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  3. Bioclar Dry Syrup 30 ml

Written By Bayyarapu Mahesh Kumar , M Pharmacy
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

Online payment accepted

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Manufacturer/Marketer :

Cadila Pharmaceuticals Ltd

Consume Type :

ORAL

Return Policy :

Not Returnable

Expires on or after :

NPPA :

Regulated

About Bioclar Dry Syrup

Bioclar Dry Syrup belongs to a group of medicine called macrolide antibiotics derived from Saccharopolyspora erythraea (originally called Streptomyces erythreus), used to treat a wide range of bacterial infections. A bacterial infection is a condition in which bacteria grow in the body and cause infection. It can target any body part and multiple very quickly. Antibiotics inhibit the growth of microorganisms and are given to treat bacterial infections.

Bioclar Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Bioclar Dry Syrup helps in the prevention of infections.

Like all medicines, Bioclar Dry Syrup may cause some common side effects, including feeling sick (nausea), diarrhoea and being sick (vomiting), loss of appetite, bloating and indigestion, headaches and difficulty sleeping. Most of these side effects do not require medical attention and gradually resolve over time. However, if you notice any of these side effects persist or worsen your child’s condition, inform your doctor immediately.

Inform your doctor about your child's entire medical history. Other drugs or supplements should not be combined with Bioclar Dry Syrup unless prescribed by a doctor. Even if your child is feeling better, do not miss any dose and complete the entire course of medication. Stopping the medication too soon may cause the infection to recur or worsen.

Uses of Bioclar Dry Syrup

Bacterial infections

Directions for Use

Oral Suspension: Administer the prescribed dose to the child using the measuring cup/dosing syringe/dropper. Shake the bottle well before use.

Medicinal Benefits

Bioclar Dry Syrup belongs to the macrolide class of antibiotics which is effective against a wide range of bacteria, including gram-negative, gram-positive bacteria, anaerobes, and some parasites (like Balantidium coli and Entamoeba species). It is prescribed for treating various bacterial infections, including chest infections such as pneumonia, skin problems such as cellulitis, and ear infections; on the other hand, it is also used in combination with other medicines to treat duodenal ulcers caused by H. pylori (Helicobacter pylori).

Storage

Store in a cool and dry place away from sunlight
Side effects of Bioclar Dry Syrup 30 ml
  • Regularly brush and floss your teeth.
  • Rinse your mouth with water and baking soda a solution to neutralize acid in the mouth. This makes your food taste as it should.
  • Drink plenty of water or non-caffeinated drinks to prevent dry mouth which may lead to altered taste.
  • Try ginger, peppermint, fruit or green teas, lemonade, ginger ale or fruit juice to help mask unpleasant tastes.
  • Try sucking on sugar-free ice pops or ice cubes to prevent dry mouth.
Here are the precise steps to cope with diarrhoea caused by medication usage:
  • Inform Your Doctor: Notify your doctor immediately about your diarrhoea symptoms. This allows them to adjust your medication or provide guidance on managing side effects.
  • Stay Hydrated: Drink plenty of fluids to replace lost water and electrolytes. Choose water, clear broth, and electrolyte-rich drinks. Avoid carbonated or caffeinated beverages to effectively rehydrate your body.
  • Follow a Bland Diet: Eat easy-to-digest foods to help firm up your stool and settle your stomach. Try incorporating bananas, rice, applesauce, toast, plain crackers, and boiled vegetables into your diet.
  • Avoid Trigger Foods: Steer clear of foods that can worsen diarrhoea, such as spicy, fatty, or greasy foods, high-fibre foods, and dairy products (especially if you're lactose intolerant).
  • Practice Good Hygiene: Maintain good hygiene to prevent the spread of infection. To stay healthy, wash your hands frequently, clean and disinfect surfaces regularly, and avoid exchanging personal belongings with others.
  • Take Anti-Diarrheal Medications: If your doctor advises, anti-diarrheal medications such as loperamide might help manage diarrhoea symptoms. Always follow your doctor's directions.
  • Keep track of your diarrhoea symptoms. If they don't get better or worse or are accompanied by severe stomach pain, blood, or dehydration signs (like extreme thirst or dark urine), seek medical help.

Drug Warnings

Before using Bioclar Dry Syrup, let your doctor know about all your children's medical conditions, sensitivities, and all medications used. Do not use any other drugs or supplements with Bioclar Dry Syrup unless prescribed by the doctor. Iron and antacid (like magnesium hydroxide and aluminium hydroxide) may bind to Bioclar Dry Syrup in the gastrointestinal tract, lowering its efficiency. So, a gap of at least 2 hours should be maintained between intake of Bioclar Dry Syrup and iron supplements and antacids.

Drug-Drug Interactions

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Drug-Drug Interactions

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How does the drug interact with Bioclar Dry Syrup 30 ml:
Co-administration of Bioclar Dry Syrup 30 ml and Simvastatin can increase the blood levels and effects of Simvastatin. This can increase the risk of side effects such as liver damage and rhabdomyolysis(which involves the breakdown of skeletal muscle tissue).

How to manage the interaction:
Taking Bioclar Dry Syrup 30 ml and Simvastatin together is not recommended as it can lead to an interaction, it can be taken if advised by your doctor. However, if you experience any symptoms like muscle pain, tenderness, or weakness, fever or dark colored urine, chills, joint pain or swelling, unusual bleeding or bruising, skin rash, itching, loss of appetite, fatigue, nausea, vomiting, and yellowing of the skin or eyes, contact your doctor immediately. Do not discontinue any medications without first consulting your doctor.
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Isavuconazole is taken with Bioclar Dry Syrup 30 ml, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Bioclar Dry Syrup 30 ml and Isavuconazole can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like nausea, vomiting, or diarrhoea, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinDroperidol
Critical
How does the drug interact with Bioclar Dry Syrup 30 ml:
Co-administration of Droperidol with Bioclar Dry Syrup 30 ml can increase the risk of an irregular heart rhythm.

How to manage the interaction:
Taking Bioclar Dry Syrup 30 ml with Droperidol can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience dizziness, lightheadedness, fainting, shortness of breath, or heart palpitation, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinTerfenadine
Critical
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Terfenadine is taken with Bioclar Dry Syrup 30 ml, the amount of Terfenadine in the blood can go up.

How to manage the interaction:
Co-administration of Bioclar Dry Syrup 30 ml and Terfenadine can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bioclar Dry Syrup 30 ml:
Coadministration of colchicine with Bioclar Dry Syrup 30 ml may increase the blood levels of colchicine, increasing the risk of serious side effects.

How to manage the interaction:
Taking Colchicine with Bioclar Dry Syrup 30 ml is not recommended, they can be taken together if advised by your doctor. However, contact your doctor if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet. Do not stop taking any medications without consulting a doctor.
ClarithromycinLomitapide
Critical
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Lomitapide is taken with Bioclar Dry Syrup 30 ml, it can lower the metabolism of Lomitapide.

How to manage the interaction:
Co-administration of Bioclar Dry Syrup 30 ml and Lomitapide can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like diarrhea, nausea, vomiting, stomach pain or discomfort, indigestion, gas, constipation, and liver damage, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Nimodipine is taken with Bioclar Dry Syrup 30 ml, it can increase the risk of side effects.

How to manage the interaction:
Co-administration of Bioclar Dry Syrup 30 ml and Nimodipine is not recommended as it can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like irregular heart rhythm, swelling, and low blood pressure, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinConivaptan
Critical
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Bioclar Dry Syrup 30 ml is taken with Conivaptan, it can lower the rate at which Conivaptan is broken down in the body.

How to manage the interaction:
Taking Bioclar Dry Syrup 30 ml with Convivaptan can result in an interaction, it should be taken only if a doctor has advised it. However, if you experience swallowing, trouble speaking, muscle weakness, trouble controlling body movements, confusion, mood changes, or seizures, contact a doctor immediately. Do not discontinue any medications without consulting a doctor.
ClarithromycinSaquinavir
Critical
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Bioclar Dry Syrup 30 ml is taken with Saquinavir, increases the risk of an irregular heart rhythm.

How to manage the interaction:
Co-administration of Bioclar Dry Syrup 30 ml and Saquinavir can lead to an interaction, it can be taken if advised by a doctor. However, if you experience any symptoms like dizziness, lightheadedness, fainting, shortness of breath, or heart palpitations, consult a doctor immediately. Do not stop using any medications without a doctor's advice.
ClarithromycinAstemizole
Critical
How does the drug interact with Bioclar Dry Syrup 30 ml:
When Astemizole is taken with Bioclar Dry Syrup 30 ml, it can cause a decrease in the metabolism of Astemizole.

How to manage the interaction:
Taking Bioclar Dry Syrup 30 ml with Astemizole is not recommended, please consult your doctor before taking it.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • It would be best to give probiotics after taking the full course of Bioclar Dry Syrup to restore some healthy bacteria in the intestine that may have been killed. Taking probiotics after antibiotic treatment can reduce the risk of antibiotic-associated diarrhoea. Certain fermented foods like yoghurt, cheese, sauerkraut and kimchi can help restore the intestine's good bacteria.
  • The BRAT diet (bananas, rice, apple sauce, toast) can help with diarrhoea from antibiotics.
  • Give plenty of water to the child. Staying hydrated is important, especially when you’re child sick.
  • Eating a broad range of plant-based foods such as vegetables, fruits, nuts, seeds, pulses and wholegrains helps to build a healthy gut microbiome.
  • Avoid feeding too many calcium-enriched foods and drinks because they may interfere with the functioning of Bioclar Dry Syrup.

Habit Forming

No

Therapeutic Class

ANTI- BACTERIALS

Drug-Diseases Interactions

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CLARITHROMYCIN-125MGOther bacterial intestinal infections
Severe
CLARITHROMYCIN-125MGToxic liver disease
Moderate

Drug-Diseases Interactions

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CLARITHROMYCIN-125MGOther bacterial intestinal infections
Severe
How does the disease interact with Bioclar Dry Syrup 30 ml:
Almost all antibacterial medications have been associated with cases of Clostridioides difficile-associated diarrhoea (CDAD), formerly known as pseudomembranous colitis. It can vary from mild diarrhoea to deadly colitis. Clindamycin and lincomycin are two of the most frequent those involved.

How to manage the interaction:
Anti-bacterial medicines may cause Clostridioides difficile-associated diarrhea (CDAD) ranging from mild diarrhoea to colitis. Therapy should be administered with caution in patients with history of gastrointestinal disease, particularly colitis and pseudomembranous colitis. Appropriate fluid and electrolyte management, protein supplementation, antibacterial treatment of C difficile is advised.
CLARITHROMYCIN-125MGToxic liver disease
Moderate
How does the disease interact with Bioclar Dry Syrup 30 ml:
Patients on Bioclar Dry Syrup 30 ml have been reported to experience hepatic dysfunction, including elevated liver enzymes, cholestatic and/or hepatocellular hepatitis, with or without jaundice. Using this medication to patients with hepatic impairment requires caution and close monitoring. If hepatitis signs and symptoms appear, treatment must be stopped.

How to manage the interaction:
Caution and monitoring is advised if Bioclar Dry Syrup 30 ml is used in patients with liver impairment. Treatment must be discontinued immediately if signs and symptoms of hepatitis such as anorexia, jaundice, dark urine, pruritus, or tender abdomen occur. The use of Bioclar Dry Syrup 30 ml is contraindicated in patients with a history of cholestatic jaundice or liver impairment associated with the prior use of Bioclar Dry Syrup 30 ml.
CLARITHROMYCIN-125MGOther disorders of kidney and ureter, not elsewhere classified
Moderate
How does the disease interact with Bioclar Dry Syrup 30 ml:
The kidney and liver are the organs that eliminate of Bioclar Dry Syrup 30 ml the most. In individuals with severe renal impairment (CrCl 30 mL/min), a lower dose or longer dosing intervals are advised. Patients with mild to moderate renal impairment often do not require dosage modifications, while medication accumulation may happen if there is concurrent liver illness. It is suggested to monitor.

How to manage the interaction:
Dose adjustment may be needed in patients with severe kidney impairment. Monitoring is advised in patients with mild to moderate kidney impairment.
CLARITHROMYCIN-125MGMyasthenia gravis and other myoneural disorders
Moderate
How does the disease interact with Bioclar Dry Syrup 30 ml:
Myasthenia gravis symptoms have been observed to worsen and new myasthenic syndrome symptoms appear when macrolide antibiotics are used, according to reports. In patients who have a history of myasthenia gravis, therapy with these medicines should be used with caution.

How to manage the interaction:
Therapy should be administered cautiously in patients with a history of myasthenia gravis as the use of macrolide antibiotics has been reported to exacerbate symptoms of myasthenia gravis.
CLARITHROMYCIN-125MGAbnormal results of function studies
Moderate
How does the disease interact with Bioclar Dry Syrup 30 ml:
Macrolides have been associated with an increase in the QT interval and occasional cases of arrhythmia. Patients with known QT interval prolongation, ventricular cardiac arrhythmia, including torsades de pointes, patients with proarrhythmic conditions like untreated hypokalemia or hypomagnesemia, clinically significant bradycardia, or patients taking other drugs that prolong the QT interval should avoid taking Bioclar Dry Syrup 30 ml and erythromycin.

How to manage the interaction:
Bioclar Dry Syrup 30 ml should be avoided in patients with known prolongation of the QT interval, abnormal heart rhythm, uncorrected low potassium or low magnesium, clinically significant slow heart rate, or receiving other drugs that prolong the QT interval.

FAQs

Bioclar Dry Syrup contains Clarithromycin (antibiotic). It inhibits the protein synthesis process required for the growth of the bacterial cell. As a result, bacterial cells are not able to reproduce and grow. Thus, Bioclar Dry Syrup helps in the prevention of infections.

After taking antibiotics such as Bioclar Dry Syrup, some people get thrush, a fungal infection. This is due to the fact that antibiotics kill the regular, harmless bacteria that serve to protect you from thrush.

Bioclar Dry Syrup treats only bacterial infections. It will not work for viral infections such as the common cold, or flu.

No, Bioclar Dry Syrup is a macrolide antibiotic. It can be taken by people who are allergic to penicillin with a doctor's advice only.

Side effects are rare with Bioclar Dry Syrup and do not usually last long. They will get better after a day or two. If those side effects persist, reach out to the doctor immediately.

Drug-Drug Interactions Checker List

  • AZITHROMYCIN
  • AMOXICILLIN+CLAVULANIC ACID
  • SIMVASTATIN
  • ATORVASTATIN
  • WARFARIN
  • DIGOXIN
  • COLCHICINE
  • THEOPHYLLINE
  • BUDESONIDE/FORMOTEROL
  • CARBAMAZEPINE
  • PHENYTOIN
  • ERGOTAMINE
  • DIHYDROERGOTAMINE

Disease/Condition Glossary

Bacterial infections: A bacterial infection is a condition in which harmful bacteria enter, multiply, and infect our body. It can target any body part and multiple very quickly. The symptoms of bacterial infection are fever, chills, and fatigue. Bacteria are of various forms comprising, commonly spherical, rod, and spiral-shaped. Bacterial infections vary from minor illnesses like sore throat and ear infections to severe brain infections like meningitis and encephalitis. A few harmful bacteria that cause infections include Streptococcus, Staphylococcus, and E. coli. Anyone can become infected with a bacterial infection. But, people with weak immune systems or taking immunosuppressive medicine are more prone to get bacterial infections.

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