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Written By Veda Maddala , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD

About Aspezex 10000 Injection 1's

Aspezex 10000 Injection 1's belongs to the class of medicines called antineoplastic (anticancer) agents used in the treatment of acute lymphoblastic leukaemia (a type of blood and bone marrow cancer). Acute lymphoblastic leukaemia (ALL) is the most common childhood cancer. It is a type of blood cancer which causes excessive production of lymphocytes (a type of white blood cells) by the bone marrow.

Aspezex 10000 Injection 1's contains L Asparaginase which works by lowering asparagine levels in the body, which is necessary for the survival of cancer cells. Thus, Aspezex 10000 Injection 1's stops the cancer cells from dividing and growing. 

Aspezex 10000 Injection 1's will be administered by a healthcare professional; do not self-administer. Sometimes, Aspezex 10000 Injection 1's may cause common side effects such as nausea, weight loss, generalised pain or muscle pain, infections or a decrease in normal blood content. Most of these side effects of Aspezex 10000 Injection 1's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to L asparaginase or other medicines, please tell your doctor. You are recommended to avoid breastfeeding during treatment with Aspezex 10000 Injection 1's as there may be a risk to the feeding child. If you are pregnant or planning pregnancy, please inform your doctor before receiving Aspezex 10000 Injection 1's. Also, you are recommended to use effective contraceptive methods before and for at least 3 months after treatment with Aspezex 10000 Injection 1's to prevent pregnancy. Aspezex 10000 Injection 1's is given to children in doses as advised by the doctor, depending on the age. Avoid driving after receiving Aspezex 10000 Injection 1's as it may cause drowsiness or dizziness.

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Non returnable*
COD available

Online payment accepted

Consume Type

PARENTERAL

Return Policy

Not Returnable

for this medicine

Uses of Aspezex 10000 Injection 1's

Acute lymphoblastic leukaemia

Medicinal Benefits

Aspezex 10000 Injection 1's contains L Asparaginase, an anticancer agent used in the treatment of acute lymphoblastic leukaemia (a type of blood and bone marrow cancer). It lowers the levels of asparagine in the body, which is necessary for the survival of cancer cells. Thus, Aspezex 10000 Injection 1's stops the cancer cells from dividing and growing. 

Side Effects of Aspezex 10000 Injection 1's

  • Nausea
  • Vomiting
  • Weight loss
  • Generalised pain or muscle pain
  • Infections
  • Swelling at the injection site
  • loss of appetite
  • headache
  • lack of energy
  • drowsiness
  • Stomach cramps

Directions for Use

Aspezex 10000 Injection 1's will be administered by a healthcare professional; do not self-administer.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to L asparaginase or any other medicines, please tell your doctor. You are recommended to avoid breastfeeding during treatment with Aspezex 10000 Injection 1's as there may be a risk to the feeding child. If you are pregnant or planning for pregnancy, please inform your doctor before receiving Aspezex 10000 Injection 1's. Also, you are recommended to use effective contraceptive methods before and for at least three months after treatment with Aspezex 10000 Injection 1's to prevent pregnancy. Aspezex 10000 Injection 1's is given to children in doses as advised by the doctor, depending on the age. Avoid driving after receiving Aspezex 10000 Injection 1's if you experience drowsiness or dizziness. Aspezex 10000 Injection 1's may increase the risk of infections. Therefore, consult your doctor if you notice any signs of infection and avoid contact with people having viral infections. If you experience any significant bleeding during treatment with Aspezex 10000 Injection 1's, inform your doctor immediately, as Aspezex 10000 Injection 1's may affect your body’s ability to prevent excessive bleeding. 

Therapeutic Class

ANTINEOPLASTIC

Drug-Drug Interactions

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AsparaginaseMipomersen
Severe
AsparaginaseBexarotene
Severe

Drug-Drug Interactions

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AsparaginaseMipomersen
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
Coadministration of Aspezex 10000 Injection 1's and Mipomersen may increase the risk of liver problems.

How to manage the interaction:
Although taking Aspezex 10000 Injection 1's and Mipomersen together can evidently cause an interaction, it can be taken if your doctor has suggested it. Call a doctor immediately if you have fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes. Do not stop using any medications without talking to a doctor.
AsparaginaseBexarotene
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
The use of Aspezex 10000 Injection 1's with bexarotene may raise the risk of inflammation of the pancreas.

How to manage the interaction:
Co-administration of Aspezex 10000 Injection 1's with Bexarotene can result in an interaction, but it can be taken if a doctor has advised it. However, contact a doctor if you have symptoms such as persistent nausea, vomiting, abdominal soreness, and upper abdominal pain, especially if it worsens after eating or extends to the back. Do not stop using any medications without talking to a doctor.
AsparaginaseThalidomide
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
Taking thalidomide together with Aspezex 10000 Injection 1's may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Aspezex 10000 Injection 1's together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
AsparaginaseNatalizumab
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
Taking Aspezex 10000 Injection 1's with Natalizumab together can increase the risk of developing serious infections.

How to manage the interaction:
Taking Aspezex 10000 Injection 1's with Natalizumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience fever, chills, diarrhea, sore throat, muscle pains, breathing difficulty, blood in your coughing fluid, weight loss, red or irritated skin, body sores, discomfort or burning when you urinate, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory, and personality, consult a doctor. Do not stop using any medications without talking to a doctor.
AsparaginaseLeflunomide
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
Taking Aspezex 10000 Injection 1's with leflunomide may raise the risk of severe infections, and liver problems.

How to manage the interaction:
Although there is an interaction between Aspezex 10000 Injection 1's and leflunomide, they can be taken together if prescribed by a doctor. However, consult a doctor if you experience fatigue, dizziness, lightheadedness, unusual bleeding or bruising, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Do not discontinue any medications without consulting a doctor.
AsparaginaseLomitapide
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
Coadministration of Aspezex 10000 Injection 1's and Lopitamide may increase the risk of liver issues.

How to manage the interaction:
Taking Aspezex 10000 Injection 1's with Lomitapide together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience a fever, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, abdominal pain, dark urine, pale stools, and/or yellowing of the skin or eyes, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
AsparaginaseTeriflunomide
Severe
How does the drug interact with Aspezex 10000 Injection 1's:
The use of Aspezex 10000 Injection 1's in conjunction with teriflunomide may raise the risk of severe infections, liver problems.

How to manage the interaction:
Co-administration of Aspezex 10000 Injection 1's with Teriflunomide can result in an interaction, but it can be taken if a doctor has advised it. However, If you experience fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes, consult the doctor. Do not stop using any medications without talking to a doctor.
AsparaginaseDalteparin
Moderate
How does the drug interact with Aspezex 10000 Injection 1's:
Using dalteparin with Aspezex 10000 Injection 1's may increase your risk of blood clots or bleeding.

How to manage the interaction:
Although taking Desogestrel and Fosamprenavir together can cause an interaction, it can be taken if your doctor has suggested it. However, if you experience fast heartbeat, anxiety, constipation, cough, dark urine, diarrhea, dizziness, lightheadedness, fainting, fever, hives or welts, itching skin or rash call your doctor right away. Do not discontinue any medications without first consulting your doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • CYTARABINE
  • METHOTREXATE
  • VINCRISTINE
  • PREDNISONE

Diet & Lifestyle Advise

  • Maintain a balanced diet including fruits and vegetables rich in nutrients and low-fat proteins like lean meats, fish and poultry.
  • Drink plenty of water daily during treatment with Aspezex 10000 Injection 1's, as some cancer therapies may cause dehydration.
  • Exercise regularly and maintain a healthy body weight.
  • Regularly wash your hands and avoid contact with people having infections.
  • Quit smoking.

Habit Forming

No

Special Advise

  • Your doctor will monitor you closely during and after treatment with Aspezex 10000 Injection 1's for normal blood content, allergic reactions, and kidney, pancreas and liver functions.

Author Details

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Disease/Condition Glossary

Acute lymphoblastic leukaemia (ALL): It is a type of blood cancer which causes excessive production of lymphocytes (a type of white blood cells) by the bone marrow. It is the most common childhood cancer. The symptoms include bleeding from gums, weakness, bone pain, joint pain, bruises, extreme tiredness, paleness, enlarged lymph nodes in the neck, groin region or under the arms, fever or shortness of breath. The risk factors include exposure to high levels of radiation, viral infections, inherited syndromes, smoking, prolonged exposure to certain chemicals or chemotherapy drugs or even diesel.

Aspezex 10000 Injection 1's Substitute

Substitutes safety advice
  • Celginase 10000 Injection 1's

    by Others

    1613.30per tablet
  • L-Ginase 10000 IU Injection 1's

    by Others

    1484.10per tablet
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