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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
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Consume Type

PARENTERAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Azacytin 100Mg Inj

Azacytin 100Mg Inj belongs to the group of medicines called anti-metabolites used in adults with higher-risk myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. These conditions affect the bone marrow and could cause problems with normal blood cell production. 
 
Azacytin 100Mg Inj contains Azacitidine, which works by preventing cancer cells from growing. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, Azacytin 100Mg Inj may cause side effects such as nausea, vomiting, diarrhoea, constipation, weakness, headache, and injection site reactions. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Azacytin 100Mg Inj if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azacytin 100Mg Inj. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Azacytin 100Mg Inj

Myelodysplastic syndrome, chronic myelomonocytic leukaemia, and acute myeloid leukaemia.

Directions for Use

Azacytin 100Mg Inj will be administered by a qualified physician; do not self-administer.

Medicinal Benefits

Azacytin 100Mg Inj belongs to the group of medicines called anti-metabolites used to treat myelodysplastic syndromes, chronic myelomonocytic leukaemia, and acute myeloid leukaemia. Azacytin 100Mg Inj contains Azacitidine, a nucleoside metabolic inhibitor which works by preventing cancer cells from growing. It incorporates into the genetic material of the cells and interferes with the production of new DNA and RNA. This helps correct problems with the maturation and growth of young blood cells in the bone marrow, which causes myelodysplastic disorders.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Azacytin 100Mg Inj

  • Reduced blood count (red blood count, white blood count, and platelets)
  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Headache
  • Tiredness
  • Dizziness
  • Pneumonia
  • Injection site reaction (redness, pain or a skin reaction).

Drug Warnings

Do not use Azacytin 100Mg Inj if you are allergic to any of its components, have advanced liver cancer, or are breastfeeding. Inform the doctor if you have a low number of platelets, red or white blood cells, heart condition or heart attack, lung, kidney or liver diseases. Seek immediate medical attention if you experience symptoms of liver failure (jaundice, abdominal bloating, shaking, drowsiness, and easy bruising), kidney failure (back pain, increased thirst, swelling of legs and feet, reduced passing of water, dizziness, rapid pulse, nausea, vomiting, reduced appetite, confusion, fatigue or restlessness), fever, pneumonia (shortness of breath or chest pain accompanied with fever), low levels of platelets (bleeding such as blood in stools due to bleeding in the stomach), or allergic reaction (rash, difficulty breathing, itching, or swelling of lips).

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
AzacitidineFingolimod
Severe

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azacytin 100Mg Inj:
Taking Yellow fever vaccine with Azacytin 100Mg Inj can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azacytin 100Mg Inj and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
AzacitidineFingolimod
Severe
How does the drug interact with Azacytin 100Mg Inj:
The use of fingolimod in conjunction with Azacytin 100Mg Inj may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azacytin 100Mg Inj with Fingolimod can possibly result in an interaction, but it can be taken if your doctor has advised it. However, Consult a doctor immediately if you have a fever, chills, diarrhoea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineThalidomide
Severe
How does the drug interact with Azacytin 100Mg Inj:
Taking thalidomide together with Azacytin 100Mg Inj may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Azacytin 100Mg Inj together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
AzacitidineBaricitinib
Severe
How does the drug interact with Azacytin 100Mg Inj:
Taking baricitinib and Azacytin 100Mg Inj can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azacytin 100Mg Inj if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.
AzacitidineTeriflunomide
Severe
How does the drug interact with Azacytin 100Mg Inj:
Taking Azacytin 100Mg Inj with Teriflunomide can increase the risk of developing serious infections.

How to manage the interaction:
Although taking Azacytin 100Mg Inj and Teriflunomide together can cause an interaction, it can be taken if a doctor has suggested it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
AzacitidineTofacitinib
Severe
How does the drug interact with Azacytin 100Mg Inj:
Taking Azacytin 100Mg Inj with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Azacytin 100Mg Inj and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineCertolizumab
Severe
How does the drug interact with Azacytin 100Mg Inj:
Taking Azacytin 100Mg Inj with Certolizumab may raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azacytin 100Mg Inj with Certolizumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineGolimumab
Severe
How does the drug interact with Azacytin 100Mg Inj:
Taking Azacytin 100Mg Inj with Golimumab can raise the risk of severe infections.

How to manage the interaction:
Co-administration of Azacytin 100Mg Inj with Golimumab can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineEtanercept
Severe
How does the drug interact with Azacytin 100Mg Inj:
When Etanercept is used with Azacytin 100Mg Inj, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Azacytin 100Mg Inj, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AzacitidineCladribine
Severe
How does the drug interact with Azacytin 100Mg Inj:
The use of cladribine with Azacytin 100Mg Inj can increase the risk of infections.

How to manage the interaction:
Taking Azacytin 100Mg Inj with Cladribine together can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience a fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, contact a doctor immediately. Do not stop using any medications without talking to a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly to maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat a balanced diet.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Azacytin 100Mg Inj Substitute

Substitutes safety advice
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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Special Advise

  • Your doctor will recommend blood tests prior to treatment with Azacytin 100Mg Inj and at the start of each cycle to check blood cell count, liver and kidney functioning.
  • Women must use reliable contraception during treatment and for six months after receiving the last dose.
  • Male patients are advised to use effective contraception during treatment and for three months after stopping the treatment.
  • If you are due to undergo any surgery, including dental surgery, inform the doctor/dentist that you are on treatment with Azacytin 100Mg Inj.

Disease/Condition Glossary

Myelodysplastic syndromes: It is a group of cancers in which the immature blood cells in the bone marrow do not mature or become healthy blood cells. Signs and symptoms include shortness of breath, feeling tired or weak, pale skin, petechiae (flat, pinpoint spots under the skin caused by bleeding), and easy bleeding or bruising.

Chronic myelomonocytic leukaemia: It is a rare type of blood cancer in which there are too many monocytes (type of white blood cells) in the blood. Symptoms of chronic myelomonocytic leukaemia are tiredness, infections, bleeding or bruising easily, abdominal discomfort, weight loss, loss of appetite, sweating, skin rash, and bone and muscle pain.

Acute myeloid leukaemia: Acute myeloid leukaemia, also called acute myelogenous leukaemia or acute nonlymphocytic leukaemia, is the cancer of blood and bone marrow with excess immature white blood cells. Symptoms include fever, recurrent infections, fatigue, and easy bruising.

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