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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Whats That

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Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Apr-24

for this medicine

About Azadine-O Tablet 14's

Azadine-O Tablet 14's belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of acute myeloid leukaemia in adults who improved after chemotherapy but could not complete intensive curative therapy. Acute myeloid leukaemia is a type of cancer that forms in the blood-forming cells of the bone marrow.

Azadine-O Tablet 14's contains Azacitidine, which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.
 
In some cases, Azadine-O Tablet 14's may cause side effects such as nausea, vomiting, diarrhoea, constipation, fatigue and abdominal pain. Most of these side effects may not require medical attention and resolve gradually over time. Do not be reluctant to talk with your doctor if any of the side effects persist or worsen.
 
Do not use Azadine-O Tablet 14's if you are pregnant or breastfeeding. Consult a doctor immediately if you become pregnant during treatment with Azadine-O Tablet 14's. This medicine is not recommended for children as safety and effectiveness have not been established. Inform your doctor about your health condition and medications to rule out any side effects/interactions.

Uses of Azadine-O Tablet 14's

Acute myeloid leukaemia

Directions for Use

Take Azadine-O Tablet 14's with or without food. Swallow the medicine as a whole with water; do not crush or chew it.

Medicinal Benefits

Azadine-O Tablet 14's belongs to the group of anti-cancer medicines called demethylation agents indicated for continued treatment of adult patients with acute myeloid leukaemia who achieved first complete remission (all signs and symptoms of cancer have disappeared) or complete remission with incomplete blood count recovery following intensive induction chemotherapy and are not able to complete intensive curative therapy. Azadine-O Tablet 14's contains Azacitidine, a nucleoside metabolic inhibitor which works by interfering with the growth of cancer cells, which are eventually destroyed by the body. It helps the bone marrow in the production of normal blood cells and kills abnormal cells in the bone marrow.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Azadine-O Tablet 14's

  • Nausea
  • Vomiting
  • Diarrhoea
  • Constipation
  • Dizziness
  • Fatigue
  • Abdominal pain
  • Decreased appetite
  • Arthralgia (joint pain)

Drug Warnings

Do not take Azadine-O Tablet 14's if you are allergic to any of its components or if you are breastfeeding. Inform the doctor if you have liver or kidney problems. Seek medical attention if you experience symptoms of neutropenia/low white blood cells (fever or chills, feeling very tired or weak, body aches, and unusual headache) or thrombocytopenia/low platelet count (unusual bleeding or bruising). Consult the doctor if you are pregnant, plan to become pregnant, or if you plan to father a child.

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
AzacitidineEfalizumab
Severe

Drug-Drug Interactions

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AzacitidineYellow fever vaccine
Critical
How does the drug interact with Azadine-O Tablet:
Taking Yellow fever vaccine with Azadine-O Tablet can increase the risk of infection.

How to manage the interaction:
Although there is a possible interaction between Azadine-O Tablet and the Yellow fever vaccine, you can take these medicines together if prescribed by a doctor. If you notice any signs of infection, it's important to contact a doctor right away. Do not stop using any medications without consulting a doctor.
AzacitidineEfalizumab
Severe
How does the drug interact with Azadine-O Tablet:
Using efalizumab together with Azadine-O Tablet may increase the risk of serious infections.

How to manage the interaction:
Taking Azadine-O Tablet with Efalizumab together can result in an interaction, but it can be taken if a doctor has advised it. If you have any of these symptoms - complications, infection, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, pain or burning during urination - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineThalidomide
Severe
How does the drug interact with Azadine-O Tablet:
Taking thalidomide together with Azadine-O Tablet may increase the risk of blood clots and other complications.

How to manage the interaction:
Although taking thalidomide and Azadine-O Tablet together can result in an interaction, it can be taken if a doctor has prescribed it. However, consult the doctor immediately if you experience symptoms such as chest pain, shortness of breath, difficulty breathing, coughing up blood, sudden loss of vision, pain, redness or swelling in an arm or leg, and numbness or weakness on one side of the body. Do not discontinue any medications without consulting a doctor.
AzacitidineNatalizumab
Severe
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with Natalizumab can raise the risk of severe infections.

How to manage the interaction:
There may be a possibility of interaction between Azadine-O Tablet and Natalizumab, but it can be taken if prescribed by a doctor. However, if you have any of these symptoms- fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, blood in phlegm(a thick secretion in the airway during disease and inflammation), losing weight, or pain while peeing, progressive weakness on one side of the body, clumsiness of limbs, disturbance of vision, confusion, or changes in thinking, memory and personality, make sure to contact a doctor immediately. Do not stop using any medications without a doctor's advice.
AzacitidineVoclosporin
Severe
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with Voclosporin may lead to a higher chance of severe infections and certain cancers, such as skin cancer and lymph gland cancer (lymphoma).

How to manage the interaction:
Taking Azadine-O Tablet with Voclosporin together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptoms - fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in coughing fluid, weight loss, red or inflamed skin, body sores, and pain or burning during urination, make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineAdalimumab
Severe
How does the drug interact with Azadine-O Tablet:
Taking Adalimumab with Azadine-O Tablet may raise the risk of severe infections.

How to manage the interaction:
Taking Azadine-O Tablet with Adalimumab together can result in an interaction, but it can be taken if a doctor has advised it. However, if you have any of these symptom's fever, chills, diarrhea, sore throat, muscle aches, difficulty breathing, weight loss, pain or burning while peeing - make sure to contact a doctor right away. Do not stop using any medications without a doctor's advice.
AzacitidineDeferiprone
Severe
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with Deferiprone can increase the risk of developing serious infections.

How to manage the interaction:
Co-administration of Azadine-O Tablet with Deferiprone can result in an interaction, but it can be taken if a doctor has advised it. However, consult a doctor immediately if you have a fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not stop using any medications without talking to a doctor.
AzacitidineTofacitinib
Severe
How does the drug interact with Azadine-O Tablet:
Taking Azadine-O Tablet with tofacitinib can increase the risk of developing serious infections.

How to manage the interaction:
Although there is a possible interaction between Azadine-O Tablet and Tofacitinib, you can take these medicines together if prescribed by a doctor. However, consult a doctor immediately if you experience fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, weight loss, red or irritated skin, body sores, or discomfort or burning during urination. Do not discontinue any medications without consulting a doctor.
AzacitidineEtanercept
Severe
How does the drug interact with Azadine-O Tablet:
When Etanercept is used with Azadine-O Tablet, the likelihood or severity of infection may increase.

How to manage the interaction:
There may be a possibility of interaction between Etanercept and Azadine-O Tablet, but it can be taken if prescribed by a doctor. However, if you develop fever, chills, diarrhea, sore throat, muscular pains, shortness of breath, blood in phlegm, weight loss, red or irritated skin, body sores, or discomfort or burning during urination, consult a doctor immediately. Do not discontinue any medications without a doctor's advice.
AzacitidineBaricitinib
Severe
How does the drug interact with Azadine-O Tablet:
Taking baricitinib and Azadine-O Tablet can raise the risk of developing serious infections.

How to manage the interaction:
Although there is an interaction, baricitinib can be taken with Azadine-O Tablet if prescribed by the doctor. However, if you experience fever, chills, diarrhea, sore throat, muscular aches, shortness of breath, blood in your coughing fluid, weight loss, red or irritated skin, body sores, and discomfort or burning when you urinate, consult a doctor. Do not discontinue any medication without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat a healthy diet and exercise regularly as it helps maintain proper weight.
  • Avoid smoking and alcohol consumption.
  • Include vegetables and fruits in your diet.
  • Avoid fast food, fried food, processed meats, refined carbs and added sugar.
  • Get optimal sleep; rest well.
  • Drink enough water and eat fibre-rich foods, vegetables and fruits.

Habit Forming

No

Therapeutic Class

CHEMOTHERAPY

Azadine-O Tablet 14's Substitute

Substitutes safety advice
  • Azashine 300 Tablet 14's

    by Others

    1405.71per tablet
  • Azacytin Oral 300 mg Tablet 14's

    by Others

    1165.57per tablet
  • MDS-O 300 mg Tablet 14's

    by Others

    761.37per tablet
  • Azatend-O 300 mg Tablet 14's

    by Others

    1544.53per tablet
  • Xpreza 300 mg Tablet 14's

    by Others

    1288.57per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Special Advise

  • If you are a female, you should take a pregnancy test prior to the start of the treatment. Use reliable contraception to prevent pregnancy during treatment and for 6 months after the last dose.
  • Male patients with partners of reproductive potential should use effective contraception during treatment and for 3 months after stopping the treatment.
  • If the powder from the medicine comes in contact with your skin, wash the area well with soap and water immediately.
  • If the powder from the medicine comes in contact with mucous membranes (eyes or mouth), flush the area with water immediately.

Disease/Condition Glossary

Acute myeloid leukaemia: Acute myeloid leukaemia, also called acute myelogenous leukaemia or acute nonlymphocytic leukaemia, is the cancer of blood and bone marrow with excess immature white blood cells. Symptoms include fever, recurrent infections, fatigue, and easy bruising.

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