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Reviewed By Sunny S , MBBS
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Composition :

CYCLOSPORINE-25MG

Manufacturer/Marketer :

RPG Life Sciences Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Arpimune ME 25 Capsule

Arpimune ME 25 Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Arpimune ME 25 Capsule contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Arpimune ME 25 Capsule as prescribed. You are advised to take Arpimune ME 25 Capsule for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Arpimune ME 25 Capsule may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Arpimune ME 25 Capsule inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Arpimune ME 25 Capsule if you are pregnant or breastfeeding. Arpimune ME 25 Capsule increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

Uses of Arpimune ME 25 Capsule

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches)

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not break or chew the tablet/capsule.Oral solution: Take the prescribed dose by mouth using the measuring cup provided by the pack. Shake the pack well before use.

Medicinal Benefits

Arpimune ME 25 Capsule belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

Storage

Store in a cool and dry place away from sunlight
Side effects of Arpimune ME 25 Capsule
  • Limit intake of full-fat dairy products, red meat and processed foods rich in saturated fats.
  • Avoid foods with label “partially hydrogenated oils”.
  • Eat more vegetables, fruits, oats, whole grains, lentils and beans to increase fiber intake.
  • Include foods rich in monounsaturated fats like nuts, avocados, olive oil, and oily fish.
  • Limit consumption of egg yolks.
  • Exercise for at least 30 minutes 5 days a week.
  • Aim for weight loss and maintain healthy weight.
  • Quit smoking as smoking raises the risk of heart disease associated with cholesterol.
  • Limit alcohol consumption as excessive drinking may raise cholesterol levels.
Managing Medication-Triggered UTIs: A Comprehensive Approach:
  • Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
  • Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
  • Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
  • Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
  • Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
  • Monitor UTI symptoms and report any changes to your doctor.
  • If antibiotics are prescribed, take them as directed and complete the full course.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
Here's a comprehensive approach to managing medication-triggered fever:
  • Inform your doctor immediately if you experience a fever after starting a new medication.
  • Your doctor may adjust your medication regimen or dosage as needed to minimize fever symptoms.
  • Monitor your body temperature to monitor fever progression.
  • Drink plenty of fluids, such as water or electrolyte-rich beverages, to help your body regulate temperature.
  • Get plenty of rest and engage in relaxation techniques, such as deep breathing or meditation, to help manage fever symptoms.
  • Under the guidance of your doctor, consider taking medication, such as acetaminophen or ibuprofen, to help reduce fever.
  • If your fever is extremely high (over 103°F), or if you experience severe symptoms such as confusion, seizures, or difficulty breathing, seek immediate medical attention.
  • Limit processed foods and eat more vegetables and fruits.
  • Exercise at least 30 minutes every day.
  • Maintain a healthy weight.
  • Quit smoking as it can worsen kidney damage.
  • Control your blood pressure and blood glucose.
  • Limit salt intake and alcohol consumption.
  • Increased creatinine levels must be corrected immediately with the help of a doctor.
  • Reduce strenuous activities that can lead to muscle breakdown and production of creatinine.
  • Sleep for 7-8 hours per night to assist your body in repairing and rebuilding tissue.
  • Manage your blood pressure by implementing changes in lifestyle like losing weight, reducing stress and exercising regularly.
  • Avoid smoking and drinking alcohol.
  • Regular cleansing will help get rid of dead skin cells and stop ingrown hairs.
  • Keep your hormones in balance by managing your stress, eating well and exercising regularly.
  • Shaving, waxing, and bleaching are ways to get rid of extra hair.

Drug Warnings

Do not take Arpimune ME 25 Capsule if you are allergic to any of the components. Let your doctor know before using Arpimune ME 25 Capsule if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Arpimune ME 25 Capsule may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Arpimune ME 25 Capsule inform your doctor if you have any type of cancer. Do not take Arpimune ME 25 Capsule if you are pregnant or planning for pregnancy. Arpimune ME 25 Capsule should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
CiclosporinBosentan
Critical

Drug-Drug Interactions

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CiclosporinSimvastatin
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Combining Arpimune ME 25 Capsule and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Arpimune ME 25 Capsule and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBosentan
Critical
How does the drug interact with Arpimune ME 25 Capsule:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Arpimune ME 25 Capsule with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinPitavastatin
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Coadministration of pitavastatin with Arpimune ME 25 Capsule may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Arpimune ME 25 Capsule is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Arpimune ME 25 Capsule with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinBaricitinib
Critical
How does the drug interact with Arpimune ME 25 Capsule:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Arpimune ME 25 Capsule with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinLeflunomide
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Using leflunomide together with Arpimune ME 25 Capsule can increase the risk of side effects

How to manage the interaction:
Co-administration of Arpimune ME 25 Capsule with leflunomide can possibly result in an interaction, but it can be taken if your doctor has advised it. However, if you experience contact a doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, or pain during urination. Do not stop using any medications without talking to a doctor.
CiclosporinTenofovir alafenamide
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Co-administration of tenofovir alafenamide with Arpimune ME 25 Capsule may increase the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction, tenofovir alafenamide can be taken with Arpimune ME 25 Capsule if prescribed by the doctor. However, consult the doctor if you experience side effects such as diarrhea, nausea, vomiting, abdominal pain, dizziness, weakness, headache, shaking, fits, fever, sore throat, unusual bruising or bleeding, and increased or decreased urination. Do not discontinue the medication without a doctor's advice.
CiclosporinZalcitabine
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Co-administration of zalcitabine with Arpimune ME 25 Capsule may significantly decrease the effect of zalcitabine.

How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Arpimune ME 25 Capsule, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
CiclosporinLercanidipine
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Using lercanidipine can make cyclosporine more effective at suppressing the immune system.

How to manage the interaction:
Co-administration of Arpimune ME 25 Capsule with lercanidipine can possibly result in an interaction, but it can be taken if your doctor has advised it. Avoid taking cyclosporine along with other medications that suppress your immune system. It is important to watch out for any signs of infection and contact your doctor immediately if you experience symptoms such as serious infection, anemia, bleeding problems, paleness, fatigue, dizziness, bruising, fever, chills, diarrhea, sore throat, muscle aches, weight loss, or pain during urination. Do not stop using any medications without first talking to your doctor.
CiclosporinSulfamethizole
Severe
How does the drug interact with Arpimune ME 25 Capsule:
Coadministration of sulfamethizole with Arpimune ME 25 Capsule may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between sulfamethizole and Arpimune ME 25 Capsule, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Therapeutic Class

IMMUNOSUPPRESSANTS

Arpimune ME 25 Capsule Substitute

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Arpimune ME 25 Capsule acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.

If you miss a dose of Arpimune ME 25 Capsule, take the missed dose as soon as you remember it. However, if it is almost time for the next dose, skip the missed dose and take the scheduled dose instead.

Diarrhoea might be a side effect of Arpimune ME 25 Capsule. Drink lots of fluids and eat non-spicy food if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience severe diarrhoea, consult your doctor. Do not take anti-diarrheal medicine on your own.

Yes, the use of Arpimune ME 25 Capsule may cause abnormal facial and body hair growth as a common side effect. Please consult your doctor if you have any concerns.

Arpimune ME 25 Capsule is known to suppress the immune system. As a result, it increases the risk of infections and developing cancers, especially of the skin. Therefore, avoid prolonged exposure to sunlight by wearing suitable protective clothing and use sunscreen regularly.

Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element, tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress the immune system, thereby preventing an attack on a newly transplanted organ. 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.

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