taking Apree 125 mg/80 mg Combipack Capsule 3's with antipsychotics (pimozide), antiallergic drugs (terfenadine, astemizole), and gastroprokinetic agents (cisapride). Apree 125 mg/80 mg Combipack Capsule 3's may interact with immunosuppressants (tacrolimus, everolimus, cyclosporine, sirolimus), pain killers (fentanyl, alfentanil), the medicine used to treat an irregular heartbeat (quinidine), anticancer medicines (etoposide, vinorelbine, irinotecan, ifosfamide), blood thinners (acenocoumarol, warfarin), antibiotics (clarithromycin, telithromycin, rifampicin), anticonvulsants (phenytoin, carbamazepine), medicines used to produce calmness or help you sleep (triazolam, phenobarbital, midazolam), antifungals (ketoconazole, voriconazole, posaconazole, itraconazole), antidepressant (nefazodone), corticosteroids (dexamethasone, methylprednisolone), anti-anxiety medicines (alprazolam), antidiabetic agent (tolbutamide) and medicines used to treat migraines and HIV infections.

Drug-Food Interactions: Apree 125 mg/80 mg Combipack Capsule 3's may interact with St. John’s Wort (herbal preparation used to treat depression).

Drug-Disease Interactions: If you have liver disease, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • TACROLIMUS
  • EVEROLIMUS
  • CYCLOSPORINE
  • SIROLIMUS
  • FENTANYL
  • ALFENTANIL
  • QUINIDINE
  • ETOPOSIDE
  • IRINOTECAN
  • ifosfamide
  • ACENOCOUMAROL
  • WARFARIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • TRIAZOLAM
  • PHENOBARBITAL
  • MIDAZOLAM
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • ITRACONAZOLE
  • NEFAZODONE
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • ALPRAZOLAM
  • TOLBUTAMIDE

Habit Forming

No

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Disease/Condition Glossary

Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.

Consult Doctor

About Apree 125 mg/80 mg Combipack Capsule 3's

Apree 125 mg/80 mg Combipack Capsule 3's belongs to a class of drugs called anti-emetics. It is used in combination with other medicines to prevent nausea and vomiting caused by chemotherapy (anti-cancer medicines) in adults and adolescents aged 12 years and above. Nausea is a feeling of uneasiness in the stomach that often comes before vomiting. On the other hand, vomiting is the forcible voluntary or involuntary emptying of stomach contents through the mouth.

Apree 125 mg/80 mg Combipack Capsule 3's contains Aprepitant, a neurokinin 1 (NK1) receptor antagonist which works by blocking the neurokinin-1 receptor (causes the feeling of sickness) present in the vomiting centre in the brain. Thus, it helps prevent nausea and vomiting. 

Take Apree 125 mg/80 mg Combipack Capsule 3's as prescribed. You are recommended to take Apree 125 mg/80 mg Combipack Capsule 3's for as long as your doctor has advised it. In some cases, Apree 125 mg/80 mg Combipack Capsule 3's may cause common side effects such as headache, constipation, loss of appetite, tiredness, indigestion, and hiccups. Most of these side effects do not require medical attention and gradually resolve over time. However, consult your doctor immediately if the side effects persist or worsen. 

Please tell your doctor if you are allergic to Apree 125 mg/80 mg Combipack Capsule 3's or any other medicines. Apree 125 mg/80 mg Combipack Capsule 3's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apree 125 mg/80 mg Combipack Capsule 3's. If you are taking other prescription or non-prescription medicines, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

Apree 125 mg/80 mg Combipack Capsule 3's, Pack of 1 Capsule
COD available

Online payment accepted

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Composition :

APREPITANT-205MG

Manufacturer/Marketer :

Oncostar Pharma Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Country of origin

India

Manufacturer/Marketer address

LOWER LEVEL-6, LL-6 HI LIFE, P.M. STREET, SANTACRUZ (WEST) , MUMBAI, Maharashtra, India - 400054
Other Info - APR0181

FAQs

Apree 125 mg/80 mg Combipack Capsule 3's works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years.

You are not recommended to take erythromycin with Apree 125 mg/80 mg Combipack Capsule 3's as it may increase the blood levels and effects of Apree 125 mg/80 mg Combipack Capsule 3's. Contact your doctor if your condition changes or experience side effects such as diarrhoea, constipation, nausea, or loss of appetite. However, please consult your doctor before taking other medicines with Apree 125 mg/80 mg Combipack Capsule 3's.

You are advised not to take hormonal birth control medicines such as birth control pills, implants, skin patches, and certain Intrauterine devices (IUDs) as they may not work properly when taken together with Apree 125 mg/80 mg Combipack Capsule 3's. Therefore, you are recommended to use another or additional non-hormonal form of birth control method during treatment with Apree 125 mg/80 mg Combipack Capsule 3's and for up to 2 months after using Apree 125 mg/80 mg Combipack Capsule 3's.

Disclaimer

While we strive to provide complete, accurate, and expert-reviewed content on our 'Platform', we make no warranties or representations and disclaim all responsibility and liability for the completeness, accuracy, or reliability of the aforementioned content. The content on our platform is for informative purposes only, and may not cover all clinical/non-clinical aspects. Reliance on any information and subsequent action or inaction is solely at the user's risk, and we do not assume any responsibility for the same. The content on the Platform should not be considered or used as a substitute for professional and qualified medical advice. Please consult your doctor for any query pertaining to medicines, tests and/or diseases, as we support, and do not replace the doctor-patient relationship.
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Alcohol

Consult your doctor

The interaction of alcohol with Apree 125 mg/80 mg Combipack Capsule 3's is unknown. If you have any concerns regarding this, please discuss them with your doctor.

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Pregnancy

Consult your doctor

If you are pregnant or planning pregnancy, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's. Your doctor may prescribe this medicine only if clearly needed.

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Breast Feeding

Consult your doctor

It is unknown whether Aprepitant is excreted in breast milk. Hence, if you are a nursing mother, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

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Driving

Caution

Apree 125 mg/80 mg Combipack Capsule 3's may cause dizziness or drowsiness in some people. Hence, do not drive or operate machinery if you feel dizzy or drowsy after taking Apree 125 mg/80 mg Combipack Capsule 3's.

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Liver

Caution

If you have liver disease, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's. Your doctor may monitor your liver condition.

bannner image

Kidney

Consult your doctor

If you have any kidney problems, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

bannner image

Children

Unsafe

Apree 125 mg/80 mg Combipack Capsule 3's is not recommended for children below 12 years of age.

Author Details

Veda MaddalaDoctor badge

Written By

Veda Maddala

M Pharmacy

Dr Aneela SiddabathuniDoctor badge

Reviewed By

Dr Aneela Siddabathuni

MPharma., PhD

Last Updated

Jul 8, 2025 | 9:49 AM IST

Doctor imageWe provide you with authentic, trustworthy and relevant information

Reference

  1. https://www.medicines.org.uk/emc/files/pil.11261.pdf
  2. https://www.hpra.ie/img/uploaded/swedocuments/8c35c967-1b86-4814-8cd0-85846ece0a0a.pdf
  3. https://www.accessdata.fda.gov/drugsatfda_docs/label/2010/021549s017lbl.pdf

Uses of Apree 125 mg/80 mg Combipack Capsule 3's

Chemotherapy-induced nausea and vomiting

Medicinal Benefits

Apree 125 mg/80 mg Combipack Capsule 3's contains Aprepitant, an anti-emetic (a drug used to treat nausea and vomiting) that works by blocking the action of a natural substance in the brain called neurokinin that causes nausea and vomiting. Thus, it is used in combination with other medicines to prevent nausea and vomiting caused by anti-cancer medicines in adults and adolescents from the age of 12 years. 

Side effects of Apree 125 mg/80 mg Combipack Capsule
  • Consume more protein-rich foods and healthy fats like beans, avocados, cheese, nuts and lean meats to minimize appetite.
  • Prefer foods high in fiber to help feel full for a long time.
  • If you have decreased appetite, eat only when you are hungry.
  • Eat several small meals or snacks all day.
  • Try to take only small sips of fluids while eating.
Here are the 7 steps to manage Dizziness caused by medication:
  • Inform your doctor about dizziness symptoms. They may adjust your medication regimen or prescribe additional medications to manage symptoms.
  • Follow your doctor's instructions for taking medication, and take it at the same time every day to minimize dizziness.
  • When standing up, do so slowly and carefully to avoid sudden dizziness.
  • Avoid making sudden movements, such as turning or bending quickly, which can exacerbate dizziness.
  • Drink plenty of water throughout the day to stay hydrated and help alleviate dizziness symptoms.
  • If you're feeling dizzy, sit or lie down and rest until the dizziness passes.
  • Track when dizziness occurs and any factors that may trigger it, and share this information with your doctor to help manage symptoms.
  • If you have excess nerve pain and numbness, soak in Epsom salt and warm water. This can help ease the pain and associated discomfort.
  • Use compression socks and make sure to rest for a while to get relief from pain.
  • Avoid smoking and intake of alcohol or fluids that aggravate the pain.
  • Massage your feet or affected area often to get relief from pain. Take the medication prescribed by your doctor without fail.
Managing Medication-Triggered Flushing (Reddening of the skin): A Step-by-Step Guide:
  • Consult your doctor if you experience skin redness, itching, or irritation after taking medication.
  • Your doctor may adjust your treatment plan by changing your medication or providing guidance on managing your erythema symptoms.
  • Your doctor may recommend or prescribe certain medications to help alleviate symptoms.
  • Apply cool compresses or calamine lotion to the affected skin area to reduce redness and itching.
  • Stay hydrated by drinking plenty of water to help alleviate symptoms and keep your skin hydrated.
  • Monitor your skin condition closely and promptly report any changes, worsening symptoms, or concerns to your healthcare provider.
Here are the steps to manage the medication-triggered Cough:
  • Tell your doctor about the cough symptoms you're experiencing, which may be triggered by your medication.
  • Your doctor may adjust your treatment plan by changing your medication, adding new medications, or providing guidance on managing your cough symptoms.
  • Practice good hygiene, including frequent handwashing, avoiding close contact with others, and avoiding sharing utensils or personal items.
  • Stay hydrated by drinking plenty of fluids, such as water, tea, or soup, to help thin out mucus and soothe your throat.
  • Get plenty of rest and engage in stress-reducing activities to help your body recover. If your cough persists or worsens, consult your doctor for further guidance.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.

Directions for Use

Take Apree 125 mg/80 mg Combipack Capsule 3's with or without food as advised by your doctor. Always take Apree 125 mg/80 mg Combipack Capsule 3's together with other medicines. Swallow it as a whole with some liquid; do not crush, break or chew it.

Storage

Keep Apree 125 mg/80 mg Combipack Capsule 3's out of the sight and reach of children.

Drug Warnings

Please tell your doctor if you are allergic to Apree 125 mg/80 mg Combipack Capsule 3's or any other medicines. Apree 125 mg/80 mg Combipack Capsule 3's is not recommended for children below 12 years of age. If you are pregnant or breastfeeding, please inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's. Avoid driving or operating machinery if you feel dizzy or sleepy after taking Apree 125 mg/80 mg Combipack Capsule 3's. If you are taking any other prescription or non-prescription medicines, inform your doctor before taking Apree 125 mg/80 mg Combipack Capsule 3's.

Therapeutic Class

ANTIEMETICS

Drug-Drug Interactions

verifiedApollotooltip
AprepitantEliglustat
Critical
AprepitantFlibanserin
Critical

Drug-Drug Interactions

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AprepitantEliglustat
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Apree 125 mg/80 mg Combipack Capsule combined with Eliglustat can considerably raise blood levels of Eliglustat. This raises the possibility of cardiac adverse effects such as abnormal heart rhythm, heart block, and cardiac arrest.

How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Eliglustat together is not recommended as it can lead to an interaction; they can be consumed if prescribed by a doctor. Consult a doctor if you have symptoms such as sudden dizziness, lightheadedness, fainting, shortness of breath, weak heart rate, weak pulse, or heart palpitations. Do not discontinue any medications without consulting a doctor.
AprepitantFlibanserin
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Using flibanserin together with Apree 125 mg/80 mg Combipack Capsule can significantly increase the blood levels of flibanserin.

How to manage the interaction:
Taking Flibanserin and Apree 125 mg/80 mg Combipack Capsule together is not recommended as it can lead to an interaction; they can be taken if prescribed by a doctor. Consult a doctor if you develop any symptoms, such as extreme sleepiness or low blood pressure, that cause dizziness, lightheadedness, or fainting. To reduce the chance of these side effects, use Flibanserin at bedtime. Do not discontinue any medications without consulting a doctor.
AprepitantLomitapide
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Lomitapide blood levels can be significantly increased by combining it with Apree 125 mg/80 mg Combipack Capsule.

How to manage the interaction:
Although using Lomitapide and Apree 125 mg/80 mg Combipack Capsule together may cause an interaction, they can be taken if advised by a doctor. Consult a doctor if you have any of the following symptoms: diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, liver problems causing fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, dark colored urine, light-colored stools, and yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AprepitantTerfenadine
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Terfenadine may increase the blood levels of Terfenadine and leads to irregular heartbeat.

How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Terfenadine together is not recommended as it can lead to an interaction. It is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantAstemizole
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Astemizole may increase the blood levels of Astemizole.

How to manage the interaction:
Although taking Apree 125 mg/80 mg Combipack Capsule and Astemizole together is not recommended as it can lead to an interaction, it is safe if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor. Astemizole should not be combined with any other medications without a doctor's advice.
AprepitantCisapride
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administration with Apree 125 mg/80 mg Combipack Capsule and Cisapride may cause irregular heart rhythm.

How to manage the interaction:
Although taking Apree 125 mg/80 mg Combipack Capsule and Cisapride together is not recommended as it can lead to an interaction, it is safe to do so if your doctor has prescribed it. Contact a doctor if you have palpitations, an irregular pulse, sudden dizziness, lightheadedness, fainting, or shortness of breath. Do not stop taking any medications without visiting a doctor.
AprepitantPimozide
Critical
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Using pimozide together with Apree 125 mg/80 mg Combipack Capsule may significantly increase the blood levels of pimozide. High blood levels of pimozide can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Taking Apree 125 mg/80 mg Combipack Capsule and Pimozide together is not recommended; as it can lead to an interaction, you can take them if your doctor advises you to. If you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or a rapid heartbeat, get immediate medical help. Do not discontinue any medications without consulting a doctor.
AprepitantOlaparib
Severe
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Apree 125 mg/80 mg Combipack Capsule may significantly raise olaparib levels in the blood. This has a tendency to intensify side effects.

How to manage the interaction:
Despite the fact that Apree 125 mg/80 mg Combipack Capsule and naloxegol interact, it can be taken if prescribed by a doctor. If you have paleness, tiredness, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or pain while urinating , consult a doctor. Do not discontinue any medications without consulting a doctor.
AprepitantIvabradine
Severe
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Co-administartion of Apree 125 mg/80 mg Combipack Capsule and Ivabradine may significantly increase the blood levels of Ivabradine which can result in excessive slowing of heart rate or other side effects.

How to manage the interaction:
Although there is an interaction between Apree 125 mg/80 mg Combipack Capsule and Ivabradine, it can be taken if prescribed by a doctor. If you have dizziness, tiredness, low blood pressure, heart palpitations, chest pain, or worsening shortness of breath, you should see a doctor. Without consulting a doctor, never stop taking medicines.
AprepitantHalofantrine
Severe
How does the drug interact with Apree 125 mg/80 mg Combipack Capsule:
Apree 125 mg/80 mg Combipack Capsule may increase the blood levels of halofantrine. High blood levels of halofantrine can increase the risk of an irregular heart rhythm that may be serious.

How to manage the interaction:
Although co-administration of Apree 125 mg/80 mg Combipack Capsule and halofantrine can lead to interaction, it can be taken if prescribed by a doctor. If you suffer from additional heart problems or electrolyte imbalances, you can be at increased risk. Consult a doctor if you develop any symptoms like heart palpitations, fainting, dizziness, or lightheadedness. Without consulting a doctor, never stop taking medicines.

Drug-Drug Interactions Checker List

  • PIMOZIDE
  • TERFENADINE
  • ASTEMIZOLE
  • CISAPRIDE
  • TACROLIMUS
  • EVEROLIMUS
  • CYCLOSPORINE
  • SIROLIMUS
  • FENTANYL
  • ALFENTANIL
  • QUINIDINE
  • ETOPOSIDE
  • IRINOTECAN
  • ifosfamide
  • ACENOCOUMAROL
  • WARFARIN
  • CLARITHROMYCIN
  • TELITHROMYCIN
  • RIFAMPICIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • TRIAZOLAM
  • PHENOBARBITAL
  • MIDAZOLAM
  • KETOCONAZOLE
  • VORICONAZOLE
  • POSACONAZOLE
  • ITRACONAZOLE
  • NEFAZODONE
  • DEXAMETHASONE
  • METHYLPREDNISOLONE
  • ALPRAZOLAM
  • TOLBUTAMIDE

Diet & Lifestyle Advise

  • Eat a healthy and low-fat diet that includes lots of fruits and vegetables, lean meats, skinless poultry, nuts, fish, whole grains, and plant-based oils, especially in small portions, as it will be easy for digestion.
  • Avoid eating over-sweet food and include more salty food, especially if you have been vomiting. 
  • Increase the intake of fluids. Drink a small amount of water after small intervals to stay hydrated. 
  • Avoid taking greasy or oily foods, as these foods trigger nausea and vomiting. 
  • If the smell of food makes you feel sick (vomit), do not cook food, as it may worsen your condition. Let someone else do the cooking or use prepared food from the freezer.

Habit Forming

No

Side Effects of Apree 125 mg/80 mg Combipack Capsule 3's

  • Headache
  • Constipation
  • Loss of appetite
  • Tiredness
  • Indigestion
  • Hiccups

Disease/Condition Glossary

Nausea and vomiting: Nausea is an uneasiness in the stomach that usually precedes vomiting. Vomiting, on the other hand, is a normal bodily response in which a person desires to evacuate stomach contents from the mouth aggressively. In brief, nausea and vomiting are symptoms of a variety of disorders, including infections, motion sickness, an early stage of pregnancy, and gastroparesis (slow stomach emptying). Vomiting is controlled by a receptor in the brain known as the chemoreceptor trigger zone (CTZ). After chemotherapy and radiation therapy, nausea and vomiting are common side effects. It can also arise as a side effect of an operation or surgery. Controlling vomiting and nausea in cancer patients is critical for conducting daily tasks. It can cause mental abnormalities, lack of appetite, malnutrition, and dehydration if not managed.

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