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Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy
Non returnable*
COD available

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Whats That

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Composition :

TEMOZOLOMIDE-20MG

Manufacturer/Marketer :

Axiommax Oncology Pvt Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Axiotem 20 mg Capsules

Axiotem 20 mg Capsules belongs to a class of medicines called 'anti-cancer/ antitumor agent', used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. A brain tumour is an uncontrolled and unregulated proliferation of cells in the brain. 

Axiotem 20 mg Capsules contains Temozolomide which works by inhibiting the production of DNA (deoxyribonucleic acid-genetic material of the cell), thereby affecting cell growth and division. Thus, Axiotem 20 mg Capsules prevents tumours from growing.

Take Axiotem 20 mg Capsules as prescribed. In some cases, Axiotem 20 mg Capsules may cause loss of appetite, anxiety, confusion, headache, vomiting, nausea, diarrhoea, constipation, muscle weakness, muscle aches, and fever. Most of these side effects of Axiotem 20 mg Capsules do not require medical attention and gradually resolve over time. However, if the side effects are persistent, reach out to your doctor.

Let your doctor know if you are allergic to any of the contents. Axiotem 20 mg Capsules is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Axiotem 20 mg Capsules if you are pregnant or breastfeeding. Both women and men using Axiotem 20 mg Capsules should use birth control to avoid pregnancy and fathering a child. It would be best not to drive and/or operate machines that require alertness as Axiotem 20 mg Capsules may cause tiredness or sleepiness.

Uses of Axiotem 20 mg Capsules

Brain tumour

Directions for Use

Swallow it as a whole with water; do not crush, break or chew it.

Medicinal Benefits

Axiotem 20 mg Capsules belongs to a class of medicines called anti-cancer/antitumor agents used to treat specific forms of brain tumours such as glioblastoma multiforme (a type of tumour that grows and spreads rapidly) in adults and malignant glioma, including glioblastoma multiforme or anaplastic astrocytoma (a rare malignant brain tumour) in patients older than 3years. It contains Temozolomide which works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Axiotem 20 mg Capsules prevents tumours from growing.

Storage

Store in a cool and dry place away from sunlight
Side effects of Axiotem 20 mg Capsules
  • Eat protein-rich foods like fish, poultry, eggs, and legumes.
  • Include foods with minerals and vitamins essential for hair health.
  • Join a support group to connect with others experiencing hair loss.
  • Openly discuss your feelings about hair loss.
  • Consider covering up with wigs, hats, or scarves.
  • Be patient and avoid seeking miracle cures.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Rest well; get enough sleep.
  • Eat a balanced diet and drink enough water.
  • Manage stress with yoga and meditation.
  • Limit alcohol and caffeine.
  • Physical activities like walking or jogging might help boost energy and make you feel less tired.
  • Wear compression garments like stockings, sleeves, or gloves to apply pressure and help stop fluid from building up, especially after the swelling goes down.
  • Move around and do exercises to help the fluid circulate, especially in swollen limbs. Ask your doctor for specific exercises.
  • Raise the swollen area above your heart level several times a day, even while sleeping, to help reduce swelling.
  • Gently massage the swollen area with firm but not painful pressure.
  • Keep the swollen area clean and moisturized to prevent injury and infection.
  • Reduce salt intake to help prevent fluid from building up and worsening the swelling, as advised by a doctor.
  • If the swelling does not get better after a few days of home treatment or worsens, consult your doctor right away.
  • Managing a low platelet count (thrombocytopenia) caused by medication usage requires a multi-step approach. Here are some steps to help manage the condition:
  • Inform your doctor about your low platelet count and medication usage. They will assess the situation and guide the best course of action.
  • Your doctor may recommend adjusting or stopping the medication that is causing a low platelet count. This could involve switching to alternative medication or reducing the dosage.
  • Monitor your platelet count regularly through blood tests to track any changes. This will help the doctor determine the effectiveness of the treatment plan.
  • If an underlying condition, such as infection or inflammation, contributes to the low platelet count, your doctor will treat it.
  • In some cases, alternative treatments like platelet transfusions or medications that stimulate platelet production may be necessary.
  • Avoid risky activities and certain medications; eat a balanced diet with plenty of water to reduce bleeding risk and boost overall health.
  • If you experience severe bleeding or bruising, seek emergency medical attention immediately.
Dealing with Medication-Induced Headache:
  • Hydrate your body: Drink enough water to prevent dehydration and headaches.
  • Calm Your Mind: Deep breathing and meditation can help you relax and relieve stress.
  • Rest and Recharge: Sleep for 7-8 hours to reduce headache triggers.
  • Take rest: lie down in a quiet, dark environment.
  • Cold or warm compresses can help reduce tension.
  • Stay Upright: Maintain good posture to keep symptoms from getting worse.
  • To treat headaches naturally, try acupuncture or massage therapy.
  • Over-the-counter pain relievers include acetaminophen and ibuprofen.
  • Prescription Assistance: Speak with your doctor about more substantial drug alternatives.
  • Severe Headaches: Seek emergency medical assistance for sudden, severe headaches.
  • Frequent Headaches: If you get reoccurring headaches, consult your doctor.
  • Headaches with Symptoms: Seek medical attention if your headaches include fever, disorientation, or weakness.

Drug Warnings

Axiotem 20 mg Capsules should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Axiotem 20 mg Capsules. To treat your condition effectually, continue taking Axiotem 20 mg Capsules for as long as your doctor has prescribed. Do not stop Axiotem 20 mg Capsules midway under any circumstances without consulting the healthcare professional. Inform your doctor if you have an allergy to any components of Axiotem 20 mg Capsules. Inform your doctor before taking Axiotem 20 mg Capsules if you have allergic reactions, infections, lung, renal or hepatic disorders or low blood count (including neutropenia, lymphopenia, thrombocytopenia). Axiotem 20 mg Capsules is not recommended for patients with severe bone marrow depression or significant bleeding. Avoid taking Axiotem 20 mg Capsules if you are pregnant or breastfeeding. Both women and men using Axiotem 20 mg Capsules should use birth control to avoid pregnancy or fathering a child. Do not receive any vaccinations or immunizations without your doctor's approval while taking Axiotem 20 mg Capsules.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Axiotem 20 mg Capsules:
Taking thalidomide with Axiotem 20 mg Capsules can increase the risk of blood clots.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and thalidomide together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, and/or pain, redness or swelling in an arm or leg. Do not stop using any medications without consulting doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Taking Axiotem 20 mg Capsules with Leflunomide can increase the risk of infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and leflunomide together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, pain or burning during urination, vomiting, dark-colored urine, light-colored stools, and/or yellowing of the skin or eyes. Do not stop using any medications without consulting a doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Taking Axiotem 20 mg Capsules with Fingolimod can increase the risk of infection.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and fingolimod together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
TemozolomideVoclosporin
Severe
How does the drug interact with Axiotem 20 mg Capsules:
Taking voclosporin with Axiotem 20 mg Capsules, may increase the risk of serious infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and voclosporin together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Taking Axiotem 20 mg Capsules with Etanercept can increase the risk of infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and etanercept together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Taking Axiotem 20 mg Capsules with clozapine may increase the risk of serious infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and clozapine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Taking baricitinib and Axiotem 20 mg Capsules can increase the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Axiotem 20 mg Capsules if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in your coughing fluid, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not stop using any medications without talking to a doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Taking Axiotem 20 mg Capsules with Infliximab can increase the risk of infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and infliximab together can result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting a doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Using adalimumab together with Axiotem 20 mg Capsules may increase the risk of serious infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and adalimumab together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.
How does the drug interact with Axiotem 20 mg Capsules:
Using cladribine together with Axiotem 20 mg Capsules may increase the risk of serious infections.

How to manage the interaction:
Although taking Axiotem 20 mg Capsules and cladribine together can possibly result in an interaction, it can be taken if your doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, red or inflamed skin, body sores, and pain or burning during urination. Do not stop using any medications without consulting doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • De-stress yourself by meditating, reading books, taking a warm bubble bath or listening to soothing music.
  • Performing yoga may also help in improving both physical and mental health.
  • Maintain a healthy weight by performing regular low-strain exercises and eating healthy food.
  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Include leafy vegetables, citrus fruits, fatty fish, berries, yoghurt, apples, peaches, cauliflower, cabbage, broccoli, beans, and herbs in your diet.
  • Get optimal sleep; rest well.
  • Avoid smoking and alcohol consumption.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugars.

Habit Forming

No

Therapeutic Class

ANTINEOPLASTIC

Author Details

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Axiotem 20 mg Capsules works by binding to the DNA (deoxyribonucleic acid-genetic material of the cell) and interfering with cell growth and division. Thus, Axiotem 20 mg Capsules prevents tumours from growing.

Axiotem 20 mg Capsules may cause permanent infertility. Male patients should use effective contraception and refrain from fathering a child for up to three months after treatment is completed. Prior to treatment, it is recommended to seek sperm conservation advice from your doctor.

Yes, Axiotem 20 mg Capsules can cause neutropenia (low white blood cells count), lymphopenia (low lymphocytes count), thrombocytopenia (low platelet count). As a part of therapy, your doctor may monitor your blood profile.

Axiotem 20 mg Capsules may lead to hyperglycemia (Increased blood sugar). Consult your doctor if you are diabetic. Regularly monitor your blood sugar levels while taking Axiotem 20 mg Capsules.

The live vaccine may interact with Axiotem 20 mg Capsules. Do not have vaccinations or immunisations without talking to your doctor first.

Drug-Drug Interactions Checker List

  • ADALIMUMAB
  • BARICITINIB
  • CERTOLIZUMAB
  • GOLIMUMAB
  • INFLIXIMAB
  • LEFLUNOMIDE
  • UPADACITINIB
  • CLADRIBINE
  • CLOZAPINE
  • FINGOLIMOD
  • SIPONIMOD
  • TERIFLUNOMIDE
  • LOMITAPIDE
  • BCG VACCINE
  • INFLUENZA (LIVE ATTENUATED)
  • MEASLES (LIVE ATTENUATED)
  • ROTAVIRUS VACCINE
  • RUBELLA (LIVE ATTENUATED)
  • SMALLPOX VACCINE
  • TYPHOID VACCINE
  • VARICELLA (LIVE ATTENUATED)
  • YELLOW FEVER VACCINE
  • ZOSTER VACCINE LIVE

Special Advise

  • Axiotem 20 mg Capsules should be taken under strict medical supervision. The doctor will regularly monitor your condition while taking Axiotem 20 mg Capsules.
  • Your doctor may advise you to get routine blood tests done to monitor your liver function, electrolyte levels, and blood cell count.
  • Both male and female patients who are taking Axiotem 20 mg Capsules must use effective contraceptive precautions. Women of childbearing potential must use effective contraception during the treatment and for 6months after completion of the treatment. Male patients should avoid fathering a child while on treatment with Axiotem 20 mg Capsules and should use effective contraception during the treatment and for 3months after the treatment.

Disease/Condition Glossary

Brain tumour: A brain tumour is an uncontrolled, unregulated proliferation of cells in the brain. The cancerous cells can invade and destroy surrounding healthy tissue, including organs. The symptoms of a brain tumour differ depending on the tumour's location in the brain. Common symptoms include headaches, fits (seizures), feeling unwell or being sick all the time, behavioural changes, paralysis, sickness, eyesight or speech impairments.

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