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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
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Composition :

ARIPIPRAZOLE-10MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arifine 10 Tablet

Arifine 10 Tablet belongs to a class of drugs called antipsychotics and mood stabilizers primarily used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Arifine 10 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused due to disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Arifine 10 Tablet contains Aripiprazole which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Arifine 10 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet improves mood swings, depression, and other psychotic problems. 

Take Arifine 10 Tablet as prescribed. Your doctor will advise you how often you take Arifine 10 Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 10 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Arifine 10 Tablet or any other medicines, please tell your doctor. Arifine 10 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine 10 Tablet if you are pregnant or breastfeeding and consult a doctor. Arifine 10 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine 10 Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 10 Tablet . 

Uses of Arifine 10 Tablet

Schizophrenia, Mania, Bipolar disorder

Directions for Use

Tablet: Take it with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Arifine 10 Tablet contains Aripiprazole which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Arifine 10 Tablet inhibits the dopamine receptor in our brain thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet improves overall behavior and thoughts and helps in having a better social life and comfortably doing daily activities. Arifine 10 Tablet may be used in combination with other medicines to treat depression. Additionally, Arifine 10 Tablet is also used to reduce unwanted sounds (tics) severity in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements). 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Arifine 10 Tablet

  • Drowsiness
  • Headache
  • Tiredness
  • Akathisia (inability to sit still)
  • Difficulty in sleeping
  • Light-headedness
  • Indigestion
  • Shaking
  • Blurred vision
  • Nausea
  • Vomiting
  • Anxiety
  • Increased saliva production

Drug Warnings

If you are allergic to Arifine 10 Tablet or any other medicines, please tell your doctor. Arifine 10 Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine 10 Tablet if you are pregnant or breastfeeding and consult a doctor. Arifine 10 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine 10 Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Arifine 10 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 10 Tablet .

Drug-Drug Interactions

verifiedApollotooltip
BaclofenHydrocodone
Severe
BaclofenCodeine
Severe

Drug-Drug Interactions

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BaclofenHydrocodone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.
BaclofenCodeine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Codeine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Codeine if prescribed by the doctor. These medications may cause dizziness, drowsiness, shortness of breath, or palpitations, consult a doctor immediately. Do not stop any medication without a doctor's advice.
BaclofenDezocine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Dezocine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Dezocine if prescribed by the doctor. These may cause dizziness, drowsiness, palpitations, or chest discomfort. Do not stop taking the medications without a doctor's advice.
BaclofenOxycodone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet can enhance the sedative effects of Oxycodone on the central nervous system and can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Oxycodone and Arifine 10 Tablet, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without first talking to your doctor.
BaclofenBuprenorphine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Buprenorphine with Arifine 10 Tablet can increase the risk of side effects.

How to manage the interaction:
Co-administration of Buprenorphine alongside Arifine 10 Tablet can result in an interaction. However, it can be taken if a doctor has advised it. If you experience shortness of breath, chest discomfort, dizziness, or palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BaclofenMorphine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Morphine may increase the risk or severity of side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Arifine 10 Tablet with Morphine together can result in an interaction, it can be taken if a doctor has advised it. However, contact a doctor immediately if you notice any sudden dizziness, lightheadedness, severe headache, shortness of breath, chest pain or tightness, or weakness. Do not stop using any medications without consulting a doctor.
BaclofenFentanyl
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of fentanyl and Arifine 10 Tablet can increase sedation and may lead to respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although taking fentanyl and Arifine 10 Tablet together can result in an interaction, they can be taken if prescribed by a doctor. However, if you experience dizziness, drowsiness, difficulty concentrating, and impairment in judgment, contact your doctor immediately. Do not stop using any medications without talking to your doctor.
BaclofenMethadone
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Methadone may cause serious side effects such as central nervous system depression can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Methadone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenPethidine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet can enhance the sedative effects of Meperidine on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Taking Pethidine with Arifine 10 Tablet together can possibly result in an interaction, but it can be taken if a doctor has advised it. However, consult your doctor immediately if you experience symptoms such as dizziness, drowsiness, difficulty concentrating, and impairment in judgment, reaction speed and motor coordination. Your doctor can recommend other options that won't cause any problems when taken together. Do not stop using any medications without talking to a doctor.
BaclofenEsketamine
Severe
How does the drug interact with Arifine 10 Tablet:
Co-administration of Arifine 10 Tablet with Esketamine may increase the risk or severity of adverse effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet can be used with Esketamine if prescribed by the doctor. Consult a doctor if you experience drowsiness, confusion, difficulty concentrating, and impairment in thinking, judgment, and reaction speed. Do not stop any medication without doctor's consultation.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Arifine 10 Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Arifine 10 Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
ARIPIPRAZOLE-10MGOther disorders of kidney and ureter, not elsewhere classified
Severe
ARIPIPRAZOLE-10MGDisorders of autonomic nervous system
Moderate

Drug-Diseases Interactions

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ARIPIPRAZOLE-10MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Arifine 10 Tablet:
The kidney is the main organ used to remove Arifine 10 Tablet. Arifine 10 Tablet side effects may be more likely to occur in patients with poor renal function due to decreased medication clearance. In these patients, Arifine 10 Tablet therapy should be used with caution. It could be required to modify the dosage.

How to manage the interaction:
Therapy with Arifine 10 Tablet should be administered cautiously in such patients. Dosage adjustments may be necessary.
ARIPIPRAZOLE-10MGDisorders of autonomic nervous system
Moderate
How does the disease interact with Arifine 10 Tablet:
Patients with a history of autonomic dysreflexia should be treated with intrathecal Arifine 10 Tablet with caution because the drug's rapid withdrawal or the presence of nociceptive stimuli can cause an episode of dysreflexia.

How to manage the interaction:
Arifine 10 Tablet should be administered cautiously in patients with autonomic dysreflexia.
ARIPIPRAZOLE-10MGMental disorder, not otherwise specified
Moderate
How does the disease interact with Arifine 10 Tablet:
Both during therapy and after an abrupt withdrawal from the drug, Arifine 10 Tablet may cause or aggravate psychotic symptoms. Patients having a history of psychiatric illnesses should be treated with Arifine 10 Tablet with caution.

How to manage the interaction:
Arifine 10 Tablet may precipitate or exacerbate psychotic symptoms, both during therapy and following abrupt withdrawal of the drug. Therapy with Arifine 10 Tablet should be administered cautiously in patients with a history of psychiatric disorders.
ARIPIPRAZOLE-10MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Arifine 10 Tablet:
Arifine 10 Tablet treatment for epilepsy has occasionally been associated with electroencephalographic (EEG) abnormalities and a decline in seizure control. Patients having a history of seizures should receive Arifine 10 Tablet therapy with caution. Throughout treatment, clinical conditions and EEG should be monitored often.

How to manage the interaction:
Arifine 10 Tablet may occasionally cause decrease in seizure control. Therapy with Arifine 10 Tablet should be administered cautiously in patients with a history of seizures.

FAQs

Arifine 10 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Arifine 10 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Arifine 10 Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.

No, you are not recommended to take Arifine 10 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Arifine 10 Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Arifine 10 Tablet with other medicines.

Arifine 10 Tablet may cause weight gain in some patients but it is not necessary for everyone taking Arifine 10 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Arifine 10 Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

Arifine 10 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Arifine 10 Tablet .

Yes, Arifine 10 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Arifine 10 Tablet and inform your doctor if you have diabetes before taking Arifine 10 Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

No, you are not recommended to stop taking Arifine 10 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Arifine 10 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Arifine 10 Tablet , please consult your doctor so that the dose may be gradually reduced.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Arifine 10 Tablet can be at an increased risk of death. 
  • Arifine 10 Tablet is not prescribed and approved for the treatment of dementia-related psychosis. 
  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Arifine 10 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment. 

Depression: It is a mental condition characterized by low mood and a loss of interest in activities. People affected by this condition are often unsocial and try to keep isolated from other social activities. 

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