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Whats That
About ATZ 50 Tablet
ATZ 50 Tablet belongs to the class of medicine called 'immunosuppressant' that helps to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys. Besides this, it also treats pain and inflammation in gastrointestinal issues like Crohn's disease, and ulcerative colitis, for patients who have undergone a kidney transplant.
ATZ 50 Tablet contains 'Azathioprine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues thereby decreasing pain, inflammation, and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. ATZ 50 Tablet helps stop your body from rejecting a new organ by suppressing your immune system.
Take ATZ 50 Tablet as prescribed. Your doctor will advise you on how often you take ATZ 50 Tablet based on your medical condition. In some cases, you may experience certain common side-effects such as nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, increase in liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.
To treat your condition effectually, continue taking ATZ 50 Tablet for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take ATZ 50 Tablet if you are pregnant or planning for pregnancy. ATZ 50 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. ATZ 50 Tablet should not be given to children as safety and efficacy have not been established. ATZ 50 Tablet may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using ATZ 50 Tablet . While taking ATZ 50 Tablet , do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately as it requires special treatment if you have not had these illnesses. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.
Uses of ATZ 50 Tablet
Directions for Use
Medicinal Benefits
ATZ 50 Tablet contains 'Azathioprine' which is an immunosuppressant that works by reducing the function of the cells, causing inflammation in the joint tissues. It reduces pain, inflammation, and slow joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. ATZ 50 Tablet helps stop your body from rejecting a new organ by suppressing your immune system. ATZ 50 Tablet is also used to treat severe inflammatory diseases of the skin, Crohn's disease and ulcerative colitis, and some blood disorders.
Storage
Drug Warnings
Do not take ATZ 50 Tablet if you are allergic to any immunosuppressant medicines or Azathioprine. Let your doctor know before using ATZ 50 Tablet if you have liver or kidney problems, serious blood disorders, immune system problems, bone marrow problems, serious infections, immunodeficiency syndrome, or if you have a condition where your body produces too little of a natural chemical called thiopurine methyltransferase (TPMT), received any vaccinations. Do not take ATZ 50 Tablet if you are pregnant or planning for pregnancy as ATZ 50 Tablet is a Pregnancy category risk D medicines which can cause serious congenital disabilities to the unborn baby. ATZ 50 Tablet should not be taken by breastfeeding mothers as it passes into breast milk. While taking ATZ 50 Tablet , do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately as it requires special treatment if you have not had these illnesses. ATZ 50 Tablet causes dizziness and drowsiness, so drive with caution. ATZ 50 Tablet should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with ATZ 50 Tablet as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Using ATZ 50 Tablet for a long time can increase your chance of getting certain types of cancer, such as lymphoma (cancer of the spleen, thymus gland, and bone marrow), leukemia (blood cancer), and skin cancer. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using ATZ 50 Tablet .
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ATZ 50 Tablet causes leukopenia (decreased number of white blood cells) and hence may make you more susceptible to infections. Consult your doctor if you develop any signs of infections such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising.
ATZ 50 Tablet acts as an immunosuppressant, which helps in reducing inflammation and prevents joint stiffness, thereby provides relief from rheumatoid arthritis.
If you miss a dose of ATZ 50 Tablet , take the missed dose as soon as you remember it. However, if it's almost time for the next dose, do not take a double dose to make up for a missed one.
Diarrhoea might be a side-effect of ATZ 50 Tablet . Drink lots of fluids and eat food rich in fibre if you experience diarrhoea. If you find blood in stools (tarry stools) or if you experience excess diarrhoea consult your doctor. Do not take anti-diarrheal medicine on your own.
ATZ 50 Tablet is a Category D pregnancy drug that is not recommended for pregnant women or given only when strictly guidance of the doctor as there is no clinical data available on use in pregnant women.
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Special Advise
Disease/Condition Glossary
Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.
Kidney transplant rejection: When you get a new kidney transplanted to your body, your body recognizes it as a foreign element and tries to attack, and reject it because it is not originally part of your body. So, immunosuppressant drugs like Azathioprine are given to such patients to suppress your immune system to attack a newly transplanted kidney. The ultimate goal is to adjust immunosuppressant to prevent rejection and to minimize any side effects of the drugs.
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