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Written By Divya L , PharmaD
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Cadila Healthcare Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

About AXEMAL TABLET

AXEMAL TABLET belongs to the class of 'anti-inflammatory drugs.' It has various medical uses, including treatment for type 2 diabetes mellitus, acute or chronic rheumatoid arthritis, dyslipidaemia (abnormally elevated cholesterol levels), systemic and discoid lupus erythematosus (autoimmune disease), polymorphous light eruption (a rash caused by sun exposure), and malaria. 

AXEMAL TABLET contains Hydroxychloroquine, an anti-inflammatory drug. For diabetes, it works by improving insulin sensitivity and increasing insulin secretion. In rheumatoid arthritis, Hydroxychloroquine acts as a mild immunosuppressant and disease-modifying anti-rheumatic agent and inhibits the production of rheumatoid factor. It also decreases the severity of skin lesions in systemic and discoid lupus erythematosus. In malaria, it works by increasing the concentration of a toxic compound in the parasite that leads to its death.

Take this medicine as prescribed by a doctor. AXEMAL TABLET may cause common side effects like blurred vision, abdominal pain, nausea, vomiting, loss of appetite, diarrhoea, headache, mood changes, skin rashes, itching, sensitivity to light, and pigmentation disorders. These side effects are not familiar to everyone and may vary individually. If you notice any side effects that are not manageable, please consult your doctor. 

Before taking AXEMAL TABLET, please inform your doctor if you are allergic to medicines, liver/kidney/heart diseases, gastrointestinal problems, blood disorders, and brain-related problems. Pregnant and breastfeeding women should consult their doctor before starting AXEMAL TABLET. AXEMAL TABLET may cause blurred vision; hence do not drive or operate machinery until you feel better. The safety and efficacy of AXEMAL TABLET have not been established in children; please seek medical advice for more information.

Uses of AXEMAL TABLET

Type 2 diabetes mellitus, acute or chronic rheumatoid arthritis, dyslipidaemia, systemic and discoid lupus erythematosus, polymorphous light eruption, and malaria.

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Hydroxychloroquine has diversified medical uses and works by reducing inflammation in people with autoimmune diseases. It helps treat type 2 diabetes mellitus and autoimmune conditions like rheumatoid arthritis, systemic lupus erythematosus, and malaria. For diabetes, it works by improving insulin sensitivity and increasing insulin secretion. In rheumatoid arthritis, Hydroxychloroquine acts as a mild immunosuppressant and disease-modifying anti-rheumatic agent and inhibits the production of rheumatoid factor. In malaria, it works by increasing the concentration of a toxic compound in the parasite that leads to its death. Hydroxychloroquine is an anti-thrombotic and anti-platelet agent that helps reduce abnormally elevated cholesterol levels. It also decreases the severity of skin lesions in systemic and discoid lupus erythematosus.

Storage

Store in a cool and dry place away from sunlight

Side Effects of AXEMAL TABLET

  • Blurred vision
  • Abdominal pain
  • Nausea
  • Vomiting
  • Loss of appetite
  • Diarrhoea
  • Headache
  • Mood changes
  • Skin rashes
  • Itching
  • Sensitivity to light
  • Pigmentation disorders

Drug Warnings

Before using AXEMAL TABLET, inform your doctor if you have recently used any prescription and non-prescription medications. Keep your doctor informed of your medical history before starting AXEMAL TABLET. Please seek medical advice if you are pregnant or breastfeeding before taking AXEMAL TABLET. This medicine may cause blurred vision; hence drive or operate machinery only when you are alert and have clear vision. Avoid alcohol consumption while being treated with AXEMAL TABLET. Safety and efficacy of AXEMAL TABLET have not been established in children.

Drug-Drug Interactions

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HydroxychloroquineCisapride
Critical
HydroxychloroquineAurothioglucose
Critical

Drug-Drug Interactions

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HydroxychloroquineCisapride
Critical
How does the drug interact with Axemal Tablet:
Combining Cisapride and Haloperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Cisapride and Haloperidol together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
HydroxychloroquineAurothioglucose
Critical
How does the drug interact with Axemal Tablet:
Using Aurothioglucose and Axemal Tablet together can cause blood disorders and other severe side effects.

How to manage the interaction:
Taking Axemal Tablet with Aurothioglucose is not recommended, please consult your doctor before taking it. If you experience any symptoms, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
HydroxychloroquineZiprasidone
Critical
How does the drug interact with Axemal Tablet:
Taking Ziprasidone and Haloperidol can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Ziprasidone and Haloperidol together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, heart palpitations, diarrhea, or vomiting, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
HydroxychloroquineSolifenacin
Severe
How does the drug interact with Axemal Tablet:
The combined use of solifenacin and Axemal Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of solifenacin and Axemal Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxychloroquineRisperidone
Severe
How does the drug interact with Axemal Tablet:
Coadministration of risperidone and Axemal Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of risperidone and Axemal Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxychloroquineLenvatinib
Severe
How does the drug interact with Axemal Tablet:
Coadministration of Lenvatinib and Axemal Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Lenvatinib and Axemal Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxychloroquineImipramine
Severe
How does the drug interact with Axemal Tablet:
The combined use of imipramine and Axemal Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of imipramine and Axemal Tablet can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult the doctor immediately. Do not stop using any medications without a doctor's advice.
HydroxychloroquineTramadol
Severe
How does the drug interact with Axemal Tablet:
The combined use of tramadol with Axemal Tablet can make tramadol less effective as a treatment.

How to manage the interaction:
Taking Axemal Tablet with tramadol together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience any symptoms such as confusion, hallucination, seizure, increased heart rate, blurred vision, tremors, incoordination, stomach cramps, nausea, vomiting, and diarrhea, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
HydroxychloroquineChlorpromazine
Severe
How does the drug interact with Axemal Tablet:
Using Axemal Tablet together with chlorpromazine can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking chlorpromazine and Axemal Tablet together can possibly result in an interaction, it can be taken if your doctor has advised it. However, if you experience sudden dizziness, lightheadedness, fainting, shortness of breath, or rapid heartbeat, contact your doctor. Do not discontinue any medications without first consulting your doctor.
HydroxychloroquineClarithromycin
Severe
How does the drug interact with Axemal Tablet:
Taking clarithromycin with Axemal Tablet can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Although there is a possible interaction, clarithromycin can be taken with daclatasvir if prescribed by the doctor. Consult the prescriber immediately if you experience sudden lightheadedness, dizziness, fainting, shortness of breath, or heart palpitations during treatment with these medications. Do not discontinue the medication without consulting a doctor.

Drug-Food Interactions

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HYDROXYCHLOROQUINE-200MGGrapefruit and Grapefruit Juice
Moderate

Drug-Food Interactions

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HYDROXYCHLOROQUINE-200MGGrapefruit and Grapefruit Juice
Moderate
Common Foods to Avoid:
Grapefruit Juice, Grapefruit

How to manage the interaction:
Grapefruit juice can increase the blood levels and effects of Axemal Tablet, which may result in an irregular heart rate or other conduction disturbances. consumption of grape juice or grapefruit can lead to an interaction. However, if you experience any symptoms like sudden dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult doctor immediately. avoid grape fruit.

Diet & Lifestyle Advise

  • Maintain a fibre-rich diet and include fruits, vegetables and whole grains to maintain your blood glucose levels.
  • Eat at regular intervals.
  • Keep a check on your weight and exercise regularly to keep your heart healthy.
  • Notice and manage the early symptoms of high/low blood sugar levels.
  • During malarial fever, the patient may experience appetite loss. In such cases, drink glucose water, fresh fruit juices, and coconut water.
  • Include high-fibre foods like green leafy vegetables and fruits to aid digestion.
  • Avoid or limit the intake of alcohol and caffeine.

Habit Forming

No

Therapeutic Class

ANTIDIABETICS

AXEMAL TABLET Substitute

Substitutes safety advice
  • HCQS 200 Tablet 15's

    by Others

    7.10per tablet
  • HCQS-200 Tablet 10's

    by AYUR

    6.39per tablet
  • Zy-Q 200 Tablet 30's

    by Others

    6.29per tablet
  • Cartiquin 200 mg Tablet 15's

    by AYUR

    6.39per tablet
  • Hqtor 200 mg Tablet 10's

    by Others

    6.39per tablet

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

AXEMAL TABLET contains Hydroxychloroquine, an anti-inflammatory drug that reduces inflammation in people with autoimmune disorders. Hydroxychloroquine improves insulin sensitivity in diabetes and has a hypoglycaemic effect. It is a disease-modifying anti-rheumatic agent that inhibits the production of rheumatoid factor in rheumatoid arthritis. It also decreases the elevated cholesterol levels in the body and reduces the risk of cardiovascular diseases. Hydroxychloroquine is also an anti-malarial drug that treats malaria by increasing the concentration of a toxic compound in the parasite that leads to its death.

Inform your doctor in advance if you have any liver or kidney problems, heart diseases, diabetes, G-6-PD (glucose-6 phosphate dehydrogenase) deficiency (a genetic enzyme deficiency), high blood pressure, serious stomach or gut problems, nervous system problems, psoriasis, porphyria (a blood disorder), history of heart attack (myocardial infarction), electrolyte imbalance, fits, and allergic reactions to medicines.

AXEMAL TABLET may cause drug-induced retinopathy (disease related to the retina) when taken more than recommended. You may not be advised AXEMAL TABLET by your doctor if you have vision changes or damage to your retina. If the doctor has prescribed you this medicine knowing your medical history, you may be further advised to take ophthalmological examinations, including visual acuity, ophthalmoscopy, fundoscopy, and visual field tests. If there are any changes in these examinations, you may be asked to discontinue the treatment.

Hydroxychloroquine may sometimes affect mental health and cause problems like irrational thoughts, anxiety, hallucinations, feeling confused or feeling depressed, including thoughts of self-harm or suicide. Hence, you should speak to your doctor before using AXEMAL TABLET.

Drug-Drug Interactions Checker List

  • TAMOXIFEN
  • DIGOXIN
  • AMIODARONE
  • HALOFANTRINE
  • MEFLOQUINE
  • MOXIFLOXACIN
  • AZITHROMYCIN
  • PENICILLAMINE
  • CICLOSPORIN
  • CIMETIDINE
  • AMISULPRIDE
  • QUETIAPINE
  • INSULIN HUMAN

Special Advise

  • Let your doctor/laboratory staff know that you are taking AXEMAL TABLET if you undergo medical tests.
  • While being treated with AXEMAL TABLET, your doctor may suggest ECG (electrocardiogram) to monitor your heart health.
  • Your doctor may also suggest tests for blood cell counts (during prolonged therapy) and liver and kidney function tests.

Disease/Condition Glossary

Diabetes mellitus: It is also known as adult-onset diabetes, is a metabolic disease that causes high blood sugar levels. It occurs when the insulin (a hormone produced by the beta cells of the pancreas) is resistant in breaking the glucose to produce energy (insulin resistance), or the pancreas (an organ behind the stomach) produces little or no insulin at all. This disease mostly occurs in people above 40 years but can also occur in childhood based on the risk factors. 

Malaria: It is a life-threatening disease caused by parasites that enter the body through a mosquito's bite. This disease usually occurs when an Anopheles mosquito (infected with the parasite 'Plasmodium') bites a healthy individual and transfers the parasite into the bloodstream. Symptoms include chills, high fever, profuse sweating, headache, nausea, vomiting, abdominal pain, diarrhoea, anaemia, muscle pain, convulsions, coma, and bloody stools.

Rheumatoid arthritis: It is an autoimmune disease (the body's immune system attacks its tissue), leading to joint pain and damage. Symptoms of rheumatoid arthritis include pain, swelling, stiffness, deformities, and loss of joint function. 

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