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Emcure Pharmaceuticals Ltd

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ORAL

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About Asomex OH Tablet

Asomex OH Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. High blood pressure is a chronic condition in which the blood's force against the artery wall is high. As a result, it increases the risk of heart-related diseases like heart attack, heart failure, stroke, irregular heartbeat, and other complications.

Asomex OH Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Asomex OH Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Depending upon your medical condition, you are advised to take Asomex OH Tablet for as long as your doctor has prescribed it for you. The most common side effects of Asomex OH Tablet are nausea, upset stomach, dehydration, headache, diarrhoea, electrolyte imbalance, headache, feeling exhausted, swollen ankles, dizziness, and decreased blood pressure in some cases. Most of these side effects of Asomex OH Tablet do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Do not use potassium supplements or salt substitutes unless your doctor tells you. In rare cases, Asomex OH Tablet can cause a condition that results in a skeletal muscle problem, leading to further kidney failure. If you notice unexplained muscle pain, dark-coloured urine, tenderness, or weakness, especially if you also have a fever or unexplained tiredness, immediately contact the doctor. Try not to stop taking this medicine of your own. Let your doctor know about this, as it may cause a rise in blood pressure and increase heart disease and stroke risk. Inform your doctor if you are suffering from kidney, liver, heart disease, or diabetes. If you are pregnant or breastfeeding, do not take Asomex OH Tablet as it is a category D pregnancy drug and may harm the baby. Do not use the Asomex OH Tablet if you cannot urinate, are dehydrated, have low blood pressure (hypotension), or have had cardiogenic shock (sudden stopping blood flow to the heart). Please tell your doctor if you are taking any other medicines or are allergic to this medicine. Reducing table salt (sodium chloride) in your food often helps lower blood pressure.

Uses of Asomex OH Tablet

Hypertension (high blood pressure)

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Asomex OH Tablet belongs to a group of medications called 'anti-hypertensives' primarily used for lowering high blood pressure (hypertension) by removing extra fluid (electrolytes) from the body. Asomex OH Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil is a prodrug and breaks down into active form, i.e., olmesartan once absorbed in the GIT (Gastrointestinal tract). An angiotensin receptor blocker (ARB) blocks the hormone angiotensin, thereby relaxing and widening the narrowed blood vessels. Amlodipine is a calcium channel blocker; it reduces the heart's workload and makes it more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Asomex OH Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

Do not use Asomex OH Tablet if you are pregnant, planning for pregnancy, or unable to urinate (anuria). If you have diabetes and taking Asomex OH Tablet with other blood pressure-lowering pills like 'aliskiren,' immediately stop taking both together and consult a doctor. Besides this, it is contraindicated in low blood pressure (hypotension), cardiogenic shock (sudden stopping of blood flow to the heart), and aortic stenosis (heart valve problem). Asomex OH Tablet may pass into breast milk, so before starting Asomex OH Tablet , either you need to stop nursing or you should not take Asomex OH Tablet while breastfeeding. Please inform your doctor before surgery if you are taking Asomex OH Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia. Avoid potassium salt or its substitute intake while using Asomex OH Tablet to avoid any electrolyte imbalance. Asomex OH Tablet can pass into breast milk, but its effect on the baby is unknown. So, it is better to tell your doctor if you take Asomex OH Tablet and breastfeeding.

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
AmlodipineDantrolene
Critical

Drug-Drug Interactions

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Olmesartan medoxomilAliskiren
Critical
How does the drug interact with Asomex OH Tablet:
Using aliskiren together with olmesartan may increase the risk of serious side effects (kidney problems, low blood pressure, and high potassium levels in the blood).

How to manage the interaction:
Taking Asomex OH Tablet with Aliskiren is not recommended as it can cause an interaction, they can be taken if advised by a doctor. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat.It is crucial that you continue to consume enough fluids while taking these medications. Do not stop using any medications without consulting a doctor.
AmlodipineDantrolene
Critical
How does the drug interact with Asomex OH Tablet:
Using Asomex OH Tablet together with dantrolene may increase the risk of hyperkalemia (high blood potassium).

How to manage the interaction:
Taking Asomex OH Tablet with Dantrolene can cause an interaction, consult a doctor before taking it. You should seek medical attention if you experience nausea, vomiting, weakness, confusion, tingling of the hands and feet, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
HydrochlorothiazideDofetilide
Critical
How does the drug interact with Asomex OH Tablet:
Taking Dofetilide and Asomex OH Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Dofetilide and Asomex OH Tablet together is not recommended as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, chest pain or tightness, rapid heartbeat, or memory loss, contact your doctor immediately. Do not discontinue any medications without consulting a doctor.
HydrochlorothiazideCisapride
Critical
How does the drug interact with Asomex OH Tablet:
Taking Cisapride and Asomex OH Tablet can increase the risk of an irregular heart rhythm which can be severe. The risk increases in patients with a history of heart illness or electrolyte imbalance.

How to manage the interaction:
Combining Cisapride and Asomex OH Tablet together is generally avoided as it can possibly result in an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, or fast or pounding heartbeats, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
Olmesartan medoxomilFosinopril
Severe
How does the drug interact with Asomex OH Tablet:
Coadministration of Asomex OH Tablet with fosinopril may cause low blood pressure, kidney problems, and may increase potassium levels in the blood.

How to manage the interaction:
Although taking Asomex OH Tablet together with fosinopril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilRamipril
Severe
How does the drug interact with Asomex OH Tablet:
Taking ramipril together with olmesartan may increase the risk of side effects (blood pressure, kidney function impairment, and a condition called Hyperkalemia - high blood potassium).

How to manage the interaction:
Although taking Asomex OH Tablet with ramipril may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilpotassium phosphate
Severe
How does the drug interact with Asomex OH Tablet:
Using potassium phosphate together with olmesartan may significantly increase potassium levels in the blood.

How to manage the interaction:
Although taking Asomex OH Tablet and potassium phosphate together can cause an interaction, it can be taken if a doctor has suggested it. However if you experience symptoms such as nausea, vomiting, weakness, confusion, tingling of the hands and feet, feelings of heaviness in the legs, a weak pulse, or a slow or irregular heartbeat, consult a doctor. It is crucial that you continue to consume enough fluids while taking these medications. Do not discontinue any medications without consulting a doctor.
Olmesartan medoxomilEnalapril
Severe
How does the drug interact with Asomex OH Tablet:
Coadministration of Asomex OH Tablet with enalapril can elevate the risk of adverse effects such as low blood pressure, kidney impairment, and hyperkalemia (high blood potassium). Hyperkalemia can cause kidney failure, strong paralysis, abnormal heart rhythm, and cardiac arrest in extreme instances. If you are elderly, dehydrated, or have renal disease, diabetes, or severe heart failure, you are more prone to develop hyperkalemia while taking these medications.

How to manage the interaction:
Although taking Asomex OH Tablet together with enalapril may result in an interaction, they can be taken together if prescribed by your doctor. However, contact your doctor immediately if you experience signs and symptoms of hyperkalemia, such as nausea, vomiting, confusion, numbness, tingling in hands and feet, and irregular heartbeat. It is advised to limit the intake of potassium-rich foods like tomatoes, bananas, mangoes, beans, and potassium-containing supplements. Do not discontinue any medication without consulting your doctor.
Olmesartan medoxomilPotassium iodide
Severe
How does the drug interact with Asomex OH Tablet:
Coadministration of Asomex OH Tablet with potassium iodide may increase potassium levels in the blood. (High potassium levels can cause hyperkalemia, which can lead to kidney failure, muscular paralysis, abnormal heart rhythm, and cardiac arrest in extreme cases).

How to manage the interaction:
Although taking Asomex OH Tablet together with potassium iodide may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.
Olmesartan medoxomilPotassium chloride
Severe
How does the drug interact with Asomex OH Tablet:
Using Asomex OH Tablet with Potassium chloride may increase Potassium levels in the blood.

How to manage the interaction:
Although taking Asomex OH Tablet together with Potassium chloride may lead to an interaction but can be taken if prescribed by the doctor. However, consult the doctor if you experience nausea, vomiting, weakness, disorientation, tingling in your hands and feet, feelings of heaviness in your legs, a weak pulse, or a slow or irregular heartbeat. It is important to maintain proper fluid intake while taking these medications. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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OLMESARTAN MEDOXOMIL-20MG+AMLODIPINE-2.5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate

Drug-Food Interactions

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OLMESARTAN MEDOXOMIL-20MG+AMLODIPINE-2.5MG+HYDROCHLOROTHIAZIDE-12.5MGPotassium rich foods
Moderate
Common Foods to Avoid:
Lentils, Orange Juice, Oranges, Raisins, Potatoes, Salmon Dried, Spinach, Sweet Potatoes, Tomatoes, Coconut Water, Beans, Beetroot, Broccoli, Bananas, Apricots, Avocado, Yogurt

How to manage the interaction:
Taking Asomex OH Tablet with potassium-containing salt substitutes or potassium supplements can cause high levels of potassium in the blood. Avoid taking potassium-containing salt substitutes or potassium supplements while being treated with Asomex OH Tablet.

Diet & Lifestyle Advise

  • Create a well-balanced and healthy diet that includes vegetables, fruits, whole grains, legumes, omega-3-rich foods, and lean protein sources.
  • Keep your weight under control with a BMI of 19.5-24.9.
  • Avoid chronic stress, as it can raise your blood pressure.
  • Spend time with your loved ones to cope with stress and practice mindfulness techniques.
  • Be mindful of salt; consume no more than 2,300 mg each day.
  • Limit or avoid alcohol consumption.
  • Quitting smoking is the best strategy to lower the risk of heart disease.

Habit Forming

No

Therapeutic Class

ANTI- HYPERTENSIVES

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Asomex OH Tablet is a combination of three medicines: Olmesartan medoximil, Amlodipine, and Hydrochlorothiazide. Olmesartan medoximil relaxes and widens the narrowed blood vessels. Amlodipine reduces the heart's workload and makes the heart more efficient at pumping blood throughout the body. Hydrochlorothiazide is a diuretic or water pill that removes extra water/fluid and certain electrolyte overload from the body. Together, Asomex OH Tablet lowers fluid overload, raises blood pressure, improves blood flow, and reduces the future risk of a heart attack and stroke.

Asomex OH Tablet can be safely taken as long as your doctor prescribes it. Conditions such as high blood pressure are life-long conditions, and one should not abruptly discontinue it without discussing it with a doctor. Discontinuing Asomex OH Tablet may lead to increased blood pressure and a high risk of heart attack and stroke.

It's unlikely that Asomex OH Tablet affects fertility in men or women. However, in some cases, some water pills like hydrochlorothiazide may lead to erectile dysfunction. For the best advice, please consult your doctor.

Please inform your doctor before surgery if you are taking Asomex OH Tablet as it needs to be stopped because it might lower the blood pressure further if taken along with local anaesthesia.

Do not use Asomex OH Tablet if you are pregnant, planning for pregnancy, or unable to urinate. If you have diabetes and taking Asomex OH Tablet with other blood pressure-lowering pills like 'aliskiren', immediately stop taking both together and consult a doctor.

High blood pressure during pregnancy is called 'Pregnancy-induced hypertension (PIH). It is harmful to both the baby and the mother. In the mother, very high blood pressure can cause seizures (fits), headache, swelling of feet, kidney damage, and a higher risk of bleeding during pregnancy and delivery. This can also affect the baby by causing abnormal fetal heart rate, risk of stillbirth, and a small baby. So, during pregnancy, you should have regular blood pressure monitoring. Visit your Obstetrician if you have any concerns about blood pressure during pregnancy.

Yes, Asomex OH Tablet is known to cause ankle swelling (oedema) upon long-term use as Asomex OH Tablet amlodipine. Please try to keep your feet up when sitting for long hours. If the problem persists still, consult your doctor and do as advised.

Drug-Drug Interactions Checker List

  • LITHIUM
  • DIGOXIN
  • ASPIRIN
  • METFORMIN
  • INSULIN
  • SILDENAFIL
  • SIMVASTATIN
  • CYCLOSPORINE
  • ATENOLOL
  • ALISKIREN
  • ENALAPRIL
  • LISINOPRIL
  • RAMIPRIL
  • METOPROLOL
  • IBUPROFEN
  • CARBENOXOLONE

Disease/Condition Glossary

Hypertension: It is a chronic condition when blood pressure is too high. This condition can lead to hardened arteries (blood vessels), decreasing the blood and oxygen flow to the heart. Blood pressure is the measurement of the force our heart uses to pump blood to all body parts. Raised blood pressure can cause chest pain (angina) and heart attack (when the blood supply to the heart is blocked). High blood pressure also causes brain damage (stroke) and kidney failure. High blood pressure can be diagnosed with the help of a blood pressure monitor or sphygmomanometer. Systolic pressure is the pressure when the heart pumps blood out. On the other hand, diastolic pressure is when your heart is at the resting stage between heartbeats. If your blood pressure is 140/90 mm of Hg, it means the systolic pressure is 140 mm of Hg, and diastolic pressure is 90 mm of Hg. Ideal blood pressure should be between 90/60 mm of Hg and 120/80 mm of Hg.

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