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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
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ORAL

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Not Returnable

Expires on or after

Jan-27

for this medicine

About Arpizol 20 Tablet

Arpizol 20 Tablet belongs to a class of drugs called antipsychotics and mood stabilizers primarily used to treat mood disorders like schizophrenia, irritability linked with autism, and Tourette's syndrome. Besides this, Arpizol 20 Tablet also helps in managing mental depression along with other antidepressant medicines. Schizophrenia affects the ability of a person to feel, think and behave clearly. Tourette's syndrome is a mental disorder characterized by uncontrollable, repetitive movements or unwanted sounds (tics). Psychosis may be caused due to disturbances in chemical messenger activity known as neurotransmitters (like dopamine and serotonin) in the brain.

Arpizol 20 Tablet contains Aripiprazole which stabilizes and blocks the dopamine and serotonin receptors in the brain, preventing its overactivity, thereby controlling the positive symptoms like hallucinations, misbelief, and unfriendly characteristics of schizophrenia. Arpizol 20 Tablet improves the activity of dopamine and serotonin receptors in other areas of the brain. It helps control negative symptoms (like lack of emotion, social isolation, poor attention, and memory loss) of schizophrenia. Thus, Arpizol 20 Tablet improves mood swings, depression, and other psychotic problems. 

Take Arpizol 20 Tablet as prescribed. Your doctor will advise you how often you take Arpizol 20 Tablet based on your medical condition. Some people may experience drowsiness, headache, tiredness, akathisia (inability to sit still), difficulty sleeping, light-headedness, indigestion, shaking, blurred vision, nausea, vomiting, anxiety, and increased saliva production. Most of these side effects of Arpizol 20 Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Arpizol 20 Tablet or any other medicines, please tell your doctor. Arpizol 20 Tablet should be used with caution in elderly patients above 65 years of age. There is an increased risk of adverse reactions such as dizziness, inability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arpizol 20 Tablet if you are pregnant or breastfeeding and consult a doctor. Arpizol 20 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arpizol 20 Tablet , please contact a doctor immediately. If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, a history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arpizol 20 Tablet . 

Uses of Arpizol 20 Tablet

Schizophrenia, Mania, Bipolar disorder

Directions for Use

Tablet: Take it with or without food as advised by the doctor and swallow it as a whole with a glass of water. Do not crush, chew or break it. Oral solution: Shake the bottle well before use and take it as advised by the doctor. Take it with the help of a measuring cup that is provided with the pack.

Medicinal Benefits

Arpizol 20 Tablet contains Aripiprazole which helps treat various psychotic conditions like schizophrenia, mood disorders (such as mania and bipolar disorder), and sometimes depression. Arpizol 20 Tablet inhibits the dopamine receptor in our brain thereby controlling the positive symptoms (like hallucinations, misbelief, and unfriendliness) and negative symptoms (like social isolation, lack of emotion, poor attention, and memory loss) of schizophrenia. Thus, Arpizol 20 Tablet improves overall behavior and thoughts and helps in having a better social life and comfortably doing daily activities. Arpizol 20 Tablet may be used in combination with other medicines to treat depression. Additionally, Arpizol 20 Tablet is also used to reduce unwanted sounds (tics) severity in Tourette's syndrome (a nervous system problem that causes unwanted sounds or sudden movements). 

Storage

Store in a cool and dry place away from sunlight

Side Effects of Arpizol 20 Tablet

  • Drowsiness
  • Headache
  • Tiredness
  • Akathisia (inability to sit still)
  • Difficulty in sleeping
  • Light-headedness
  • Indigestion
  • Shaking
  • Blurred vision
  • Nausea
  • Vomiting
  • Anxiety
  • Increased saliva production

Drug Warnings

If you are allergic to Arpizol 20 Tablet or any other medicines, please tell your doctor. Arpizol 20 Tablet should be used with caution in elderly patients above 65 years of age as there is an increased risk of adverse reactions such as dizziness, changes in the ability to move and balance, orthostatic hypotension (fall in blood pressure when standing up), and drowsiness. Avoid taking Arpizol 20 Tablet if you are pregnant or breastfeeding and consult a doctor. Arpizol 20 Tablet is not recommended for children below 15 years of age. If you have any self-harming thoughts or behavior while taking Arpizol 20 Tablet , please contact a doctor immediately. If you develop impulse control disorders such as excessive eating, spending, addictive gambling, or abnormally high sex drive, inform your doctor so that the dose may be adjusted appropriately, or are advised to stop taking Arpizol 20 Tablet . If you have diabetes, abnormal blood pressure, high cholesterol, fits, involuntary muscle movements especially in the face, attention-deficit hyperactivity disorder (ADHD), blood clots, history of stroke or heart attack, kidney or liver problems, inform your doctor before taking Arpizol 20 Tablet .

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
AripiprazoleCodeine
Severe

Drug-Drug Interactions

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AripiprazoleMetoclopramide
Critical
How does the drug interact with Arpizol 20 Tablet:
Co-administration of Metoclopramide with Arpizol 20 Tablet can increase the risk of side effects.

How to manage the interaction:
Taking Arpizol 20 Tablet with Metoclopramide is generally avoided as it can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AripiprazoleCodeine
Severe
How does the drug interact with Arpizol 20 Tablet:
Using Arpizol 20 Tablet together with Codeine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although taking Arpizol 20 Tablet and Codeine together can cause an interaction, it can be taken if a doctor has suggested it. However, if you notice trouble breathing, feeling too sleepy or dizzy, having trouble focusing, consult a doctor right away. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Do not stop using any medications without talking to a doctor.
AripiprazolePrimidone
Severe
How does the drug interact with Arpizol 20 Tablet:
Coadministration of Arpizol 20 Tablet and primidone may decrease the blood levels of Arpizol 20 Tablet, which may make Arpizol 20 Tablet less effective in treating the condition.

How to manage the interaction:
Although there is an interaction between primidone and Arpizol 20 Tablet, it can be taken if a doctor has advised it. However, if you experience any unusual symptoms, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AripiprazoleMethadone
Severe
How does the drug interact with Arpizol 20 Tablet:
Using Arpizol 20 Tablet together with Methadone can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Arpizol 20 Tablet with Methadone together can possibly result in an interaction, but it can be taken if a doctor has advised it. Do not exceed the doses, frequency, or duration of usage advised by a doctor. Furthermore, because these medications may induce dizziness, sleepiness, trouble focusing, and impairment in judgement, response speed, and motor coordination, you should avoid driving or operating dangerous machinery. Do not stop using any medications without a doctor's advice.
AripiprazoleTetrabenazine
Severe
How does the drug interact with Arpizol 20 Tablet:
Combining Arpizol 20 Tablet with Tetrabenazine can increase the risk of side effects.

How to manage the interaction:
Taking Arpizol 20 Tablet with Tetrabenazine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience muscle spasms or movements that you can't stop or control, such as lip smacking, chewing, puckering, frowning or scowling, tongue thrusting, teeth clenching, jaw twitching, blinking, eye-rolling, shaking or jerking of arms and legs, tremor, jitteriness, restlessness, pacing, and foot tapping, consult the doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleIomeprol
Severe
How does the drug interact with Arpizol 20 Tablet:
Coadministration of Arpizol 20 Tablet and Iohexol may increase the risk of seizure (a sudden, violent, uncontrollable contraction of a group of muscles).

How to manage the interaction:
Although there is a possible interaction between Arpizol 20 Tablet and Iomeprol, you can take these medicines together if prescribed by a doctor. If you have seizures or a head injury, it's important to contact a doctor right away. Do not discontinue any medications without consulting a doctor.
AripiprazolePethidine
Severe
How does the drug interact with Arpizol 20 Tablet:
Using Arpizol 20 Tablet together with Pethidine can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Although there is a possible interaction between Pethidine and Arpizol 20 Tablet, you can take these medicines together if prescribed by a doctor. Consult a doctor if you experience dizziness, drowsiness, difficulty concentrating, impaired judgment, reaction speed, and motor coordination. Do not discontinue any medications without consulting a doctor.
AripiprazoleButorphanol
Severe
How does the drug interact with Arpizol 20 Tablet:
Using Arpizol 20 Tablet together with Butorphanol can cause central nervous system depression (a physiological state that can result in a decreased rate of breathing, decreased heart rate, and loss of consciousness).

How to manage the interaction:
Taking Arpizol 20 Tablet with Butorphanol together can result in an interaction, but it can be taken if a doctor has advised it. It's important to keep an eye on your health and talk to a doctor about any concerns. They can recommend other options that won't cause any problems. If you notice any of these symptoms - trouble breathing, feeling too sleepy or dizzy, having trouble focusing - make sure to call a doctor right away. Do not stop using any medications without a doctor's advice.
AripiprazoleClozapine
Severe
How does the drug interact with Arpizol 20 Tablet:
Combining Arpizol 20 Tablet with Clozapine can increase the risk of heart problmes including low blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Arpizol 20 Tablet and Clozapine, but it can be taken if prescribed by a doctor. However, if you experience dizziness, drowsiness, blurred vision, confusion, dry mouth, stomach pain, constipation, difficulty urinating, heat intolerance, heart palpitation, or irregular heart rhythm, consult the doctor. Be careful while getting up from a lying position. Avoid activities requiring mental alertness like operating dangerous machinery or driving. Do not stop using any medications without talking to a doctor.
AripiprazoleBupropion
Severe
How does the drug interact with Arpizol 20 Tablet:
Taking bupropion with Arpizol 20 Tablet may raise the chance of seizures (fits), which can happen with either medicine. Furthermore, bupropion can raise Arpizol 20 Tablet levels in the blood, which may increase other side effects.

How to manage the interaction:
Co-administration of bupropion along with Arpizol 20 Tablet can lead to an interaction, it can be taken if recommended by a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Limit the intake of caffeine as it may reduce the effectiveness of Arpizol 20 Tablet .
  • Eat plenty of fruits and vegetables. Eat more fish, especially oily fish such as salmon, sardines, trout, mackerel, pilchards and herring.
  • Cut down sugars, salt and saturated fats.
  • Drink adequate water to keep the body hydrated.
  • Do regular exercise and maintain a stable weight as Arpizol 20 Tablet may cause weight gain.
  • Avoid consumption of alcohol as it may increase drowsiness.

Habit Forming

No

Therapeutic Class

ANTIPSYCHOTICS

Arpizol 20 Tablet Substitute

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Arpizol 20 Tablet contains Aripiprazole, an antipsychotic that works by inhibiting the dopamine receptors in the brain and prevents its overactivity. Thereby, helps in controlling the positive symptoms (such as hallucinations, misbelief and unfriendliness) of schizophrenia. Also, Arpizol 20 Tablet improves the activity of dopamine receptors in other areas of the brain and helps in controlling negative symptoms (such as social isolation, lack of emotion, poor attention and memory loss) of schizophrenia. Thereby, Arpizol 20 Tablet improves behaviour, thoughts and helps in having a better social life and enables to comfortably do daily activities.

No, you are not recommended to take Arpizol 20 Tablet with ibuprofen as co-administration of these medicines may increase the risk of fits and increase the levels of Arpizol 20 Tablet in the blood leading to increased adverse effects. However, please consult a doctor before taking Arpizol 20 Tablet with other medicines.

Arpizol 20 Tablet may cause weight gain in some patients but it is not necessary for everyone taking Arpizol 20 Tablet to experience this side effect. However, in order to avoid gaining weight while taking Arpizol 20 Tablet , you are advised to do regular exercise and avoid high-calorie drinks. Instead take non-alcoholic drinks, herbal tea and lemon water.

Arpizol 20 Tablet is not recommended for dementia (loss of memory or other mental abilities) patients, especially in elderly people as it may cause severe adverse effects including stroke. Therefore, it is advised to inform your doctor if you have dementia or a history of stroke before taking Arpizol 20 Tablet .

Yes, Arpizol 20 Tablet may cause high blood sugar levels. Therefore, regular monitoring of blood sugar levels is recommended while taking Arpizol 20 Tablet and inform your doctor if you have diabetes before taking Arpizol 20 Tablet . However, if you experience dry mouth, increased thirst or urination, fruity breath odour, please consult a doctor as these might be signs of high blood sugar.

Drug-Drug Interactions Checker List

  • METOPROLOL
  • OLANZAPINE
  • FLUOXETINE
  • PAROXETINE
  • VENLAFAXINE
  • ITRACONAZOLE
  • KETOCONAZOLE
  • AMIODARONE
  • FLECAINIDE
  • QUINIDINE
  • NEVIRAPINE
  • EFAVIRENZ
  • INDINAVIR
  • RITONAVIR
  • IBUPROFEN
  • RIFAMPICIN
  • RIFABUTIN
  • PHENYTOIN
  • CARBAMAZEPINE
  • PHENOBARBITAL

Special Advise

  • Elderly patients more than 65 years with dementia-related psychosis treated with Arpizol 20 Tablet can be at an increased risk of death. 
  • Arpizol 20 Tablet is not prescribed and approved for the treatment of dementia-related psychosis. 
  • Increased risk of suicidal thinking and behavior changes has been observed in children, adolescents, and young adults taking Arpizol 20 Tablet , so close monitoring for worsening and the emergence of suicidal thoughts and behaviours is required.  

Disease/Condition Glossary

Schizophrenia: It is a mental disorder that affects a person's ability to feel, think and behave clearly. Mania is a mental condition that causes intense excitement, high energy, and delusions (misbeliefs). Mania may occur due to lack of sleep or sleep pattern changes, high levels of stress, and alcohol intake. Seek medical help immediately if you have any self-harming or suicidal thoughts.

Bipolar disorder: It is also called manic depression, associated with extreme mood swings ranging from manic highs to depressive lows. The symptoms of bipolar disorder include mania (high energy and excitability) and depression (loss of interest, hopelessness, low energy). Bipolar disorder involves lifelong treatment. 

Depression: It is a mental condition characterized by low mood and a loss of interest in activities. People affected by this condition are often unsocial and try to keep isolated from other social activities. 

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