Bigphylin-N Tablet 10's

Bigphylin-N Tablet 10's belongs to the class of drugs called ‘mucolytic agents’ (cough/sputum thinner) primarily used to prevent and treat symptoms of chronic obstructive pulmonary disease (COPD) such as shortness of breath, coughing or wheezing (whistling sound while breathing). COPD is a group of lung diseases with emphysema (shortness of breath) and chronic bronchitis (inflammation in the lining of bronchial tubes).

Bigphylin-N Tablet 10's is a combination of two drugs, namely: Acebrophylline (mucolytic and bronchodilator) and N-Acetylcysteine (mucolytic agent/sputum thinner). Acebrophylline works by relaxing muscles and widening the airways of the lungs. N-Acetylcysteine works by thinning and loosening phlegm (mucus) in the lungs, windpipe and nose. Together, Bigphylin-N Tablet 10's helps to cough out easily and makes breathing easier by opening airways.

Swallow Bigphylin-N Tablet 10's as a whole with a glass of water. Do not crush, chew or break it. Your doctor will recommend how often you take Bigphylin-N Tablet 10's based on your medical condition. Some people may experience diarrhoea, nausea, vomiting, runny nose, dizziness, heartburn, stomach pain, skin rash, and drowsiness. Most of these side effects of Bigphylin-N Tablet 10's do not require medical attention and gradually resolve over time. However, if the side effects persist or worsen, please consult your doctor.

If you are allergic to Bigphylin-N Tablet 10's or any other medicines, please tell your doctor. Bigphylin-N Tablet 10's is not recommended for use during pregnancy. If you are breastfeeding, it is advised to inform your doctor before taking Bigphylin-N Tablet 10's. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Bigphylin-N Tablet 10's. Bigphylin-N Tablet 10's is not recommended for children below 14 years of age.

• Diarrhoea, 
• Stomach pain
• Nausea
• Vomiting
• Runny nose
• Dizziness
• Drowsiness
• Heartburn

Drug-Drug Interactions: Bigphylin-N Tablet 10's may interact with water pills (e.g. furosemide), medicines used to treat gout (e.g. allopurinol), antacid (e.g. cimetidine), antibiotics (e.g. ciprofloxacin, erythromycin, amoxicillin, doxycycline, tetracycline, gentamicin, amikacin, neomycin), drugs used to lower high blood pressure (e.g. diltiazem, verapamil), heart-related medicines (e.g. isoprenaline), anthelmintic (e.g. thiabendazole),  corticosteroids (e.g. prednisone), oral contraceptives (e.g. ethinylestradiol), medicines used to treat chest pain (e.g. glyceryl trinitrate) and cough suppressants (e.g. dextromethorphan, codeine).

Drug-Food Interactions: If you are allergic to histamine, avoid histamine rich foods such as tomatoes, wine and processed foods as it may cause histamine intolerance leading to symptoms such as flushing (redness of the skin), migraine headaches, skin rash, itching and rhinitis (runny and stuffy nose). Also, avoid intake of alcohol with Bigphylin-N Tablet 10's as it may increase drowsiness. Also, avoid or limit the intake of caffeine with Bigphylin-N Tablet 10's as it may cause side effects.

Drug-Disease Interactions: Avoid taking Bigphylin-N Tablet 10's if you have low blood pressure, irregular heartbeats, hemodynamic instability (unstable blood pressure), had a heart attack. If you have hyperthyroidism (overactive thyroid), irregular heartbeats, viral infections, heart failure, asthma, high blood pressure, fits, gastric or duodenal ulcers, heart diseases, kidney or liver insufficiency, inform your doctor before taking Bigphylin-N Tablet 10's.

• FUROSEMIDE
• ALLOPURINOL
• CIMETIDINE
• CIPROFLOXACIN
• ERYTHROMYCIN
• AMOXICILLIN
• DOXYCYCLINE
• TETRACYCLINE
• GENTAMICIN
• AMIKACIN
• NEOMYCIN
• DILTIAZEM
• VERAPAMIL
• ISOPRENALINE
• THIABENDAZOLE
• PREDNISONE
• ETHINYLESTRADIOL
• GLYCERYL TRINITRATE
• DEXTROMETHORPHAN
• CODEINE

• Eat foods rich in potassium such as bananas, asparagus, oranges, potatoes, avocados, dark leafy greens and beetroots as potassium is important for lung function and a potassium deficiency may cause breathing problems.
• Drink plenty of fluids every day to thin mucus which makes it easier to cough out.
• Maintain a diet that includes complex carbohydrates such as lentils, beans, barley, oats, quinoa, bran, peas and potatoes with skin.
• Limit or avoid the intake of caffeinated drinks such as tea, coffee, soda, and energy drinks like red bull.
• Eat protein-rich foods such as meat, fish (particularly salmon, sardines and mackerel), eggs and poultry.
• Exercise regularly to strengthen your breathing muscles and boost your immune system. Learning breathing exercises will help you move more air in and out of your lungs.
• Quit smoking as it may irritate the lungs and worsen breathing problems.

• Regular blood tests are recommended while taking Bigphylin-N Tablet 10's to monitor the levels of Bigphylin-N Tablet 10's and potassium in the blood.
• Bigphylin-N Tablet 10's may affect the test results of ketones in urine and salicylate (like aspirin) in the blood. Therefore, inform your doctor that you are taking Bigphylin-N Tablet 10's before undergoing any laboratory tests.
• Bigphylin-N Tablet 10's does not relieve sudden asthma symptoms, so it is advised to carry a rescue inhaler always to treat sudden asthma symptoms.