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Reviewed By Sunny S , MBBS
Non returnable*
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Manufacturer/Marketer

RPG Life Sciences Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Arpimune ME 25 Capsule

Arpimune ME 25 Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Arpimune ME 25 Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Arpimune ME 25 Capsule as prescribed. You are advised to take Arpimune ME 25 Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Arpimune ME 25 Capsule may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Arpimune ME 25 Capsule inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Arpimune ME 25 Capsule if you are pregnant or breastfeeding. Arpimune ME 25 Capsule increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Uses of Arpimune ME 25 Capsule

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches)

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not break or chew the tablet/capsule.Oral solution: Take the prescribed dose by mouth using the measuring cup provided by the pack. Shake the pack well before use.

Medicinal Benefits

Arpimune ME 25 Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Arpimune ME 25 Capsule

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Loss of appetite
  • Diarrhea

Drug Warnings

Do not take Arpimune ME 25 Capsule if you are allergic to any of the components. Let your doctor know before using Arpimune ME 25 Capsule if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Arpimune ME 25 Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Arpimune ME 25 Capsule inform your doctor if you have any type of cancer. Do not take Arpimune ME 25 Capsule if you are pregnant or planning for pregnancy. Arpimune ME 25 Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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CiclosporinBosentan
Critical
CiclosporinSimvastatin
Critical

Drug-Drug Interactions

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CiclosporinBosentan
Critical
How does the drug interact with Arpimune ME 25 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Arpimune ME 25 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinSimvastatin
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Combining Arpimune ME 25 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Arpimune ME 25 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Arpimune ME 25 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Arpimune ME 25 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinPitavastatin
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Coadministration of pitavastatin with Arpimune ME 25 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Arpimune ME 25 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinZalcitabine
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Co-administration of zalcitabine with Arpimune ME 25 Capsule may significantly decrease the effect of zalcitabine.

How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Arpimune ME 25 Capsule, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
CiclosporinRitonavir
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Taking Arpimune ME 25 Capsule with ritonavir may significantly increases the blood levels of Arpimune ME 25 Capsule.

How to manage the interaction:
Taking ritonavir with Arpimune ME 25 Capsule together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience nausea, vomiting, loose stools, abdominal pain, dizziness, weakness, headache, fits, shaking, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination, contact a doctor. Do not stop using any medications without talking to a doctor.
CiclosporinGolimumab
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Using Arpimune ME 25 Capsule together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking golimumab and Arpimune ME 25 Capsule together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinKetoconazole
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Co-administration of ketoconazole with Arpimune ME 25 Capsule may increases the blood levels of Arpimune ME 25 Capsule.

How to manage the interaction:
Although taking ketoconazole and Arpimune ME 25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if your condition worsens or you encounter more adverse effects, such as nausea, vomiting, diarrhea, abdominal discomfort, exhaustion, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, or increased or decreased urine, consult a doctor. Do not discontinue any medication without consulting a doctor.
CiclosporinEverolimus
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Taking everolimus with cyclosporine may significantly increases the blood levels of everolimus.

How to manage the interaction:
Although taking everolimus and Arpimune ME 25 Capsule together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you experience any unusual symptoms contact a doctor immediately. In case you experience any side effects like persistent cough, fever, chills, mouth ulcers, paleness of skin, or unusual bleeding or bruising, or blood in stools or urine, consult a doctor. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element, tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress the immune system, thereby preventing an attack on a newly transplanted organ. 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.

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