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Written By Divya L , PharmaD
Reviewed By Sunny S , MBBS
Non returnable*
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Synonym :

ATORVASTATIN+S AMLODIPINE

Manufacturer/Marketer :

Emcure Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

About Asomex CV 5 mg/10 mg Tablet

Asomex CV 5 mg/10 mg Tablet is a combination of cholesterol-lowering agent and anti-hypertensive agent, primarily used to treat high blood pressure, chest pain (angina) and coronary artery disease (clogged arteries). It lower raised bad cholesterol levels (low-density lipoprotein - LDL), triglycerides (TG) and increases good cholesterol levels (high-density lipoprotein - HDL) in the body. A heart attack occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries).

Asomex CV 5 mg/10 mg Tablet is composed of two medicines, namely: Atorvastatin and Amlodipine. Atorvastatin belongs to the class of drugs known as statins or HMG-CoA reductase inhibitor. It works by blocking liver enzymes, causing the liver to make less cholesterol. Amlodipine belongs to the class of 'calcium channel blockers' and is used to treat high blood pressure, Prinzmetal's or variant angina (chest pain) and other conditions caused by coronary artery disease. It relaxes blood vessels, so that blood passes through them easily, thereby lowers the blood pressure. Thus, Asomex CV 5 mg/10 mg Tablet lowers the risk of stroke and heart attack in people with diabetes and coronary heart disease with raised cholesterol level. 

Your doctor will advise you how often you take Asomex CV 5 mg/10 mg Tablet based on your medical condition. The common side effects of Asomex CV 5 mg/10 mg Tablet include nausea, stomach pain, headache, sleepiness, ankle swelling, flushing (warm sensation in the face, ears, neck and trunk), palpitations (pounding heartbeat), constipation, muscle pain and tiredness. These side effects do not occur in everyone using Asomex CV 5 mg/10 mg Tablet and may vary individually. If you notice any side effects that are not manageable, it is advised to consult your doctor.

Try not to stop taking this medicine of your own. Stopping Asomex CV 5 mg/10 mg Tablet may worsen your condition and increase the risk of a future heart attack. Let your doctor know if are sensitive to Asomex CV 5 mg/10 mg Tablet and have any kidney/liver diseases and heart problems like aortic/mitral stenosis (reduced blood flow from left atrium to the left ventricle due to narrowing of the mitral valve). Asomex CV 5 mg/10 mg Tablet is not recommended for use in pregnancy and breastfeeding. Asomex CV 5 mg/10 mg Tablet may cause dizziness, hence it is advised to drive only when you are mentally alert.

Uses of Asomex CV 5 mg/10 mg Tablet

High blood pressure (hypertension), Chest pain (angina), and Coronary artery disease (clogged arteries).

Directions for Use

Swallow Asomex CV 5 mg/10 mg Tablet as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Asomex CV 5 mg/10 mg Tablet is used to treat myocardial infarction (heart attack), stroke or coronary artery disease. It also lowers abnormally elevated bad cholesterol or fat levels and raises good cholesterol levels in the body. Asomex CV 5 mg/10 mg Tablet is composed of Atorvastatin and Amlodipine. Atorvastatin is a cholesterol-lowering agent and HMG-CoA reductase inhibitor. It works by blocking liver enzymes, causing the liver to make less cholesterol. Atorvastatin reduces the risk of coronary events, such as heart attack, stroke and angina (chest pain). Amlodipine is a calcium channel blocker that relaxes blood vessels, so that blood passes through them easily, thereby lowering the blood pressure. It treats high blood pressure, Prinzmetal's or variant angina (chest pain) and coronary artery disease conditions. Amlodipine also improves blood supply to the heart muscle to receive more oxygen and thus preventing chest pain. Asomex CV 5 mg/10 mg Tablet helps lower cholesterol and blood pressure, thereby preventing a heart attack, stroke and other peripheral vascular diseases. 

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

It is important to tell your doctor if you have any kidney/liver diseases, muscle pain, diabetes, thyroid disorders, alcohol use, and heart problems (aortic/mitral stenosis) before using Asomex CV 5 mg/10 mg Tablet. The patient should inform the doctor if he/she is taking Asomex CV 5 mg/10 mg Tablet before any surgery is scheduled or any new medicine is taken. Asomex CV 5 mg/10 mg Tablet can have harmful effects on the baby when a pregnant mother uses it. Also, Asomex CV 5 mg/10 mg Tablet can pass into the breast milk and may affect the breastfed infants. Asomex CV 5 mg/10 mg Tablet is contraindicated during pregnancy and breastfeeding. Asomex CV 5 mg/10 mg Tablet may cause dizziness, headaches, nausea or tiredness that can affect your ability to drive; hence drive or operate machinery only when you are alert. Avoid alcohol intake while using Asomex CV 5 mg/10 mg Tablet since it may lead to increased blood pressure and further worsening of side effects. Asomex CV 5 mg/10 mg Tablet should be used in children only under a doctor's supervision. 

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
AtorvastatinPosaconazole
Critical

Drug-Drug Interactions

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AmlodipineDantrolene
Critical
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Using Asomex CV 5 mg/10 mg Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Asomex CV 5 mg/10 mg Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
AtorvastatinPosaconazole
Critical
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Taking Asomex CV 5 mg/10 mg Tablet with Posaconazole can increase the blood levels of Asomex CV 5 mg/10 mg Tablet. This can increase the risk of side effects.

How to manage the interaction:
Although there is an interaction between posaconazole with Asomex CV 5 mg/10 mg Tablet, they can be taken together if advised by your doctor. However, contact the doctor if you experience unexplained muscle pain, weakness, fever, chills, joint pain or swelling, unusual bleeding, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark coloured urine, or yellowing of the skin or eyes. Do not discontinue any medications without consulting a doctor.
AmlodipinePrimidone
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Using Asomex CV 5 mg/10 mg Tablet and primidone together may lower Asomex CV 5 mg/10 mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Asomex CV 5 mg/10 mg Tablet with primidone can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineRifampicin
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Coadministration of Asomex CV 5 mg/10 mg Tablet and rifampicin together may lower Asomex CV 5 mg/10 mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although there is an interaction between Asomex CV 5 mg/10 mg Tablet and rifampicin, they can be taken together if prescribed by a doctor. Do not discontinue any medications without consulting a doctor.
AmlodipineSimvastatin
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Taking simvastatin with Asomex CV 5 mg/10 mg Tablet may result in considerably higher blood levels of simvastatin and may increase the risk of side effects (liver damage and rhabdomyolysis - an uncommon but serious illness characterized by the breakdown of skeletal muscle tissue).

How to manage the interaction:
Although taking Asomex CV 5 mg/10 mg Tablet with simvastatin can result in an interaction, it can be taken if a doctor has advised it. If you have unexplained muscular pain, soreness, or weakness while using simvastatin, especially if these symptoms are accompanied by fever or dark-colored urine, consult the doctor immediately. However, if you develop a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without a doctor's advice.
AmlodipineEnzalutamide
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Using a combination of Asomex CV 5 mg/10 mg Tablet and enzalutamide may drastically lower Asomex CV 5 mg/10 mg Tablet blood levels, making the medicine less effective.

How to manage the interaction:
Taking Asomex CV 5 mg/10 mg Tablet with enzalutamide can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.
AmlodipineItraconazole
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Coadministration of Asomex CV 5 mg/10 mg Tablet with itraconazole may significantly raise the blood levels and effects of Asomex CV 5 mg/10 mg Tablet.

How to manage the interaction:
Asomex CV 5 mg/10 mg Tablet and itraconazole may interact, but if prescribed by a doctor, they can be used together. Consult a doctor if you develop chest discomfort, trouble breathing, dizziness or fainting, swelling of the hands, ankles, or feet, or any other of these symptoms. Without consulting a doctor, never stop taking any medication.
AmlodipineNitisinone
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Coadministration of Asomex CV 5 mg/10 mg Tablet and Nitisinone may increase the blood levels and effects of Nitisinone.

How to manage the interaction:
Taking Nitisinone with Asomex CV 5 mg/10 mg Tablet together can result in an interaction, but it can be taken if a doctor has advised it. If you notice any of these symptoms or if you feel unwell after taking your medication, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AmlodipineLemborexant
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Coadministration of lemborexant and Asomex CV 5 mg/10 mg Tablet may increase the blood levels of lemborexant.

How to manage the interaction:
Although co-administration of Asomex CV 5 mg/10 mg Tablet with Lemborexant can result in an interaction, it can be taken if a doctor has advised it. However, consult your doctor if you experience abnormal sleep patterns, worsening of depression, changes in heartbeat, or headache. Do not discontinue any medications without consulting a doctor.
AmlodipineMitotane
Severe
How does the drug interact with Asomex CV 5 mg/10 mg Tablet:
Using Asomex CV 5 mg/10 mg Tablet and mitotane together may drastically lower Asomex CV 5 mg/10 mg Tablet blood levels, which makes the medicine less effective.

How to manage the interaction:
Although co-administration of Asomex CV 5 mg/10 mg Tablet with mitotane can result in an interaction, it can be taken if a doctor has advised it. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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AMLODIPINE-5MG+ATORVASTATIN-10MGFruit juices
Moderate

Drug-Food Interactions

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AMLODIPINE-5MG+ATORVASTATIN-10MGFruit juices
Moderate
Common Foods to Avoid:
Grapefruit Juice, Pineapple Juice, Pomegranate Juice, Noni Juice, Orange Juice, Cranberry Juice

How to manage the interaction:
Consumption of grape juice can increase the blood levels of atorvastatin and causes side effects. Avoid taking grape juice with atorvastatin as it can lead to an interaction, You should also seek immediate medical attention if you develop fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark colored urine, and/or yellowing of the skin or eyes, Do not stop using any medications without a doctor's advice.

Diet & Lifestyle Advise

  • Take the medication as directed by the doctor and at regular intervals. Do not use other over the counter medications, herbal or vitamin supplements without informing your pharmacist or doctor when you take Asomex CV 5 mg/10 mg Tablet.
  • Low cholesterol diet and regular exercise regime are found to complement treatment with Asomex CV 5 mg/10 mg Tablet effectively. 
  • Keep your cholesterol and triglyceride levels under control.
  • Eat at regular intervals and maintain a healthy diet that includes fresh fruits, vegetables.
  • High-fat meal should be avoided as it may further increase the risk of heart attack and instead eat heart-healthy foods.
  • Limit alcohol intake since it raises blood pressure and increases the risk of heart diseases.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Your doctor also guides you on noticing and managing the early symptoms of detecting heart diseases. 

Habit Forming

No

Therapeutic Class

CARDIOVASCULAR AGENTS

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Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Asomex CV 5 mg/10 mg Tablet lowers the bad cholesterol levels and increases good cholesterol levels in the blood, preventing fat accumulation in blood vessels. It also decreases the blood pressure by widening the blood vessels and thus pumping blood to the heart. Thereby, Asomex CV 5 mg/10 mg Tablet helps treat high blood pressure, stroke, chest pain (angina) and coronary artery disease (clogged arteries).

Let your doctor know if you have any kidney/liver diseases, muscle pain, diabetes, thyroid disorders, alcohol use and heart problems (aortic/mitral stenosis) before taking Asomex CV 5 mg/10 mg Tablet. Also please inform your doctor if you have any medical issues before commencing Asomex CV 5 mg/10 mg Tablet.

Asomex CV 5 mg/10 mg Tablet can cause dizziness as one of its side effects. Please consult your doctor if you feel dizzy for a longer time. To reduce dizziness and light-headedness symptoms, it is advised to get up slowly when you rise from a sitting or lying position. Avoid driving or operating machinery during episodes of dizziness.

It is advised to limit or avoid the intake of foods high in fat or cholesterol while using Asomex CV 5 mg/10 mg Tablet. This kind of foods may decrease the efficacy of Asomex CV 5 mg/10 mg Tablet. Also please avoid taking grapefruit and its products since it may produce unwanted effects with Asomex CV 5 mg/10 mg Tablet. Red yeast rice products are also not recommended while using Asomex CV 5 mg/10 mg Tablet since they may increase muscle and liver problems.

Nitroglycerine is a blood pressure-lowering agent so if you are using this, let your doctor know about this before using Asomex CV 5 mg/10 mg Tablet.

Take the missed dose as soon as possible. However, if it is time for the next dose, skip the missed dose and go back to your regular dosing schedule. Do not double the dose.

Drug-Drug Interactions Checker List

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  • IBUPROFEN
  • NAPROXEN

Special Advise

  • Please consult your doctor and mention that you are using Asomex CV 5 mg/10 mg Tablet before undergoing a dental procedure or any surgery. 
  • Monitoring your heart health with an occasional ECG will be helpful.
  • Please keep a check on your cholesterol levels (HDL, LDL) in blood with timely blood examinations.
  • Your doctor may advice regular monitoring of blood glucose levels.

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. Blood pressure is defined as the amount of blood pumped by the heart and the amount of resistance exerted by the arteries against the blood flow. If the heart pumps more blood, then arteries become narrower and in turn, blood pressure becomes high. If blood pressure becomes uncontrolled, it may lead to serious heart diseases, including stroke and heart attack.

Heart attack: It occurs when a blood clot blocks the blood flow to the heart. This blockage of arteries is often an accumulation of fat, cholesterol and other substances, which form a plaque in the arteries that feed the heart (coronary arteries). During a heart attack (myocardial infarction), the blood supply which nourishes the heart with oxygen is cut off. Heart attack signs include chest pain, upper body pain, sweating, nausea, fatigue and trouble breathing.

Stroke: It occurs when there is a blockage of blood supply to part of the brain that prevents brain tissues from getting enough oxygen and nutrients.

Hyperlipidaemia or dyslipidemia: It occurs when there is an excess of the unhealthy balance of cholesterol in the blood. When there is a high cholesterol level in the blood, your arteries get narrowed and clogged that finally contributes to heart diseases, like stroke and heart attack. Eating high-fat or high-cholesterol containing food/drinks and genetic factors are the primary causes of high cholesterol.

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