Axicralf 1000mg Suspension belongs to a gastrointestinal class of drugs called 'ulcer protectants' primarily used to prevent or treat peptic ulcers or gastrointestinal ulcers. A peptic ulcer is a sore on the stomach's lining or the first part of the small intestine (duodenum). Ulcer or sores of the stomach region is called gastric ulcer, while ulcer of the duodenum is known as duodenal ulcer.

Axicralf 1000mg Suspension contains 'Sucralfate', which works by forming a protective barrier or coat over the ulcer so that digestive enzymes, acid and bile salts cannot further irritate the lining of the stomach and duodenum. This protects the ulcer from the stomach's acid, allowing it to heal.

Your doctor will advise you on how often you take Axicralf 1000mg Suspension based on your medical condition. Some people may experience common side effects like constipation, dizziness, sleepiness, dry mouth, blurred vision, and diarrhoea. Most of these side effects of Axicralf 1000mg Suspension do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

Avoid taking any antacid like magnesium hydroxide or aluminium hydroxide within 30 minutes before or after taking Axicralf 1000mg Suspension. If you are known to be allergic to Axicralf 1000mg Suspension or active and inactive ingredients present on it, please tell your doctor. If you are pregnant or breastfeeding, it is advised to consult a doctor before using Axicralf 1000mg Suspension. Duodenal ulcer tends to be a recurrent disease. Try not to stop taking Axicralf 1000mg Suspension of your own. Stopping a sudden intake of Axicralf 1000mg Suspension will not influence the frequency or severity of future ulceration. Let your doctor know if you have any kidney problems. People with reduced kidney function may be more likely to experience side effects of aluminium accumulation with Axicralf 1000mg Suspension. The dose adjustment is necessary for patients with kidney disease and elderly patients.

Axicralf 1000mg Suspension is a class of an anti-ulcer drugs prescribed for treating or preventing the return of duodenal ulcers (ulcers located in the first part of the small intestines). Axicralf 1000mg Suspension works by forming a protective barrier or coat over the ulcer to pepsin and bile and inhibits the diffusion of gastric acid. This protects the ulcer from the stomach's acid, allowing it to heal. Axicralf 1000mg Suspension exhibits a cytoprotective effect and forms a viscous, adhesive barrier on the surface of the intact intestinal mucosa and the stomach. Axicralf 1000mg Suspension stimulates the synthesis and release of gastric mucosal prostaglandins, bicarbonate, and the epidermal growth factor, which promotes healing.

• Constipation
• Dizziness
• Sleepiness
• Dry mouth
• Nausea

You should avoid taking Axicralf 1000mg Suspension if you are allergic to Axicralf 1000mg Suspension or other ingredients present in it, have kidney disease, stomach/intestine problems (delayed gastric emptying), are pregnant or planning for pregnancy, and are a breastfeeding mother. Caution is required before giving Axicralf 1000mg Suspension to elderly patients. Axicralf 1000mg Suspension contains aluminium, which is normally removed by your kidney. Therefore, older adults and people with kidney problems may be at greater risk for developing high aluminium levels while using this drug with other products containing aluminium (e.g. antacids). The safety and effectiveness in children are not established; please consult your doctor before giving Axicralf 1000mg Suspension to children.

Drug-Drug Interactions: Axicralf 1000mg Suspension interacts with the anti-HIV drug (dolutegravir), vitamin D analogues (doxercalciferol, paricalcitol), antibiotic (ciprofloxacin, gemifloxacin, levofloxacin), antidiabetic (acarbose, metformin, glipizide, glimepiride, glyburide), antacid drug (magaldrate, aluminium hydroxide) blood thinner (warfarin).

Drug-Food Interactions: Drinking alcohol and nicotine (tobacco) with Axicralf 1000mg Suspension may cause dehydration and elevate the level of stomach acid, thereby decreasing Axicralf 1000mg Suspension efficacy.

Drug-Disease Interactions: Before taking Axicralf 1000mg Suspension, inform your doctor if you have any kidney or liver disease as a dose of Axicralf 1000mg Suspension needs to be adjusted.

• DOLUTEGRAVIR
• DOXERCALCIFEROL
• PARICALCITOL
• CIPROFLOXACIN
• GEMIFLOXACIN
• LEVOFLOXACIN
• ACARBOSE
• METFORMIN
• GLIPIZIDE
• ALUMINUM HYDROXIDE
• WARFARIN

• Avoid intake of acid or heartburn triggering foods or drinks like peppermint, chocolate, onions, caffeinated beverages, citrus fruits or juices, tomatoes, and high-fat and spicy foods.
• Eating five or six smaller meals throughout the day rather than three large meals. It can help reduce the production of stomach acid.
• Avoid taking alcohol and smoking cigarettes and red meat. It increases the production of stomach acid and makes symptoms worse. It can also cause erosion of the stomach lining.
• Include the high fiber-containing foods, leafy green veggies (kale, spinach), green tea in your meal. Fermented dairy products like miso, sauerkraut, and kimchi contain probiotics which help in the prevention of excess acid production.
• Cranberry juice can be beneficial in peptic ulcers and H. pylori infections.

Axicralf 1000mg Suspension is prescribed for acute or short-term conditions of duodenal ulcer. Do not take Axicralf 1000mg Suspension for more than eight weeks. If still, your duodenal ulcer persists, stop taking Axicralf 1000mg Suspension and contact a doctor. Axicralf 1000mg Suspension contains aluminium, so if you are a kidney patient, let your doctor know about this before taking Axicralf 1000mg Suspension.

Duodenal ulcer: It is a sore that forms in the lining of the small intestine just beyond the stomach (duodenum). The stomach makes a strong acid that kills germs and helps you digest food. To protect themselves against this acid, duodenum cells make a barrier from mucus. If this barrier is damaged, an ulcer can form. The main cause of this barrier damage is infection with bacteria (H. pylori), medicines like NSAIDs or painkillers (aspirin, ibuprofen). If you have a duodenum ulcer, you might have symptoms like have pain in the stomach or abdomen (this might come and go and is relieved by taking an antacid), indigestion, nauseous, feeling full after taking a small amount of food, bloody or black stools.