Astriol Tablet 10'S
MRP ₹121
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About Astriol Tablet
Astriol Tablet belongs to a group of medicines called ‘vitamin D metabolites’ primarily used to treat low blood calcium levels. Astriol Tablet effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Astriol Tablet can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Astriol Tablet is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.
Astriol Tablet contains Calcitriol (Vitamin D3); it is used to prevent or treat a calcium deficiency. It is an essential nutrient to maintain bone formation and maintenance. Calcitriol is a synthetic version of Vitamin D3 and treats calcium deficiency with hypoparathyroidism (the parathyroid gland's decreased activity) and metabolic bone diseases in people with chronic kidney failure. It raises Vitamin D levels and thereby increases calcium levels in the blood. This helps in improving the absorption rate of calcium from the intestine.
Take Astriol Tablet as prescribed by your doctor. You are advised to take Astriol Tablet for as long as your doctor has prescribed it for you, depending on your medical condition. In some cases, Astriol Tablet can cause side effects like constipation or stomach upset, nausea, vomiting, loss of appetite, mood changes, weakness, tiredness, fast or pounding heartbeat, bone/muscle pain, and headache. Most of these side effects of Astriol Tablet do not require medical attention and gradually resolve over time. However, if these side effects persist longer, please consult your doctor.
If you are known to be allergic to Astriol Tablet or its inactive components, please inform your doctor. Pregnant or breastfeeding women should consult their doctor before taking Astriol Tablet . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Astriol Tablet may pass into the breast milk, hence breastfeeding mothers need to seek medical advice before starting Astriol Tablet . Do not take Astriol Tablet if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food). Inform your doctor if you have any heart/kidney/liver/blood vessel diseases, kidney stones, sarcoidosis (growth of inflammatory cells in different parts of the body), Crohn's disease (inflammatory bowel disease), Whipple's disease (bacterial infection affecting joints and digestive system), achlorhydria (little or no stomach acid), low levels of bile, and phosphate imbalance.
Uses of Astriol Tablet
Directions for Use
Key Benefits
Astriol Tablet effectively treats various conditions caused by low calcium levels in the body, such as osteoporosis (weak and brittle bones), osteomalacia/rickets (weak bones), hypoparathyroidism (low levels of parathyroid hormone), and latent tetany (a muscle disease with low blood calcium levels). Astriol Tablet can also be given to pregnant, nursing, and postmenopausal women to ensure that they are getting enough calcium. Additionally, Astriol Tablet is used to treat hyperparathyroidism (overactive parathyroid glands) and metabolic bone disease in people with chronic kidney disease, surgery, or other conditions.
Storage
- Stay hydrated by drinking plenty of water.
- Avoid dairy product such as cheese, milk, yogurt and ice cream.
- Maintain healthy weight and exercise daily.
- Following a low-calcium diet can help reduce hypercalcemia symptoms.
- Reduce sodium intake to minimize calcium excretion in urine.
- Limit animal protein consumption to decrease urinary calcium levels.
- Increase fluid intake by drinking plenty of water to dilute urine.
- Moderate calcium intake based on individual needs, avoiding drastic restriction.
- Limit oxalate-rich foods like spinach and chocolate to minimize kidney stone formation.
- Stay hydrated by drinking plenty of water.
- Consider reducing vitamin D supplementation if excessive intake is contributing to hypercalciuria.
- Regularly monitor urine calcium levels through 24-hour urine tests.
- Always seek guidance from a healthcare expert prior to implementing substantial changes to your diet or lifestyle routine.
- Inform your doctor about the medication you're taking and the UTI symptoms you're experiencing.
- Your doctor may adjust your medication regimen or consider alternative medications or dosages that may reduce the risk of UTIs.
- Drink plenty of water (at least 8-10 glasses a day) to help flush out bacteria. Avoid sugary drinks and caffeine, which can exacerbate UTI symptoms.
- Urinate when you feel the need rather than holding it in. This can help prevent bacterial growth and reduce the risk of UTIs.
- Consider cranberry supplements: Cranberry supplements may help prevent UTIs by preventing bacterial adhesion.
- Monitor UTI symptoms and report any changes to your doctor.
- If antibiotics are prescribed, take them as directed and complete the full course.
- Hydrate your body: Drink enough water to prevent dehydration and headaches.
- Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
- Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
- Take rest: lie down in a quiet, dark environment.
- Cold or warm compresses can help reduce tension.
- Stay Upright: Maintain good posture to keep symptoms from getting worse.
- To treat headaches naturally, try acupuncture or massage therapy.
- Over-the-counter pain relievers include acetaminophen and ibuprofen.
- Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
- Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
- Frequent Headaches: If you get reoccurring headaches, consult your doctor.
- Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.
- Drink water or other clear fluids.
- To prevent worsening of pain, limit intake of tea, coffee, or alcohol.
- Include bland foods like rice, toast, crackers, and rice in your diet.
- Avoid lying down immediately after eating as it may cause indigestion or heartburn.
- Avoid acidic and spicy food as it may cause indigestion.
- Inform your doctor about the nausea and discuss possible alternatives to the medication or adjustments to the dosage.
- Divide your daily food intake into smaller, more frequent meals to reduce nausea.
- Opt for bland, easily digestible foods like crackers, toast, plain rice, bananas, and applesauce.
- Avoid certain foods that can trigger nausea, such as fatty, greasy, spicy, and smelly foods.
- Drink plenty of fluids, such as water, clear broth, or electrolyte-rich beverages like coconut water or sports drinks.
- Use ginger (tea, ale, or candies) to help relieve nausea.
- Get adequate rest and also avoid strenuous activities that can worsen nausea.
- Talk to your doctor about taking anti-nausea medication if your nausea is severe.
- Record when your nausea occurs, what triggers it, and what provides relief to help you identify patterns and manage your symptoms more effectively.
- Skin rash caused by allergies is due to irritants or allergens. Therefore, avoid contact with such irritants.
- Consult your doctor for proper medication and apply an anti-itch medication. Follow the schedule and use the medication whenever needed.
- Protect your skin from extreme heat and try to apply wet compresses.
- Soak in the cool bath, which gives a soothing impact to the affected area.
Drug Warnings
Before taking Astriol Tablet , inform your doctor if you are undergoing hemodialysis due to kidney problems and have a stent in the heart. Astriol Tablet may alter calcium levels, so it is recommended to regularly monitor calcium levels in the blood and urine. Inform your doctor immediately if you notice fever, increased thirst and urination, dehydration, bedwetting, constipation, and stomach pain, as they may sign very high levels of calcium in your blood. Pregnant or breastfeeding women should consult their doctor before taking Astriol Tablet . Higher doses of Vitamin D than the recommended daily dose should be used in pregnant women only when advised by the doctor. Astriol Tablet may pass into the breast milk, hence breastfeeding mothers need to seek medical advice before starting Astriol Tablet . Do not take Astriol Tablet if you have hypercalcemia (high calcium levels), hypervitaminosis D (high vitamin D levels), and malabsorption syndrome (difficulty absorbing nutrition from food).
Drug-Drug Interactions
Drug-Drug Interactions
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Co-administration of Paricalcitol and Astriol Tablet are forms of vitamin D, and taking too much vitamin D may lead to toxic effects related to excessive calcium levels in the blood and urine.
How to manage the interaction:
Concomitant use of Paricalcitol with Astriol Tablet can lead to an interaction, it can be taken if advised by a doctor. Consult the prescriber if you experience symptoms of vitamin D intoxication such as weakness, fatigue, headache, vertigo, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, metallic taste, muscle pain, bone pain, muscle incoordination, and low muscle tone. Do not discontinue the medication without consulting a doctor.
Co-administration of Astriol Tablet with Dihydrotachysterol can increase the risk of adverse effects.
How to manage the interaction:
Co-administration of Dihydrotachysterol with Astriol Tablet can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - irregular heartbeat, seizures, weakness, tiredness, headache, dizziness, ringing in the ears, loss of appetite, feeling sick, throwing up, constipation, dry mouth, strange taste in your mouth, muscle or bone pain, trouble coordinating movements, weak muscles, peeing a lot, feeling very thirsty, losing weight, eye infection, sensitivity to light, itching, or a higher body temperature - make sure to call a doctor right away. Do not discontinue any medications without consulting a doctor.
Co-administration of Orlistat with Astriol Tablet may reduce the levels of Astriol Tablet which can lead to low treatment outcomes.
How to manage the interaction:
Although there is an interaction, Astriol Tablet can be taken with Orlistat when prescribed by the doctor. Do not discontinue any medications without consulting a doctor.
Co-administration of Metolazone with Astriol Tablet can cause blood calcium levels to become too high.
How to manage the interaction:
Although there is an interaction, Astriol Tablet can be taken with metolazone if prescribed by the doctor. Consult the doctor if you experience symptoms such as dizziness, drowsiness, weakness, lethargy, headache, nausea, vomiting, or seizures. Do not discontinue the medication without consulting a doctor.
Co-administration of Astriol Tablet with Digitoxin may increase the risk or severity of digitoxin toxicity and irregular heart rhythm.
How to manage the interaction:
Although there is an interaction, Astriol Tablet can be taken with Digitoxin if prescribed by the doctor. Consult the prescriber if you experience symptoms that could indicate high blood calcium, such as weakness, fatigue, headache, dizziness, drowsiness, ringing in the ears, loss of appetite, nausea, vomiting, constipation, dry mouth, a metallic taste in the mouth, bone or muscle pain, incoordination, frequent urination, and weight loss. Also, seek medical attention if you experience symptoms of digitoxin toxicity, such as blurred vision, slow pulse, or irregular heartbeats. Do not discontinue the medication without consulting a doctor.
Co-administration of Astriol Tablet and Burosumab may cause increases in phosphorus and vitamin D levels in the blood, which may lead to an increased risk of kidney stones.
How to manage the interaction:
There may be a possibility of interaction between Astriol Tablet and Burosumab, but it can be taken if prescribed by a doctor. If you have any of these symptoms like kidney stones, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Co-administration of Isoniazid with Astriol Tablet may decrease the effects of Astriol Tablet.
How to manage the interaction:
Although there is an interaction, Astriol Tablet can be taken with isoniazid if prescribed by the doctor. Do not stop using any medications without talking to a doctor. Do not discontinue the medication without consulting a doctor.
Co-administration of Astriol Tablet with Carbamazepine may decrease the effects of Astriol Tablet.
How to manage the interaction:
Although there is an interaction, Astriol Tablet can be taken with Carbamazepine if prescribed by the doctor. However, if you experience any unusual symptoms contact your doctor immediately. Do not stop using any medications without first talking to your doctor.
Co-administration of Rifapentine with Astriol Tablet may decrease the effects of Astriol Tablet.
How to manage the interaction:
Although there is an interaction, Astriol Tablet can be taken with Rifapentine if prescribed by the doctor. The doctor may recommend dose adjustment or special tests to use both medicines safely. Do not discontinue the medication without consulting a doctor.
Taking Astriol Tablet with Fosphenytoin can reduce the levels and efficacy of Astriol Tablet.
How to manage the interaction:
Taking Astriol Tablet with Fosphenytoin together can possibly result in an interaction, but it can be taken if a doctor has advised it. If you notice any symptoms of sudden dizziness, weakness, chest pain or pressure, abnormal body movements, uncontrollable eye movements, itching, burning, or tingling sensation, it's important to contact a doctor right away. Do not stop using any medications without a doctor's advice. Do not discontinue the medication without consulting a doctor.
Drug-Food Interactions
Drug-Food Interactions
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Diet & Lifestyle Advise
- Include dairy products like milk, yoghurt, cheese, or milk-based custard in your diet.
- Eat a serving of broccoli, cabbage, bok choy, spinach, and other green leafy vegetables daily.
- Snack on calcium-rich nuts like Brazil nuts or almonds.
- Sprinkle sesame seeds over your food, vegetables, and salads. Sesame seeds are high in calcium.
- Avoid or reduce the intake of caffeine, soft drinks, and alcohol that inhibit calcium absorption.
- Replace the meat with tofu or tempeh for extra calcium in your food.
Side Effects of Astriol Tablet
- Hypercalcaemia (high calcium levels in the blood)
- Loss of appetite
- Weight loss
- Feeling sick
- Being sick
- Headache and feeling sluggish
- Drowsy or weak
- Stomach pain or discomfort
- Urinary tract infection
- Rash
Habit Forming
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Drug-Diseases Interactions
Drug-Diseases Interactions
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Vitamin D analogues work to raise serum calcium levels and can make arrhythmias worse, especially in people on cardiac glycosides.
How to manage the interaction:
Astriol Tablet increases serum calcium concentrations and may worsen arrhythmia, particularly in patients receiving cardiac glycosides. Astriol Tablet should be administered cautiously in patients with arrhythmia. Monitoring of serum electrolyte concentrations and cardiac function is advised.
The use of vitamin D analogues like calciferol and ergocalciferol in individuals with hypercalcemia, malabsorption syndrome, or signs of vitamin D toxicity is not advised.
How to manage the interaction:
Serum electrolyte concentration should be corrected prior to therapy and monitored during therapy with Astriol Tablet.
Renal biotransformation of ergocalciferol, cholecalciferol, and calcifediol occurs during metabolic activation. Certain vitamin D analogues' therapeutic and metabolic effects may be affected by renal impairment.
How to manage the interaction:
Renal impairment can alter metabolic and therapeutic activity of certain vitamin D analogs. Alternative vitamin D analogs may be considered in patients with compromised renal function.
In order to maintain proper phosphorus levels and prevent ectopic calcification in individuals with renal impairment, vigilance should be exercised because Astriol Tablet increases inorganic phosphate levels in serum.
How to manage the interaction:
Caution is advised in patients with kidney impairment to maintain adequate phosphorus levels and avoid ectopic calcification.
FAQs
Drug-Drug Interactions Checker List
- HYDROCORTISONE
- PREDNISOLONE
- CHOLESTYRAMINE
- DIGOXIN
- DIGITOXIN
- BENDROFLUMETHIAZIDE
- CHLORTALIDONE
- INDAPAMIDE
Special Advise
- Astriol Tablet is not indicated in patients with or with a history of kidney stones, as it may increase the chance of kidney stone formation. Consult your doctor for further advice.
- Your doctor may advise regular monitoring of calcium levels.
Disease/Condition Glossary
Osteoporosis: Osteoporosis is a bone disease that weakens and brittle bones by decreasing bone density. As bones become less dense, they weaken and are more likely to break. Breaking a bone is a serious complication of osteoporosis, especially with older patients. Women are much more likely to develop osteoporosis than are men. Signs and symptoms include back pain caused by a fractured or collapsed vertebra, loss of height over time, a stooped posture, a bone that breaks much more quickly than expected.
Osteomalacia/Rickets: A bone disease caused by softening and weakening bones in children due to inadequate vitamin D. Adults can experience a similar condition known as osteomalacia. It causes bone pain, poor growth, and soft, weak bones that can lead to bone deformities.
Tetany: A disease condition due to low calcium levels (hypocalcemia) in the body causes cramps and spasms in the hands, feet, and larynx (voice box).
Have a query?
Alcohol
Safe if prescribed
Drinking alcohol can affect calcium absorption, hence it is advised to limit the alcohol intake while using Astriol Tablet .
Pregnancy
Consult your doctor
During pregnancy, use higher doses of Astriol Tablet than the daily dietary allowance only when advised by the doctor. Calcitriol in higher doses may harm the fetus. Your doctor will weigh the potential risks and benefits before prescribing Astriol Tablet .
Breast Feeding
Consult your doctor
Consult your doctor before taking Astriol Tablet if you are breastfeeding. Astriol Tablet can pass into the breast milk. If Astriol Tablet is used during breastfeeding, please monitor the mother and the infant's serum calcium levels.
Driving
Safe if prescribed
Astriol Tablet may not affect your ability to drive.
Liver
Consult your doctor
Let your doctor know if you have any history of liver diseases before taking Astriol Tablet . Hepatic impairment/liver disease can alter the metabolic and therapeutic activity of certain Vitamin D forms.
Kidney
Consult your doctor
It is advised to seek doctor advice before starting Astriol Tablet if you have kidney diseases like kidney stones or undergoing dialysis. Calcitriol in Astriol Tablet increases inorganic phosphate levels in serum, hence caution should be taken in patients undergoing dialysis to maintain adequate phosphorus levels and avoid ectopic calcification (calcium deposition).
Children
Safe if prescribed
Astriol Tablet should be used with caution in children and only if prescribed by a doctor.
