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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Composition :

TRETINOIN-0.025%W/W

Manufacturer/Marketer :

Aviator Life Science Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About Avitra Gel

Avitra Gel belongs to a class of drugs called retinoids (similar to vitamin A). Avitra Gel is used to treat acute promyelocytic leukaemia (a type of blood problem). Acute promyelocytic leukaemia is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. 

Avitra Gel contains Tretinoin, a form of vitamin A that works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

Take Avitra Gel as prescribed. Your doctor will advise you how often you need to take Avitra Gel based on your medical condition. Some people may experience dizziness, headache, feeling tired, stomach pain, irregular heartbeat, hair loss, bone or joint pain, dry skin and changes in eyesight or hearing. Most of these side effects of Avitra Gel do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor. 

If you are allergic to Tretinoin, peanuts, soya or any other ingredients in Avitra Gel, please tell your doctor. Avoid taking Avitra Gel if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Avitra Gel as it is excreted into breast milk and may harm the baby. Avoid taking Avitra Gel if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Avitra Gel as it may contain sorbitol.

Uses of Avitra Gel

Acute promyelocytic leukaemia

Directions for Use

Take Avitra Gel preferably with a meal or as advised by the doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Avitra Gel is a form of vitamin A that is primarily used to treat acute promyelocytic leukaemia (a type of blood problem). Avitra Gel reduces the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.  

Storage

Store in a cool and dry place away from sunlight

Side Effects of Avitra Gel

  • Dizziness
  • Headache
  • Feeling tired
  • Stomach pain
  • Irregular heartbeat
  • Hair loss
  • Bone or joint pain
  • Dry skin
  • Changes in eyesight or hearing

Drug Warnings

If you are allergic to Tretinoin, peanuts, soya or any other ingredients, please tell your doctor. Avoid taking Avitra Gel if you are pregnant as it may harm the foetus. Avoid breastfeeding while taking Avitra Gel as it is excreted into breast milk and may harm the baby. You are advised to use effective contraceptive methods while using Avitra Gel to prevent pregnancy. Avoid taking Avitra Gel if you are taking other retinoid medicines (acitretin, tazarotene, isotretinoin), vitamin A and tetracyclines (antibiotics). If you are allergic to any sugars, please inform your doctor before taking Avitra Gel as it may contain sorbitol.

Diet & Lifestyle Advise

  • Eat 5 portions of vegetables and fruits in a day.
  • Reduce the intake of salt and fat.
  • Regular exercise may help to reduce depression and excessive tiredness after treatment.
  • Start with gentle walking and once your white blood cell count comes back to normal, you can go swimming.
  • Avoid alcohol consumption.

Habit Forming

No

Therapeutic Class

RETINOIDS

Avitra Gel Substitute

Substitutes safety advice
  • Tretin 0.025% Cream 30 gm

    by Others

    6.03per tablet
  • Revize Micro 0.025% Gel 20 gm

    by Others

    12.23per tablet
  • A-Ret 0.025% Gel 20 gm

    by Others

    5.67per tablet
  • Nioret Nano Gel 15 gm

    by Others

    20.46per tablet
  • Mytret 0.025% Gel 15 gm

    by Others

    8.40per tablet

Author Details

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FAQs

Avitra Gel works by reducing the excessive production of abnormal blood cells and stimulates the growth of normal, mature cells in blood and bone marrow. Thus, helps in the treatment of acute promyelocytic leukaemia.

You are recommended to avoid pregnancy while taking Avitra Gel and for 1 month after stopping treatment with Avitra Gel as it may cause the birth of the deformed baby. Therefore, you are advised to use effective contraceptive measures while taking Avitra Gel and for 1 month after stopping treatment with Avitra Gel to prevent pregnancy. Also, women using Avitra Gel should take a pregnancy test every month and if you become pregnant while taking Avitra Gel, inform your doctor immediately.

Avitra Gel may cause dizziness as a temporary side effect. Therefore, drive only if you are alert after taking Avitra Gel.

You are not recommended to take low-dose progestogens (mini pill) with Avitra Gel as their effectiveness may be reduced. However, discuss with your doctor if you have any concerns regarding this so that a different oral contraceptive may be prescribed.

Avitra Gel may cause painful swelling in the leg in a few patients. If you experience painful swelling in your leg, difficulty breathing or sudden chest pain while taking Avitra Gel, please inform your doctor immediately as these might be signs of a blood clot.

Drug-Drug Interactions Checker List

  • ERYTHROMYCIN
  • CLARITHROMYCIN
  • RIFAMPICIN
  • TETRACYCLINE
  • VITAMIN A
  • KETOCONAZOLE
  • ITRACONAZOLE
  • POSACONAZOLE
  • FLUCONAZOLE
  • DEXAMETHASONE
  • PREDNISOLONE
  • PHENOBARBITAL
  • SAQUINAVIR
  • RITONAVIR
  • DILTIAZEM
  • VERAPAMIL
  • CIMETIDINE
  • CICLOSPORIN
  • APROTININ
  • AMINOCAPROIC ACID
  • TRANEXAMIC ACID

Special Advise

Avitra Gel may affect your mood and behaviour. Therefore, you are recommended to inform your family and friends that you are taking Avitra Gel so that they may notice any changes and help you identify problems that are needed to be discussed with your doctor.

Disease/Condition Glossary

Acute promyelocytic leukaemia (APL): It is a blood cancer that causes a marked increase in a type of immature white blood cells known as promyelocytes in the blood and bone marrow. The symptoms of APL include blood in the urine, nosebleeds, loss of appetite, extreme tiredness, unexplained bruising or excessive bleeding from small cuts.

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