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Written By Veda Maddala , M Pharmacy
Reviewed By Santoshini Reddy G , M Pharmacy

About Benadryl Cough Formula Syrup, 450 ml

Benadryl Cough Formula Syrup, 450 ml belongs to a class of medications called ‘expectorants’ used to treat cough. Coughing (dry or productive) is the body’s way of clearing irritants (like allergens, mucus, or smoke) from airways and preventing infection. There are two types of coughs, namely: Dry cough and chesty cough. A dry cough is tickly and doesn't produce any vicious or thick mucus, while a chesty cough (wet cough) means mucous or sputum is produced to help clear your airways.

Benadryl Cough Formula Syrup, 450 ml is a combination of four drugs, namely: Ammonium chloride (expectorants), Diphenhydramine hydrochloride (antihistamine), Sodium citrate (mucolytic), and ethanol. Ammonium chloride works by increasing the volume of fluid in the airways, reducing the stickiness of mucus. Diphenhydramine hydrochloride works by blocking the action of histamine, a substance responsible for causing allergic reactions. Sodium citrate works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Thereby, it helps to cough out easily. Ethanol acts as a preservative.

Take Benadryl Cough Formula Syrup, 450 ml as prescribed by your doctor. You are advised to take Benadryl Cough Formula Syrup, 450 ml for as long as your doctor has prescribed it for you based on your medical condition. In some cases, you may experience drowsiness, dizziness, dry mouth, nervousness, stomach pain, diarrhoea, or constipation. Most of these side effects of Benadryl Cough Formula Syrup, 450 ml do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Benadryl Cough Formula Syrup, 450 ml or any other medicines, please tell your doctor. Benadryl Cough Formula Syrup, 450 ml is not recommended for children below 2 years of age unless advised by a doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Benadryl Cough Formula Syrup, 450 ml. Benadryl Cough Formula Syrup, 450 ml should be used with caution in elderly patients due to the increased risk of side effects. Drive only if you are alert as Benadryl Cough Formula Syrup, 450 ml may cause dizziness. You are recommended to avoid alcohol consumption with Benadryl Cough Formula Syrup, 450 ml as it may increase drowsiness or dizziness.

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Uses of Benadryl Cough Formula Syrup, 450 ml

Cough

Medicinal Benefits

Benadryl Cough Formula Syrup, 450 ml contains Ammonium chloride, Diphenhydramine hydrochloride, Sodium citrate and ethanol used to treat cough. Ammonium chloride is an expectorant that increases the volume of fluid in the airways, reduces the stickiness of mucus and helps to remove it from the airways. Diphenhydramine hydrochloride is an antihistamine (anti-allergic drug) that blocks the action of histamine, a substance responsible for causing allergic reactions.  It helps to provide relief from symptoms of allergy such as sneezing, running nose, watery eyes, itching, swelling, and congestion or stiffness. Sodium citrate is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Thereby, it helps to cough out easily. Ethanol acts as a preservative.

Side Effects of Benadryl Cough Formula Syrup, 450 ml

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Nervousness
  • Stomach pain
  • Diarrhoea
  • Constipation

Directions for Use

Take Benadryl Cough Formula Syrup, 450 ml with or without food as advised by your doctor. Shake the bottle well before use. Take the prescribed dose by mouth using the measuring cup/dosing syringe/dropper provided by the pack.

Storage

Store in a cool and dry place away from sunlight

Drug Warnings

If you are allergic to Benadryl Cough Formula Syrup, 450 ml or any other medicines, please tell your doctor. Benadryl Cough Formula Syrup, 450 ml is not recommended for children below 2 years of age unless advised by a doctor. If you are pregnant or breastfeeding, it is advised to inform your doctor before using Benadryl Cough Formula Syrup, 450 ml. Benadryl Cough Formula Syrup, 450 ml should be used with caution in elderly patients due to increased risk of side effects. Avoid using Benadryl Cough Formula Syrup, 450 ml if you have taken medicines such as linezolid, phenelzine, selegiline, rasagiline, isocarboxazid, tranylcypromine and methylene blue injection in the past 14 days. If you have asthma, inform your doctor before taking Benadryl Cough Formula Syrup, 450 ml. Drive only if you are alert as Benadryl Cough Formula Syrup, 450 ml may cause dizziness. You are recommended to avoid alcohol consumption with Benadryl Cough Formula Syrup, 450 ml as it may increase drowsiness or dizziness.

Therapeutic Class

EXPECTORANT AND COUGH PRODUCTS

Drug-Drug Interactions

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DiphenhydramineThioridazine
Critical
DiphenhydraminePotassium citrate
Critical

Drug-Drug Interactions

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DiphenhydramineThioridazine
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
When Thioridazine is taken with Benadryl Cough Formula Syrup, 450 ml, it can slow down the way Benadryl Cough Formula Syrup, 450 ml is broken down in the body.

How to manage the interaction:
Taking Benadryl Cough Formula Syrup, 450 ml with Thioridazine is not recommended, please consult your doctor before taking it. It can be taken if your doctor advises it. Do not stop taking any medication without consulting your doctor.
DiphenhydraminePotassium citrate
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Taking Benadryl Cough Formula Syrup, 450 ml and Potassium citrate together can increase the risk of stomach ulcers, bleeding, and gastrointestinal injury.

How to manage the interaction:
Taking Benadryl Cough Formula Syrup, 450 ml with Potassium citrate is not recommended, as it may lead to an interaction, it can be taken if prescribed by the doctor. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, consult the doctor immediately. Do not discontinue any medications without a doctor's advice.
DiphenhydramineEliglustat
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
When Benadryl Cough Formula Syrup, 450 ml is taken with Eliglustat, it can cause a decrease in metabolism.

How to manage the interaction:
Taking Benadryl Cough Formula Syrup, 450 ml with Eliglustat is not recommended, please consult your doctor before taking it. It can be taken if prescribed by your doctor. Do not stop taking any medication without consulting your doctor.
DiphenhydramineSodium oxybate
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Taking Benadryl Cough Formula Syrup, 450 ml with Sodium oxybate can enhance the sedative effects on the central nervous system.

How to manage the interaction:
Taking Benadryl Cough Formula Syrup, 450 ml with Sodium oxybate is not recommended, but it can be taken if prescribed by a doctor. However contact your doctor if you experience shortness of breath, increased sweating, palpitations, or confusion. Do not stop using any medications without consulting a doctor.
DiphenhydraminePotassium chloride
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Taking Benadryl Cough Formula Syrup, 450 ml with Potassium chloride can increase the risk of stomach ulcers.

How to manage the interaction:
Taking Benadryl Cough Formula Syrup, 450 ml with Potassium chloride is not recommended, as it can lead to an interaction, but it can be taken if a doctor has prescribed it. However, if you experience severe stomach pain, bloating, sudden lightheadedness or dizziness, nausea, vomiting (especially with blood), decreased hunger, or dark, tarry stools, contact your doctor. Do not stop taking any medication without consulting your doctor.
EthanolAcitretin
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Coadministration of Acitretin with Benadryl Cough Formula Syrup, 450 ml can increase the risk and severity of birth defects.

How to manage the interaction:
Taking Acitretin with Benadryl Cough Formula Syrup, 450 ml together is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience headaches, nausea, vomiting, and visual disturbances, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
EthanolMetronidazole
Critical
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Drinking alcohol while taking Metronidazole can increase the risk or severity of side effects.

How to manage the interaction:
Taking Metronidazole with Benadryl Cough Formula Syrup, 450 ml is avoided as it can result in an interaction, it can be taken if your doctor has advised it. However, if you experience flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, palpitation, low blood pressure, dizziness, lightheadedness, blurred vision, and confusion, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
DiphenhydramineTamoxifen
Severe
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Benadryl Cough Formula Syrup, 450 ml reduces the blood levels and effectiveness of tamoxifen.

How to manage the interaction:
Although taking Benadryl Cough Formula Syrup, 450 ml with Tamoxifen can possibly reduce the effectiveness of Tamoxifen, they can be taken together if prescribed by your doctor. Do not stop using any medications without first talking to your doctor.
DiphenhydramineBrexpiprazole
Severe
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Benadryl Cough Formula Syrup, 450 ml increases the blood levels of Brexpiprazole. This increases the risk of Side effects.

How to manage the interaction:
Taking Benadryl Cough Formula Syrup, 450 ml with Brexpiprazole together can possibly result in an interaction, but it can be taken if your doctor has advised it. If you notice any of these symptoms - feeling tired, unusual muscle movements, muscle spasms, shaking or jerking in your arms and legs, feeling dizzy or lightheaded, or fainting - contact your doctor right away. Do not stop using any medications without talking to a doctor.
DiphenhydramineEsketamine
Severe
How does the drug interact with Benadryl Cough Formula Syrup, 450 ml:
Taking Benadryl Cough Formula Syrup, 450 ml with Esketamine can increase the risk of adverse effects.

How to manage the interaction:
Co-administration of Benadryl Cough Formula Syrup, 450 ml with Esketamine can result in an interaction, but it can be taken if your doctor has advised it. However, contact your doctor if you experience drowsiness, confusion, or difficulty concentrating. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • WARFARIN
  • CHLORAMPHENICOL
  • PROPANTHELINE
  • METOCLOPRAMIDE
  • PREGABALIN

Diet & Lifestyle Advise

  • Avoid dairy products such as milk as it may increase mucus production. Also, avoid processed or refined foods. Instead replace baked foods, fried foods, white bread, white pasta, french fries, sugary desserts and chips with green leafy vegetables.
  • Drink plenty of fluids to avoid dry throat while you have a cough. It also helps loosen mucus. 
  • Avoid citrus fruits as they may worsen the cough. Eat fruits rich in water content such as pears, watermelon, peaches and pineapples.

Habit Forming

No

Special Advise

If the symptoms persist or worsen after using Benadryl Cough Formula Syrup, 450 ml for 1 week, please consult a doctor.

Author Details

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Disease/Condition Glossary

Cough: Coughing is a body’s way of clearing irritants (like allergens, mucus or smoke) from airways and preventing infection. Coughs may be dry or productive. A productive cough (wet cough) brings up sputum (phlegm, mucus and other matter) from the lungs. Cough is commonly caused as a response to allergy or viral infection but coughing up mucus is possibly an indication of infection in the respiratory tract. If you are coughing thick, solid white mucus, it indicates you may have a bacterial infection in the airways. If the mucus is clear or light-coloured, it indicates you may have allergies or minor infection in the respiratory tract and yellow or green mucus indicates a respiratory infection.

Benadryl Cough Formula Syrup, 450 ml Substitute

Substitutes safety advice
  • Benadryl Cough Formula Syrup, 150 ml

    1.02per tablet
  • Benadryl Cough Formula Syrup, 50 ml

    1.72per tablet
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