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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
Non returnable*
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Composition :

ARIPIPRAZOLE-5MG

Manufacturer/Marketer :

Icon Life Sciences

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arifine-5 Tablet

Arifine-5 Tablet belongs to a class of drugs called antipsychotics and mood stabilizers primarily used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Arifine-5 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused due to disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Arifine-5 Tablet contains Aripiprazole which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Arifine-5 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arifine-5 Tablet improves mood swings, depression, and other psychotic problems. 

Take Arifine-5 Tablet as prescribed. Your doctor will advise you how often you take Arifine-5 Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arifine-5 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Arifine-5 Tablet or any other medicines, please tell your doctor. Arifine-5 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine-5 Tablet if you are pregnant or breastfeeding and consult a doctor. Arifine-5 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine-5 Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine-5 Tablet . 

Uses of Arifine-5 Tablet

Schizophrenia, Mania, Bipolar disorder

Directions for Use

Tablet: Take it with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Arifine-5 Tablet contains Aripiprazole which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Arifine-5 Tablet inhibits the dopamine receptor in our brain thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Arifine-5 Tablet improves overall behavior and thoughts and helps in having a better social life and comfortably doing daily activities. Arifine-5 Tablet may be used in combination with other medicines to treat depression. Additionally, Arifine-5 Tablet is also used to reduce unwanted sounds (tics) severity in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements). 

Storage

Store in a cool and dry place away from sunlight
Side effects of Arifine-5 Tablet
  • Eat fiber-rich foods, fruits, and vegetables, and track your food intake to monitor calorie consumption.
  • Limit takeout and restaurant meals, and weigh yourself weekly to stay motivated.
  • Build balanced meals, allow yourself to enjoy treats in moderation, and prioritize sleep and stress management through exercise and relaxation techniques.
Overcome Medication-Induced Nausea: A 9-Step Plan
  • Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
  • Divide your daily food intake into smaller, more frequent meals to reduce nausea.
  • Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
  • Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
  • Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
  • Use ginger (tea, ale, or candies) to help relieve nausea.
  • Get adequate rest and also avoid strenuous activities that can worsen nausea.
  • Talk to your doctor about taking anti-nausea medication if your nausea is severe.
  • Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
To prevent, manage, and treat Constipation caused by medication usage, follow these steps:
  • Preventing Vomiting (Before it Happens)
  • Take medication exactly as prescribed by your doctor. This can help minimize side effects, including vomiting.
  • Having a small meal before taking your medication can help reduce nausea and vomiting.
  • Talk to your doctor about taking anti-nausea medication along with your prescribed medication.
  • Managing Vomiting (If it Happens)
  • Try taking ginger in the form of tea, ale, or candy to help alleviate nausea and vomiting.
  • What to Do if Vomiting Persists
  • Consult your doctor if vomiting continues or worsens, consult the doctor for guidance on adjusting your medication or additional treatment.
Here are the steps to cope with constipation as a side effect of medication:
  • Inform your doctor about your constipation symptoms. They may adjust your medication or advise alternative treatments.
  • Stay hydrated by drinking sufficient of water (at least 8-10 glasses a day) to help soften stool and promote bowel movements.
  • Increase fibre intake by eating foods high in fibre, such as fruits, whole grains, vegetables and legumes, to help bulk up the stool.
  • Establish a bowel routine by trying to go to the bathroom at the same time each day to train your bowels.
  • Engaging in regular exercise, like walking or yoga, can support in bowel movement stimulation.
  • Consult your doctor if constipation persists, and discuss alternative treatments or adjustments to your medication.
  • Restlessness is related to mental health and needs medical attention if it's severe.
  • Regular practice of meditation and yoga can help calm your mind. This can reduce restlessness.
  • Prevent smoking as it can impact your calmness of body and mind.
  • Talk to your friends and family about restlessness, who can provide a solution for why you feel restless.
  • Get sufficient sleep for a minimum of 6-7 hours to reduce restlessness.
  • Stretching and walking are examples of mild exercises that can improve mobility and reduce muscle stiffness.
  • Improving posture, mobility, and muscle coordination through physical therapy can help manage slowness or stiffness.
  • Maintain healthy weight and advance general health depend on eating a balanced diet.
  • Reducing symptoms like tremors or muscle spasms requires adequate sleep and rest.
Here are the steps to manage medication-triggered tremors or involuntary shaking:
  • Notify your doctor immediately if you experience tremors or involuntary shaking after taking medication or adjusting your medication regimen.
  • Your doctor may adjust your medication regimen or recommend alternative techniques like relaxation, meditation, or journaling to alleviate tremor symptoms.
  • Your doctor may direct you to practice stress-reducing techniques, such as deep breathing exercises, yoga, or journaling.
  • Regular physical activity, such as walking or jogging, can help reduce anxiety and alleviate tremor symptoms.
  • Your doctor may recommend lifestyle changes, such as avoiding caffeine, getting enough sleep, and staying hydrated, to help manage tremors.
  • Maintain regular follow-up appointments with your doctor to monitor tremor symptoms and adjust treatment plans as needed.

Drug Warnings

If you are allergic to Arifine-5 Tablet or any other medicines, please tell your doctor. Arifine-5 Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arifine-5 Tablet if you are pregnant or breastfeeding and consult a doctor. Arifine-5 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arifine-5 Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Arifine-5 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arifine-5 Tablet .

Drug-Drug Interactions

verifiedApollotooltip
AripiprazoleMetoclopramide
Critical
AripiprazoleMethadone
Severe

Drug-Drug Interactions

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Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Arifine-5 Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Arifine-5 Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

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FAQs

Arifine-5 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Arifine-5 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Arifine-5 Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.

No, you are not recommended to take Arifine-5 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Arifine-5 Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Arifine-5 Tablet with other medicines.

Arifine-5 Tablet may cause weight gain in some patients but it is not necessary for everyone taking Arifine-5 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Arifine-5 Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

Arifine-5 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Arifine-5 Tablet .

Yes, Arifine-5 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Arifine-5 Tablet and inform your doctor if you have diabetes before taking Arifine-5 Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

No, you are not recommended to stop taking Arifine-5 Tablet without consulting your doctor as it may worsen the condition or cause recurring symptoms. Therefore, take Arifine-5 Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Arifine-5 Tablet , please consult your doctor so that the dose may be gradually reduced.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Arifine-5 Tablet can be at an increased risk of death. 
  • Arifine-5 Tablet is not prescribed and approved for the treatment of dementia-related psychosis. 
  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Arifine-5 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment. 

Depression: It is a mental condition characterized by low mood and a loss of interest in activities. People affected by this condition are often unsocial and try to keep isolated from other social activities. 

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