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Written By Lakshmithulasi Yarragunta , Pharm-D (PB)
Reviewed By Dr Aneela Siddabathuni , MPharma., PhD
Non returnable*
COD available

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Whats That

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Synonym :

PAMIDRONATE DISODIUM

Composition :

PAMIDRONATE-90MG

Manufacturer/Marketer :

Uni Sankyo Ltd

Consume Type :

PARENTERAL

Return Policy :

Not Returnable

Expires on or after :

About Biodronate Inj 90Mg

Biodronate Inj 90Mg is a hypocalcemic agent that belongs to the bisphosphonates class. It is mainly used in lowering blood calcium levels and bone metastases/lesions in cancer patients. Besides this, it is also used to treat mild to moderate Paget's disease. Hypercalcemia (increased calcium levels) is a condition in which the calcium level in your blood is elevated due to certain conditions. Paget’s disease is a serious condition of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak, and brittle.

Biodronate Inj 90Mg contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, bone strength and bone health.

Biodronate Inj 90Mg may cause certain side effects such as injection site reactions, stomach pain, loss of appetite, nausea, vomiting, fever, headache, dizziness, mouth sores, constipation, and cough. Most of these side effects do not require medical attention and gradually resolve over time. However, if these side effects persist for a longer period, please consult your doctor. Biodronate Inj 90Mg is a parenteral preparation. A trained healthcare professional will administer it. Hence, do not self-administer.

Biodronate Inj 90Mg should be avoided if you are allergic to it or any other components present in it. Before receiving Biodronate Inj 90Mg, let your doctor know about all your medical conditions, sensitivities, and medications you are using to rule out any interactions. Biodronate Inj 90Mg should be used under caution if you have/had kidney disease, liver problems, bone disorders, musculoskeletal pain, and high blood pressure. Biodronate Inj 90Mg is not recommended for use in pregnant women due to foetal harm, and whether this medicine can be used for breastfeeding mothers is unknown. Hence, inform your doctor if you are pregnant or are breastfeeding before receiving Biodronate Inj 90Mg. This medicine is not recommended for use in children as safety and efficacy have not been established.

Uses of Biodronate Inj 90Mg

Hypercalcemia in Malignancy, Paget’s disease, Osteolytic bone metastases of breast cancer.

Directions for Use

Biodronate Inj 90Mg will be administrated by a healthcare professional. Do not self-administer.

Medicinal Benefits

Biodronate Inj 90Mg contains Pamidronate as an active ingredient, which belongs to the class of bisphosphonates. It works by inhibiting the osteoclast bone resorption, which causes bone breakdown. When bone is broken down, the calcium in the bone is released into the bloodstream. Thus, it helps retain the normal density of bones and restores bone integrity, strength, and health.

Storage

Store in a cool and dry place away from sunlight

Side Effects of Biodronate Inj 90Mg

  • Injection site reactions
  • Nausea
  • Vomiting
  • Dizziness
  • Constipation
  • Stomach pain
  • Loss of appetite
  • Headache
  • Cough
  • Fever
  • Mouth sores

Drug Warnings

Biodronate Inj 90Mg should be avoided if you are allergic to it or any other components present in it. Before receiving Biodronate Inj 90Mg, let your doctor know about all your medical conditions, sensitivities, and medication history you are using to rule out any interactions. Biodronate Inj 90Mg should be used under caution if you have/had kidney disease, liver problems, bone disorders, musculoskeletal pain, and high blood pressure. Biodronate Inj 90Mg is not recommended for use in pregnant women due to foetal harm, and whether this medicine can be used for breastfeeding mothers is unknown. Hence, inform your doctor if you are pregnant or are breastfeeding before receiving Biodronate Inj 90Mg. This medicine is not recommended for use in children as safety and efficacy have not been established.

Drug-Drug Interactions

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Pamidronic acidHuman immunoglobulin
Severe

Drug-Drug Interactions

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Pamidronic acidHuman immunoglobulin
Severe
How does the drug interact with Biodronate Inj 90Mg:
Taking Human immunoglobulin with Biodronate Inj 90Mg, may raise the risk of kidney problems.

How to manage the interaction:
Co-administration of Human immunoglobulin with Biodronate Inj 90Mg can result in an interaction, but it can be taken if a doctor has advised it. However, if you experience nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, or an irregular heart rhythm, consult a doctor. Do not discontinue any medications without consulting a doctor.

Drug-Food Interactions

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No Drug - Food interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Food Interactions

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Diet & Lifestyle Advise

  • Try to consume calcium and vitamin D in their diet as it helps make stronger bones and avoid everyday osteoporosis dangers.
  • Regular exercise like weight-bearing exercises are important for maintaining bone health.
  • Calcium is important for making bones strong. Vitamin D is equally important, which helps ensure calcium absorption and retention in bones, so take food high in calcium and vitamins.

Habit Forming

No

Therapeutic Class

HYPOCALCEMIC AGENTS

Biodronate Inj 90Mg Substitute

Substitutes safety advice
  • Cedroin 90mg Injection

    by Others

    2861.80per tablet
  • Pamimed 90 mg Injection 1's

    by Others

    2788.00per tablet

Drug-Diseases Interactions

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No Drug - Disease interactions found in our database. Some may be unknown. Consult your doctor for what to avoid during medication.

Drug-Diseases Interactions

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FAQs

Biodronate Inj 90Mg contains Pamidronate as an active ingredient, which works by inhibiting osteoclast bone resorption that causes bone breakdown.

Biodronate Inj 90Mg helps regulate the calcium level in the blood. This maintains bone formation and also helps the body to reverse bone loss. Due to this, the number of cells that damage bones becomes comparatively less.

Drug-Drug Interactions Checker List

  • THALIDOMIDE
  • FUROSEMIDE
  • TORSEMIDE
  • GENTAMICIN
  • NEOMYCIN
  • LITHIUM

Special Advise

  • Your doctor may suggest certain blood tests, like serum calcium, CBC, and kidney function tests, to check for any unpleasant effects.
  • Bone density scans are used to check bone mineral density (BMD).
  • Clinical monitoring of serum electrolyte concentrations may also be advised.

Disease/Condition Glossary

Hypercalcemia: Hypercalcemia is when the calcium level in the blood is higher than normal. Too much calcium in the blood can weaken the bones, create kidney stones, and interfere with working the heart and brain. It is usually a result of overactive parathyroid glands. Symptoms include increased thirst and urination, stomach pain, nausea, bone pain, muscle weakness, confusion and fatigue.

Paget's disease: Paget's disease is a chronic disease of bone that disrupts the replacement of old bone tissue with new bone tissue, resulting in the new bone that is abnormally shaped, weak and brittle. It most commonly occurs in the pelvis, skull, spine, and legs. Symptoms include bone pain, joint pain (especially in the back, hips, and knees), headache, enlargement and bowing of the thighs (femurs) and lower legs (tibias), and enlargement of the skull in the area of the forehead.

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