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Written By Urvashi Bharti , MBBS
Reviewed By Sureshvarma D , MPharma
Non returnable*
COD available

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Composition :

ATRACURIUM-10MG

Manufacturer/Marketer :

Neon Laboratories Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Artacil Injection Atracurium

Artacil Injection Atracurium belongs to the group of medicines called skeletal muscle relaxants used to reduce and relieve muscle spasms (excessive tension in the muscles) occurring during surgery in intensive care. Muscle spasm is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms.

Artacil Injection Atracurium contains ‘Atracurium’ that works by blocking the action of acetylcholine on skeletal muscles. Thus, stop sending a pain signal to the brain, relieving muscle stiffness or muscle spasm along with pain and surgery. Artacil Injection Atracurium is used during surgery.  It is also used during general anaesthesia to ease tracheal intubation (a tube into the windpipe) and controlled ventilation.

Artacil Injection Atracurium is given by the healthcare professional during surgery.  In some cases, you may experience tachycardia (rapid heartbeat), temporary hypotension (low blood pressure), wheezing, bronchospasm (asthma-like symptoms), skin flushing, and urticaria (nettle rash). Most of these side effects of Artacil Injection Atracurium do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Before receiving Artacil Injection Atracurium inform your doctor if you have had myasthenia gravis or Eaton-Lambert syndrome,  severe electrolyte disorder, asthma-like symptoms (a history of allergy, asthma or bronchospasm), burns and lack of adequate circulatory filling (hypovolaemia), pregnant or breastfeeding mother. Your doctor will prescribe Artacil Injection Atracurium only if the benefits outweigh the risks. Artacil Injection Atracurium is not recommended in neonates (children under the age of one month). Artacil Injection Atracurium is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer or the fridge.

Uses of Artacil Injection Atracurium

Muscle contraction during surgery

Directions for Use

A healthcare professional will administer Artacil Injection Atracurium under carefully controlled conditions. Do not self-administer Artacil Injection Atracurium .

Medicinal Benefits

Artacil Injection Atracurium belongs to the group of medicines called muscle relaxants used to reduce and relieve muscle contraction (excessive tension in the muscles) during surgery, other procedures, and in intensive care. It is also used to calm muscles while on a breathing machine, during general anaesthesia to ease tracheal intubation (a tube into the windpipe), and controlled ventilation. It works by blocking the action of acetylcholine on skeletal muscles. Also, stop sending a pain signal to the brain, relieving muscle stiffness or muscle spasm along with pain and surgery. An experienced doctor must give Artacil Injection Atracurium under carefully controlled conditions. It is used during procedures that require that the patient is fully anaesthetized (unconscious) or heavily sedated.

Storage

Store in a cool and dry place away from sunlight
Side effects of Artacil Injection Atracurium 2.5 ml
Here are the steps to manage the medication-triggered Tachycardia (Fast Heart Rate):
  • Contact your doctor immediately if you're experiencing a fast heart rate, palpitations, or other heart-related symptoms. This is crucial to determine whether the symptoms are related to your medication.
  • Your doctor may need to adjust your medication regimen to alleviate the fast heart rate symptoms. This could involve changing the medication, reducing the dosage, or adding new medications to counteract the side effects.
  • Follow your doctor's advice on monitoring your heart rate and blood pressure. This will help track any changes and ensure your heart rate returns normal.
  • If you experience severe symptoms such as chest pain, dizziness, or shortness of breath, seek immediate medical attention. These symptoms can indicate a more serious condition that requires prompt treatment.
  • Exercising regularly helps lower the risk of heart problems.
  • Maintain a healthy diet, including vegetables and fruits.
  • Rest well; get enough sleep.
  • Manage stress with yoga and meditation.
  • Limit alcohol and smoking.
  • Injection site reaction can include numbness or redness.
  • Get a physical examination, follow your doctor's instructions, if it worsens or gets swollen.
  • Apply cold compress for pain relief.
  • Practice good hygiene and keep the injection site away from heat and pressure.
  • Avoid scratching the affected area.
  • Wear loose clothing to reduce irritation.
  • Keep the affected area moisturized with a gentle moisturiser.
  • To alleviate the reaction, remove the irritant by immediately stopping contact and washing the area with mild soap and cool water.
  • Apply a cool, wet compress to reduce inflammation and itching.
  • Consult a doctor if your skin reaction is severe, widespread, or accompanied by swelling, blistering, or breathing difficulties.
  • Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
  • Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
  • Protect your skin from extreme heat and try to apply wet compresses.
  • Soak in the cool bath, which gives a soothing impact to the affected area.
Here are the few steps for dealing with itching caused by drug use:
  • Report the itching to your doctor immediately; they may need to change your medication or dosage.
  • Use a cool, damp cloth on the itchy area to help soothe and calm the skin, reducing itching and inflammation.
  • Keep your skin hydrated and healthy with gentle, fragrance-free moisturizers.
  • Try not to scratch, as this can worsen the itching and irritate your skin.
  • If your doctor prescribes, you can take oral medications or apply topical creams or ointments to help relieve itching.
  • Track your itching symptoms and follow your doctor's guidance to adjust your treatment plan if needed. If the itching persists, consult your doctor for further advice.
Managing Low Blood Pressure Triggered by Medication: Expert Advice:
  • If you experience low blood pressure symptoms like dizziness, lightheadedness, or fainting while taking medication, seek immediate medical attention.
  • Make lifestyle modifications and adjust your medication regimen under medical guidance to manage low blood pressure.
  • As your doctor advises, regularly check your blood pressure at home. Record your readings to detect any changes and share them with your doctor.
  • Fluid intake plays a vital role in managing blood pressure by maintaining blood volume, regulating blood pressure, and supporting blood vessel function. Drinking enough fluids helps prevent dehydration, maintain electrolyte balance, and regulate fluid balance.
  • Take regular breaks to sit or lie down if you need to stand for long periods.
  • When lying down, elevate your head with extra pillows to help improve blood flow.
  • Avoid heavy exercise or strenuous activities that can worsen low blood pressure.
  • Wear compression socks as your doctor advises to enhance blood flow, reduce oedema, and control blood pressure.
  • If symptoms persist or worsen, or if you have concerns about your condition, seek medical attention for personalized guidance and care.

Drug Warnings

Before you receive Artacil Injection Atracurium , tell your doctor if you have a disease that affects the muscles and nervous control (neuromuscular disease such as myasthenia gravis or Eaton-Lambert syndrome (muscle disorder)), a severe electrolyte disorder, cancer spread widely from a primary source (carcinomatosis), a sensitivity to histamine, asthma-like symptoms (a history of allergy, asthma or bronchospasm), burns, lack of adequate circulatory filling (hypovolaemia). Artacil Injection Atracurium should not be given to pregnant women unless prescribed. If you are pregnant or breastfeeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking Artacil Injection Atracurium . Mothers should stop breastfeeding for 24 hours after receiving Artacil Injection Atracurium . Artacil Injection Atracurium is not recommended in neonates (children under the age of one month) as safety and effectiveness in pediatric patients below the age of 1 month have not been established. Artacil Injection Atracurium some formulations containing benzyl alcohol. In neonates, benzyl alcohol has been associated with an increased incidence of neurological and other complications, sometimes fatal.

Drug-Drug Interactions

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AtracuriumAmikacin
Severe
AtracuriumBotulinum toxin
Severe

Drug-Drug Interactions

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AtracuriumAmikacin
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Co-administration of Amikacin with Artacil Injection Atracurium 2.5 ml can increase the risk of developing breathing difficulties.

How to manage the interaction:
Taking Artacil Injection Atracurium 2.5 ml with Amikacin together can result in an interaction, but it can be taken if your doctor has advised it. Consult your doctor if you experience shortness of breath, palpitations, chest discomfort, or dizziness. Do not discontinue any medications without consulting a doctor.
AtracuriumBotulinum toxin
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Coadministration of Botulinum toxin with Artacil Injection Atracurium 2.5 ml may increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between Botulinum toxin and Artacil Injection Atracurium 2.5 ml, it can be taken if prescribed by a doctor. However, contact a doctor immediately if you experience excessive muscle weakness or trouble breathing, swallowing, or speaking. Do not discontinue any medications without consulting a doctor.
AtracuriumDoxycycline
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Co-administration of Artacil Injection Atracurium 2.5 ml with doxycycline may increase the risk of breathing problems.

How to manage the interaction:
Although there is an interaction between Artacil Injection Atracurium 2.5 ml and Doxycycline, bit it can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
AtracuriumTobramycin
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Using Artacil Injection Atracurium 2.5 ml with Tobramycin can increase the risk of respiratory depression (breathing disorder).

How to manage the interaction:
Although there is a interaction between Tobramycin and Artacil Injection Atracurium 2.5 ml, but it can be taken if prescribed by a doctor. Do not stop using any medications without talking to your doctor.
AtracuriumClindamycin
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Co-administration of Clindamycin with Artacil Injection Atracurium 2.5 ml can increase the risk of muscle weakness.

How to manage the interaction:
Taking Clindamycin with Artacil Injection Atracurium 2.5 ml together can possibly result in an interaction, but it can be taken if a doctor has advised it. "Clindamycin can affect the muscles and nerves in your body. When used with other medications that also affect the muscles and nerves, it can cause a serious problem called neuromuscular blockade. If you have trouble breathing or can't breathe at all, please call your doctor right away." Do not stop using any medications without a doctor's advice.
AtracuriumColistin
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Coadministration of Artacil Injection Atracurium 2.5 ml with Colistin can increase the risk of Artacil Injection Atracurium 2.5 ml side effects.

How to manage the interaction:
Although there is a possible interaction between Colistin and Artacil Injection Atracurium 2.5 ml, you can take these medicines together if prescribed by your doctor. However, if you experience an upset stomach, rash, dizziness, slurred speech, or fever, consult a doctor. Do not stop using any medications without a doctor's advice.
AtracuriumPolymyxin b
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Co-administration of Polymyxin B with Artacil Injection Atracurium 2.5 ml may cause serious breathing problems

How to manage the interaction:
There may be a possibility of interaction between Polymyxin b and Artacil Injection Atracurium 2.5 ml, but it can be taken if prescribed by a doctor. However, if you experience any unusual symptoms, consult the doctor. Do not stop using any medications without a doctor's advice.
AtracuriumStreptomycin
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Co-administration of Streptomycin with Artacil Injection Atracurium 2.5 ml may increase the risk or severity of side effects.

How to manage the interaction:
Co-administration of Streptomycin with Artacil Injection Atracurium 2.5 ml can possibly result in an interaction, but it can be taken if your doctor has advised it. Do not discontinue any medications without first consulting your doctor.
AtracuriumFentanyl
Severe
How does the drug interact with Artacil Injection Artacil Injection Atracurium 2.5 ml 2.5 ml:
Combining Artacil Injection Atracurium 2.5 ml with Fentanyl can increase the risk of irregular heart rhythm and low blood pressure.

How to manage the interaction:
There may be a possibility of interaction between Artacil Injection Atracurium 2.5 ml and Fentanyl, but it can be taken if prescribed by a doctor. Do not stop using any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Avoid freezing and hot temperatures.

  • Avoid wearing tight-fitting clothes. Instead, wear loose garments.

  • Rest well, and get plenty of sleep.

  • To avoid developing pressure sores, change your position every two hours.

  • Hot or cold therapy can help treat muscle spasms. Apply an ice pack or hot pack on the muscle for 15-20minutes.

  • Stay hydrated, and drink plenty of water.

Habit Forming

No

Therapeutic Class

MUSCLE RELAXANTS/SKELETAL MUSCLE RELAXANTS

Artacil Injection Atracurium Substitute

Substitutes safety advice
  • ACRIS 25MG INJECTION 2.5ML

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  • Atrapure 25 mg Injection 2.5 ml

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Author Details

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Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Artacil Injection Atracurium contains 'Atracurium' that relaxes the muscles by blocking the impulses from the nerves. It is used for skeletal muscle relaxation during surgery.

Artacil Injection Atracurium causes sleepiness and drowsiness. So, drive only if you are alert and omit driving or operating machinery if you feel sleepy or drowsy.

Artacil Injection Atracurium is safe and effective when administered to patients with severe heart disease. However, rapid administration of large doses may occasionally produce transient hypotension in patients with heart problems. Please consult your doctor. Your doctor will prescribe only if the benefits outweigh the risks.

Do not use Artacil Injection Atracurium have had myasthenia gravis or Eaton-Lambert syndrome,  severe electrolyte disorder, asthma-like symptoms (a history of allergy, asthma or bronchospasm), burns, and lack of adequate circulatory filling (hypovolaemia), pregnant or breastfeeding mother. Avoid driving or performing hazardous tasks until you know how Artacil Injection Atracurium will affect you, and your reactions could be impaired.

Artacil Injection Atracurium is a cold chain medicine, and so it has to be stored in the refrigerator between 2-8 degrees Celsius else its efficiency might get lost. Do not store in the freezer or the fridge.

Drug-Drug Interactions Checker List

  • POLYMYXIN B
  • TETRACYCLINE
  • LINCOMYCIN
  • CLINDAMYCIN
  • VANCOMYCIN
  • LIDOCAINE
  • PROCAINAMIDE
  • QUININE
  • FUROSEMIDE
  • ACETAZOLAMIDE
  • PROPRANOLOL
  • DILTIAZEM
  • NIFEDIPINE
  • VERAPAMIL
  • CARBAMAZEPINE
  • PHENYTOIN
  • CHLOROQUINE
  • PENICILLAMINE
  • BECLOMETASONE
  • BUDESONIDE
  • PREDNISOLONE
  • FLUTICASONE
  • MOMETASONE
  • TRIAMCINOLONE
  • DANTROLENE
  • KETAMINE
  • LITHIUM
  • CHLORPROMAZINE
  • SPECTINOMYCIN
  • MANNITOL
  • TRIMETAPHAN
  • HEXAMETHONIUM

Special Advise

An experienced healthcare professional must only give Artacil Injection Atracurium under carefully controlled conditions.

Disease/Condition Glossary

Muscle spasm (contraction): It is the sudden involuntary contractions of the muscle, which can be painful and uncomfortable. When the nerve impulses that control the muscle movements are damaged or interrupted, it could lead to muscle spasms. Symptoms include muscle tightness, joint stiffness, unusual posture, difficulty moving, and pain in affected muscles and joints. Muscle relaxants can treat muscle spasms. Muscle relaxants sedate the muscle and help in inhibiting painful contractions. Muscle weakness is common in the surgical intensive care unit (ICU). Surgical procedures can affect the respiratory muscles through many mechanisms, including thoracoabdominal mechanics (affecting the thorax and the abdomen), reflexes, neuromechanical coupling, and loss of muscular integrity. Impairment of respiratory muscle function after surgery may lead to postoperative complications such as hypoventilation (a state in which a reduced amount of air enters the lungs), hypoxia (an absence of enough oxygen in the tissues), atelectasis (Complete or partial collapse of a lung), and infections, some of which may be life-threatening.

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