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Written By Santoshini Reddy G , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer

Glenmark Pharmaceuticals Ltd

Consume Type

ORAL

Return Policy

Not Returnable

Expires on or after

Jan-27

for this medicine

About Bepofly 180 Tablet

Bepofly 180 Tablet belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used together with lifestyle changes and certain cholesterol-lowering medicines to decrease bad cholesterol in patients with heart disease or familial heterozygous hypercholesterolemia (an inherited condition in which cholesterol cannot be removed from the body normally).
 
Bepofly 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.
 
In some cases, Bepofly 180 Tablet may cause side effects such as anaemia, gout, and pain in the shoulders, arms or legs. Most of these side effects may not require medical attention and resolve gradually over time. However, you are advised to talk to your doctor if the side effects persist or worsen.
 
Do not take Bepofly 180 Tablet if you are pregnant or breastfeeding. Bepofly 180 Tablet is not recommended for children below 18 years as the safety and effectiveness have not been established. Inform the doctor regarding your health condition and medicines you are taking to rule out any possible side effects/interactions.

Uses of Bepofly 180 Tablet

High cholesterol

Directions for Use

Take Bepofly 180 Tablet with food or between meals or as advised by the doctor. Swallow the medicine as a whole with a glass of water; do not chew or break it.

Medicinal Benefits

Bepofly 180 Tablet belongs to a group of medicines called adenosine triphosphate-citrate lyase (ACL) inhibitors used in addition to the cholesterol-lowering diet in adult patients with primary hypercholesterolaemia (high cholesterol) or mixed dyslipidaemia (imbalance of lipids), which are conditions that cause a high cholesterol level in the blood. Bepofly 180 Tablet contains Bempedoic acid, which works by blocking an enzyme (ATP citrate lyase) needed for the production of cholesterol. This helps block the production of cholesterol in the liver and increases the removal of LDL cholesterol. Thereby, it helps decrease bad cholesterol in the body.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Bepofly 180 Tablet

  • Anaemia (low red blood cells)
  • Gout (increased levels of uric acid)
  • Pain in arms, legs, or shoulders
  • Muscle spasms

Drug Warnings

Do not take Bepofly 180 Tablet if you are allergic to any of its components, if you are pregnant or breastfeeding. Inform the doctor if you have/had gout, severe kidney or liver problems, or tendon problems. Consult the doctor immediately if you become pregnant during treatment with Bepofly 180 Tablet . Seek medical attention if you experience symptoms of gout (tender joints, joint redness, severe foot pain, especially in the toe joint, warm joints, and swelling), tendon problems (pain, swelling, tears and inflammation of tendons), or tendon rupture (hear or feel a snap or pop in a tendon area, bruising right after an injury in a tendon area, or are unable to move the affected area or put weight on the affected area).

Drug-Drug Interactions

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Bempedoic acidDeflazacort
Severe
Bempedoic acidCinoxacin
Severe

Drug-Drug Interactions

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Bempedoic acidDeflazacort
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet and Deflazacort can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Deflazacort if prescribed by the doctor. However, consult a doctor immediately if you experience pain or swelling in joints. Avoid exercise or use of the affected area. Do not stop using any medications without talking to a doctor.
Bempedoic acidCinoxacin
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Cinoxacin with Bepofly 180 Tablet can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Bepofly 180 Tablet with Cinoxacin together can result in an interaction, it can be taken if a doctor has prescribed it. However, if you feel pain or swelling in joints, consult your doctor immediately. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidEnoxacin
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet and enoxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Enoxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidNorfloxacin
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet and norfloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Norfloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bepofly 180 Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidCiprofloxacin
Severe
How does the drug interact with Bepofly 180 Tablet:
Taking Bepofly 180 Tablet with Ciprofloxacin may can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Ciprofloxacin if prescribed by the doctor. However, if you experience pain, inflammation, or swelling in joints, consult a doctor immediately. Exercise and using the affected area should be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidGatifloxacin
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet and gatifloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Gatifloxacin if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor immediately. Avoid or limit exercising or using the impacted area. Do not discontinue any medications without a doctor's advice.
Bempedoic acidOfloxacin
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet and Ofloxacin can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although taking Bepofly 180 Tablet and Ofloxacin together may cause an interaction, they can be taken if prescribed by a doctor. Consult a doctor if you have pain, swelling, or inflammation in a muscle location such as the back of the ankle, shoulder, or biceps. Exercising or using the injured area should also be avoided. Do not discontinue any medications without consulting a doctor.
Bempedoic acidDexamethasone
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet with Dexamethasone can result in tendinitis (a condition in which the tissue connecting muscle to bone becomes inflamed) and tendon rupture (injuries to the soft tissues that connect muscles and joints).

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Dexamethasone if prescribed by the doctor. However, if you experience pain, inflammation, or swelling of a tendon area such as the back of the ankle, biceps, shoulder, hand, or thumb, stop taking Bepofly 180 Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue the medication without consulting a doctor.
Bempedoic acidMethylprednisolone
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet with Methylprednisolone can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Methylprednisolone if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of joints, consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.
Bempedoic acidNalidixic acid
Severe
How does the drug interact with Bepofly 180 Tablet:
Co-administration of Bepofly 180 Tablet and nalidixic acid can increase the risk of tissue injury near muscles and joints.

How to manage the interaction:
Although there is an interaction, Bepofly 180 Tablet can be taken with Nalidixic acid if prescribed by the doctor. However, if you experience pain, swelling, or inflammation of a tendon area such as the back of the ankle, shoulder, or biceps, stop taking Bepofly 180 Tablet and consult a doctor. Exercise and using the impacted area should both be avoided. Do not discontinue any medications without a doctor's advice.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Follow a cholesterol-lowering diet.
  • Exercise regularly. It helps in maintaining proper weight and lowers cholesterol.
  • Limit salt and sugar intake.
  • Avoid smoking and alcohol consumption. 
  • Choose healthy fats and cut down on trans fats.
  • Include omega-3 fatty acids, fibre-rich food, fruits and vegetables.
  • Get active by doing any physical activity such as swimming, brisk walking or jogging. Take stairs instead of elevators/lifts.

Habit Forming

No

Therapeutic Class

MISCELLANEOUS

Bepofly 180 Tablet Substitute

Substitutes safety advice
  • Bempesta 180 mg Tablet 10's

    by Others

    23.63per tablet
  • Brillo 180 Tablet 10's

    by Others

    23.67per tablet
  • Bemdac 180 mg Tablet 10's

    by Others

    26.10per tablet
  • Bemzire 180 Tablet 10's

    by Others

    18.54per tablet
  • Bempify 180 Tablet 10's

    by Others

    21.60per tablet

Drug-Diseases Interactions

verifiedApollotooltip
No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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Drug-Drug Interactions Checker List

  • ATORVASTATIN
  • FLUVASTATIN
  • PITAVASTATIN
  • PRAVASTATIN
  • ROSUVASTATIN
  • SIMVASTATIN
  • BOSENTAN
  • FIMASARTAN
  • GLECAPREVIR
  • GRAZOPREVIR
  • VOXILAPREVIR

Special Advise

  • Before starting the treatment, you should confirm you are not pregnant. Also, use effective contraception, as advised by your doctor during treatment with Bepofly 180 Tablet .
  • Bepofly 180 Tablet treatment may increase liver enzyme levels. Your doctor may suggest tests to check your liver functioning while on treatment with this medicine.

Disease/Condition Glossary

High cholesterol: High cholesterol levels in the blood might build up on the walls of the arteries, leading to blockage of blood flow to the heart and other body parts, which could cause heart disease, heart attack or stroke. Cholesterol is mainly of two types, namely, 'bad cholesterol' and 'good cholesterol'. Bad cholesterol comprises low-density lipoprotein (LDL) and triglycerides (TG), which deposit fat in the arteries, leading to their blockage. Good cholesterol consists of high-density lipoprotein (HDL), which prevents the deposition of fats. Risk factors of high cholesterol are high-fat diet, obesity, lack of physical exercise, and smoking.

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