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Reviewed By Sunny S , MBBS
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Composition :

IRBESARTAN-300MG

Manufacturer/Marketer :

Sanofi India Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Aprovel 300mg Tablet

Aprovel 300mg Tablet belongs to a group of medicines known as angiotensin II receptor blockers indicated for the treatment of hypertension (high blood pressure) in adults. Additionally, Aprovel 300mg Tablet is used to reduce the risk of heart attack or stroke in adults. Hypertension is a medical condition in which the blood pressure is elevated persistently in the arteries without any known cause. On the other hand, heart attack or stroke occurs due to blocked blood flow to the heart or brain, respectively.

Aprovel 300mg Tablet works by blocking the action of a hormone called angiotensin II in the body that causes the narrowing of blood vessels leading to high blood pressure. Thereby, Aprovel 300mg Tablet widens and relaxes blood vessels. Thus, lowers high blood pressure.

You can take Aprovel 300mg Tablet irrespective of food and swallow it whole with a glass of water. Do not crush, chew, or break it. Your doctor will let you how often you should take your tablets based on your medical condition. In some cases, you may experience nausea, vomiting, fatigue, and orthostatic hypotension. Most of these side effects of Aprovel 300mg Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist, please consult your doctor.

Aprovel 300mg Tablet is not for pregnant women as its use during your pregnancy can cause injury and even death to your unborn baby. It is not known whether Aprovel 300mg Tablet passes into your breast milk or not. Your doctor will decide if you will take Aprovel 300mg Tablet while using Aprovel 300mg Tablet and breastfeeding together. Prolonged intake of Aprovel 300mg Tablet may cause high potassium in the blood (hyperkalemia). Avoid intake of potassium supplements with Aprovel 300mg Tablet as it may lead to high potassium levels in the blood, so the doctor may ask you to have a regular check of your potassium level. Do not consume alcohol with Aprovel 300mg Tablet as it may increase the risk of low blood pressure. Taking Aprovel 300mg Tablet with painkillers (like aspirin and ibuprofen) can increase the risk of kidney problems and reduced the efficiency of Aprovel 300mg Tablet.

Uses of Aprovel 300mg Tablet

Hypertension, Heart failure, Prevents heart attack & heart stroke.

Directions for Use

Swallow Aprovel 300mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Aprovel 300mg Tablet is used to treat high blood pressure and reduce the risk of heart attack or stroke. Aprovel 300mg Tablet is an angiotensin II receptor blocker that decreases high blood pressure by widening and relaxing the blood vessels by blocks the action of a hormone called angiotensin II in the body which causes the narrowing of blood vessels leading to high blood pressure.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Aprovel 300mg Tablet

  • Nausea
  • Vomiting
  • Dizziness
  • Orthostatic hypotension
  • Fatigue

Drug Warnings

Aprovel 300mg Tablet is not recommended for people with impaired kidney function, diabetes or severe liver problems. Aprovel 300mg Tablet may increase the risk of low blood pressure when taken with alcohol. Aprovel 300mg Tablet may cause tiredness or dizziness in some people. Make sure you are not affected before driving. Breastfeeding women are advised to consult a doctor before taking Aprovel 300mg Tablet. Avoid intake of potassium supplements with Aprovel 300mg Tablet as it may lead to high potassium levels in the blood, so the doctor may ask you to have a regular check of your potassium level. Do not consume alcohol with Aprovel 300mg Tablet as it may increase the risk of low blood pressure. Taking Aprovel 300mg Tablet with painkillers (like aspirin and ibuprofen) can increase the risk of kidney problems and reduced efficiency of Aprovel 300mg Tablet.

Drug-Drug Interactions

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IrbesartanSpironolactone
Severe
IrbesartanRamipril
Severe

Drug-Drug Interactions

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IrbesartanSpironolactone
Severe
How does the drug interact with Aprovel 300mg Tablet:
Taking Aprovel 300mg Tablet with Spironolactone may increase potassium levels in the blood, which may lead to side effects.

How to manage the interaction:
Taking Aprovel 300mg Tablet with Spironolactone can result in an interaction, it can be taken if a doctor has advised it. However, consult the doctor if you experience nausea, vomiting, weakness, confusion, tingling in your hands and feet, feeling of heaviness in your legs, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop taking any medication without doctors advise.
IrbesartanRamipril
Severe
How does the drug interact with Aprovel 300mg Tablet:
Taking Ramipril together with Aprovel 300mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Aprovel 300mg Tablet with Ramipril together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanBenazepril
Severe
How does the drug interact with Aprovel 300mg Tablet:
Taking Aprovel 300mg Tablet with Benazepril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Aprovel 300mg Tablet and Benazepril together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanLofexidine
Severe
How does the drug interact with Aprovel 300mg Tablet:
Co-administration of Aprovel 300mg Tablet with Lofexidine can decrease the low blood pressure, which may lead to side effects.

How to manage the interaction:
Taking Aprovel 300mg Tablet with Lofexidine can possibly result in an interaction, but it can be taken if a doctor has advised it. However, if you notice any of these signs - slow heart rate, headache, feeling dizzy or lightheaded, or fainting - make sure to contact a doctor right away. Avoid activities requiring mental focus like driving, operating dangerous equipment. Be careful while getting up from a sitting or lying position. Do not discontinue any medications without consulting a doctor.
IrbesartanPotassium chloride
Severe
How does the drug interact with Aprovel 300mg Tablet:
Taking Aprovel 300mg Tablet with Potassium chloride may increase potassium levels in the blood.

How to manage the interaction:
Although taking Aprovel 300mg Tablet with Potassium chloride together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanNaproxen
Severe
How does the drug interact with Aprovel 300mg Tablet:
Co-administration of Aprovel 300mg Tablet along with naproxen may result in side effects including low blood pressure, impaired kidney function.

How to manage the interaction:
There may be a possible interaction between Naproxen and Aprovel 300mg Tablet, but they can be taken together if they are prescribed by a doctor. However, if you experience any symptoms such as nausea, vomiting, decreased hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, breathing difficulty, muscle pains, dizziness, confusion, and irregular heart rhythm, consult the doctor. Do not discontinue any medication without a doctor's advice.
IrbesartanMoexipril
Severe
How does the drug interact with Aprovel 300mg Tablet:
Taking Aprovel 300mg Tablet with Moexipril may cause low blood pressure, kidney function impairment, and increased potassium levels in the blood.

How to manage the interaction:
Although taking Aprovel 300mg Tablet with Moexipril together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.
IrbesartanEnalapril
Severe
How does the drug interact with Aprovel 300mg Tablet:
Using Enalapril together with Aprovel 300mg Tablet may increase the risk of side effects such as low blood pressure, kidney function impairment, and a condition called hyperkalemia (high blood potassium).

How to manage the interaction:
Although taking Aprovel 300mg Tablet with Enalapril together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, and feelings of heaviness in your legs. Do not stop using any medications without talking to a doctor.
Irbesartanpotassium phosphate
Severe
How does the drug interact with Aprovel 300mg Tablet:
Taking Aprovel 300mg Tablet with Potassium phosphate may increase potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis and heart problems.

How to manage the interaction:
Although taking Aprovel 300mg Tablet with potassium phosphate together can possibly result in an interaction, it can be taken if a doctor has prescribed it. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, slow or irregular heartbeat. It is advised to reduce the intake of foods high in potassium, including tomatoes, raisins, figs, potatoes, lima beans, bananas, plantains, papayas, pears, cantaloupes, mangoes, and salt substitutes that include potassium during this treatment. Do not discontinue any medications without a doctor's advice.
IrbesartanAmiloride
Severe
How does the drug interact with Aprovel 300mg Tablet:
When used with Aprovel 300mg Tablet, Amiloride may raise potassium levels in the blood. High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and heart problems in extreme cases.

How to manage the interaction:
Although taking Amiloride and Aprovel 300mg Tablet together may lead to an interaction it can be taken if prescribed by the doctor. However, consult a doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, or a slow or irregular heartbeat. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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IRBESARTAN-300MGPotassium rich foods
Moderate

Drug-Food Interactions

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IRBESARTAN-300MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Consuming potassium-containing substances during treatment with Aprovel 300mg Tablet can lead to high potassium levels which may result in side effects like weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Avoid potassium-containing salt substitutes and over-the-counter potassium supplements during Aprovel 300mg Tablet therapy.

Diet & Lifestyle Advise

  • Maintain a low salt diet and minimize eating processed foods as they contain more sodium. Try to replace salt with spices or herbs to add flavour to the food.
  • Do regular exercise such as cycling, walking, jogging, dancing or swimming for a minimum of 30 minutes per day.
  • Chronic stress may also cause high blood pressure. Therefore, avoid stress by changing your expectations, the way you react in certain situations and making time for yourself to do activities that you enjoy.
  • Maintain a diet that is rich in fruits, vegetables, whole grains and low-fat dairy products.
  • Avoid smoking and alcohol intake.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Aprovel 300mg Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Aprovel 300mg Tablet may increase potassium levels in the blood (hyperkalemia). Therefore, it is recommended to avoid intake of potassium supplements and foods that are rich in potassium like coconut water, bananas and broccoli.

Only on doctors consultation, a patient can take Aprovel 300mg Tablet with metformin which has been found to have a beneficial effect on kidneys in a diabetic patient with hypertension.

Not recommended in overweight patients as per studies conducted by researchers,Aprovel 300mg Tablet causes weight gain in normal individuals and thus contraindicated in overweight patients.

Take the missed dose as soon as possible. if it has been too late then a patient is advised to jump to the next dose without attempting double dose to make up for the missed dose.

Absolutely safe to be used in patients with stomach ulcers as there has been no harmful interaction between Aprovel 300mg Tablet and peptic ulcers except occasional nausea. Recently it has been found to have a protective role against stomach ulcers yet not approved for stomach diseases yet.

Drug-Drug Interactions Checker List

  • IBUPROFEN
  • ASPIRIN
  • HEPARIN
  • DIGOXIN
  • LISINOPRIL
  • ENALAPRIL
  • RAMIPRIL
  • AMILORIDE HYDROCHORIDE
  • SPIRONOLACTONE
  • TIZANIDINE
  • TRIMETHOPRIM

Special Advise

  • Monitor your blood pressure regularly and if you notice any fluctuations, please consult a doctor.
  • Low salt diet and regular exercise are recommended along with Aprovel 300mg Tablet for effective results.

Disease/Condition Glossary

High Blood Pressure (Hypertension): When the blood pressure rises, there is too much of force develops on the lining of arteries wall that makes the heart work harder to pump blood throughout the body. This results in the damage of the blood vessels. If high blood pressure is left untreated, it can lead to stroke, heart attack, heart failure, kidney failure, and eye problems.

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