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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS

About Arifine 10 Tablet 10's

Arifine 10 Tablet 10's belongs to a class of drugs called antipsychotics and mood stabilizers primarily used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Arifine 10 Tablet 10's also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused due to disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Arifine 10 Tablet 10's contains Aripiprazole which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Arifine 10 Tablet 10's improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet 10's improves mood swings, depression, and other psychotic problems. 

Take Arifine 10 Tablet 10's as prescribed. Your doctor will advise you how often you take Arifine 10 Tablet 10's based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine 10 Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Arifine 10 Tablet 10's or any other medicines, please tell your doctor. Arifine 10 Tablet 10's should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine 10 Tablet 10's if you are pregnant or breastfeeding and consult a doctor. Arifine 10 Tablet 10's is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine 10 Tablet 10's, please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 10 Tablet 10's. 

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

3 Days Returnable

Expires on or after

Apr-24

for this medicine

Uses of Arifine 10 Tablet 10's

Schizophrenia, Mania, Bipolar disorder

Medicinal Benefits

Arifine 10 Tablet 10's contains Aripiprazole which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Arifine 10 Tablet 10's inhibits the dopamine receptor in our brain thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Arifine 10 Tablet 10's improves overall behavior and thoughts and helps in having a better social life and comfortably doing daily activities. Arifine 10 Tablet 10's may be used in combination with other medicines to treat depression. Additionally, Arifine 10 Tablet 10's is also used to reduce unwanted sounds (tics) severity in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements). 

Side Effects of Arifine 10 Tablet 10's

  • Drowsiness
  • Headache
  • Tiredness
  • Akathisia (inability to sit still)
  • Difficulty in sleeping
  • Light-headedness
  • Indigestion
  • Shaking
  • Blurred vision
  • Nausea
  • Vomiting
  • Anxiety
  • Increased saliva production

Directions for Use

Tablet: Take it with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Arifine 10 Tablet 10's or any other medicines, please tell your doctor. Arifine 10 Tablet 10's should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine 10 Tablet 10's if you are pregnant or breastfeeding and consult a doctor. Arifine 10 Tablet 10's is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine 10 Tablet 10's, please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Arifine 10 Tablet 10's. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine 10 Tablet 10's.

Therapeutic Class

ANTIPSYCHOTICS

Drug-Drug Interactions

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BaclofenHydrocodone
Severe
BaclofenSodium oxybate
Severe

Drug-Drug Interactions

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BaclofenHydrocodone
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's with Hydrocodone may increase sedation and respiratory distress (fluid collects in the air sacs of the lungs)

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet 10's can be used with Hydrocodone if prescribed by the doctor. Co-administration of these medications may cause dizziness, drowsiness, difficulty in concentrating, and impaired judgment. Do not stop any medication without doctor's consultation.
BaclofenSodium oxybate
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Sodium oxybate with Arifine 10 Tablet 10's may increase side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet 10's can be used with Sodium oxybate if prescribed by the doctor. Consult the prescriber if you experience drowsiness, dizziness, lightheadedness, confusion, depression, low blood pressure, slow or shallow breathing, and impairment in thinking, judgment, and motor coordination.
BaclofenPentazocine
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's can enhance the sedative effects of Pentazocine on the central nervous system which can lead to side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is a possible interaction between Pentazocine and Arifine 10 Tablet 10's, you can take these medicines together if prescribed by a doctor. Do not stop using any medications without talking to a doctor.
BaclofenBuprenorphine
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Buprenorphine with Arifine 10 Tablet 10's can increase the risk of side effects.

How to manage the interaction:
Co-administration of Buprenorphine alongside Arifine 10 Tablet 10's can result in an interaction. However, it can be taken if a doctor has advised it. If you experience shortness of breath, chest discomfort, dizziness, or palpitations consult a doctor immediately. Do not discontinue any medications without consulting a doctor.
BaclofenButorphanol
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's with Butorphanol can increase the risk of developing side effects.

How to manage the interaction:
Although there is a possible interaction between Arifine 10 Tablet 10's and Butorphanol, you can take these medicines together if prescribed by your doctor. If you notice any symptoms like dizziness, shortness of breath, palpitations, or chest discomfort, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
BaclofenTapentadol
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Tapentadol together with Arifine 10 Tablet 10's can increase the risk or severity of side effects like decreased breathing rate, irregular heart rhythms, or problems with movement and memory.

How to manage the interaction:
Taking Arifine 10 Tablet 10's with Tapentadol can result in an interaction, it can be taken if a doctor has advised it. Contact a doctor immediately if you experience signs such as drowsiness, lightheadedness, palpitations, confusion, severe weakness, or difficulty breathing. Do not discontinue any medications without consulting a doctor.
BaclofenHydromorphone
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's with Hydromorphone may increase the central nervous system and can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet 10's can be used with Hydromorphone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines or a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenMethadone
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's with Methadone may cause serious side effects such as central nervous system depression can lead to serious side effects including respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet 10's can be used with Methadone if prescribed by the doctor. Inform the prescriber if you are taking these two medicines, the doctor may prescribe alternate medicines a dose adjustment, or more frequent monitoring to safely use both medications. Do not discontinue any medications without consulting a doctor.
BaclofenDezocine
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's with Dezocine can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction, Arifine 10 Tablet 10's can be used with Dezocine if prescribed by the doctor. These may cause dizziness, drowsiness, palpitations, or chest discomfort. Do not stop taking the medications without a doctor's advice.
BaclofenRemifentanil
Severe
How does the drug interact with Arifine 10 Tablet 10's:
Co-administration of Arifine 10 Tablet 10's can enhance the sedative effects of Remifentanil on the central nervous system which can lead to serious side effects such as respiratory distress (a condition in which fluid builds up in the lungs).

How to manage the interaction:
Co-administration of Arifine 10 Tablet 10's with Remifentanil can possibly result in an interaction, but it can be taken if a doctor has advised it. They can recommend other options that won't cause any problems. If you notice any symptoms like feeling tired, dizzy, or having trouble focusing, make sure to contact a doctor right away. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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ARIPIPRAZOLE-10MGOther disorders of kidney and ureter, not elsewhere classified
Severe
ARIPIPRAZOLE-10MGDisorders of autonomic nervous system
Moderate

Drug-Diseases Interactions

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ARIPIPRAZOLE-10MGOther disorders of kidney and ureter, not elsewhere classified
Severe
How does the disease interact with Arifine 10 Tablet 10's:
The kidney is the main organ used to remove Arifine 10 Tablet 10's. Arifine 10 Tablet 10's side effects may be more likely to occur in patients with poor renal function due to decreased medication clearance. In these patients, Arifine 10 Tablet 10's therapy should be used with caution. It could be required to modify the dosage.

How to manage the interaction:
Therapy with Arifine 10 Tablet 10's should be administered cautiously in such patients. Dosage adjustments may be necessary.
ARIPIPRAZOLE-10MGDisorders of autonomic nervous system
Moderate
How does the disease interact with Arifine 10 Tablet 10's:
Patients with a history of autonomic dysreflexia should be treated with intrathecal Arifine 10 Tablet 10's with caution because the drug's rapid withdrawal or the presence of nociceptive stimuli can cause an episode of dysreflexia.

How to manage the interaction:
Arifine 10 Tablet 10's should be administered cautiously in patients with autonomic dysreflexia.
ARIPIPRAZOLE-10MGMental disorder, not otherwise specified
Moderate
How does the disease interact with Arifine 10 Tablet 10's:
Both during therapy and after an abrupt withdrawal from the drug, Arifine 10 Tablet 10's may cause or aggravate psychotic symptoms. Patients having a history of psychiatric illnesses should be treated with Arifine 10 Tablet 10's with caution.

How to manage the interaction:
Arifine 10 Tablet 10's may precipitate or exacerbate psychotic symptoms, both during therapy and following abrupt withdrawal of the drug. Therapy with Arifine 10 Tablet 10's should be administered cautiously in patients with a history of psychiatric disorders.
ARIPIPRAZOLE-10MGConvulsions, not elsewhere classified
Moderate
How does the disease interact with Arifine 10 Tablet 10's:
Arifine 10 Tablet 10's treatment for epilepsy has occasionally been associated with electroencephalographic (EEG) abnormalities and a decline in seizure control. Patients having a history of seizures should receive Arifine 10 Tablet 10's therapy with caution. Throughout treatment, clinical conditions and EEG should be monitored often.

How to manage the interaction:
Arifine 10 Tablet 10's may occasionally cause decrease in seizure control. Therapy with Arifine 10 Tablet 10's should be administered cautiously in patients with a history of seizures.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Arifine 10 Tablet 10's.
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Arifine 10 Tablet 10's may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Arifine 10 Tablet 10's can be at an increased risk of death. 
  • Arifine 10 Tablet 10's is not prescribed and approved for the treatment of dementia-related psychosis. 
  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Arifine 10 Tablet 10's, so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Author Details

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Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment. 

Depression: It is a mental condition characterized by low mood and a loss of interest in activities. People affected by this condition are often unsocial and try to keep isolated from other social activities. 

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