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Written By ,
Reviewed By Sunny S , MBBS

About Arpimune-O 50 mg Softgel Capsule 5's

Arpimune-O 50 mg Softgel Capsule 5's belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis conditions and in the treatment of psoriasis. Organ rejection occurs when patient’s immune system recognizes the donor organ as foreign and tries to eliminate it.

Arpimune-O 50 mg Softgel Capsule 5's contains 'cyclosporine' which works by suppressing the body's immune system. Thereby, prevents organ rejection. It helps decrease pain and swelling, thus providing relief from the symptoms of rheumatoid arthritis.

Take Arpimune-O 50 mg Softgel Capsule 5's as prescribed. You are advised to take Arpimune-O 50 mg Softgel Capsule 5's for as long as your doctor has prescribed it for you depending on your medical conditions. In some cases, Arpimune-O 50 mg Softgel Capsule 5's may cause headache, vomiting nausea, high blood pressure, loss of appetite (feeling unwell and upset stomach), and diarrhoea. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

Before taking Arpimune-O 50 mg Softgel Capsule 5's inform your doctor if you have any allergy, kidney disease, uncontrolled high blood pressure, or any type of cancer. Consult your doctor before taking Arpimune-O 50 mg Softgel Capsule 5's if you are pregnant or breastfeeding. Arpimune-O 50 mg Softgel Capsule 5's increases the risk of infections and skin cancer. Therefore, stay cautious and avoid prolonged exposure to sunlight. Inform your doctor about your health condition and medicines you are taking to rule out any unpleasant side effects.

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Non returnable*
COD available

Online payment accepted

Consume Type

ORAL

Return Policy

Not Returnable

for this medicine

Uses of Arpimune-O 50 mg Softgel Capsule 5's

Prevent organ rejection, Rheumatoid arthritis, psoriasis (a skin disease that causes itchy and dry patches)

Medicinal Benefits

Arpimune-O 50 mg Softgel Capsule 5's belongs to the class of medicines called 'immunosuppressant' used to prevent organ rejection after a transplant. Also, it helps to reduce the pain/inflammation in rheumatoid arthritis and is used in the treatment of severe cases of skin diseases such as eczema, psoriasis and atopic dermatitis, nephrotic syndrome (kidney disease), and eye problems such as endogenous uveitis and Behçet's uveitis. Cyclosporine works by suppressing the body's immune system. Thereby, prevents organ rejection. Also, it reduces the function of the cells that cause inflammation, especially in the joint tissues. Thereby, decreasing pain, inflammation, slowing down the joint damage and disease progression over time.

Side Effects of Arpimune-O 50 mg Softgel Capsule 5's

  • Headache
  • Vomiting
  • Nausea
  • High blood pressure
  • Loss of appetite
  • Diarrhea

Directions for Use

Tablet/Capsule: Swallow it as a whole with a glass of water; do not break or chew the tablet/capsule.Oral solution: Take the prescribed dose by mouth using the measuring cup provided by the pack. Shake the pack well before use.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not take Arpimune-O 50 mg Softgel Capsule 5's if you are allergic to any of the components. Let your doctor know before using Arpimune-O 50 mg Softgel Capsule 5's if you have liver or kidney problems, high blood pressure, low levels of magnesium, and high levels of potassium. Arpimune-O 50 mg Softgel Capsule 5's may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Before taking Arpimune-O 50 mg Softgel Capsule 5's inform your doctor if you have any type of cancer. Do not take Arpimune-O 50 mg Softgel Capsule 5's if you are pregnant or planning for pregnancy. Arpimune-O 50 mg Softgel Capsule 5's should not be taken by breastfeeding mothers as it passes into breast milk. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

Therapeutic Class

IMMUNOSUPPRESSANTS

Drug-Drug Interactions

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CiclosporinPitavastatin
Critical
CiclosporinCidofovir
Critical

Drug-Drug Interactions

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CiclosporinPitavastatin
Critical
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Coadministration of pitavastatin with Arpimune-O 50 mg Softgel Capsule 5's may significantly increase the blood levels of pitavastatin which can increase the risk of side effects such as liver problems and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Pitavastatin with Arpimune-O 50 mg Softgel Capsule 5's is not recommended, as it can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience symptoms like unexpected bruising or bleeding, skin rash, itching, tiredness, nausea, vomiting, yellowing of the skin or eyes, unexplained muscular pain, tenderness, or weakness, fever, dark urine, chills, joint pain, or swelling, consult a doctor. Do not discontinue any medications without a doctor's advice.
CiclosporinCidofovir
Critical
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Taking cyclosporine with cidofovir can increase the risk of kidney problems.

How to manage the interaction:
Taking Arpimune-O 50 mg Softgel Capsule 5's with Cidofovir is not recommended, but can be taken be together if prescribed by a doctor. However, if you experience nausea, vomiting, loss of hunger, increased or decreased urination, sudden weight gain or weight loss, swelling, shortness of breath, bone pain, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm, contact the doctor immediately. Do not discontinue any medications without consulting a doctor
CiclosporinBosentan
Critical
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
When Bosentan is taken with Cyclosporine, it may increase the risk of side effects.

How to manage the interaction:
Taking Arpimune-O 50 mg Softgel Capsule 5's with Bosentan is not recommended, but it can be taken if prescribed by the doctor. However, if you experience any symptoms like severe headache, nausea, or an increased heart rate, consult the doctor immediately. Do not stop using any medications without talking to a doctor.
CiclosporinSimvastatin
Critical
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Combining Arpimune-O 50 mg Softgel Capsule 5's and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Arpimune-O 50 mg Softgel Capsule 5's and Simvastatin together is not recommended as it can lead to an interaction, but it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of hunger, weakness, nausea, vomiting, and yellowing of the skin or eyes, contact the doctor immediately. Do not discontinue any medications without consulting your doctor.
CiclosporinBaricitinib
Critical
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Co-administration of Baricitinib with Cyclosporine can increase the risk of infections as well as some cancers.

How to manage the interaction:
Taking Arpimune-O 50 mg Softgel Capsule 5's with Baricitinib is not recommended as it can cause an interaction, but it can be taken together if prescribed by a doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinCeritinib
Severe
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Using ceritinib and Arpimune-O 50 mg Softgel Capsule 5's may increase the blood levels of Arpimune-O 50 mg Softgel Capsule 5's.

How to manage the interaction:
There may be a possibility of interaction between ceritinib and Arpimune-O 50 mg Softgel Capsule 5's, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience any symptoms such as diarrhea or stomach pain, feeling dizzy or tired, having a headache or fits, having a fever or sore throat, or bleeding or bruising. Do not stop using any medications without a doctor's advice.
CiclosporinCisapride
Severe
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Coadministration of cisapride with cyclosporine may significantly increase the blood levels of cisapride which may increase the risk of an irregular heart rhythm.

How to manage the interaction:
There may be a possibility of interaction between cisapride and Arpimune-O 50 mg Softgel Capsule 5's, but it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations. Do not stop using any medications without a doctor's advice.
CiclosporinGolimumab
Severe
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Using Arpimune-O 50 mg Softgel Capsule 5's together with golimumab may increase the risk of serious infections.

How to manage the interaction:
Although taking golimumab and Arpimune-O 50 mg Softgel Capsule 5's together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning sensation when you urinate, consult a doctor. Do not stop using any medications without a doctor's advice.
CiclosporinZalcitabine
Severe
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Co-administration of zalcitabine with Arpimune-O 50 mg Softgel Capsule 5's may significantly decrease the effect of zalcitabine.

How to manage the interaction:
Although there is a possible interaction between Zalcitabine and Arpimune-O 50 mg Softgel Capsule 5's, you can take these medicines together if prescribed by your doctor. Do not discontinue any medications without consulting a doctor.
CiclosporinSulfadiazine
Severe
How does the drug interact with Arpimune-O 50 mg Softgel Capsule 5's:
Coadministration of sulfadiazine with Arpimune-O 50 mg Softgel Capsule 5's may increases the risk of kidney problems.

How to manage the interaction:
Although there is a possible interaction between sulfadiazine and Arpimune-O 50 mg Softgel Capsule 5's, they can be taken together if your doctor has prescribed them. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.

Drug-Food Interactions

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CYCLOSPORINE-50MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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CYCLOSPORINE-50MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Consuming grapefruit and grapefruit juice while taking Arpimune-O 50 mg Softgel Capsule 5's can increase the effects of Arpimune-O 50 mg Softgel Capsule 5's. Avoid consuming grapefruit and grapefruit juice while taking Arpimune-O 50 mg Softgel Capsule 5's.

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • TACROLIMUS
  • AMILORIDE
  • SPIRONOLACTONE
  • ALISKIREN
  • ATORVASTATIN
  • PITAVASTATIN
  • SIMVASTATIN
  • ERYTHROMYCIN
  • AZITHROMYCIN
  • VORICONAZOLE
  • ITRACONAZOLE
  • DILTIAZEM
  • VERAPAMIL
  • DANAZOL
  • ALLOPURINOL
  • COLCHICINE
  • TELAPREVIR

Diet & Lifestyle Advise

  • Eat foods rich in quercetin (a flavonoid) such as apples, cherries, broccoli, spinach, and blueberries.
  • Consuming food rich in probiotics helps in developing the ing immune system against allergies.
  • Limit intake of food that might trigger allergies such as dairy products, soy, eggs, and nuts.
  • Avoid consumption of foods with excess sugar as flare-up inflammation.
  • Include fruits, vegetables, whole grains, healthy fats and fish in your diet.
  • Reducing stress and maintaining a regular sleep pattern would be helpful.
  • Avoid getting in contact with harsh soaps, detergents, and rough fabrics.

Habit Forming

No

Disease/Condition Glossary

Organ transplant rejection: When you get a new organ transplanted to your body, your body recognizes it as a foreign element, tries to attack and reject it because it is not originally part of your body. So, immunosuppressant drugs like cyclosporine are given to such patients to suppress the immune system, thereby preventing an attack on a newly transplanted organ. 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Psoriasis: It is a long-lasting, inflammatory skin illness. It is not infectious but has a tendency to run in families. It causes itchy and red patches on the skin.

Arpimune-O 50 mg Softgel Capsule 5's Substitute

Substitutes safety advice
  • Sandimmun Neoral 50 mg Capsule 5's

    52.02per tablet
  • Psorid 50 Capsule 5's

    52.02per tablet
  • Iminoral 50 Capsule 5's

    by AYUR

    52.02per tablet
  • Panimun Bioral 50 mg Capsule 6's

    51.75per tablet
  • ARPIMUNE ME 50MG TABLET

    38.52per tablet
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