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Written By Veda Maddala , M Pharmacy
Reviewed By Sunny S , MBBS
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Consume Type :

ORAL

Return Policy :

Not Returnable

About Bigamuci-AB Tablet

Bigamuci-AB Tablet belongs to the class of drugs called ‘mucolytic agents’ (cough/sputum thinner) primarily used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing, or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes).

Bigamuci-AB Tablet is a combination of two drugs, namely: Acebrophylline (mucolytic and bronchodilator) and Acetylcysteine (mucolytic agent/sputum thinner). Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine belongs to the class of mucolytic agents (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Bigamuci-AB Tablet breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.

Take Bigamuci-AB Tablet as prescribed. Your doctor will recommend how often you take Bigamuci-AB Tablet based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, drowsiness, and cool and moist skin. Most of these side effects of Bigamuci-AB Tablet do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Bigamuci-AB Tablet or any other medicines, please tell your doctor. Bigamuci-AB Tablet is not recommended for children below 14 years of age. Drink plenty of fluids to thin mucus and lubricate your throat while taking Bigamuci-AB Tablet. Bigamuci-AB Tablet is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Bigamuci-AB Tablet. Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking Bigamuci-AB Tablet and contact your doctor immediately. Do not take Bigamuci-AB Tablet if you have a heart rhythm disorder that causes fast heartbeats. Avoid taking Bigamuci-AB Tablet if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Bigamuci-AB Tablet.

Uses of Bigamuci-AB Tablet

Chronic obstructive pulmonary disease (COPD)

Directions for Use

Take Bigamuci-AB Tablet with or without food as advised by your doctor. Swallow it as a whole with a glass of water. Do not break, crush or chew it.

Medicinal Benefits

Bigamuci-AB Tablet is a combination of two drugs, namely: Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in the lungs, windpipe, and nose. Bigamuci-AB Tablet breakdown the acid mucopolysaccharide fibers that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and make breathing easier by opening airways.

Storage

Keep Bigamuci-AB Tablet out of the sight and reach of children.

Drug Warnings

If you are allergic to Bigamuci-AB Tablet or any other medicines, please tell your doctor. Bigamuci-AB Tablet is not recommended for children below 14 years of age. Regular monitoring of potassium levels is recommended while taking Bigamuci-AB Tablet as it may cause low potassium levels in the blood. Bigamuci-AB Tablet is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Bigamuci-AB Tablet. Severe skin reactions such as Stevens-Johnson syndrome (a serious and rare disorder of skin and mucus membranes) or toxic epidermal necrolysis (skin blistering or skin peeling) have been rarely reported in some patients. However, if you notice any skin rash worsening with mucosal lesions or blisters, stop taking Bigamuci-AB Tablet and contact your doctor immediately. Do not take Bigamuci-AB Tablet if you have heart rhythm disorder that causes fast heartbeats. Avoid taking Bigamuci-AB Tablet if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack, or kidney or liver diseases. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, or kidney or liver insufficiency, inform your doctor before taking Bigamuci-AB Tablet.

Drug-Drug Interactions

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Drug-Food Interactions

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Diet & Lifestyle Advise

  • Eat foods rich in potassium such as bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.
  • Drink plenty of fluids every day to thin mucus which makes it easier to cough out.
  • Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas and potatoes with skin.
  • Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks like red bull.
  • Eat protein-rich foods such as meat, fish (particularly salmon, sardines and mackerel), eggs and poultry.
  • Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
  • Quit smoking as it may reduce the effectiveness of the Bigamuci-AB Tablet and irritate the lungs worsening breathing problem.

Side Effects of Bigamuci-AB Tablet

  • Diarrhoea
  • Stomach pain
  • Nausea
  • Vomiting
  • Runny nose
  • Dizziness
  • Drowsiness
  • Heartburn
  • Skin rash
  • Hives
  • Itching
  • Cool and moist skin

Habit Forming

No

Therapeutic Class

MUCOLYTIC AGENTS

Author Details

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Drug-Diseases Interactions

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FAQs

Bigamuci-AB Tablet contains Acebrophylline and Acetylcysteine. Acebrophylline belongs to the class of bronchodilators with additional mucolytic properties and works by relaxing muscles and widening the airways of the lungs. Acetylcysteine is a mucolytic agent (cough/sputum thinner) that works by thinning and loosening phlegm (mucus) in lungs, windpipe and nose. Bigamuci-AB Tablet breakdown the acid mucopolysaccharide fibres that make the mucus (sputum) thinner and less dense/viscous removing sputum efficiently by coughing. However, the viscosity of sputum remains low for as long as treatment is maintained. Together, they help to cough out easily and makes breathing easier by opening airways.

Bigamuci-AB Tablet should be used with caution in patients suffering from epilepsy (fits) as it may worsen the condition. Therefore, inform your doctor if you have a history of fits before taking Bigamuci-AB Tablet so that the dose may be adjusted or an alternate medicine may be prescribed.

You are not recommended to take Bigamuci-AB Tablet with antibiotics such as tetracycline, amoxicillin, amikacin and gentamicin at the same time as it may reduce the effectiveness of antibiotics. However, if you are supposed to take these medicines together, maintain a time gap of a minimum of 2 hours between taking Bigamuci-AB Tablet and antibiotics. However, please consult a doctor before using Bigamuci-AB Tablet with antibiotics or any other medicines.

You are recommended to avoid taking Bigamuci-AB Tablet if you are allergic to acebrophylline, ambroxol, theophylline or suffering from irregular heartbeats, hemodynamic instability (unstable blood pressure), low blood pressure, liver or kidney disorders or had a heart attack. However, inform your doctor if you have any of these conditions before taking Bigamuci-AB Tablet.

No, you are not recommended to smoke while taking Bigamuci-AB Tablet as it may reduce the effectiveness of Bigamuci-AB Tablet and also damage your lungs. Long term smoking may cause breathing problems like asthma, bronchitis and COPD. Quitting smoking is the best way to keep your lungs healthy.

You are recommended to avoid histamine rich foods such as tomatoes, wine and processed foods as it may cause histamine intolerance by affecting the way histamine is broken down in the body leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching and rhinitis (runny and stuffy nose). Therefore, if you are allergic to histamine or cannot tolerate food and drinks rich in histamine, please inform your doctor before taking Bigamuci-AB Tablet.

No, you are not recommended to stop taking Bigamuci-AB Tablet without consulting your doctor as it may worsen the condition of your cough and other breathing problems causing recurring symptoms. Therefore, take Bigamuci-AB Tablet for as long as your doctor has prescribed it, and if you experience any difficulty while taking Bigamuci-AB Tablet, please consult your doctor.

No, Bigamuci-AB Tablet does not relieve sudden asthma symptoms. Therefore, it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

Drug-Drug Interactions Checker List

  • FUROSEMIDE
  • ALLOPURINOL
  • CIMETIDINE
  • CIPROFLOXACIN
  • ERYTHROMYCIN
  • AMOXICILLIN
  • DOXYCYCLINE
  • TETRACYCLINE
  • GENTAMICIN
  • AMIKACIN
  • NEOMYCIN
  • DILTIAZEM
  • VERAPAMIL
  • ISOPRENALINE
  • THIABENDAZOLE
  • PREDNISONE
  • ETHINYLESTRADIOL
  • GLYCERYL TRINITRATE
  • DEXTROMETHORPHAN
  • CODEINE

Special Advise

  • Regular blood tests are recommended while taking Bigamuci-AB Tablet to monitor the levels of Bigamuci-AB Tablet and potassium in the blood.
  • Bigamuci-AB Tablet may affect the test results of ketones in urine and salicylate (like aspirin) in the blood. Therefore, inform your doctor that you are taking Bigamuci-AB Tablet before undergoing any laboratory tests.
  • Bigamuci-AB Tablet does not relieve sudden asthma symptoms, so it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.

Disease/Condition Glossary

Chronic obstructive pulmonary disease (COPD): It is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation of the lining of bronchial tubes). The major cause of COPD is smoking tobacco. Also, long-term exposure to fumes and chemicals may lead to COPD. The symptoms include chronic cough, shortness of breath or wheezing (whistle sound while breathing).

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Alcohol

Unsafe

Avoid consumption of alcohol with Bigamuci-AB Tablet as it may reduce the effectiveness of Bigamuci-AB Tablet and increase drowsiness. Please consult a doctor before consuming alcohol with Bigamuci-AB Tablet.

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Pregnancy

Unsafe

Bigamuci-AB Tablet is not recommended for pregnant women. Please consult a doctor before using Bigamuci-AB Tablet if you are pregnant.

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Breast Feeding

Caution

It is unknown whether Bigamuci-AB Tablet is excreted in human milk. Please consult a doctor before taking Bigamuci-AB Tablet if you are breastfeeding.

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Driving

Safe if prescribed

Bigamuci-AB Tablet usually does not affect your ability to drive or operate machinery.

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Liver

Caution

Take Bigamuci-AB Tablet with caution, especially if you have a history of Liver diseases/conditions. The dose may be adjusted by your doctor as required.

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Kidney

Caution

Take Bigamuci-AB Tablet with caution, especially if you have a history of Kidney diseases/conditions. The dose may be adjusted by your doctor as required.

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Children

Caution

Bigamuci-AB Tablet is not recommended for children below 14 years of age. Please consult a doctor before giving Bigamuci-AB Tablet to children.

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