ATZ 50 Tablet 10's

ATZ 50 Tablet 10's belongs to the class of medicine called 'immunosuppressant' that helps to reduce the pain/inflammation in rheumatoid arthritis conditions and keep the immune system from attacking new transplant organs like kidneys. Besides this, it also treats pain and inflammation in gastrointestinal issues like Crohn's disease, and ulcerative colitis, for patients who have undergone a kidney transplant. 

ATZ 50 Tablet 10's contains 'Azathioprine' that works by reducing the function of the cells, causing inflammation, especially in the joint tissues thereby decreasing pain, inflammation, and slowing down the joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. ATZ 50 Tablet 10's helps stop your body from rejecting a new organ by suppressing your immune system. 

Take ATZ 50 Tablet 10's as prescribed. Your doctor will advise you on how often you take ATZ 50 Tablet 10's based on your medical condition. In some cases, you may experience certain common side-effects such as nausea, headaches, vomiting, diarrhoea, unusual fatigue, dizziness, headache, loss of appetite, increase in liver enzymes, lowered resistance to infections, tingling sensation, stomach pain, leukopenia (decreased number of white blood cells), and sore throat. Most of these side effects do not require medical attention and will resolve gradually over time. However, you are advised to talk to your doctor if you experience these side effects persistently.

To treat your condition effectually, continue taking ATZ 50 Tablet 10's for as long as your doctor has prescribed. To avoid recurring symptoms, do not stop it midway. Do not take ATZ 50 Tablet 10's if you are pregnant or planning for pregnancy. ATZ 50 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. ATZ 50 Tablet 10's should not be given to children as safety and efficacy have not been established. ATZ 50 Tablet 10's may make you more susceptible to infections; consult your doctor if you develop any signs of severe conditions such as fever, sore throat, breathlessness, jaundice, unexplained bleeding, or bruising. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using ATZ 50 Tablet 10's. While taking ATZ 50 Tablet 10's, do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately as it requires special treatment if you have not had these illnesses. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Inform your doctor about your health condition and medicines to rule out any unpleasant side effects.

ATZ 50 Tablet 10's contains 'Azathioprine' which is an immunosuppressant that works by reducing the function of the cells, causing inflammation in the joint tissues. It reduces pain, inflammation, and slow joint damage and disease progression over time. Besides this, after an organ transplant, your body will try to attack the new organ as it sees it as foreign. ATZ 50 Tablet 10's helps stop your body from rejecting a new organ by suppressing your immune system. ATZ 50 Tablet 10's is also used to treat severe inflammatory diseases of the skin, Crohn's disease and ulcerative colitis, and some blood disorders.

• Nausea
• Headaches
• Vomiting
• Diarrhoea
• Unusual fatigue
• Dizziness
• Headache
• Loss of appetite
• Increase in liver enzymes
• Lowered resistance to infections
• Tingling sensation
• Stomach pain
• Leukopenia (decreased number of white blood cells)
• Sore throat

Do not take ATZ 50 Tablet 10's if you are allergic to any immunosuppressant medicines or Azathioprine. Let your doctor know before using ATZ 50 Tablet 10's if you have liver or kidney problems, serious blood disorders, immune system problems, bone marrow problems, serious infections, immunodeficiency syndrome, or if you have a condition where your body produces too little of a natural chemical called thiopurine methyltransferase (TPMT), received any vaccinations. Do not take ATZ 50 Tablet 10's if you are pregnant or planning for pregnancy as ATZ 50 Tablet 10's is a Pregnancy category risk D medicines which can cause serious congenital disabilities to the unborn baby. ATZ 50 Tablet 10's should not be taken by breastfeeding mothers as it passes into breast milk. While taking ATZ 50 Tablet 10's, do not contact anyone who has shingles, chickenpox, or measles. If you accidentally come in contact with any person having them, please inform your doctor immediately as it requires special treatment if you have not had these illnesses. ATZ 50 Tablet 10's causes dizziness and drowsiness, so drive with caution. ATZ 50 Tablet 10's should not be given to children as safety and efficacy have not been established. Avoid consuming alcohol along with ATZ 50 Tablet 10's as it could lead to increased dizziness. Your doctor may advise you to undergo regular blood tests, kidney and liver tests to monitor your condition. Using ATZ 50 Tablet 10's for a long time can increase your chance of getting certain types of cancer, such as lymphoma (cancer of the spleen, thymus gland, and bone marrow), leukemia (blood cancer), and skin cancer. Avoid excessive exposure to sunlight, wear protective clothing, and use protective sunscreen with a high protection factor while using ATZ 50 Tablet 10's.

Drug-Drug Interaction: ATZ 50 Tablet 10's may have interaction with other immunosuppressant medicines (tacrolimus), anti-gout (allopurinol, oxypurinol, thiopurine), angiotensin-converting enzyme (ACE) inhibitors (benazepril, captopril, enalapril, fosinopril, moexipril, perindopril, quinapril, ramipril), blood thinner (warfarin, phenprocoumon), medicines used to treat inflammation of the bowels (infliximab), medicines used to treat ulcers (cimetidine, olsalazine, mesalazine, sulfasalazine), diuretics (furosemide), medicines used to treat bacterial infections (trimethoprim, sulfamethoxazole), pain killers (indomethacin), medicines used as muscle relaxants (d-tubocurarine, pancuronium, succinylcholine).

Drug-Food Interaction:  Avoid alcohol consumption while taking ATZ 50 Tablet 10's as it may increase dizziness.

Drug-Disease Interaction: ATZ 50 Tablet 10's may cause interactions with disease conditions such as leukopenia (low levels of white blood cells), infections, have any unusual bleeding or bruising liver, and kidney dysfunction.

• TACROLIMUS
• ALLOPURINOL
• BENAZEPRIL
• CAPTOPRIL
• ENALAPRIL
• FOSINOPRIL
• LISINOPRIL
• PERINDOPRIL
• RAMIPRIL
• WARFARIN
• PHENPROCOUMON
• INFLIXIMAB
• CIMETIDINE
• MESALAZINE
• SULFASALAZINE
• FUROSEMIDE
• TRIMETHOPRIM+SULFAMETHOXAZOLE
• INDOMETHACIN
• TUBOCURARINE
• PANCURONIUM
• SUCCINYLCHOLINE

• Use sunscreen while taking ATZ 50 Tablet 10's, as it can make your skin more sensitive to sunlight and may cause skin cancer.
• Long-term use of ATZ 50 Tablet 10's may increase your risk of developing cancers like blood cancer, skin cancer and immune system cancer (lymphoma). 

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue) that leads to joint pain and damage. Symptoms of rheumatoid arthritis include pain, inflammation of joints, difficulty moving, and swelling.

Kidney transplant rejection: When you get a new kidney transplanted to your body, your body recognizes it as a foreign element and tries to attack, and reject it because it is not originally part of your body. So, immunosuppressant drugs like Azathioprine are given to such patients to suppress your immune system to attack a newly transplanted kidney. The ultimate goal is to adjust immunosuppressant to prevent rejection and to minimize any side effects of the drugs.